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https://www.readbyqxmd.com/read/28815800/a-method-for-data-driven-exploration-to-pinpoint-key-features-in-medical-data-and-facilitate-expert-review
#1
Kristina Juhlin, Kristina Star, G Niklas Norén
PURPOSE: To develop a method for data-driven exploration in pharmacovigilance and illustrate its use by identifying the key features of individual case safety reports related to medication errors. METHODS: We propose vigiPoint, a method that contrasts the relative frequency of covariate values in a data subset of interest to those within one or more comparators, utilizing odds ratios with adaptive statistical shrinkage. Nested analyses identify higher order patterns, and permutation analysis is employed to protect against chance findings...
August 16, 2017: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/28801002/legal-support-for-palliative-care-patients
#2
Tamar Ezer, Naomi Burke-Shyne, Kiera Hepford
CONTEXT: Palliative care patients face legal issues which impact their quality of life. Legal support, embedded in holistic palliative care services, has developed globally over the last decade to address this. OBJECTIVES: This paper aims to trace the origins of legal support for palliative care patients, detail models of legal support, and describe achievements and challenges. METHODS: The paper draws on years of work in this area, as well as the available literature...
August 8, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28796535/delay-discounting-and-probability-discounting-but-not-response-inhibition-are-associated-with-sexual-risk-taking-in-adults
#3
Steven R Lawyer, Colin T Mahoney
Sexual risk behavior (SRB) is associated with impulsivity, but it is not clear whether different aspects of impulsivity are uniquely related to SRBs in adults. Unmarried adults ages 18 to 30 (N = 296; 41.0% male) recruited from the community reported their frequency of SRBs over the past six months using the Sexual Risk Survey (SRS; Turchik & Garske, 2009) and completed three behavioral measures of impulsivity: insensitivity to delayed consequences (delay discounting [DD]), insensitivity to probabilistic consequences (probability discounting [PD]) and response inhibition (stop signal task [SST])...
August 10, 2017: Journal of Sex Research
https://www.readbyqxmd.com/read/28795892/cold-atmospheric-pressure-plasma-for-treatment-of-chronic-wounds-drug-or-medical-device
#4
A Kramer, B R Conway, K Meissner, F Scholz, B H Rauch, A Moroder, A Ehlers, A J Meixner, C-D Heidecke, L I Partecke, M Kietzmann, O Assadian
OBJECTIVE: The use of cold atmospheric pressure plasma (CAPP) as a new therapeutic option to aid the healing of chronic wounds appears promising. Currently, uncertainty exists regarding their classification as medical device or medical drug. Because the classification of CAPP has medical, legal, and economic consequences as well as implications for the level of preclinical and clinical testing, the correct classification is not an academic exercise, but an ethical need. METHOD: A multidisciplinary team of physicians, surgeons, pharmacists, physicists and lawyers has analysed the physical and technical characteristics as well as legal conditions of the biological action of CAPP...
August 2, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/28756785/impact-of-health-technology-assessment-in-litigation-concerning-access-to-high-cost-drugs
#5
Alicia Aleman, Ana Perez Galan
OBJECTIVES: The impact of health technology assessment (HTA) in the judicialization of the right of health has not been deeply studied in Latin American countries. The purpose of this study is to review the process of judicialization of the access to high cost drugs in Uruguay and assess the impact HTAs have had on this process. METHODS: The methodology used for this study included a comprehensive literature search in electronic databases, local journals, internal documents developed in the Ministry of Health, as well as conducting interviews with key informants...
July 31, 2017: International Journal of Technology Assessment in Health Care
https://www.readbyqxmd.com/read/28749484/communication-related-allegations-against-physicians-caring-for-premature-infants
#6
J Nguyen, H Muniraman, M Cascione, R Ramanathan
OBJECTIVE: Maternal-fetal medicine physicians (MFMp) and neonatal-perinatal medicine physicians (NPMp) caring for premature infants and their families are exposed to significant risk for malpractice actions. Effective communication practices have been implicated to decrease litigious intentions but the extent of miscommunication as a cause of legal action is essentially unknown in this population. Analysis of communication-related allegations (CRAs) may help toward improving patient care and physician-patient relationships as well as decrease litigation risks...
July 27, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/28730992/an-illustrated-guide-for-characters-and-terminology-used-in-descriptions-of-phlebotominae-diptera-psychodidae
#7
Eunice A B Galati, Fredy Galvis-Ovallos, Phillip Lawyer, Nicole Léger, Jérôme Depaquit
Phlebotomine (Diptera, Psychodidae, Phlebotominae) taxonomy has been studied extensively, primarily due to the role of these flies as vectors of various parasites, including species of Leishmania, Bartonella and arboviruses that cause diseases in humans and other vertebrates. We present some topics discussed at a round-table on phlebotomine taxonomy held at the Ninth International Symposium on Phlebotomine Sandflies (ISOPS IX) in Reims, France, in June 2016. To date, approximately one thousand phlebotomine species have been described worldwide, although in varying languages and mostly without standardization of characters and terminology...
2017: Parasite: Journal de la Société Française de Parasitologie
https://www.readbyqxmd.com/read/28724420/legal-access-to-medications-a-threat-to-brazil-s-public-health-system
#8
Ana Luiza Chieffi, Rita De Cassia Barata Barradas, Moisés Golbaum
BACKGROUND: In Brazil, health is fundamental human right guaranteed by the Constitution of 1988, which created the Brazilian Universal Health System (Sistema Único de Saúde - SUS). The SUS provides medications for outpatient care via policy of pharmaceutical assistance (PA) programmes. Despite the advances in PA policies which include the improvement in access to medications, there has been a significant increase in lawsuits related to health products and services. This study aimed to characterize the medication processes filed between 2010 and 2014 against the Secretary of State for Health of São Paulo (State Health Department of São Paulo - SES/SP), in Brazil, following PA policies...
July 19, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28681381/epilepsy-transition-from-pediatric-to-adult-care-recommendations-of-the-ontario-epilepsy-implementation-task-force
#9
REVIEW
Danielle M Andrade, Anne S Bassett, Eduard Bercovici, Felippe Borlot, Esther Bui, Peter Camfield, Guida Quaglia Clozza, Eyal Cohen, Timothy Gofine, Lisa Graves, Jon Greenaway, Beverly Guttman, Maya Guttman-Slater, Ayman Hassan, Megan Henze, Miriam Kaufman, Bernard Lawless, Hannah Lee, Lezlee Lindzon, Lysa Boissé Lomax, Mary Pat McAndrews, Dolly Menna-Dack, Berge A Minassian, Janice Mulligan, Rima Nabbout, Tracy Nejm, Mary Secco, Laurene Sellers, Michelle Shapiro, Marie Slegr, Rosie Smith, Peter Szatmari, Leeping Tao, Anastasia Vogt, Sharon Whiting, O Carter Snead
The transition from a pediatric to adult health care system is challenging for many youths with epilepsy and their families. Recently, the Ministry of Health and Long-Term Care of the Province of Ontario, Canada, created a transition working group (TWG) to develop recommendations for the transition process for patients with epilepsy in the Province of Ontario. Herein we present an executive summary of this work. The TWG was composed of a multidisciplinary group of pediatric and adult epileptologists, psychiatrists, and family doctors from academia and from the community; neurologists from the community; nurses and social workers from pediatric and adult epilepsy programs; adolescent medicine physician specialists; a team of physicians, nurses, and social workers dedicated to patients with complex care needs; a lawyer; an occupational therapist; representatives from community epilepsy agencies; patients with epilepsy; parents of patients with epilepsy and severe intellectual disability; and project managers...
July 6, 2017: Epilepsia
https://www.readbyqxmd.com/read/28661306/health-care-system-transformation-and-integration-a-call-to-action-for-public-health
#10
Lindsay F Wiley, Gene W Matthews
Restructured health care reimbursement systems and new requirements for nonprofit hospitals are transforming the U.S. health system, creating opportunities for enhanced integration of public health and health care goals. This article explores the role of public health practitioners and lawyers in this moment of transformation. We argue that the population perspective and structural strategies that characterize public health can add value to the health care system but could get lost in translation as changes to tax requirements and payment systems are rapidly implemented...
March 2017: Journal of Law, Medicine & Ethics: a Journal of the American Society of Law, Medicine & Ethics
https://www.readbyqxmd.com/read/28661289/immigration-and-health-law-policy-and-ethics
#11
Wendy E Parmet, Lorianne Sainsbury-Wong, Maya Prabhu
Immigration poses numerous challenges for health professionals and public health lawyers. This article reviews these challenges. We begin by offering some background on immigration and health and then explain some of the reasons why immigrants are less likely than natives to have health insurance. Next we turn to a discussion of some of the particular challenges relating to the health care of refugees. We conclude by analyzing and rejecting some of the arguments that are made for discriminating against immigrants with respect to the provision of public health benefits and services...
March 2017: Journal of Law, Medicine & Ethics: a Journal of the American Society of Law, Medicine & Ethics
https://www.readbyqxmd.com/read/28642509/in-our-opinion
#12
G Roberts, V S Lucas, F McDonald, S Camilleri, J Jayaraman, D Davies, K Moze
The misleading statements made in the British Dental Journal in the December 2016 issue relating to dental age assessment are assessed for inaccuracies and negligent omission of the issue of Child Protection. It is emphasised that there is a need for the approach of objective knowledge viz. not influenced by personal feelings or opinions in considering and representing facts. The article by the Chair of the Education, Ethics, and Team Working Group implies that unsatisfactory consent procedures are followed...
June 23, 2017: British Dental Journal
https://www.readbyqxmd.com/read/28638041/-the-presumption-of-mental-health-is-it-really-proved
#13
S N Shishkov, N V Skibina
The article is devoted to one of the most complicated and peculiar problems of modern psychiatry - the presumption of mental health. Its originality is seen in the fact that practically all speaking and writing about it noted the importance of this principle for the protection of rights and legal interests of citizens, failing into the field of psychiatry. However, expressing this opinion, doctors and lawyers offer very few arguments in support of this view. Traditional arguments in favor of the presumption of mental health, scattered and unsystematic, prove to be absolutely insolvent...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/28622536/peer-review-in-forensic-science
#14
REVIEW
Kaye N Ballantyne, Gary Edmond, Bryan Found
Peer review features prominently in the forensic sciences. Drawing on recent research and studies, this article examines different types of peer review, specifically: editorial peer review; peer review by the scientific community; technical and administrative review; and verification (and replication). The article reviews the different meanings of these quite disparate activities and their utility in relation to enhancing performance and reducing error. It explains how forensic practitioners should approach and use peer review, as well as how it should be described in expert reports and oral testimony...
May 25, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28585456/potential-conflicts-in-midwifery-practice-regarding-conscientious-objection-to-abortions-in-scotland
#15
Valerie Fleming, Yvonne Robb
BACKGROUND: This study was developed as a result of a court case involving conflicts between midwives' professional practice and their faith when caring for women undergoing abortions in Scotland. RESEARCH QUESTIONS: What are practising Roman Catholics' perspectives of potential conflicts between midwives' professional practice in Scotland with regard to involvement in abortions and their faith? How relevant is the 'conscience clause' to midwifery practice today? and What are participants' understandings of Canon 1398 in relation to midwifery practice? RESEARCH DESIGN: The theoretical underpinning of this study was Gadamer's hermeneutic out of which the method developed by Fleming et al...
January 1, 2017: Nursing Ethics
https://www.readbyqxmd.com/read/28582459/traumatic-injury-and-perceived-injustice-fault-attributions-matter-in-a-no-fault-compensation-state
#16
Liane J Ioannou, Peter A Cameron, Stephen J Gibson, Belinda J Gabbe, Jennie Ponsford, Paul A Jennings, Carolyn A Arnold, Stella M Gwini, Nellie Georgiou-Karistianis, Melita J Giummarra
BACKGROUND: Traumatic injury can lead to loss, suffering and feelings of injustice. Previous research has shown that perceived injustice is associated with poorer physical and mental wellbeing in persons with chronic pain. This study aimed to identify the relative association between injury, compensation and pain-related characteristics and perceived injustice 12-months after traumatic injury. METHODS: 433 participants were recruited from the Victorian Orthopedic Trauma Outcomes Registry and Victorian State Trauma Registry, and completed questionnaires at 12-14 months after injury as part of an observational cohort study...
2017: PloS One
https://www.readbyqxmd.com/read/28580630/the-midgut-microbiota-plays-an-essential-role-in-sand-fly-vector-competence-for-leishmania-major
#17
Isabelle Louradour, Carolina Cunha Monteiro, Ehud Inbar, Kashinath Ghosh, Richard Merkhofer, Phillip Lawyer, Andrea Paun, Margery Smelkinson, Nagila Secundino, Michael Lewis, Dinesh Erram, Ludek Zurek, David Sacks
For many arthropod vectors, the diverse bacteria and fungi that inhabit the gut can negatively impact pathogen colonization. Our attempts to exploit antibiotic treatment of colonized Phlebotomus duboscqi sand flies in order to improve their vector competency for Leishmania major resulted instead in flies that were refractory to the development of transmissible infections due to the inability of the parasite to survive and to colonize the anterior midgut with infective, metacyclic stage promastigotes. The parasite survival and development defect could be overcome by feeding the flies on different symbiont bacteria but not by feeding them on bacterial supernatants or replete medium...
June 5, 2017: Cellular Microbiology
https://www.readbyqxmd.com/read/28579819/outcomes-and-prognostic-variables-of-radiofrequency-zygapophyseal-joint-neurotomy-in-utah-workers-compensation-patients
#18
Tyler J Christensen, M Scott DeBerard, Anthony J Wheeler
PURPOSE: The prevalence of radiofrequency zygapophyseal joint neurotomy (RFN) has increased substantially across the past decade. Limited research exists that has examined pre-procedure predictors of RFN outcomes, particularly within workers' compensation populations. The purpose of this study was to determine if pre-procedure biopsychosocial variables are predictive of outcomes in a cohort of compensated Utah patients who have undergone RFN. PATIENTS AND METHODS: This was a retrospective cohort study consisting of a review of pre-procedure medical records and a telephone outcome survey...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28569707/know-how-in-postwar-business-and-law
#19
Douglas O'Reagan
In the mid-twentieth century, businesses around the world began to see technical know-how as one of the most important assets they could possess. While their exact definitions of know-how varied (usually centering on employees' tacit knowledge; accumulated, minor innovations rather than just patentable inventions; and tailoring to local conditions), the rapidly growing perception that it was invaluable led to widespread know-how licensing. As businesses embraced it, legal scholars and business lawyers during the 1950s through the 1970s scrambled to clarify legal bases for intellectual property protections for know-how...
2017: Technology and Culture
https://www.readbyqxmd.com/read/28559120/the-emerging-role-of-lawyers-as-addiction-quasi-experts
#20
Kate Seear
This paper examines a discrete set of issues pertaining to the constitution of addiction in law. Based on qualitative interviews undertaken with lawyers in Australia and Canada, I examine how addiction figures in lawyers' daily practice. Drawing on ideas from science and technology studies scholars Sheila Jasanoff, Michael Lynch and Bruno Latour, and building on recent research I undertook on legal addiction veridiction, I explore the constitution of addiction 'facts' in law. I examine how and when lawyers claim to make decisions about addiction in the course of their legal practice...
June 2017: International Journal on Drug Policy
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