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Boston keratoprosthesis

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https://www.readbyqxmd.com/read/29676302/keratoprosthesis-current-global-scenario-and-a-broad-indian-perspective
#1
REVIEW
Geetha Iyer, Bhaskar Srinivasan, Shweta Agarwal, Deepti Talele, Ekta Rishi, Pukhraj Rishi, Sripriya Krishnamurthy, Lingam Vijaya, Nirmala Subramanian, Shanmugasundaram Somasundaram
Keratoprosthesis (Kpro) forms the last resort for bilateral end-stage corneal blindness. The Boston Type 1 and 2 Kpros, the modified osteo-odonto Kpro and the osteo-Kpro are the more frequently and commonly performed Kpros, and this review attempts to compile the current data available on these Kpros worldwide from large single-center studies and compare the indications and outcomes with Kpros in the Indian scenario. Although the indications have significantly expanded over the years and the complications have reduced with modifications in design and postoperative regimen, these are procedures that require an exclusive setup, and a commitment toward long-term follow-up and post-Kpro care...
May 2018: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29648915/response-to-modabber-and-harissi-dagher-s-letter-type-1-boston-keratoprosthesis-for-limbal-stem-cell-deficiency-in-epidermolysis-bullosa
#2
N Geetha Sravani, Ashik Mohamed, Virender S Sangwan
No abstract text is available yet for this article.
April 12, 2018: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/29643713/modified-conjunctival-flap-as-a-primary-procedure-for-nontraumatic-acute-corneal-perforation
#3
Yi-Chen Sun, Jason P Kam, Tueng T Shen
Objective: Appropriate management of nontraumatic acute corneal perforation is always a challenge even with the many advances in surgical materials and techniques. We reported the outcomes of a case series of acute corneal perforation repair using a newly modified conjunctival flap with amniotic membrane transplant (AMT), fibrin glue, and a bandage soft contact lens (BCL). Materials and Methods: A total of 13 consecutive referral cases with nontraumatic acute corneal perforation at the University of Washington were reviewed...
January 2018: Ci Ji Yi Xue za Zhi, Tzu-chi Medical Journal
https://www.readbyqxmd.com/read/29627599/improving-the-practicality-and-safety-of-artificial-corneas-pre-assembly-and-gamma-rays-sterilization-of-the-boston-keratoprosthesis
#4
Miguel Gonzalez-Andrades, Roholah Sharifi, Mohammad-Mirazul Islam, Thibaut Divoux, Michael Haist, Eleftherios Paschalis, Larisa Gelfand, Shamina Mamodaly, Luca Di Cecilia, Andrea Cruzat, Franz-Josef Ulm, James Chodosh, Francois Delori, Claes H Dohlman
PURPOSE: To make the Boston keratoprosthesis (B-KPro), together with its carrier corneal graft, more easily procured, transported and stored, as well as less expensive, easier for the surgeon to implant and safer for the patient, it is proposed that the B-KPro-graft combination be pre-assembled by an expert technician, followed by sterilization with gamma ray irradiation (GI) allowing long-term storage at room temperature. For this to be possible, it must be shown that the B-KPro itself (not only the graft) remains unharmed by the irradiation...
April 5, 2018: Ocular Surface
https://www.readbyqxmd.com/read/29597010/boston-keratoprosthesis-type-1-for-limbal-stem-cell-deficiency-after-severe-chemical-corneal-injury-a-systematic-review
#5
REVIEW
Swapna S Shanbhag, Hajirah N Saeed, Eleftherios I Paschalis, James Chodosh
PURPOSE: To systematically review the published literature on outcomes of Boston keratoprosthesis type 1 for the treatment of limbal stem cell deficiency secondary to severe chemical corneal injury. METHODS: Literature searches were conducted in MEDLINE (Ovid), Embase, Web of Science, and the Cochrane Central Register. The main outcome measures assessed were the proportion of eyes with best-corrected visual acuity (BCVA) ≥ 20/200 and the proportion retaining their original keratoprosthesis, both at the last recorded visit...
March 26, 2018: Ocular Surface
https://www.readbyqxmd.com/read/29563700/fungal-keratitis-and-endophthalmitis-after-implantation-of-type-1-keratoprosthesis
#6
Chintan Malhotra, Arun Kumar Jain, Nikhil Aggarwal
A 70-year-old patient who underwent uneventful primary implantation of Auro K Pro (a Type I Boston Keratoprosthesis-based device), developed infiltrates in the deep stroma of the carrier corneal graft and exudates on the optic stem of the keratoprosthesis assembly, 6 weeks postoperatively, which subsequently progressed to endophthalmitis. Vitreous tap was positive for a panfungal polymerase chain reaction, although corneal scrapings for both Gram stain and KOH wet mount yielded negative results. Aggressive management with systemic, topical, intravitreal, and intrastromal antifungal agents resulted in an initial resolution, but residual inflammatory vitreous membranes persisted...
January 2018: Oman Journal of Ophthalmology
https://www.readbyqxmd.com/read/29543561/letter-to-the-editor-type-1-boston-keratoprosthesis-for-limbal-stem-cell-deficiency-in-epidermolysis-bullosa
#7
Milad Modabber, Mona Harissi-Dagher
No abstract text is available yet for this article.
March 15, 2018: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/29538593/anterior-segment-optical-coherence-tomography-findings-in-type-i-boston-keratoprosthesis
#8
Luzia Diegues Silva, Albert Santos, Luciene Barbosa de Sousa, Norma Allemann, Lauro Augusto de Oliveira
PURPOSE: To report the results of high-resolution anterior segment optical coherence tomography of patients implanted with a type 1 Boston keratoprosthesis (KPro). METHODS: The retrospective study cohort included 11 eyes of 11 patients (average age, 58.4 years; range, 34-83 years). All subjects underwent anterior segment optical coherence tomography at a single posteoperative time point. The main outcome measures were retro-backplate and retro-optic membrane formation, thinning and gap formation of the corneal carrier graft (melting), and degree of angle closure...
January 2018: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/29521688/keratoprosthesis-decentration-and-tilt-results-in-degradation-in-image-quality
#9
Richard W Helms, Xiaowei Zhao, Rony R Sayegh
PURPOSE: To study the effect of decentration and tilt of the type I Boston keratoprosthesis (KPro) on image quality in both aphakic and pseudophakic eyes. METHODS: An optical ray-tracing program was used to simulate the image projected onto the retina in an eye with a perfectly centered KPro, and in eyes with varying degrees of KPro decentration and tilt. Decentration was modeled along a typical white-to-white distance of 12.0 mm, and the corresponding tilt was calculated assuming a radius of curvature of 8...
March 6, 2018: Cornea
https://www.readbyqxmd.com/read/29497273/long-term-outcomes-of-the-aphakic-snap-on-boston-type-i-keratoprosthesis-at-the-bascom-palmer-eye-institute
#10
Allister Gibbons, Ella H Leung, Luis J Haddock, Carlos A Medina, Viviana Fernandez, Jean-Marie A Parel, Heather A Durkee, Guillermo Amescua, Eduardo C Alfonso, Victor L Perez
Purpose: To determine the indications, long-term clinical and visual outcomes, and complications of the aphakic snap-on type I Boston keratoprosthesis (KPro). Design: Retrospective, non-comparative case series. Methods: Forty-five eyes of 43 patients with type I aphakic snap-on KPros with at least 1 year of follow-up were included. The past medical histories, preoperative indications, best-corrected visual acuities (BCVAs), postoperative complications, and retention rates were analyzed...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29474297/recognition-of-fungal-keratitis-in-boston-type-i-keratoprosthesis-importance-of-awareness-and-novel-identification-of-exophiala-phaeomuriformis
#11
Lindsay Machen, Felix Y Chau, Jose de la Cruz, Joel Sugar, Maria Soledad Cortina
PURPOSE: To present a case of Exophiala phaeomuriformis fungal keratitis to demonstrate the heightened concern for fungal infection in patients with a keratoprosthesis and to highlight the rare involvement of Exophiala phaeomuriformis. METHODS: Case report. RESULTS: Exophiala phaeomuriformis was identified in a susceptible patient 7 years after Boston type I keratoprosthesis (KPro) implantation. CONCLUSIONS: Although fungal infiltration after KPro placement does not represent a novel clinical infection, identification of the rare Exophiala species in a patient with a KPro has not been reported and provides an opportunity for reflection on fungal identification, prophylaxis, and prevention in this vulnerable patient population...
February 22, 2018: Cornea
https://www.readbyqxmd.com/read/29474296/assessment-of-glaucomatous-damage-after-boston-keratoprosthesis-implantation-based-on-digital-planimetric-quantification-of-visual-fields-and-optic-nerve-head-imaging
#12
Mohsin H Ali, Mark S Dikopf, Anthony G Finder, Ahmad A Aref, Thasarat Vajaranant, Jose de la Cruz, Maria Soledad Cortina
PURPOSE: To investigate glaucomatous damage in Boston keratoprosthesis type I (KPro) patients through structural analysis of the optic nerve head and digital planimetric quantification of Goldmann visual fields, a novel method of monitoring perimetric changes in KPro patients. METHODS: Records of patients undergoing KPro implantation from 2007 to 2015 at a single institution were reviewed. Parameters related to glaucoma status and KPro outcomes were analyzed. RESULTS: Twenty-two eyes from 21 patients met inclusion criteria, with mean follow-up of 49...
May 2018: Cornea
https://www.readbyqxmd.com/read/29440740/boston-keratoprosthesis-type-1-outcomes-of-the-first-38-cases-performed-at-moorfields-eye-hospital
#13
Chameen Samarawickrama, Nicholas Strouthidis, Mark R Wilkins
PURPOSE: To evaluate outcomes of Boston keratoprosthesis type 1 (K-Pro) surgery in a cohort of high-risk patients at Moorfields Eye Hospital. Our patients were referred to us at the end-point of their ocular disease. METHODS: A retrospective review of all K-Pro surgery performed between March 2011 and July 2015 with a minimum follow-up of 12 months. RESULTS: 39 eyes of 38 patients were included. Mean follow-up was 28.4 months (range: 12-56)...
February 14, 2018: Eye
https://www.readbyqxmd.com/read/29408907/five-year-outcomes-of-boston-type-i-keratoprosthesis-as-primary-versus-secondary-penetrating-corneal-procedure-in-a-matched-case-control-study
#14
Kai B Kang, Faris I Karas, Ruju Rai, Joelle A Hallak, Joann J Kang, Jose de la Cruz, Maria S Cortina
Despite improved retention and reduced complication rates paving the way for the current expansion of applications and surge in prevalence for the Boston type I Keratoprosthesis (KPro), the most frequent indication for its implantation today remains prior graft failure. The purpose of this study is to evaluate the long-term outcomes of primary KPro and compare to secondary implantation in a matched cohort study. This study included patients who underwent KPro implantation in a single center by two surgeons between July 2008 and October 2014...
2018: PloS One
https://www.readbyqxmd.com/read/29390260/paraproteinemic-keratopathy-in-monoclonal-gammopathy-of-undetermined-significance-treated-with-primary-keratoprosthesis-case-report-histopathologic-findings-and-world-literature-review
#15
Homer H Chiang, Rebekah S Wieland, Thomas S Rogers, Pamela C Gibson, George Atweh, Gregory McCormick
RATIONALE: We report a case of paraproteinemic keratopathy associated with monoclonal gammopathy of undetermined significance, treated with keratoprosthesis as a primary penetrating procedure. Histopathological findings and a world literature review are presented. PATIENT CONCERNS: A 74 year old female recently diagnosed with monoclonal gammopathy undetermined significance presented with progressive blurry vision bilaterally. DIAGNOSES: Examination revealed corneal opacities consistent with paraproteinemic keratopathy...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29370031/comparison-of-visual-and-anatomical-outcomes-of-eyes-undergoing-type-i-boston-keratoprosthesis-with-combination-pars-plana-vitrectomy-with-eyes-without-combination-vitrectomy
#16
Jennifer I Lim, Lindsay Machen, Andrea Arteaga, Faris I Karas, Robert Hyde, Dingcai Cao, Marcia Niec, Thasarat S Vajaranant, M Soledad Cortina
PURPOSE: To determine whether 1-year visual and anatomical results after surgery combining pars plana vitrectomy, Boston keratoprosthesis, and a glaucoma drainage device as needed are similar, better, or worse than Boston keratoprosthesis initial implantation alone. METHODS: We performed a retrospective review of adult patients undergoing Boston keratoprosthesis at our institution. Visual acuity outcomes, anatomical results, and complication rates of patients undergoing combination surgery (including pars plana vitrectomy and a posterior glaucoma drainage device) were compared with those undergoing keratoprosthesis placement alone...
January 23, 2018: Retina
https://www.readbyqxmd.com/read/29260063/results-with-the-boston-type-i-keratoprosthesis-after-acanthamoeba-keratitis
#17
Albert Santos, Luzia Diegues Silva, Luciene Barbosa de Sousa, Denise de Freitas, Lauro Augusto de Oliveira
Purpose: To report the outcomes of implantation of the Boston Type I keratoprosthesis in three patients with Acanthamoeba keratitis (AK), a severe infection that can lead to significant visual loss. Observations: Case series reporting three patients with difficult cases of AK that needed multiple corneal transplantations and glaucoma surgeries. All patients were implanted with the Boston Type I keratoprosthesis device. The main outcomes measure were the visual function and anatomical retention after implantation of the Boston Type I keratoprosthesis...
June 2017: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29219955/-on-the-capability-and-nomenclature-of-the-boston-keratoprosthesis-type-ii
#18
M Zarei-Ghanavati, A Shalaby Bardan, C Liu
No abstract text is available yet for this article.
January 2018: Eye
https://www.readbyqxmd.com/read/29219899/clinical-outcomes-using-oversized-back-plates-in-type-i-boston-keratoprosthesis
#19
Aaron R Kaufman, Andrea Cruzat, Kathryn A Colby
OBJECTIVES: To examine clinical outcomes of oversized titanium back plates in type I Boston keratoprosthesis (KPro) implantation. METHODS: Retrospective study of 22 sequential eyes (20 patients) undergoing type I KPro implantation with an oversized titanium back plate (larger than trephined wound diameter by 1.0 mm or more), performed by a single surgeon (K.A.C.) from June 2010 to November 2014. Data were collected regarding preoperative eye characteristics, surgical details, and postoperative clinical outcomes...
December 5, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/29140862/retroprosthetic-membrane-formation-in-boston-keratoprosthesis-a-case-control-matched-comparison-of-titanium-versus-pmma-backplate
#20
Rushi K Talati, Joelle A Hallak, Faris I Karas, Jose de la Cruz, M Soledad Cortina
PURPOSE: Retroprosthetic membrane (RPM) formation is the most common complication after Boston type 1 keratoprosthesis (KPro) implantation. It affects visual acuity and can predispose to corneal melt. Two KPro backplate materials are available: titanium and polymethyl methacrylate (PMMA). This study investigates the influence of the KPro backplate material on visually significant RPM formation. METHODS: A retrospective case-control-matched study involving 40 patients; 20 eyes implanted with a titanium backplate KPro were case-matched with 20 eyes implanted with a PMMA backplate KPro between 2007 and 2015 with 1-year minimum follow-up...
February 2018: Cornea
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