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corneoscleral graft

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https://www.readbyqxmd.com/read/28971253/-block-excision-with-tectonic-corneoscleral-graft-for-traumatic-pediatric-epithelial-implantation-cysts
#1
G Avgitidou, L M Heindl, C Cursiefen
Invasion of corneal epithelium into the anterior chamber can arise after ocular surgery or penetrating injury. This is extremly rare with an incidence of 0-0.2%. Three different types can be distiguished: cystic, diffuse and mixed form. Only cystic epithelial invasion can be treated with a curative therapeutic option that is blockexzision with tectonic corneoscleral transplantation.
September 29, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/28924441/primary-corneoscleral-cyst-in-a-pediatric-patient
#2
Charudutt Kalamkar, Amrita Mukherjee
PURPOSE: Primary corneoscleral cyst is a rare disease occurring in the pediatric age group. We report a case of corneoscleral cyst with visual diminution. METHODS: We conducted a case report. RESULTS: A 7-year-old girl presented with corneal opacity in the left eye. Examination revealed a corneoscleral cyst. The corneal part of the cyst involved visual axis. Surgical excision with a scleral graft was performed, leading to an improvement in visual acuity...
May 2017: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/28902013/-bubble-in-the-roll-technique-using-the-endoject-dmek-injector-influence-of-the-air-bubble-on-endothelial-cell-loss
#3
Yasemin Akbaba, Julia M Weller, Kathrin Rössler, W John Armitage, Ursula Schlötzer-Schrehardt, Friedrich E Kruse, Theofilos Tourtas
PURPOSE: To evaluate the impact of the air bubble on endothelial cell loss using the "bubble-in-the-roll" technique during Descemet membrane endothelial keratoplasty (DMEK). METHODS: Twenty DMEK grafts not suitable for transplantation were manually prepared from organ-cultured corneoscleral discs and injected into culture media using the Endoject DMEK injector (Medicel AG, Wolfhalden, Switzerland). Based on the injection method, the grafts were divided into 2 groups: In group A (n = 10), a small air bubble was placed inside the graft roll while it was in the injector...
December 2017: Cornea
https://www.readbyqxmd.com/read/28900769/interface-scopulariopsis-gracilis-fungal-keratitis-following-descemet-s-stripping-automated-endothelial-keratoplasty-dsaek-with-a-contaminated-graft
#4
Craig Wilde, Marco Messina, Tara Moshiri, Susan E Snape, Senthil Maharajan
PURPOSE: To report for the first time a case of interface Scopulariopsis gracilis fungal keratitis following Descemet's stripping automated endothelial keratoplasty (DSAEK) with a contaminated graft. METHODS: A 57-year-old man with bilateral keratoconus and previous bilateral penetrating keratoplasties (PK) developed graft failure in association with marked corneal ectasia. He underwent a successful DSAEK. Unfortunately, a contaminated graft was transplanted and the following morning we were contacted by the eye bank to inform us a slow-growing fungus had been detected in the culture plates inoculated with dextran solution used to store the issued corneoscleral button...
September 12, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28690536/catastrophic-thermal-corneoscleral-injury-treated-with-transplantation-of-donor-scleral-graft
#5
Satoru Kase, Takeshi Ohguchi, Susumu Ishida
BACKGROUND: The aim of this study is to report a patient with senile cataract developing severe thermal corneoscleral injury during phacoemulsification, which was treated with a donor scleral graft. CASE: Severe thermal corneoscleral injury occurred during phacoemulsification in the right eye of a 74-year-old male. His medical history was prostate hypertrophy. Visual acuity was hand motion and the intraocular pressure was 3 mm Hg OD. There was heavy corneal stromal opacity with intraocular fluid leakage...
May 2017: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/28574133/technical-feasibility-of-isolated-bowman-layer-graft-preparation-by-femtosecond-laser-a-pilot-study
#6
Jack S Parker, Forest Huls, Elizabeth Cooper, Paul Graves, Esther A Groeneveld-van Beek, Jessica Lie, Gerrit R J Melles
PURPOSE: To evaluate the technical feasibility of isolated Bowman layer (BL) graft preparation by femtosecond laser (FSL) and to compare the ultrastructural morphology to manually dissected grafts. METHODS: Five whole globes were placed in custom-made eye holders and debrided of epithelium. After programming a dissection depth of 20 μm, the FSL was docked into position and 5 isolated BL grafts were created. From 5 additional globes, corneoscleral buttons were procured, mounted in artificial anterior chambers, and stripped of BL via the previously described manual technique...
May 26, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28567165/letter-to-the-editor-corneoscleral-melt-50-years-after-excision-of-pterygium
#7
Aki Kondo, Tatsuya Mimura, Mari Goto, Yuko Kamei, Saito Yusuke, Hiroko Okuma, Masao Matsubara
PURPOSE: To report a case of corneoscleral melt that occurred 50 years after resection of pterygium with postoperative administration of mitomycin C (MMC). RESULTS: A 93-year-old woman developed acute corneal perforation and scleral melt in her left eye at 50 years after pterygium surgery with postoperative topical MMC. She underwent limbal transplantation. The anterior chamber reformed postoperatively and her intraocular pressure was normal. At 12 months after transplantation, best-corrected visual acuity was 20/500 and the graft-host junction was well apposed...
2017: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/28559840/limbal-stem-cell-sparing-corneoscleroplasty-with-peripheral-intralamellar-tuck-a-new-surgical-technique-for-keratoglobus
#8
Elias Jarade, Rafic Antonios, Sylvain El-Khoury
PURPOSE: To describe the technique of limbal stem cell-sparing corneoscleroplasty for the management of advanced keratoglobus. METHODS: A patient with bilateral advanced keratoglobus, with best-corrected visual acuity of 20/400 in the right eye and 20/200 in the left eye, underwent limbal stem cell-sparing corneoscleroplasty of the right eye. Initially, a 360-degree limbal incision with 200-μm depth was created, followed by a sublimbal tunnel dissection into the sclera, in order to conserve stem cells...
January 2017: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/28544131/sclerocorneal-graft-and-sequential-removal-of-melted-cornea-after-severe-corneal-burn-with-perforation
#9
Anja Viestenz, Berthold Seitz, Hans-Gert Struck, Arne Viestenz
INTRODUCTION: Corneal burn grade IV usually leads to blindness. Several different surgical techniques remain challenging owing to the extensive tissue damage. Here, we introduce a novel technique with a 15 mm corneoscleral and limbal homologous graft combined with sequential autologous corneal removal ab interno, with a vitrectomy probe to save the anterior chamber angle. In vivo anatomy with optical coherence tomography is the surgical key. METHOD: A large 15 mm sclerocorneal graft is sutured on top of the remainder of the destroyed cornea and sclera after removal of the epithelium and conjunctiva, with anterior synechiolysis if necessary, peripheral iridectomy and conjunctivoplasty...
May 22, 2017: Clinical Anatomy
https://www.readbyqxmd.com/read/28386160/a%C3%A2-serious-adverse-surgical-event-management-of-suspected-hsv-1-keratitis-in-a%C3%A2-donor-cornea
#10
Rebecca Kaye, Bernhard Steger, Jern Y Chen, Vito Romano
PURPOSE: To describe the management of a serious adverse event in a patient undergoing penetrating keratoplasty (PK). CASE REPORT: A 68-year-old man underwent PK for an aphakic bullous keratopathy following previous complicated cataract surgery. He had no past history of herpetic disease. Storage of the corneoscleral disc in the transport bottle precluded microscopic examination. After placement of the trephined donor cornea on the open eye of the recipient, a large dendritiform geographic ulcer was noted on the donor cornea...
2017: Spektrum der Augenheilkunde: Zeitschrift der Österreichischen Ophthalmologischen Gesellschaft, ÖOG
https://www.readbyqxmd.com/read/28379858/keratolimbal-allograft
#11
REVIEW
Albert Y Cheung, Edward J Holland
PURPOSE OF REVIEW: Keratolimbal allograft (KLAL) transplants limbal tissue attached to a corneoscleral carrier from a cadaveric donor to deliver a large number of stem cells to the recipient. The present article will provide a review of KLAL focusing on the recent literature. RECENT FINDINGS: Recent findings pertain to tissue selection, immunosuppression and adverse event profiles, and postoperative complications (particularly related to immunologic rejection). SUMMARY: KLAL permits the treatment of limbal stem cell deficiency eyes when there is no available living-related or autograft tissue with minimal risk of irreversible toxicity from modern systemic immunosuppression...
July 2017: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/28326192/differences-in-surgical-management-of-corneal-perforations-measured-over-six-years
#12
Katarzyna Krysik, Dariusz Dobrowolski, Anita Lyssek-Boron, Judyta Jankowska-Szmul, Edward A Wylegala
Purpose. To report the surgical approach, anatomical and functional results, and complications in the group of patients with corneal perforation. Materials and Methods. 247 eyes with corneal perforation were operated on between January 2010 and July 2016. The three surgical procedures, dependent on size and location of perforation, were performed: full-sized penetrating keratoplasty, corneoscleral patch graft, and anterior lamellar keratoplasty. The eyes underwent the minimum 6-month follow-up visit. Results...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28255771/amniotic-membrane-in-ophthalmology-properties-preparation-storage-and-indications-for-grafting-a-review
#13
REVIEW
Katerina Jirsova, Gary L A Jones
The use of amniotic membrane in ophthalmic surgery and other surgical procedures in the fields of dermatology, plastic surgery, genitourinary medicine and otolaryngology is on the increase. Furthermore, amniotic membrane and its epithelial and mesenchymal cells have broad use in regenerative medicine and hold great promise in anticancer treatment. Amniotic membrane is a rich source of biologically active factors and as such, promotes healing and acts as an effective material for wound dressing. Amniotic membrane supports epithelialization and exhibits anti-fibrotic, anti-inflammatory, anti-angiogenic and anti-microbial features...
June 2017: Cell and Tissue Banking
https://www.readbyqxmd.com/read/27974291/organ-cultured-prestripped-donor-tissue-for-dmek-surgery-clinical-outcomes
#14
Johannes Menzel-Severing, Friedrich E Kruse, Theofilos Tourtas
AIM: To determine whether clinical performance is negatively affected by prestripping Descemet membrane endothelial keratoplasty (DMEK) grafts from organ-cultured corneas. METHODS: We reviewed clinical records of all patients who underwent DMEK surgery for Fuchs endothelial dystrophy between 28 October 2014 and 11 August 2015. Grafts had been prepared from organ-cultured corneoscleral buttons 24 hours prior to surgery or during surgery. We included only patients for which at least one follow-up examination was available at a minimum of 2 months postoperatively...
August 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/27938949/dual-purpose-corneal-tissue-for-anterior-lamellar-keratoplasty-and-descemet-s-membrane-endothelial-keratoplasty
#15
C Larena Menant-Tay, Ronan Conlon, Salina Teja, Season Yeung, Joshua Teichman, Setareh Ziai, Kashif Baig
OBJECTIVE: To assess the intraoperative issues and surgical outcomes of preparing a single-donor corneal tissue for same-day use in both deep anterior lamellar keratoplasty (DALK) and Descemet's membrane endothelial keratoplasty (DMEK). DESIGN: Consecutive retrospective case series. PARTICIPANTS: Ten eyes of 10 patients who underwent DALK (5 patients) or DMEK (5 patients) surgery using dual-purpose corneal tissue. METHODS: Five dual-purpose corneoscleral rims were used to prepare tissue for 5 DMEK and 5 DALK procedures...
December 2016: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/27858161/two-photon-optical-microscopy-imaging-of-endothelial-keratoplasty-grafts
#16
Marco Lombardo, Mohit Parekh, Sebastiano Serrao, Alessandro Ruzza, Stefano Ferrari, Giuseppe Lombardo
PURPOSE: To investigate the microstructure of endothelial keratoplasty grafts using two-photon optical microscopy. METHODS: Six endothelial keratoplasty grafts obtained from human donor corneoscleral tissues and prepared by submerged hydrodissection technique were imaged by two-photon optical microscopy. In each graft, two liquid bubbles were created in order to investigate the presence of a conserved cleavage plane regardless of the volume of posterior stroma that remained attached to Descemet's membrane (DM); the first bubble (bubble A) was generated under DM and the second bubble (bubble B) injection was done in order to obtain a layer of deep stroma that kept the two bubbles separated...
March 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/27817919/incidence-and-outcomes-of-positive-donor-corneoscleral-rim-fungal-cultures-after-keratoplasty
#17
Jesse M Vislisel, Kenneth M Goins, Michael D Wagoner, Gregory A Schmidt, Benjamin T Aldrich, Jessica M Skeie, Cynthia R Reed, M Bridget Zimmerman, Mark A Greiner
PURPOSE: To determine the incidence of positive corneoscleral donor rim fungal cultures after keratoplasty and to report clinical outcomes of grafts with culture-positive donor rims. DESIGN: Retrospective cohort study. PARTICIPANTS: Consecutive donor corneas and keratoplasty recipients at a single tertiary referral center over 20 years. METHODS: Patient charts were reviewed to determine the incidence of positive donor rim fungal cultures and clinical outcomes of all grafts using contaminated tissue...
January 2017: Ophthalmology
https://www.readbyqxmd.com/read/27617872/sex-chromosome-analysis-of-postmortem-corneal-endothelium-after-sex-mismatch-descemet-membrane-endothelial-keratoplasty
#18
Itay Lavy, Robert M Verdijk, Marieke Bruinsma, Hein F Sleddens, Silke Oellerich, Perry S Binder, Gerrit R J Melles
PURPOSE: To identify the origin of corneal endothelial cells (host or donor) present on grafts at various time points after Descemet membrane endothelial keratoplasty (DMEK), using fluorescence in situ hybridization (FISH) of sex chromosomes on post mortem corneas with sex mismatch between the donor and host. METHODS: Corneoscleral buttons of 6 post mortem DMEK eyes of 4 patients, operated for Fuchs endothelial dystrophy, with an average postoperative time of 2...
January 2017: Cornea
https://www.readbyqxmd.com/read/27617870/surgical-management-of-limbal-dermoids-using-anterior-corneal-buttons-from-descemet-stripping-automated-endothelial-keratoplasty-donor-tissue-as-patch-grafts
#19
Kuan-I Wu, Hsiao-Sang Chu, Amy Shih-I Pai, Yu-Chih Hou, Szu-Yuan Lin, Wei-Li Chen, Fung-Rong Hu
PURPOSE: To assess the surgical and clinical outcomes of anterior lamellar keratoplasty using anterior corneal buttons from Descemet stripping automated endothelial keratoplasty (DSAEK) donor tissue. METHODS: Retrospective data from 8 patients with unilateral limbal dermoids, treated between February 2011 and January 2016 at National Taiwan University Hospital, were analyzed. Donor corneas for DSAEK were divided into anterior and posterior lamellae using a 350-μm microkeratome...
January 2017: Cornea
https://www.readbyqxmd.com/read/27362885/donor-tissue-preparation-for-bowman-layer-transplantation
#20
COMPARATIVE STUDY
Esther A Groeneveld-van Beek, Jack Parker, Jessica T Lie, Vincent Bourgonje, Lisanne Ham, Korine van Dijk, Jacqueline van der Wees, Gerrit R J Melles
PURPOSE: To describe and compare 2 preparation techniques for Bowman layer (BL) grafts for use in BL transplantation. METHODS: A retrospective evaluation of the 2 methods for preparing BL grafts was performed, that is, BL graft preparation from donor globes not eligible for penetrating keratoplasty or endothelial keratoplasty (technique I, n = 36) and BL graft preparation from previously excised corneoscleral buttons (technique II, n = 36) that could not be used for PK or had been denuded of Descemet membrane and endothelium for Descemet membrane endothelial keratoplasty graft preparation...
December 2016: Cornea
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