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https://www.readbyqxmd.com/read/28621948/insight-into-the-am-o-phase-equilibria-a-thermodynamic-study-coupling-high-temperature-xrd-and-calphad-modeling
#1
Enrica Epifano, Christine Guéneau, Renaud C Belin, Romain Vauchy, Florent Lebreton, Jean-Christophe Richaud, Alexis Joly, Christophe Valot, Philippe M Martin
In the frame of minor actinide transmutation, americium can be diluted in UO2 and (U, Pu)O2 fuels burned in fast neutron reactors. The first mandatory step to foresee the influence of Am on the in-reactor behavior of transmutation targets or fuel is to have fundamental knowledge of the Am-O binary system and, in particular, of the AmO2-x phase. In this study, we coupled HT-XRD (high-temperature X-ray diffraction) experiments with CALPHAD thermodynamic modeling to provide new insights into the structural properties and phase equilibria in the AmO2-x-AmO1...
June 16, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28586501/biomechanical-characterization-of-subclinical-keratoconus-without-topographic-or-tomographic-abnormalities
#2
Riccardo Vinciguerra, Renato Ambrósio, Cynthia J Roberts, Claudio Azzolini, Paolo Vinciguerra
PURPOSE: To present a case series of patients with subclinical keratoconus with normal topometric (anterior curvature) and tomographic findings in one eye who showed abnormalities detected by Corvis ST (Oculus Optikgeräte GmbH, Wetzlar, Germany) in vivo biomechanical assessment. METHODS: All patients had a complete ophthalmic examination, including the Corvis ST biomechanical measurements, optical tomography, and pachymetry with Pentacam (Oculus Optikgeräte GmbH), and Placido-based topography with either the Nidek (OPD III Nidek, Gamagori, Japan) or CSO platform (Costruzione Strumenti Oftalmici, Florence, Italy)...
June 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/28578858/long-chain-fatty-acids-lcfa-evolution-for-inhibition-forecasting-during-anaerobic-treatment-of-lipid-rich-wastes-case-of-milk-fed-veal-slaughterhouse-waste
#3
R Rodríguez-Méndez, Y Le Bihan, F Béline, P Lessard
A detailed study of a solid slaughterhouse waste (SHW) anaerobic treatment is presented. The waste used in this study is rich in lipids and proteins residue. Long chain fatty acids (LCFA), coming from the hydrolysis of lipids were inhibitory to anaerobic processes at different degrees. Acetogenesis and methanogenesis processes were mainly affected by inhibition whereas disintegration and hydrolysis processes did not seem to be affected by high LCFA concentrations. Nevertheless, because of the high energy content, this kind of waste is very suitable for anaerobic digestion but strict control of operating conditions is required to prevent inhibition...
June 1, 2017: Waste Management
https://www.readbyqxmd.com/read/28578744/a-corner-store-intervention-to-improve-access-to-fruits-and-vegetables-in-two-latino-communities
#4
Stephanie L Albert, Brent A Langellier, Mienah Z Sharif, Alec M Chan-Golston, Michael L Prelip, Rosa Elena Garcia, Deborah C Glik, Thomas R Belin, Ron Brookmeyer, Alexander N Ortega
OBJECTIVE: Investments have been made to alter the food environment of neighbourhoods that have a disproportionate number of unhealthy food venues. Corner store conversions are one strategy to increase access to fruits and vegetables (F&V). Although the literature shows modest success, the effectiveness of these interventions remains equivocal. The present paper reports on the evaluation of Proyecto MercadoFRESCO, a corner store conversion intervention in two Latino communities. DESIGN: A repeated cross-sectional design was employed...
June 5, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28576215/effect-of-dry-eye-on-scheimpflug-imaging-of-the-cornea-and-elevation-data
#5
Leyla Asena, Dilek D Altınörs, Şefik Cezairlioğlu, Sefer Ogün Bölük
OBJECTIVE: To evaluate the effect of dry eye on Scheimpflug imaging of the cornea and elevation data. DESIGN: Prospective observational study. PARTICIPANTS: Scheimpflug images of 50 patients with dry eye who were being tested for eligibility for corneal refractive surgery were screened. Twelve eyes of 12 patients with abnormal Belin/Ambrosio enhanced ectasia display (BAD) anterior elevation difference were included in the study. The patients had no history of contact lens wear or any other sign of ectasia...
June 2017: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/28559422/comparison-of-corneal-dynamic-parameters-and-tomographic-measurements-using-scheimpflug-imaging-in-keratoconus
#6
Tommy Cy Chan, Yu Meng Wang, Marco Yu, Vishal Jhanji
AIM: To compare the diagnostic ability of corneal tomography and corneal dynamic response measurements in normal and keratoconus eyes. METHODS: Consecutive patients with grade II-III keratoconus and age-matched normal subjects were recruited. Corneal imaging was performed using Pentacam (Oculus Optikgeräte, Wetzlar, Germany) and Corvis (Oculus Optikgeräte). A beta version of Corvis software was used with three additional parameters: maximal change of arc length, deformation amplitude (DA) ratio 1 and DA ratio 2...
May 30, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28553834/evidence-for-a-long-lasting-compulsive-alcohol-seeking-phenotype-in-rats
#7
Chiara Giuliano, Yolanda Peña-Oliver, Charles R Goodlett, Rudolf N Cardinal, Trevor W Robbins, Edward T Bullmore, David Belin, Barry J Everitt
Excessive drinking to intoxication is the major behavioral characteristic of those addicted to alcohol but it is not the only one. Indeed, those addicted to alcohol also crave alcoholic beverages and spend time and put much effort into compulsively seeking alcohol, before eventually drinking large amounts. Unlike this excessive drinking, for which treatments exist, compulsive alcohol seeking is therefore another key feature of the persistence of alcohol addiction since it leads to relapse and for which there are few effective treatments...
May 29, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28550642/post-heroin-dose-tissue-distribution-of-6-monoacetylmorphine-6-mam-with-maldi-imaging
#8
Belin G Teklezgi, Annapurna Pamreddy, Sooraj Baijnath, Nirmala D Gopal, Tricia Naicker, Hendrik G Kruger, Thavendran Govender
Heroin is an illicit opioid drug which is commonly abused and leads to dependence and addiction. Heroin is considered a pro-drug and is rapidly converted to its major active metabolite 6-monoacetylmorphine (6-MAM) which mediates euphoria and reward through the stimulation of opioid receptors in the brain. The aim of this study was to investigate the distribution and localization of 6-MAM in the healthy Sprague Dawley rat brain following intraperitoneal (i.p) administration of heroin (10 mg/kg), using matrix-assisted laser desorption/ionization mass spectrometric imaging (MALDI-MSI), in combination with quantification via liquid chromatography mass spectrometry (LC-MS/MS)...
May 26, 2017: Journal of Molecular Histology
https://www.readbyqxmd.com/read/28550286/ultrasensitive-multiplexed-immunoassay-of-autophagic-biomarkers-based-on-au-rgo-and-au-nanocages-amplifying-electrochemcial-signal
#9
Guannan Wang, Yankun Li, Jinlei Liu, Yajing Yuan, Zhaoliang Shen, Xifan Mei
A novel sandwich-assay electrochemical immunosensor for simultaneous determination of autophagic biomarkers was introduced for the first time, the gold-reduced grapheme oxide nanocomposite (Au/r-GO) set as a good conductive platform with super high specific area, and provided more binding sites for the both antibodies of Beclin-1 and LC3B-II. While Au nanocages (AuNCs) served as good conductive platform to encapsulate a large amount of redox probe and secondary antibodies for signal amplification, due to the abundant reactive oxygen functional groups on its surface...
May 26, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28548161/click-co-sandwich-terminated-dendrimers-as-polyhydride-reservoirs-and-micellar-templates
#10
Amalia Rapakousiou, Colette Belin, Lionel Salmon, Jaime Ruiz, Didier Astruc
Neutral click metallodendrimers with [Co(I)(η(4)-cyclopentadiene)(η(5)-cyclopentadienyl)] termini are synthesized by reduction of dendrimers with 9, 27 or 81 cobalticenium termini and serve as polyhydride reservoirs and reductants; for instance, they reduce proton sources to H2 and Au(III) to micellized capsules of gold nanoparticles.
June 6, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28540099/genetic-variations-and-mrna-expression-of-nrf2-in-parkinson-s-disease
#11
Caroline Ran, Karin Wirdefeldt, Lovisa Brodin, Mehrafarin Ramezani, Marie Westerlund, Fengqing Xiang, Anna Anvret, Thomas Willows, Olof Sydow, Anders Johansson, Dagmar Galter, Per Svenningsson, Andrea Carmine Belin
Nuclear factor erythroid 2-like 2 (NRF2) encodes a transcription factor regulating mechanisms of cellular protection and is activated by oxidative stress. NRF2 has therefore been hypothesized to confer protection against Parkinson's disease and so far an NRF2 haplotype has been reported to decrease the risk of developing disease and delay disease onset. Also NRF2 adopts a nuclear localization in Parkinson's disease, which is indicative of increased NRF2 activity. We have investigated the association between NRF2 and Parkinson's disease in a Swedish case-control material and whether NRF2 expression levels correlate with NRF2 genetic variants, disease, or disease onset...
2017: Parkinson's Disease
https://www.readbyqxmd.com/read/28533010/initial-investigation-of-the-corrosion-stability-of-craniofacial-implants
#12
Thamara Beline, Aljomar José Vechiato Filho, Alvin G Wee, Cortino Sukotjo, Daniela Micheline Dos Santos, Thaís Bianca Brandão, Valentim Adelino Ricardo Barão
STATEMENT OF PROBLEM: Although craniofacial implants have been used for retention of facial prostheses, failures are common. Titanium undergoes corrosion in the oral cavity, but the corrosion of craniofacial implants requires evaluation. PURPOSE: The purpose of this in vitro study was to investigate the corrosion stability of commercially pure titanium (CP Ti) exposed to simulated human perspiration at 2 different pH levels (5.5 and 8). MATERIAL AND METHODS: Fifteen titanium disks were divided into 3 groups (n=5 per group)...
May 20, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28499661/second-malignancies-after-permanent-implant-prostate-cancer-brachytherapy-a-single-institution-study-of-675%C3%A2-patients-treated-between-1999-and-2003
#13
J-M Cosset, L Belin, G Wakil, T Flam, N Thiounn, N Pierrat, D Pontvert, A Savignoni, L Chauveinc
PURPOSE: To analyse the rate of secondary malignancies observed in a series of 675 prostate cancer patients who underwent a permanent implant brachytherapy between 1999 and 2003, and to compare the incidence with the expected rate in a matched general French population. MATERIAL AND METHODS: The cohort included low-risk patients and a selection of "favourable-intermediate" risk patients. All patients were homogeneously treated using an intraoperative dynamic planning prostate brachytherapy technique, with loose 125-iodine seeds and a prescription dose of 145Gy...
May 2017: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
https://www.readbyqxmd.com/read/28466652/a-genetic-clock-variant-associated-with-cluster-headache-causing-increased-mrna-levels
#14
Carmen Fourier, Caroline Ran, Margret Zinnegger, Anne-Sofie Johansson, Christina Sjöstrand, Elisabet Waldenlind, Anna Steinberg, Andrea Carmine Belin
Background Cluster headache is characterized by recurrent unilateral headache attacks of severe intensity. One of the main features in a majority of patients is a striking rhythmicity of attacks. The CLOCK ( Circadian Locomotor Output Cycles Kaput) gene encodes a transcription factor that serves as a basic driving force for circadian rhythm in humans and is therefore particularly interesting as a candidate gene for cluster headache. Methods We performed an association study on a large Swedish cluster headache case-control sample (449 patients and 677 controls) screening for three single nucleotide polymorphisms (SNPs) in the CLOCK gene implicated in diurnal preference (rs1801260) or sleep duration (rs11932595 and rs12649507), respectively...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/28457476/mechanisms-underlying-methamphetamine-related-dental-disease
#15
Jason Clague, Thomas R Belin, Vivek Shetty
BACKGROUND: The authors clarified the causal mechanisms underlying the high prevalence of dental disease encountered in people who habitually use methamphetamine (meth). METHODS: Using a stratified sampling approach, the authors conducted comprehensive oral examinations and psychosocial assessments for 571 study participants who used meth. Three calibrated dentists, who used National Health and Nutrition Examination Survey (NHANES) protocols, characterized the study participants' dental disease...
June 2017: Journal of the American Dental Association
https://www.readbyqxmd.com/read/28449127/effects-of-emotional-valence-and-arousal-on-the-voice-perception-network
#16
Patricia E G Bestelmeyer, Sonja A Kotz, Pascal Belin
Several theories conceptualise emotions along two main dimensions: valence (a continuum from negative to positive) and arousal (a continuum that varies from low to high). These dimensions are typically treated as independent in many neuroimaging experiments, yet recent behavioural findings suggest that they are actually interdependent. This result has impact on neuroimaging design, analysis and theoretical development. We were interested in determining the extent of this interdependence both behaviourally and neuroanatomically, as well as teasing apart any activation that is specific to each dimension...
April 25, 2017: Social Cognitive and Affective Neuroscience
https://www.readbyqxmd.com/read/28387763/the-need-for-all-cataract-surgeons-to-run-a-regular-vitreous-loss-fire-drill
#17
D Lockington, M Belin, C N J McGhee
No abstract text is available yet for this article.
April 7, 2017: Eye
https://www.readbyqxmd.com/read/28378203/bidirectional-regulation-over-the-development-and-expression-of-loss-of-control-over-cocaine-intake-by-the-anterior-insula
#18
Jean-Yves Rotge, Paul J Cocker, Marie-Laure Daniel, Aude Belin-Rauscent, Barry J Everitt, David Belin
RATIONALE: Increasing evidence suggests that the anterior insular cortex (AIC) plays a major role in cocaine addiction, being implicated in both impaired insight and associated decision-making and also craving and relapse. However, the nature of the involvement of the insula in the development and maintenance of cocaine addiction remains unknown, thereby limiting our understanding of its causal role in addiction. We therefore investigated whether pre- and post-training bilateral lesions of the AIC differentially influenced the development and the expression of the escalation of cocaine self-administration during extended access to the drug...
May 2017: Psychopharmacology
https://www.readbyqxmd.com/read/28374807/sesamol-induces-human-hepatocellular-carcinoma-cells-apoptosis-by-impairing-mitochondrial-function-and-suppressing-autophagy
#19
Zhigang Liu, Bo Ren, Yihui Wang, Chen Zou, Qinglian Qiao, Zhijun Diao, Yashi Mi, Di Zhu, Xuebo Liu
Sesamol, a nutritional phenolic antioxidant compound enriched in sesame seeds, has been shown to have potential anticancer activities. This study aims at characterizing the antitumor efficacy of sesamol and unveiling the importance of mitochondria in sesamol-induced effects using a human hepatocellular carcinoma cell line, HepG2 cells. Results of this study showed that sesamol treatment suppressed colony formation, elicited S phase arrest during cell cycle progression, and induced both intrinsic and extrinsic apoptotic pathway in vitro with a dose-dependent manner...
April 4, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28365212/residues-in-the-glun1-c-terminal-domain-control-kinetics-and-pharmacology-of-glun1-glun3a-n-methyl-d-aspartate-receptors
#20
Kirstie A Cummings, Sophie Belin, Gabriela K Popescu
N-methyl-d-aspartate (NMDA) receptors assembled from GluN1 and GluN3 subunits are unique in that they form glycine-gated excitatory channels that are insensitive to glutamate and NMDA. Alternative splicing of the GluN1 subunit mRNA results in eight variants with regulated expression patterns and post-translational modifications. Here we investigate the role of residues in the GluN1 C-terminal alternatively spliced cassettes in receptor gating and modulation. We measured whole-cell currents from recombinant GluN1/GluN3A receptors expressed in HEK293 cells that differed in the sequence of their GluN1 C-terminal tail...
June 2017: Neuropharmacology
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