Jingjing Jiao, Ksenia Chezar, Xuefeng Zhang, Donghai Wang, Wenqing Cao, Challa Bindu, Wei Chen, Antonio Galvao Neto, Patrick Henn, Irene Riahi, Hanlin L Wang, David J Papke, Lei Zhao, Yue Xue, Xiaoyan Liao, Xuchen Zhang
Postinfantile giant cell hepatitis (PIGCH) is a rare hepatitis pattern in adults with variable etiologies and clinical outcomes. We conducted a multi-institutional retrospective study to define the clinicopathologic characteristics of patients with PIGCH. A total of 70 PIGCH cases were identified and reviewed for pathological features, including fibrosis, cholestasis, inflammation, steatosis, necrosis, and apoptosis, as well as the distribution of giant cells and the maximum number of giant cells per high-power field...
August 6, 2023: Modern Pathology