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https://www.readbyqxmd.com/read/27876998/occurrence-of-knemidokoptes-mutans-and-laminosioptes-cysticola-in-backyard-poultry-in-india
#1
C Sreedevi, P Ramesh, P Mala Kondaiah, N Lakshmi Rani, M Abhishek
Birds reared in backyard poultry farming system are more prone to parasitic infestation resulting in economic losses to rural community. The present study reports occurrence of Knemidokoptes mutans and Laminosioptes cysticola mites in a male Aseel bird. Clinical signs observed in the affected bird include hyperkeratosis with whitish film layer on shank and hock region of legs. Focal areas of sloughing of skin with oozing of blood were also observed on the back and on the legs. Examination of skin scrapings from the affected sites revealed different developmental stages of Knemidokoptes mutans and Laminosioptes cysticola mites...
December 2016: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/27865803/leukoplakia-a-diagnostic-and-management-algorithm
#2
REVIEW
Alessandro Villa, Sook Bin Woo
Oral white lesions are frequently encountered in daily practice. Most white lesions are benign (eg, reactive keratoses or keratoses from inflammatory conditions) and the diagnosis is usually evident from the clinical presentation and histopathology. Leukoplakia is a common condition characterized by an increased risk for malignant transformation. Histopathology of leukoplakia can disclose hyperkeratosis with dysplasia or carcinoma or hyperkeratosis or parakeratosis without dysplasia. Treatment depends on demographic, social, clinical, and histopathologic factors...
October 26, 2016: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27864007/six-generations-of-epidermolytic-palmoplantar-keratoderma-associated-with-a-krt9-r163w-mutation
#3
Peng Wang, Xiao-Jing Kang, Xiao-Hui Tang, Jian-Yong Liu, Wen-Zheng Li, Wei-Jia Wang, Sheng-Nan Liang, Yan-Yan Feng, Yuan Ding, Wen-Jing Chen
Epidermolytic palmoplantar keratoderma (EPPK) is a rare autosomal dominant skin disorder characterized by diffuse hyperkeratosis on the palms and soles. Whole-exome sequencing (WES) has become a powerful tool for the detection of rare causal variants of Mendelian disorders. However, no causal gene for EPPK in the Uygur population has been identified until now, and no treatment exists than can address the underlying pathology.WES analysis was undertaken on two individuals from a large Uygur EPPK pedigree whose disease locus mapped to 17q21...
November 2016: Cancer Genetics
https://www.readbyqxmd.com/read/27852057/novel-mutations-c-28g-t-p-ala10ser-and-c-189g-t-p-glu63asp-in-wdr62-associated-with-early-onset-acanthosis-and-hyperkeratosis-in-a-patient-with-autosomal-recessive-microcephaly-type-2
#4
Santasree Banerjee, Huishuang Chen, Hui Huang, Jing Wu, Zhiyun Yang, Weiping Deng, Dongna Chen, Jianlian Deng, Yan Su, Yang Li, Chao Wu, Ye Wang, Hao Zeng, Yiming Wang, Xunhua Li
Microcephaly (MCPH) is a developmental disorder characterized by reduced brain size and intellectual disability. A proportion of microcephaly is caused by defects in a single gene. Microcephaly 2 (MCPH2) is one of the most frequent subtypes of MCPH.WD repeat-containing protein 62 gene (WDR62) is the most frequently mutated gene in MCPH2 patients. Phenotypes involving dermatological changes in MCPH2 have not been reported. We have identified and investigated a 5-year-old Chinese girl with markedly reduced brain size (86% of normal size), intellectual disability and psychomotor developmental delay...
November 10, 2016: Oncotarget
https://www.readbyqxmd.com/read/27847737/treatment-of-nevoid-basal-cell-carcinoma-syndrome-a-case-report
#5
Dong-Uk Seo, Su-Gwan Kim, Ji-Su Oh, Jae-Seek You
Nevoid basal cell carcinoma syndrome (NBCCS), also known as Gorlin syndrome, is characterized by various embryological deformities and carcinoma formation. It is caused by PTCHI gene mutations and is autosomal dominantly inherited. Some of the main symptoms of NBCCS are multiple basal cell carcinomas, multiple keratocystic odontogenic tumors (KCOTs) of the mandible, hyperkeratosis of the palmar and plantar, skeletal deformity, calcification of the falx cerebri, and facial defomity. Recurrent KCOT is the main symptom of NBCCS and is present in approximately 90% of patients...
October 2016: Journal of the Korean Association of Oral and Maxillofacial Surgeons
https://www.readbyqxmd.com/read/27846965/dermoscopic-findings-in-hyperkeratosis-lenticularis-perstans
#6
Manuel Valdebran, David Terrero, Ruzeng Xue
No abstract text is available yet for this article.
December 2016: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/27837338/analysis-of-debrided-and-non-debrided-invasive-squamous-cell-carcinoma-skin-lesions-by-in-vivo-reflectance-confocal-microscopy-before-and-after-therapy
#7
Wenzhong Xiang, Jianzhong Peng, Xiuzu Song, Aie Xu, Zhigang Bi
Hyperkeratosis hinders the application of reflectance confocal microscopy (RCM) to image squamous cell carcinoma (SCC). Not all lesions with SCC show hyperkeratosis, and these lesions can be directly imaged. However, lesions with hyperkeratosis can be treated by debriding the hyperkeratotic surface for further imaging. RCM was used to investigate patients with suspected SCC. Lesions without obvious keratosis underwent direct RCM examinations. Lesions with obvious keratosis were treated by debriding the hyperkeratotic surface...
November 12, 2016: Lasers in Medical Science
https://www.readbyqxmd.com/read/27832414/herpetiform-keratitis-and-palmoplantar-hyperkeratosis-warning-signs-for-richner-hanhart-syndrome
#8
Diogo C Soares, Mariana N Stroparo, Yu C Lian, Cristina Y Takakura, Sabrina Wolf, Regina Betz, Chong A Kim
Richner-Hanhart syndrome (RHS, tyrosinemia type II) is a rare, autosomal recessive inborn error of tyrosine metabolism caused by tyrosine aminotransferase deficiency. It is characterized by photophobia due to keratitis, painful palmoplantar hyperkeratosis, variable mental retardation, and elevated serum tyrosine levels. Patients are often misdiagnosed with herpes simplex keratitis. We report on a a boy from Brazil who presented with bilateral keratitis secondary to RHS, which had earlier been misdiagnosed as herpes simplex keratitis...
November 10, 2016: Journal of Inherited Metabolic Disease
https://www.readbyqxmd.com/read/27824223/onychomycosis-by-paecilomyces-lilacinus
#9
Paolo Pontini, Alberto Gorani, Stefano Veraldi
The authors describe a case of onychomycosis by Paecilomyces lilacinus in an 81-year-old Caucasian woman. The infection was characterized clinically by yellow-brown discoloration of the nail plate, distal-lateral onycholysis and subungual hyperkeratosis of the first left toenail. Microscopic examination showed irregular hyphae. Four cultures showed the development of lilac and powdery colonies. Conidiophores with divergent long narrow terminal phialides were observed at microscopic examination of culture samples...
December 2016: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/27817781/-a-gene-study-of-a-family-with-hidrotic-ectodermal-dysplasia
#10
Wen-Xing Qiao, Li Liu
OBJECTIVE: To investigate the clinical features and molecular mechanism of hidrotic ectodermal dysplasia (HED). METHODS: A clinical and gene study was performed for five generations (91 people) in the family of one proband with HED. GJB6 gene detection was performed for 7 patients and 3 normal people in this family. RESULTS: Among the 91 people in this family, there were 17 HED patients, who were manifested as having dysplasia of the fingernails and toenails and sparse or absent hair or body hair...
November 2016: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/27816291/atrophying-pityriasis-versicolor-as-an-idiosyncratic-t%C3%A2-cell-mediated-response-to-malassezia-a-case-series
#11
Jonathan Michael Stephen Levy, Cynthia Magro
BACKGROUND: Atrophying pityriasis versicolor (PV), first described in 1971, is a rare variant in which lesions appear atrophic. OBJECTIVE: We sought to determine the pathophysiology of atrophying PV. METHODS: A retrospective chart review identified 6 cases of atrophying PV. In all cases, routine light microscopy, an elastic tissue stain, and immunohistochemical assessment for the expression of CD3, CD4, CD8, GATA3 and CXCR3 was performed. RESULTS: All cases demonstrated hyperkeratosis with intracorneal infiltration by pathogenic hyphal forms as well as epidermal attenuation and papillary dermal elastolysis...
November 2, 2016: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/27816244/association-of-anatomical-characteristics-of-teats-with-quarter-level-somatic-cell-count
#12
J F Guarín, M G Paixão, P L Ruegg
Mastitis occurs after bacteria successfully traverse the teat orifice and cause an intramammary infection. Anatomical characteristics of the teat are potential risk factors for infection. The objective of this study was to identify potential associations between anatomical characteristics of teats and quarter-level somatic cell count (QSCC) from cows on larger dairy farms in Wisconsin. Teat dimensions (length and diameter at the teat barrel and apex) were measured, and hyperkeratosis scores were assessed for 3,713 quarters of 959 cows on 9 dairy farms...
November 2, 2016: Journal of Dairy Science
https://www.readbyqxmd.com/read/27811637/cutaneous-horn-of-the-eyelid-in-13-cases
#13
Renelle Pointdujour-Lim, Molly R Marous, Celine E Satija, Alexzandra M Douglass, Ralph C Eagle, Jerry A Shields, Carol L Shields
INTRODUCTION: Cutaneous horn of the eyelid is uncommon. The authors evaluate the features of benign, premalignant, and malignant tumors at the base of cutaneous horn of the eyelid. OBJECTIVE: To describe the clinical and histopathologic features of cutaneous horn of the eyelid. DESIGN: A retrospective analysis of 13 cases of cutaneous horn of the eyelid treated between 1994 and 2014 was performed. PARTICIPANTS: Thirteen patients participated in this study...
November 2, 2016: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/27809902/preliminary-analysis-of-psoroptes-ovis-transcriptome-in-different-developmental-stages
#14
Man-Li He, Jing Xu, Ran He, Neng-Xing Shen, Xiao-Bin Gu, Xue-Rong Peng, Guang-You Yang
BACKGROUND: Psoroptic mange is a chronic, refractory, contagious and infectious disease mainly caused by the mange mite Psoroptes ovis, which can infect horses, sheep, buffaloes, rabbits, other domestic animals, deer, wild camels, foxes, minks, lemurs, alpacas, elks and other wild animals. Features of the disease include intense pruritus and dermatitis, depilation and hyperkeratosis, which ultimately result in emaciation or death caused by secondary bacterial infections. The infestation is usually transmitted by close contact between animals...
November 4, 2016: Parasites & Vectors
https://www.readbyqxmd.com/read/27807761/oral-lichen-sclerosus-a-rare-case-report-and-review-of-the-literature
#15
Helvécio Marangon Júnior, Paulo Eduardo Alencar Souza, Rodrigo Villamarim Soares, Ricardo Santiago Gomez, Gustavo Henrique de Mattos Pereira, Martinho Campolina Rebello Horta
Lichen sclerosus (LS) is a chronic inflammatory mucocutaneous disease that often affects the anogenital area and causes significant discomfort and morbidity. Oral mucosal lesions in LS are extremely rare and might be associated with genital and/or skin manifestations. As a unique manifestation of LS, oral lesions are even more rare, with only 20 cases reported in English-language literature. In reviewing that literature in this paper, we present the case of a 44-year-old white man who sought dental assistance with a complaint of a white spot on his upper lip...
November 2, 2016: Head and Neck Pathology
https://www.readbyqxmd.com/read/27789051/-multiple-epidermolytic-acanthomas-of-the-genitalia
#16
I Moulonguet, M Serre, D Herskovitch
BACKGROUND: Epidermolytic hyperkeratosis presents a particular histological image common to several clinical pictures, including that of keratinopathic ichthyoses. It may also occur fortuitously in various tumoral and inflammatory lesions. It is the elementary histopathological lesion of epidermolytic acanthoma, which may either be single or multiple, and when it occurs in the genital area, is known as epidermolytic hyperkeratosis of the genitalia or multiple epidermolytic acanthoma of the genitalia...
October 24, 2016: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/27786797/first-record-of-fibropapillomatosis-in-a-green-turtle-chelonia-mydas-from-the-baja-california-peninsula
#17
Eduardo Reséndiz, Sergio Flores-Ramírez, Volker Koch, Amaury Cordero-Tapia
Fibropapillomatosis (FP) is characterized by multiple fibroepithelial tumors in all parts of the skin and has been reported in sea turtles worldwide. Clinically infected individuals are often emaciated and anemic. In Mexico, however, there are few records of this disease. In this study of green turtles Chelonia mydas in Laguna San Ignacio in Baja California Sur (BCS), we noted one juvenile with multifocal fibropapilloma lesions on the external upper surface of its eyes and hind flippers. Light microscopy revealed hyperkeratosis, epidermal hyperplasia, dermal papillary projections, and fibroblast proliferation...
December 2016: Journal of Aquatic Animal Health
https://www.readbyqxmd.com/read/27778402/multiple-minute-digitate-hyperkeratosis-in-an-infant
#18
Felicidade Santiago, Katarina Kieselova, Gustavo Januário, Martinha Henrique
A distinct variant of multiple minute digitate hyperkeratoses in a healthy 4-month-old boy, exclusively located in the anogenital area and with a transitory character, is described.
October 25, 2016: Pediatric Dermatology
https://www.readbyqxmd.com/read/27769847/incomplete-klk7-secretion-and-upregulated-lekti-expression-underlie-hyperkeratotic-stratum-corneum-in-atopic-dermatitis
#19
Satomi Igawa, Mari Kishibe, Masako Minami-Hori, Masaru Honma, Hisashi Tsujimura, Junko Ishikawa, Tsutomu Fujimura, Masamoto Murakami, Akemi Ishida-Yamamoto
Atopic dermatitis (AD) is a common inflammatory skin disorder. Chronic AD lesions present hyperkeratosis, indicating a disturbed desquamation process. Kallikrein-related peptidase (KLK) 7 is a serine protease involved in the proteolysis of extracellular corneodesmosome (CD) components, including desmocollin1 and corneodesmosin (Cdsn), which leads to desquamation. KLK7 is secreted by lamellar granules, and upregulated in AD lesional skin. However, despite increased KLK7 protein levels, immunostaining and electron microscopy indicated numerous CDs remaining in the uppermost layer of the stratum corneum (SC) from AD lesions...
October 18, 2016: Journal of Investigative Dermatology
https://www.readbyqxmd.com/read/27736001/human-papillomaviruses-genotyping-in-plantar-warts
#20
Elena de Planell-Mas, Blanca Martínez-Garriga, Antonio Jesús Zalacain, Teresa Vinuesa, Miguel Viñas
INTRODUCTION: Plantar warts are caused by human papillomaviruses (HPVs) and have been associated with several HPV genotypes. However, there are few studies focused exclusively on plantar warts. In this work, we aim to identify the HPV genotypes of plantar warts and explore their relation to demographic and clinical characteristics of patients. MATERIAL AND METHODS: A total of 72 patients diagnosed with plantar warts were recruited at the Laser unit at Podiatric Hospital, University of Barcelona, Spain...
October 13, 2016: Journal of Medical Virology
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