keyword
MENU ▼
Read by QxMD icon Read
search

ocular response analyzer

keyword
https://www.readbyqxmd.com/read/29221851/ccr5-chemokine-receptor-gene-polymorphisms-in-ocular-toxoplasmosis
#1
Geraldo M de Faria, Christiane M Ayo, Amanda P de Oliveira, Alessandro G Lopes, Fábio B Frederico, Aparecida P Silveira-Carvalho, Mariana Previato, Amanda P Barbosa, Fernando H A Murata, Gildásio Castello de Almeida, Rubens Camargo Siqueira, Luiz C de Mattos, Cinara C Brandão de Mattos
C-C chemokine receptor type 5 (CCR5) is a chemokine receptor that influences the immune response to infectious and parasitic diseases. This study aimed to determine whether the CCR5Δ32 and CCR5 59029 A/G polymorphisms are associated with the development of ocular toxoplasmosis in humans. Patients with positive serology for Toxoplasma gondii were analyzed and grouped as 'with ocular toxoplasmosis' (G1: n=160) or 'without ocular toxoplasmosis' (G2: n=160). A control group (G3) consisted of 160 individuals with negative serology...
December 5, 2017: Acta Tropica
https://www.readbyqxmd.com/read/29212484/clinical-features-of-visual-disturbances-secondary-to-isolated-sphenoid-sinus-inflammatory-diseases
#2
Lanlan Chen, Libin Jiang, Bentao Yang, Prem S Subramanian
BACKGROUND: Visual disturbances associated with isolated sphenoid sinus inflammatory diseases (ISSIDs) are easily misdiagnosed due to the nonspecific symptoms and undetectable anatomical location. The main objective of this retrospective case series is to investigate the clinical features of visual disturbances secondary to ISSIDs. METHODS: Clinical data of 23 patients with unilateral or bilateral visual disturbances secondary to ISSIDs from 2004 to 2014 with new symptoms were collected...
December 6, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/29200820/the-effect-of-flap-thickness-on-corneal-biomechanics-after-myopic-laser-in-situ-keratomileusis-using-the-m-2-microkeratome
#3
Iyad A Goussous, Mohamed-Sameh El-Agha, Ahmed Awadein, Mohamed H Hosny, Alaa A Ghaith, Ahmed L Khattab
Purpose: The purpose of this study was to determine the effect of flap thickness on corneal biomechanics after myopic laser in situ keratomileusis (LASIK). Methods: This is a prospective controlled non-randomized, institutional study. Patients underwent either epi-LASIK with mitomycin (advanced surface ablation [ASA]), thin-flap LASIK (90 µm head), or thick-flap LASIK (130 µm head). In ASA, the Moria Epi-K hydroseparator was used. LASIK flaps were created using the Moria M-2 mechanical microkeratome...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29168044/potential-selection-bias-in-candidates-for-stereotactic-radiotherapy-for-neovascular-amd
#4
Christoph Ehlken, Daniel Böhringer, Hansjürgen T Agostini, Bastian Grundel, Milena Stech
PURPOSE: Stereotactic radiotherapy (SRT, IRay) was able to reduce the need for intravitreal injections of anti-VEGF (IVI) in patients with neovascular AMD (nAMD) in a phase II randomized clinical trial. Certain morphologic characteristics, such as lesion size < 4 mm(2) or lack of fibrosis, were associated with a better response. The purpose of this cross-sectional study was to investigate eligibility for SRT in a clinical routine setting and to compare clinical features of eligible and non-eligible patients...
November 22, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29165402/quercetin-mitigates-inflammatory-responses-induced-by-vascular-endothelial-growth-factor-in-mouse-retinal-photoreceptor-cells-through-suppression-of-nuclear-factor-kappa-b
#5
Minsup Lee, Seohyeon Yun, Hyesook Lee, Jaewook Yang
Retinal vascular endothelial growth factor (VEGF) increased by neovascularization is well known as a pathogenic factor in ocular neovascular diseases. However, it is still unclear how retinal neurons are damaged by VEGF. The aims of this study are to demonstrate the inflammatory protein expression regulated by VEGF using mouse photoreceptor-derived cells and the protective effect of quercetin against VEGF-induced inflammatory response. Expression and phosphorylation of protein and expression of mRNA were detected by immunoblot and reverse transcriptase polymerase chain reaction...
November 22, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29162437/mouse-model-of-alagille-syndrome-and-mechanisms-of-jagged1-missense-mutations
#6
Emma R Andersson, Indira V Chivukula, Simona Hankeova, Marika Sjöqvist, Yat Long Tsoi, Daniel Ramsköld, Jan Masek, Aiman Elmansuri, Anita Hoogendoorn, Elenae Vazquez, Helena Storvall, Julie Netušilová, Meritxell Huch, Björn Fischler, Ewa Ellis, Adriana Contreras, Antal Nemeth, Kenneth C Chien, Hans Clevers, Rickard Sandberg, Vitezslav Bryja, Urban Lendahl
BACKGROUND & AIMS: Alagille syndrome is a genetic disorder characterized by cholestasis, ocular abnormalities, characteristic facial features, heart defects, and vertebral malformations. Most cases are associated with mutations in JAGGED1 (JAG1), which encodes a Notch ligand, although it is not clear how these contribute to disease development. We aimed to develop a mouse model of Alagille syndrome to elucidate these mechanisms. METHODS: Mice with a missense mutation (H268Q) in Jag1 (Jag1(+)/(Ndr) mice) were outbred to a C3H/C57bl6 background to generate a mouse model for Alagille syndrome (Jag1(Ndr/Ndr) mice)...
November 18, 2017: Gastroenterology
https://www.readbyqxmd.com/read/29160542/corneal-biomechanical-features-in-patients-with-ankylosing-spondylitis
#7
Kubra Serefoglu Cabuk, Emine Isil Üstün, Kursat Atalay, Ahmet Kirgiz, Rukiye Aydin
PURPOSE: To evaluate the corneal biomechanical features and central corneal thickness in ankylosing spondylitis patients and to evaluate correlations of these parameters with disease activity. METHODS: The study included 51 patients diagnosed with ankylosing spondylitis (mean age, 40.80 ± 13.15 years; range, 18-72 years) and 34 age- and sex-matched healthy controls (mean age, 42.00 ± 12.32 years; range, 18-60 years). All underwent a complete ophthalmological and physical examination, including visual acuity testing and biomicroscopic anterior and posterior segment examinations...
September 2017: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/29144051/infantile-hemangiomas-with-conjunctival-involvement-an%C3%A2-underreported-occurrence
#8
Martin Theiler, Eulalia Baselga, Christina Gerth-Kahlert, Erin F Mathes, Agnes Schwieger-Briel, Karla Chaloupka, Lisa Weibel, Ilona J Frieden
BACKGROUND/OBJECTIVES: Infantile hemangiomas (IHs) involving the conjunctiva are only anecdotally reported in the literature and little is known about their clinical course. In a retrospective case series we aimed to better delineate the clinical presentation, complications, and response to treatment of this uncommon subtype of IH. A classification of conjunctival IH is proposed. METHODS: Medical charts at three academic pediatric dermatology institutions were retrospectively analyzed...
November 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/29123243/immunohistochemical-detection-of-propionibacterium-acnes-in-the-retinal-granulomas-in-patients-with-ocular-sarcoidosis
#9
Kenji Nagata, Yoshinobu Eishi, Keisuke Uchida, Kazuhito Yoneda, Hiroki Hatanaka, Toru Yasuhara, Maho Nagata, Chie Sotozono, Shigeru Kinoshita
The etiology of sarcoidosis is still obscure; however, Mycobacteria and Propionibacterium acnes are considered the most implicated etiological agent for sarcoidosis. To investigate whether P. acnes is an etiological agent for sarcoid uveitis, we analyzed the frequency of P. acnes detected within the biopsied retinas from patients with ocular sarcoidosis by immunohistochemistry with a P. acnes-specific monoclonal antibody (PAB antibody). Eleven patients (12 eyes) with sarcoid uveitis were enrolled in this study...
November 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29110566/predicting-the-outcome-after-acute-unilateral-vestibulopathy-analysis-of-vestibulo-ocular-reflex-gain-and-catch-up-saccades
#10
Niccolò Cerchiai, Elena Navari, Stefano Sellari-Franceschini, Chiara Re, Augusto Pietro Casani
Objectives (1) To describe the relationships among the main instrumental features characterizing an acute unilateral vestibulopathy and (2) to clarify the role of the video head impulse test in predicting the development of chronic vestibular insufficiency. Study Design Case series with chart review. Setting Tertiary referral center. Subjects and Methods Sixty patients suffering from acute unilateral vestibulopathy were retrospectively analyzed: 30 who recovered spontaneously (group 1) and 30 who needed a vestibular rehabilitation program (group 2)...
November 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29109715/specific-detection-of-serum-antibodies-against-bkpyv-a-small-dna-tumour-virus-in-patients-affected-by-choroidal-nevi
#11
Silvia Pietrobon, Ilaria Bononi, Francesca Lotito, Paolo Perri, Sara Violanti, Elisa Mazzoni, Fernanda Martini, Mauro G Tognon
Ocular or choroidal nevus (CN) is a rare benign neoplastic lesion of the eye. The cause of CN onset/progression, which arises from the transformation of ocular melanocytes, is not known. A fraction of CN patients may develop uveal melanoma. The objective of this study was to investigate the association between CN and BK polyomavirus (BKPyV), a small DNA tumor virus. Serum IgG antibodies which react with BKPyV antigens were analyzed. An indirect E.L.I.S.A. using synthetic peptides that mimic BKPyV antigens was employed...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29104870/age-related-variations-of-rabbit-corneal-geometrical-and-clinical-biomechanical-parameters
#12
Haixia Zhang, Xiao Qin, Xiaomeng Cao, Di Zhang, Lin Li
Purpose: To study the variations in corneal clinical biomechanical parameters (CCBP) and corneal geometrical parameters of rabbit in relation to age. Methods: Rabbits aged 3, 7, 12, 18, and 24 months were enrolled. Each eye of the rabbits was tested with Ocular Response Analyzer (ORA), Optical Coherence Tomography (OCT), and Pachymeter to obtain the intraocular pressure (IOP): Goldmann-correlated IOP (IOPg) and Corneal Compensated Intraocular Pressure (IOPcc); CCBP: Corneal Hysteresis (CH) and Corneal Resistance Factor (CRF); corneal geometric parameters: corneal curvature radius (CCR) and central corneal thickness (CCT)...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29093698/the-role-of-predictability-in-saccadic-eye-responses-in-the-suppression-head-impulse-test-of-horizontal-semicircular-canal-function
#13
Jorge Rey-Martinez, Joaquin Yanes, Jonathan Esteban, Ricardo Sanz, Eduardo Martin-Sanz
Background: In the suppression head impulse paradigm (SHIMP) vHIT protocol, the participant is instructed to follow with his gaze a mobile target generated by a laser placed on the participant's head. Recent studies have reported that the refixation saccade latencies are in relation with the time evolution of the vestibular dysfunction in both (standard and SHIMP) procedures. We hypothesized that some central mechanisms like head impulse prediction could be one of the causes for the differences in the saccadic eye responses...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/29082447/impact-of-herpetic-stromal-immune-keratitis-in-corneal-biomechanics-and-innervation
#14
Manuel Ángel Marcos-Fernández, Sara Sánchez Tabernero, Jose María Herreras, David José Galarreta
PURPOSE: To study corneal innervation in eyes with history of herpetic keratitis and its correlation with corneal sensitivity and biomechanical properties. METHODS: A total of 56 eyes were included, of which 16 had a history of unilateral immune stromal herpetic keratitis, 16 were their contralateral eyes, and 20 were healthy controls. Structural analysis of corneal nerve plexus was performed by confocal microscopy. Biomechanical properties were measured with the Ocular Response Analyzer...
October 29, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29077584/comfort-ocular-dryness-and-equilibrium-water-content-changes-of-daily-disposable-contact-lenses
#15
Eduardo Insua Pereira, Madalena Lira
OBJECTIVES: The objective of this investigation was to evaluate the level of comfort and ocular dryness during wear with six daily disposable contact lenses (DDCL) and also determine the changes in contact lens equilibrium water content (EWC) resulting from their wear. METHODS: In this contralateral open trial, 27 subjects were randomly fitted with six DDCL (stenfilcon A, delefilcon A, nelfilcon A, narafilcon A, nesofilcon A, and omafilcon A). The evaluation of comfort and ocular dryness sensation was recorded by the participants at two moments of the day (11 AM and 5 PM) over a period of 10 days of contact lens wear...
October 26, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/29074386/unlike-th1-th17%C3%A2-cells-th2-th9-cells-selectively-migrate-to-the-limbus-conjunctiva-and-initiate-an-eosinophilic-infiltration-process
#16
Cuiyan Tan, Wambui S Wandu, Anthony St Leger, Jennifer Kielczewski, Eric F Wawrousek, Chi-Chao Chan, Igal Gery
In this study we compared polarized mouse T-helper (Th) lymphocytes of four populations, sensitized against an ocular antigen, for their patterns of migration and induction of inflammatory processes in recipient mouse eyes expressing the target antigen. Th1, Th2, Th9 and Th17 cells transgenically expressing T-cell receptor (TCR) specific against hen egg lysozyme (HEL) were adoptively transferred to recipient mice expressing HEL in their eyes. Recipient eyes collected 4 or 7 days post injection were analyzed for histopathological changes...
October 24, 2017: Experimental Eye Research
https://www.readbyqxmd.com/read/29060092/analysis-of-computerized-optokinetic-nystagmus-induction-and-effect-of-contrast-on-ocular-fatigue
#17
Ji Sung Kim, Changhoon Baek, Sunyoung Yoo, Jeong-Min Hwang, Jong Mo Seo
Optokinetic nystagmus (OKN) is useful in evaluating visual function objectively, and the classical black-and-white-striped OKN drum is being replaced by video or computer monitor. However, the examinee may feel fatigue during test because of high contrast of luminous pattern from monitor. This paper suggests a plan to reduce eye fatigue of participant by decreasing contrast of patterns without reducing OKN response. Alternating black and white stripes are shown on flat-panel liquid-crystal display monitor and moved horizontally to evoke OKN of the examinee, and the OKN wasW observed through electrooculography (EOG)...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29050157/-observation-of-clinical-and-electrophysiological-features-in-patients-with-distal-myasthenia-gravis
#18
F Jian, H B Wang, N Chen, S Yang, Y Liu, Y Z Zhao, L Zhang, H Pan, X H Zhang
Objective: To explore the clinical and electrophysiological features and prognosis of distal myasthenia gravis (MG). Methods: Data of MG patients in Beijing Tiantan Hospital from October 2016 to March 2017 were reviewed, including thorough neurological examinations, nerve conduction studies, repetitive nerve stimulations (RNS) and needle electromyographies. Distal MG patients were included and were analyzed as to their clinical and electrophysiological features and response to treatments. Results: Four patients (7...
October 10, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29042748/corneal-biomechanical-properties-after-laser-assisted-in-situ-keratomileusis-and-photorefractive-keratectomy
#19
Eileen S Hwang, Brian C Stagg, Russell Swan, Carlton R Fenzl, Molly McFadden, Valliammai Muthappan, Luis Santiago-Caban, Mark D Mifflin, Majid Moshirfar
BACKGROUND: The purpose of this study was to evaluate the effects of laser-assisted in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK) on corneal biomechanical properties. METHODS: We used the ocular response analyzer to measure corneal hysteresis (CH) and corneal resistance factor (CRF) before and after refractive surgery. RESULTS: In all, 230 eyes underwent LASIK and 115 eyes underwent PRK without mitomycin C (MMC). Both procedures decreased CH and CRF from baseline...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29032108/pregnancy-induced-changes-in-corneal-biomechanics-and-topography-are-thyroid-hormone-related
#20
David Tabibian, Begoña M de Tejada, Zisis Gatzioufas, Sabine Kling, Vanessa S Meiss, Marc-Olivier Boldi, Véronique Othenin-Girard, Antonina Chilin, Julien Lambiel, Florence Hoogewoud, Farhad Hafezi
PURPOSE: To identify biomechanical and topographic changes of the cornea during pregnancy and the postpartum period and its association to hormonal changes. DESIGN: Prospective single-center observational cohort study. METHODS: Participants were 24 pregnant women (48 eyes), monitored throughout pregnancy and after delivery. Biomechanical and topographic corneal properties were measured using the Ocular Response Analyzer (ORA) and a Scheimpflug imaging system (Pentacam HR) each trimester and 1 month after delivery...
October 13, 2017: American Journal of Ophthalmology
keyword
keyword
68887
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"