keyword
https://read.qxmd.com/read/36730373/recurrent-keratoconus-corneal-transplants-for-keratoconus-develop-tomographic-ectatic-changes
#21
JOURNAL ARTICLE
Maria Miura, Pia Leon, Yoav Nahum, Myriam S Böhm, Michael Mimouni, Michael W Belin, Lynette Johns, Joseph B Ciolino
PURPOSE: The purpose of this study was to evaluate postoperative Scheimpflug imaging changes during the first 5 years after penetrating keratoplasty (PK) in patients with keratoconus (KC). METHODS: This retrospective, interventional case series includes 31 eyes of 31 patients who underwent their first PK with a history of KC. Postoperative Scheimpflug imaging was performed 3 months after the removal of the last suture (baseline) and then repeated 3 and 5 years after the PK...
November 21, 2022: Cornea
https://read.qxmd.com/read/36728315/corneal-fourier-and-belin-ambr%C3%A3-sio-enhanced-ectasia-analysis-in-healthy-4-year-old-white-children
#22
JOURNAL ARTICLE
Dunja Bajtl, Mirjana Bjeloš, Mladen Bušić, Ana Ćurić, Dubravka Biuk, Josip Barać
PURPOSE: The aim of this study was to provide normative databases of Fourier analysis (FA) and Belin-Ambrósio enhanced ectasia display (BAD) in healthy White 4-year-old emmetropic children. METHODS: FA parameters analyzed were spherical component (SRmin), spherical eccentricity (SEcc), maximal decentration (MD), regular astigmatism at the center (Astigm. C) and periphery (Astigm. P), and irregularity (I). The parameters obtained by BAD included summary indicator BAD D, anterior corneal curvature (K1 and K2, D), maximal keratometry (Kmax, D), maximal Ambrósio relational thinnest (ART max), and pachymetric and BAD indices...
January 12, 2023: Cornea
https://read.qxmd.com/read/36305911/reliability-analysis-of-successive-corvis-st%C3%A2-measurements-in-keratoconus-2-years-after-accelerated-corneal-crosslinking-compared-to-untreated-keratoconus-corneas
#23
JOURNAL ARTICLE
Kassandra Xanthopoulou, Berthold Seitz, Michael W Belin, Elias Flockerzi
PURPOSE: To assess the reliability of successive Corvis ST® measurements (CST, Oculus, Wetzlar, Germany) in keratoconus (KC) ≥ 2 years after accelerated corneal crosslinking (9 mW/cm2 , 10 min, 5.4 J/cm2 ) compared to untreated KC corneas. METHODS: Three successive CST measurements per eye were performed in ≥ 2 years after CXL (CXLG, n = 20 corneas of 16 patients) and a control group consisting of non-operated, ABC-stage-matched KC corneas according to Belin's ABCD KC grading (controls, n = 20 corneas, 20 patients)...
October 28, 2022: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/36255612/analysis-of-the-diagnostic-accuracy-of-belin-ambr%C3%A3-sio-enhanced-ectasia-and-corvis-st-parameters-for-subclinical-keratoconus
#24
JOURNAL ARTICLE
Yaowen Song, Yi Feng, Min Qu, Qiuxia Ma, Huiqin Tian, Dan Li, Rui He
OBJECTIVE: To investigate the diagnostic accuracy of the parameters in the Belin/Ambrósio Enhanced Ectasia Display built in Pentacam, which is designed for the screening of subclinical keratoconus (SKC) built in Pentacam, and the parameters in Corneal visualization Scheimpflug technology (Corvis ST). METHODS: A retrospective study: The fellow eyes of unilateral keratoconus cases were diagnosed with SKC. Patients presented to Shanxi Eye Hospital with SKC from October 2020 to November 2021 were included as the SKC group, and myopic patients undergoing corneal refractive surgery at the Refractive Surgery Department in our hospital within the same period were included as the control group...
October 18, 2022: International Ophthalmology
https://read.qxmd.com/read/36186827/corneal-characteristics-in-down-syndrome-patients-with-normal-and-keratoconic-cornea
#25
JOURNAL ARTICLE
Hassan Hashemi, Soheila Asgari
Purpose: To determine the reference range of corneal indices in Down syndrome patients with normal corneas (DS-N) and to compare it with the corneal indices in Down syndrome patients with keratoconic corneas (DS-KC). Methods: A study was conducted using the data of 154 eyes of 154 DS-N and 25 eyes of 25 DS-KC patients. Eighteen indices related to thickness, anterior chamber, keratometry, elevation, and aberrations routinely used for KC diagnosis were extracted from the Pentacam...
2022: Frontiers in Medicine
https://read.qxmd.com/read/36173242/epismart%C3%A2-crosslinking-for-keratoconus-a-phase-2-study
#26
JOURNAL ARTICLE
Randy J Epstein, Michael W Belin, Deborah Gravemann, Roxanne Littner, Roy S Rubinfeld
PURPOSE: The aim of this study was to assess changes in visual acuity after epithelium-on ("epi-on") corneal crosslinking after a diagnosis of keratoconus. METHODS: Subjects with corneal ectatic diseases were enrolled in a prospective, randomized, controlled, open-label, multicenter trial. Subjects were randomized to 1 of 3 treatment groups and treated with an epi-on crosslinking system including riboflavin/sodium iodide and pulsed UVA exposure (EpiSmart® , CXL Ophthalmics, Encinitas, CA)...
September 29, 2022: Cornea
https://read.qxmd.com/read/36147272/comparing-pentacam-hr-screening-indices-in-different-normal-corneal-thicknesses-among-refractive-surgery-candidates
#27
JOURNAL ARTICLE
Leila Ghiasian, Parya Abdolalizadeh, Ali Hadavandkhani, Acieh Eshaghi, Yasaman Hadi, Fatemeh Nadjafi-Semnani
PURPOSE: To compare Pentacam indices in normal eyes with different corneal thicknesses. METHODS: It is a retrospective observational study. Ninety-six normal eyes of 96 patients who were referred for refractive surgery in a tertiary university-based hospital from October 2015 to April 2019 were recruited consecutively. Corneal keratometry as well as Pentacam's software Belin-Ambrósio Enhanced Ectasia Display (BAD) parameters including pachymetry progression indices (PPIs), maximum Ambrosio's relational thickness (ART-max), corneal elevations, normalized deviations, BAD total deviation value (BAD-D), and anterior surface indices were measured by Pentacam HR (Type 70900)...
2022: Journal of Current Ophthalmology
https://read.qxmd.com/read/36137997/influence-of-specialty-contact-lens-wear-on-posterior-corneal-tomography-in-keratoconus-subjects
#28
JOURNAL ARTICLE
Isabel Deboutte, Elke O Kreps, Jos J Rozema, Maarten van Hoey, Lieselotte Anthonissen, Carina Koppen
OBJECTIVE: To evaluate the effect of specialty contact lens (CL) wear on posterior corneal tomography in keratoconus subjects. METHODS: Patients with keratoconus who were wearing specialty CL were included in this retrospective cohort study. Tomographic parameters were evaluated with Scheimpflug imaging (Pentacam HR) before lens fitting and immediately after removal of CLs worn habitually for a period of several months. Subjects were divided into groups, according to type of lens (corneal, scleral, and hybrid) and keratoconus severity based on Belin/Ambrosio D (BAD-D) score, for further analysis...
September 21, 2022: Eye & Contact Lens
https://read.qxmd.com/read/35990537/acute-hydrops-with-total-corneal-edema-in-a-very-young-child-with-keratoconus-the-youngest-age-reported-case
#29
Mohammad-Reza Sedaghat, Hamed Momeni-Moghaddam, Michael W Belin, Maryam Savardashtaki, Shehzad A Naroo, Hassan Robabi
Purpose: To present the youngest age ever reported for acute corneal hydrops with total corneal edema in a child with advanced bilateral keratoconus. Methods: Patient presentation in ophthalmic clinic. The patient underwent various clinical tests and examinations including anterior segment optical coherence tomography (AS-OCT) and Scheimpflug corneal tomography. Results: A 5-year-old girl presented with uncorrected distance visual acuity (UDVA) of 0...
2022: Case Reports in Ophthalmological Medicine
https://read.qxmd.com/read/35860103/keratoconus-detected-by-corneal-topography-in-patients-seeking-refractive-surgery-in-jazan-region-saudi-arabia-a-retrospective-cross-sectional-study
#30
JOURNAL ARTICLE
Ismail Abuallut, Ahmed Ageeli, Mohammed Shami, Mohammed Bosaily, Aisha Majrashi, Shahad Shabaan, Majd Moafa, Wassem Zakri, Asma Abdulazim, Walid Barakat
Background: Keratoconus is a non-inflammatory, chronic, idiopathic, corneal disease characterized by thinning of the core or paracentral part of the cornea. In this study, we demonstrate the prevalence of keratoconus among patients seeking refractive surgery using laser vision correction (LVC) at the Department of Ophthalmology, Private Eye Center, Jazan, Saudi Arabia. Materials and methods: A retrospective cross-sectional study was undertaken with the data from January 1, 2019 to December 31, 2019 in the ophthalmology department of Jazan city...
July 2022: Annals of Medicine and Surgery
https://read.qxmd.com/read/35714335/systematic-detection-of-keratoconus-in-oct-corneal-and-epithelial-thickness-maps
#31
JOURNAL ARTICLE
Burcu Yücekul, H Burkhard Dick, Suphi Taneri
PURPOSE: To detect keratoconus (KC) only by analyzing the corneal and epithelial map parameters and patterns in optical coherence tomography (OCT). SETTING: Tertiary care refractive surgery center. DESIGN: Retrospective data collection. METHODS: Corneal and epithelial thickness maps of normal, manifest, and subclinical keratoconic eyes (according to the Belin-Ambrosio display, Pentacam) were evaluated using spectral-domain OCT (Zeiss Cirrus 5000 HD)...
December 1, 2022: Journal of Cataract and Refractive Surgery
https://read.qxmd.com/read/35702687/pachymetric-assessment-after-epismart-%C3%A2-epithelium-on-cross-linking-for-keratoconus-and-post-surgical-ectasia
#32
JOURNAL ARTICLE
Neel S Vaidya, Arvin Daneshmand, Randy J Epstein, Parag A Majmudar, Michael W Belin, Edward C Parsons, Roy S Rubinfeld
Purpose: To assess the change in corneal pachymetry after a novel epithelium-on (EpiSmart® ) corneal crosslinking procedure (CXL). Methods: Eyes treated as part of the open-label, non-controlled arm of the study "Collagen Crosslinking with Ultraviolet-A in Asymmetric Corneas" (NCT01097447) were examined at baseline, 3-, 6- and 12-months post-CXL. Thinnest pachymetry readings based on Pentacam (OCULUS GmbH, Wetzlar, Germany) were recorded. Results: A total of 101 eyes met the study inclusion criteria...
2022: Clinical Ophthalmology
https://read.qxmd.com/read/35686712/evaluation-of-corneal-biomechanical-indices-in-distinguishing-between-normal-very-asymmetric-and-bilateral-keratoconic-eyes
#33
JOURNAL ARTICLE
Robert Herber, Azar Hasanli, Janine Lenk, Riccardo Vinciguerra, Naim Terai, Lutz E Pillunat, Frederik Raiskup
PURPOSE: To evaluate the ability of biomechanical indices provided by the Ocular Response Analyzer (ORA; Reichert Ophthalmic Instruments) and dynamic Scheimpflug analyzer (Corvis ST; Oculus Optikgeräte GmbH) to distinguish between normal eyes and eyes with very asymmetric ectasia (VAE) and mild and moderate keratoconus. METHODS: This prospective, observational, and monocentric study included normal eyes (defined as keratoconus percentage index < 60, Belin/Ambrósio total deviation value [BAD-D] < 1...
June 2022: Journal of Refractive Surgery
https://read.qxmd.com/read/35686708/combining-spectral-domain-oct-and-air-puff-tonometry-analysis-to-diagnose-keratoconus
#34
JOURNAL ARTICLE
Nan-Ji Lu, Ahmed Elsheikh, Jos J Rozema, Nikki Hafezi, Ioannis M Aslanides, Mark Hillen, Daniel Eckert, Christian Funck, Carina Koppen, Le-Le Cui, Farhad Hafezi
PURPOSE: To investigate the diagnostic capacity of spectral-domain optical coherence tomography (SD-OCT) combined with air-puff tonometry using artificial intelligence (AI) in differentiating between normal and keratoconic eyes. METHODS: Patients who had either undergone uneventful laser vision correction with at least 3 years of stable follow-up or those who had forme fruste keratoconus (FFKC), early keratoconus (EKC), or advanced keratoconus (AKC) were included...
June 2022: Journal of Refractive Surgery
https://read.qxmd.com/read/35333829/new-artificial-intelligence-index-based-on-scheimpflug-corneal-tomography-to-distinguish-subclinical-keratoconus-from-healthy-corneas
#35
MULTICENTER STUDY
Gildásio Castello Almeida, Rodrigo Capobianco Guido, Henrique Monteiro Balarin Silva, Cinara Cássia Brandão, Luiz Carlos de Mattos, Bernardo T Lopes, Aydano Pamponet Machado, Renato Ambrósio
PURPOSE: To assess the efficiency of an index derived from multiple logistic regression analysis (MLRA) to measure differences in corneal tomography findings between subclinical keratoconus (KC) in 1 eye, corneal ectasia, and healthy corneas. SETTING: 2 private Brazilian ophthalmological centers. DESIGN: Multicenter case-control study. METHODS: This study included 187 eyes with very asymmetric ectasia and with normal corneal topography and tomography (VAE-NTT) in the VAE-NTT group, 2296 eyes with healthy corneas in the control group (CG), and 410 eyes with ectasia in the ectasia group...
October 1, 2022: Journal of Cataract and Refractive Surgery
https://read.qxmd.com/read/35082233/mapping-of-corneal-birefringence-in-thin-and-asymmetric-keratoconus-corneas-with-ultrahigh-resolution-polarization-sensitive-oct
#36
JOURNAL ARTICLE
Rahul Patil, Rohit Shetty, Raghav Narasimhan, Yash Patel, Pooja Khamar, Michael Pircher, Christoph K Hitzenberger, Rudy M M A Nuijts, Abhijit Sinha Roy
PURPOSE: To evaluate phase retardation (PR) across healthy eyes and eyes with thin corneas (<500 μm) and with asymmetric and bilateral keratoconus (KC). SETTING: Narayana Nethralaya Eye Hospital, Bangalore, India. DESIGN: Observational cross-sectional. METHODS: There were 4 eye groups: healthy eyes (Group 1; n = 10 eyes), eyes with thin corneas and no clinical disease (Group 2; n = 10 eyes), eyes with asymmetric KC (Group 3; n = 5 eyes), and eyes with clinical KC (Group 4; n = 15 eyes)...
August 1, 2022: Journal of Cataract and Refractive Surgery
https://read.qxmd.com/read/35060771/comparison-of-artificial-intelligence-based-machine-learning-classifiers-for-early-detection-of-keratoconus
#37
JOURNAL ARTICLE
Mehrdad Mohammadpour, Zahra Heidari, Hassan Hashemi, Mehdi Yaseri, Akbar Fotouhi
PURPOSE: To compare the agreement between artificial intelligence (AI)-based classifiers and clinical experts in categorizing normal cornea from ectatic conditions. METHODS: Prospective diagnostic test study at Noor Eye Hospital. Two hundred twelve eyes of 212 patients were categorized into three groups of 92 normal, 52 subclinical keratoconus (SKCN), and 68 KCN eyes based on clinical findings by 3 independent expert examiners. All cases were then categorized using four different classifiers: Pentacam Belin/Ambrosio enhanced ectasia total deviation value (BADD) and Topographic Keratoconus Classification (TKC), Sirius Phoenix, and OPD-Scan III Corneal Navigator...
May 2022: European Journal of Ophthalmology
https://read.qxmd.com/read/34855828/the-utility-of-measures-of-anterior-segment-parameters-of-a-pentacam-scheimpflug-tomographer-in-discriminating-high-myopic-astigmatism-from-keratoconus
#38
JOURNAL ARTICLE
Ebenezer Zaabaar, Samuel Kyei, Maame Ama Amamoah Parkson Brew, Samuel Bert Boadi-Kusi, Frank Assiamah, Kofi Asiedu
The study aimed to evaluate and compare anterior segment parameters between keratoconic eyes and eyes with high myopic astigmatism using Pentacam Scheimpflug tomography. This was a retrospective cross-sectional study that included sixty keratoconic eyes (thirty-two persons) and seventy-three eyes (forty-six persons) with high myopic astigmatism with mean ages 24.72 ± 11.65years and 26.60 ± 10.69years, respectively. Twenty-three parameters from the topographic map and fifteen parameters from the Belin-Ambrosió enhanced ectasia display map of the printouts of a Scheimpflug principle-based Pentacam tomographer were evaluated for their diagnostic accuracy using Receiver Operating Characteristic (ROC) curve...
2021: PloS One
https://read.qxmd.com/read/34841930/detecting-subclinical-keratoconus-by-biomechanical-analysis-in-tomographically-regular-keratoconus-fellow-eyes
#39
JOURNAL ARTICLE
Victor A Augustin, Hyeck-Soo Son, Isabella Baur, Ling Zhao, Gerd U Auffarth, Ramin Khoramnia
PURPOSE: To analyze the tomographically non-affected second eyes of keratoconus patients using the Corvis ST to detect any biomechanical abnormalities or subclinical keratoconus. METHODS: In this retrospective, single-center, consecutive case series 244 eyes of 122 keratoconus patients were analyzed between November 2020 and February 2021. Fourteen fellow eyes fulfilled the inclusion criteria and showed no clinical or tomographic signs of keratoconus. Main outcome measures included best-corrected visual acuity, tomographic and biomechanical analyses using Scheimpflug imaging: Pentacam and Corvis ST (Oculus, Wetzlar, Germany)...
November 29, 2021: European Journal of Ophthalmology
https://read.qxmd.com/read/34759202/implications-of-diagnostic-drops-on-scheimpflug-tomography-the-proper-order-for-clinical-testing
#40
JOURNAL ARTICLE
Prema Padmanabhan, Michael W Belin, Rachapalle Reddi Sudhir, Deepa Mukundan, Hemalatha Chidambaram, Renato Ambrósio
PURPOSE: The purpose of this article was to study the impact of instillation of 1% fluorescein and mydriatics on measurements made by Scheimpflug imaging. METHODS: This was a cross-sectional study of patients who had measurements of corneal shape (maximum keratometry and best fit sphere of anterior and posterior corneal surfaces), pachymetry (at the pupil center, corneal apex, and thinnest location), and anterior chamber parameters (depth, volume, and angle of anterior chamber and corneal volume) using the Pentacam HR before and after the instillation of fluorescein and mydriatics...
August 1, 2022: Cornea
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