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ocular response analyzer

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https://www.readbyqxmd.com/read/27893063/assessment-of-the-psychometric-properties-of-a-questionnaire-assessing-patient-reported-outcomes-with-laser-in-situ-keratomileusis-prowl
#1
Ron D Hays, Michelle E Tarver, Karen L Spritzer, Steve Reise, Gene Hilmantel, Elizabeth M Hofmeister, Keri Hammel, Jeanine May, Frederick Ferris, Malvina Eydelman
Importance: Patient-reported outcome (PRO) measures for laser in situ keratomileusis (LASIK) are needed. Objective: To develop PRO measures to assess satisfaction, eye-related symptoms, and their effect on functioning and well-being following LASIK based on patient and expert input. Design, Setting, and Participants: The Patient-Reported Outcomes With LASIK (PROWL) studies were prospective observational studies of patients undergoing LASIK surgery for myopia, hyperopia, or astigmatism...
November 23, 2016: JAMA Ophthalmology
https://www.readbyqxmd.com/read/27873338/high-myopes-have-lower-normalised-corneal-tangent-moduli-less-stiff-corneas-than-low-myopes
#2
Ying Hon, Guo-Zhen Chen, Shu-Hao Lu, David C C Lam, Andrew K C Lam
PURPOSE: To compare corneal tangent moduli between low and high myopes. METHODS: Corneal hysteresis (CH) and corneal resistance factor (CRF) of 32 low and 32 high myopes were obtained using an Ocular Response Analyzer, followed by a corneal indentation device that measured corneal stiffness. Corneal topography, pachymetry, Goldmann applanation tonometry intraocular pressure (GAT-IOP), and corneal compensated intraocular pressure (IOPcc) were also obtained. Corneal tangent modulus was calculated on the basis of corneal stiffness, central corneal thickness and corneal radius...
November 21, 2016: Ophthalmic & Physiological Optics: the Journal of the British College of Ophthalmic Opticians (Optometrists)
https://www.readbyqxmd.com/read/27863469/changes-in-intraocular-pressure-values-measured-with-noncontact-tonometer-nct-ocular-response-analyzer-ora-and-corvis-scheimpflug-technology-tonometer-cst-in-the-early-phase-after-small-incision-lenticule-extraction-smile
#3
Yang Shen, Xiangjian Su, Xiu Liu, Huamao Miao, Xuejun Fang, Xingtao Zhou
BACKGROUND: Corneal biomechanical properties are always compromised after corneal refractive surgeries thus leading to underestimated intraocular pressure (IOP) that complicates the management of IOP. We investigated the changes in postoperative baseline of IOP values measured with noncontact tonometer (NCT), ocular response analyzer (ORA) and corvis scheimpflug technology (CST) in the early phase after small incision lenticule extraction (SMILE). METHODS: Twenty-two eyes (-6...
November 18, 2016: BMC Ophthalmology
https://www.readbyqxmd.com/read/27847644/relationship-among-corneal-biomechanics-anterior-segment-parameters-and-geometric-corneal-parameters
#4
Sadık Görkem Çevik, Sertaç Argun Kıvanç, Berna Akova-Budak, Mediha Tok-Çevik
Purpose. To investigate the relationship between corneal biomechanical parameters, anterior segment parameters, and geometric corneal parameters in a healthy Caucasian group. Methods. This retrospective study included the healthy eyes with best corrected visual acuity of at least 20/40 of 122 Caucasian subjects. The anterior segment parameters and geometric corneal parameters such as corneal volume, central corneal thickness, horizontal and vertical corneal radii, anterior and posterior steep, and flat keratometric values were measured with a Scheimpflug camera...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27830201/corneal-biomechanics-after-small-incision-lenticule-extraction-versus-q-value-guided-femtosecond-laser-assisted-in-situ-keratomileusis
#5
Jun Zhang, Li Zheng, Xia Zhao, Yang Xu, Shu Chen
PURPOSE: The aim of this study was to compare the changes in corneal biomechanical properties following small-incision lenticule extraction (SMILE) versus Q-value-guided femtosecond laser-assisted in situ keratomileusis (Q-FS-LASIK). METHODS: In this prospective comparative study, patients with a sphere plus cylinder measurement of less than -10.00 D and cylinder measurement of less than -5.00 D were included in the study. A total of 160 patients (160 eyes) with myopia and myopic astigmatism were divided into the two groups, with 80 patients (80 eyes) allocated to SMILE and 80 patients (80 eyes) allocated to Q-FS-LASIK...
December 2016: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/27829990/analysis-of-the-effects-of-preservative-free-tafluprost-on-the-tear-proteome
#6
Sebastian Funke, Sabine Beck, Katrin Lorenz, Marion Kotterer, Dominik Wolters, Natarajan Perumal, Norbert Pfeiffer, Franz H Grus
The purpose of the present study was to assess the ocular surface health status in primary open angle glaucoma (POAG) patients switching from topical application of preserved latanoprost (LT) to preservative-free tafluprost (PFT) by tear proteomic monitoring. Tear fluid of POAG patients showing dry eye symptoms, using LT and switching to PFT as well as tear fluid of healthy controls has been examined. Tear proteome dynamics was monitored over 24 weeks in a first mass spectrometric explorative analysis in a small POAG patient cohort (N = 3)...
2016: American Journal of Translational Research
https://www.readbyqxmd.com/read/27829784/irbp-deficiency-permits-precocious-ocular-development-and-myopia
#7
Shanu Markand, Natecia L Baskin, Ranjay Chakraborty, Erica Landis, Sara A Wetzstein, Kevin J Donaldson, Priyanka Priyadarshani, Shannon E Alderson, Curran S Sidhu, Jeffrey H Boatright, P Michael Iuvone, Machelle T Pardue, John M Nickerson
PURPOSE: Interphotoreceptor retinoid-binding protein (IRBP) is abundant in the subretinal space and binds retinoids and lipophilic molecules. The expression of IRBP begins precociously early in mouse eye development. IRBP-deficient (KO) mice show less cell death in the inner retinal layers of the retina before eyelid opening compared to wild-type C57BL/6J (WT) controls and eventually develop profound myopia. Thus, IRBP may play a role in eye development before visually-driven phenomena...
2016: Molecular Vision
https://www.readbyqxmd.com/read/27826468/digital-analysis-of-eyelid-features-and-eyebrow-position-following-co2-laser-assisted-blepharoptosis-surgery
#8
Xiaodong Zheng, Hirohiko Kakizaki, Tomoko Goto, Atsushi Shiraishi
BACKGROUND: To compare the margin reflex distance of the upper (MRD-1) and lower (MRD-2) eyelids and the eyebrow height (EBH) in patients with involutional and hard contact lens wear--induced blepharoptosis before and after ptosis surgery. METHODS: Sixty patients with acquired blepharoptosis were studied. Group 1 consisted of 30 patients with involutional ptosis (age, 75.8 ± 6.4 years), and group 2 consisted of 30 patients with hard contact lens wear-induced ptosis (age, 50...
October 2016: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/27814360/mutation-in-lim2-is-responsible-for-autosomal-recessive-congenital-cataracts
#9
Bushra Irum, Shahid Y Khan, Muhammad Ali, Haiba Kaul, Firoz Kabir, Bushra Rauf, Fareeha Fatima, Raheela Nadeem, Arif O Khan, Saif Al Obaisi, Muhammad Asif Naeem, Idrees A Nasir, Shaheen N Khan, Tayyab Husnain, Sheikh Riazuddin, Javed Akram, Allen O Eghrari, S Amer Riazuddin
PURPOSE: To identify the molecular basis of non-syndromic autosomal recessive congenital cataracts (arCC) in a consanguineous family. METHODS: All family members participating in the study received a comprehensive ophthalmic examination to determine their ocular phenotype and contributed a blood sample, from which genomic DNA was extracted. Available medical records and interviews with the family were used to compile the medical history of the family. The symptomatic history of the individuals exhibiting cataracts was confirmed by slit-lamp biomicroscopy...
2016: PloS One
https://www.readbyqxmd.com/read/27803885/correlations-of-nasal-responses-to-leukotriene-d4-and-histamine-nasal-provocation-with-quality-of-life-in-allergic-rhinitis
#10
Zheng Zhu, Yanqing Xie, Weijie Guan, Yi Gao, Shu Xia, Xu Shi, Jinping Zheng
BACKGROUND: The symptoms of allergic rhinitis (AR) greatly affect the quality of life (QoL) in the patients with AR. The correlations of nasal response to leukotriene D4 (LTD4) and histamine nasal provocation with health related QoL in AR are not clear. OBJECTIVE: To evaluate the correlations of nasal response to LTD4 and histamine nasal challenge with QoL in AR. METHODS: Patients randomly underwent LTD4 and histamine nasal challenge tests, completed the rhinoconjunctivitis quality of life questionnaire (RQoLQ), and rating the symptom severity score (total symptom score 4, TSS4) in the previous week...
October 2016: Asia Pacific Allergy
https://www.readbyqxmd.com/read/27803856/effect-of-femtosecond-and-microkeratome-flaps-creation-on-the-cornea-biomechanics-during-laser-in-situ-keratomileusis-one-year-follow-up
#11
Qian Sun, Zheng-Zheng Deng, Yue-Hua Zhou, Jing Zhang, Xiao-Yan Peng
AIM: To compare the corneal biomechanical outcomes at one year after laser in situ keratomileusis (LASIK) with the flaps created by Ziemer and Moria M2 microkeratome with 110 head and -20 blade. METHODS: Totally 100 eyes of 50 consecutive patients were enrolled in this prospective study and divided into two groups for corneal flaps created by ZiemerFemto LDV and Moria M2 microkeratome with 110 head and -20 blade. Corneal biomechanical properties including cornea resistance factor (CRF) and cornea hysteresis (CH) were measured before and 1, 3, 6, 12mo after surgery by ocular response analyzer...
2016: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/27800259/comparison-of-changes-in-corneal-biomechanical-properties-after-photorefractive-keratectomy-and-small-incision-lenticule-extraction
#12
Yusuf Yıldırım, Onur Ölçücü, Abdurrahman Başcı, Alper Ağca, Engin Bilge Özgürhan, Cengiz Alagöz, Ali Demircan, Ahmet Demirok
OBJECTIVES: To compare the postoperative biomechanical properties of the cornea after photorefractive keratectomy (PRK) and small incision lenticule extraction (SMILE) in eyes with low and moderate myopia. MATERIALS AND METHODS: We retrospectively examined 42 eyes of 23 patients undergoing PRK and 42 eyes of 22 patients undergoing SMILE for the correction of low and moderate myopia. Corneal hysteresis (CH) and corneal resistance factor (CRF) were measured with an Ocular Response Analyzer before and 6 months after surgery...
April 2016: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/27789481/long-term-course-of-patients-with-primary-ocular-adnexal-malt-lymphoma-a-large-single-institution-cohort-study
#13
Amrita Desai, Madhura G Joag, Lazaros Lekakis, Jennifer R Chapman, Francisco Vega, Robert Tibshirani, David Tse, Arnold Markoe, Izidore S Lossos
While Primary Ocular Adnexal MALT Lymphoma (POAML) is the most common orbital tumor, there are large gaps in knowledge of its natural history. We conducted a retrospective analysis of the largest reported cohort, consisting of 182 patients with POAML, diagnosed or treated at our institution to analyze long-term outcome, response to treatment, incidence and localization of relapse and transformation. The majority of patients (80%) presented with stage I disease. Overall, 84% of treated patients achieved a complete response after first-line therapy...
October 27, 2016: Blood
https://www.readbyqxmd.com/read/27785411/gene-mapping-in-an-anophthalmic-pedigree-of-a-consanguineous-pakistani-family-opened-new-horizons-for-research
#14
S Saleha, M Ajmal, S Zafar, A Hameed
Clinical anophthalmia is a rare inherited disease of the eye and phenotype refers to the absence of ocular tissue in the orbit of eye. Patients may have unilateral or bilateral anophthalmia, and generally have short palpebral fissures and small orbits. Anophthalmia may be isolated or associated with a broader syndrome and may have genetic or environmental causes. However, genetic cause has been defined in only a small proportion of cases, therefore, a consanguineous Pakistani family of the Pashtoon ethnic group, with isolated clinical anophthalmia was investigated using linkage mapping...
July 1, 2016: Balkan Journal of Medical Genetics: BJMG
https://www.readbyqxmd.com/read/27770479/hidden-mechanisms-beyond-the-pupillary-block-in-acute-angle-closure-ultrasound-biomicroscopic-study
#15
Yanin Suwan, Sunpong Jiamsawad, Wasu Supakontanasan, Chaiwat Teekhasaenee
BACKGROUND: To evaluate the mechanisms of acute angle-closure (AAC) other than the pupillary block using ultrasound biomicroscopy DESIGN: Retrospective chart review. PARTICIPANTS: All patients who were diagnosed with AAC in Ramathibodi Hospital, Bangkok, Thailand, between June 2011 and February 2015 were enrolled. METHODS: 72 patients who were diagnosed with AAC underwent a detailed ocular examination. The diagnosed mechanism of AAC was confirmed by UBM and ocular biometry...
October 22, 2016: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/27768119/effect-of-glucosamine-on-intraocular-pressure-a-randomized-clinical-trial
#16
H Esfandiari, M Pakravan, Z Zakeri, S Ziaie, P Pakravan, V Ownagh
PurposeThe purpose of the study was to investigate ocular hypertensive effect of exogenous glucosamine in comparison with placebo in patients with osteoarthritis.Patients and methodsIn this double-masked randomized clinical trial, 88 patients with osteoarthritis were included. Forty-four patients were randomized into either glucosamine sulfate or the placebo group.Comprehensive ophthalmologic exam including intraocular pressure (IOP) at baseline, month 1, and 3 was performed. Ocular response analyzer parameters were also checked at baseline and month 3...
October 21, 2016: Eye
https://www.readbyqxmd.com/read/27755162/subtenon-injections-of-ranibizumab-arrest-growth-in-early-recurrent-pterygium
#17
Linda Rose, Julia M Byrd, Yousuf Qaseem
IMPORTANCE: Currently the only treatment for recurrent pterygium is surgery. This is a phase 1 trial investigating ranibizumab as a medical treatment for recurrent pterygium. OBJECTIVE: To assess the safety and efficacy of subtenon Ranibizimab for recurrent pterygia. DESIGN: Subjects with recurrent pterygium received subtenon ranibizumab and were followed for 1 year. Safety parameters were measured. Photographs were taken and quantitatively analyzed to measure the short-term (2 months) and long-term (5-26 months) response to treatment...
October 7, 2016: Eye & Contact Lens
https://www.readbyqxmd.com/read/27750284/altered-refractive-development-in-mice-with-reduced-levels-of-retinal-dopamine
#18
Michael A Bergen, Han Na Park, Ranjay Chakraborty, Erica G Landis, Curran Sidhu, Li He, P Michael Iuvone, Machelle T Pardue
Purpose: The neuromodulator dopamine (DA) has been implicated in the prevention of excessive ocular elongation and myopia in various animal models. This study used retina-specific DA knockout mice to investigate the role of retinal DA in refractive development and susceptibility to experimental myopia. Methods: Measurements of refractive error, corneal curvature, and ocular biometrics were obtained as a function of age for both untreated and form-deprived (FD) groups of retina-specific tyrosine hydroxylase knockout (rTHKO) and control (Ctrl) mice...
August 1, 2016: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/27709370/biomechanical-evaluation-of-cornea-in-patients-with-ankylosing-spondylitis
#19
Mehtap Caglayan, Ozge Sarac, Pinar Kosekahya, Sukran Erten, Berna Ayan, Nurullah Cagil
PURPOSE: The aim of this study was to evaluate the corneal biomechanical parameters in patients with ankylosing spondylitis (AS) and to compare them with the healthy subjects. METHODS: Sixty patients with AS (study group) and 60 healthy subjects (control group) were enrolled in this prospective study. The study group was further classified as active (n:30) and inactive (n:30). After detailed ophthalmological examination including intraocular pressure (IOP) measurement with Goldmann applanation tonometer (IOPGAT), corneal hysteresis (CH), corneal resistance factor (CRF), corneal-compensated IOP (IOPcc), and Goldmann-correlated IOP (IOPg) were measured with the Reichert Ocular Response Analyzer (ORA)...
October 5, 2016: International Ophthalmology
https://www.readbyqxmd.com/read/27703662/in-vivo-evaluation-of-the-biomechanical-properties-of-optic-nerve-and-peripapillary-structures-by-ultrasonic-shear-wave-elastography-in-glaucoma
#20
Atilla Suleyman Dikici, Ismail Mihmanli, Fahrettin Kilic, Ahmet Ozkok, Gokhan Kuyumcu, Pinar Sultan, Cesur Samanci, Mehmet Halit Yilmaz, Babak Rafiee, Nevbahar Tamcelik, Zehra Isik Hasiloglu, Fatih Kantarci
BACKGROUND: Primary open-angle glaucoma is a multifactorial serious disease characterized by progressive retinal ganglion cell death and loss of visual field. OBJECTIVES: The purposes of this study were to investigate shear wave elastography (SWE) use in the evaluation of the optic nerve (ON) and peripapillary structures, and to compare the findings between glaucomatous and control eyes. PATIENTS AND METHODS: A case-controlled study, including 21 patients with primary open-angle glaucoma and 21 age-matched control subjects, was carried out...
April 2016: Iranian Journal of Radiology: a Quarterly Journal Published By the Iranian Radiological Society
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