Brian G Ballios, Maxwell Weisbrod, Clara C Chan, Armand Borovik, Jeffrey R Schiff, Kathryn J Tinckam, Atul Humar, S Joseph Kim, Edward H Cole, Allan R Slomovic
The objective of this study was to evaluate systemic immunosuppression regimens used for patients undergoing ocular surface stem cell transplantation, including their benefits and adverse effects in the adjunctive management of limbal stem cell deficiency (LSCD). A systematic literature review was conducted using the MEDLINE and EMBASE databases (1980-2015). Data were collected on surgical intervention(s), type of immunosuppressive agent(s), duration of immunosuppression, percentage with stable ocular surface at last follow-up, mean follow-up time, and demographics...
August 2018: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie