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https://www.readbyqxmd.com/read/27833723/the-frequency-distribution-of-celiac-autoantibodies-in-alopecia-areata
#1
Fatemeh Mokhtari, Tayebeh Panjehpour, Farahnaz Fatemi Naeini, Sayed Mohsen Hosseini, Mohammad Ali Nilforoushzadeh, Marzieh Matin
BACKGROUND: Alopecia areata (AA) is a noncicatricial (nonscarring) alopecia. The association between AA and celiac disease (CD) is debatable. Several studies declare the relationship between AA and CD as measurement of celiac autoantibodies (anti-gliadin IgA and anti-gliadin IgG), but a few studies consider anti-tissue transglutaminase IgA. The aim of this study was to evaluate the frequency distribution of celiac autoantibodies (all of them) in patients with AA compared with controls...
2016: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/27825568/osteoarticular-manifestations-of-celiac-disease-and-non-celiac-gluten-hypersensitivity
#2
Stéphanie Dos Santos, Frédéric Lioté
Celiac disease is a chronic inflammatory autoimmune enteropathy based disorder that is triggered by the ingestion of gluten in genetically susceptible individuals. The global prevalence of 1% to 2% represents only the tip of the iceberg. The diagnosis is confirmed by positive specific antibody, anti-transglutaminase or anti-endomysium, specific lesions of the small intestine and a response to strict gluten-free diet. The diagnosis is difficult and often delayed because the clinical variability is very large, ranging from digestive clinical presentation "classic" to "atypical" symptoms, often extra-intestinal, that are sometimes attributed to a concomitant disease or a complication...
November 4, 2016: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/27796452/development-and-optimisation-of-a-generic-micro-lc-esi-ms-method-for-the-qualitative-and-quantitative-determination-of-30-mer-toxic-gliadin-peptides-in-wheat-flour-for-food-analysis
#3
Bilgin Vatansever, Amalia Muñoz, Christoph L Klein, Knut Reinert
We sometimes see manufactured bakery products on the market which are labelled as being gluten free. Why is the content of such gluten proteins of importance for the fabrication of bakery industry and for the products? The gluten proteins represent up to 80 % of wheat proteins, and they are conventionally subdivided into gliadins and glutenins. Gliadins belong to the proline and glutamine-rich prolamin family. Its role in human gluten intolerance, as a consequence of its harmful effects, is well documented in the scientific literature...
October 28, 2016: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/27763541/properties-of-gluten-intolerance-gluten-structure-evolution-pathogenicity-and-detoxification-capabilities
#4
Anastasia V Balakireva, Andrey A Zamyatnin
Theterm gluten intolerance may refer to three types of human disorders: autoimmune celiac disease (CD), allergy to wheat and non-celiac gluten sensitivity (NCGS). Gluten is a mixture of prolamin proteins present mostly in wheat, but also in barley, rye and oat. Gluten can be subdivided into three major groups: S-rich, S-poor and high molecular weight proteins. Prolamins within the groups possess similar structures and properties. All gluten proteins are evolutionarily connected and share the same ancestral origin...
October 18, 2016: Nutrients
https://www.readbyqxmd.com/read/27735799/celiac-disease-in-patients-with-williams-beuren-syndrome
#5
Ercan Mıhçı, Banu Güzel Nur, Sibel Berker-Karaüzüm, Aygen Yılmaz, Reha Artan
Celiac disease is an autoimmune, gastrointestinal disorder characterized by intolerance to the dietary grain protein gluten. An increased prevalence of celiac disease has been reported in Down syndrome and Turner syndrome, but there has been only few previous reports with respect to the association of celiac disease in Williams-Beuren syndrome. The aim of this study was to evaluate the frequency of celiac disease in our 24 Williams-Beuren syndrome patients. Gastrointestinal problems and celiac disease symptoms of patients were noted...
November 2015: Turkish Journal of Pediatrics
https://www.readbyqxmd.com/read/27706458/prevalence-of-genetic-susceptibility-for-celiac-disease-in-blood-donors-in-s%C3%A3-o-paulo-brazil
#6
Janaína Guilhem Muniz, Vera Lucia Sdepanian, Ulysses Fagundes
Background: Celiac disease is a permanent intolerance induced by gluten, which is expressed by T-cell mediated enteropathy, and has a high prevalence in the general population. There is evidence of a strong genetic predisposition to celiac disease. Objective: To determine the prevalence of genetic markers HLA-DQ2 and HLA-DQ8 in blood donors from São Paulo and measure human recombinant tissue transglutaminase antibody IgA class in HLA-DQ2 and HLA-DQ8 positive donors...
October 2016: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/27699780/diet-and-headache-part-1
#7
Vincent T Martin, Brinder Vij
BACKGROUND: The role of diet in the management of the headache patient is a controversial topic in the headache field. OBJECTIVES: To review the evidence supporting the hypothesis that specific foods or ingredients within foods and beverages trigger attacks of headache and/or migraine and to discuss the use of elimination diets in the prevention of headache disorders METHODS: This represents part 1 of a narrative review of the role of diet in the prevention of migraine and other headache disorders...
October 2016: Headache
https://www.readbyqxmd.com/read/27620516/dental-and-oral-considerations-in-pediatric-celiac-disease
#8
Sara Karlin, Ellen Karlin, Timothy Meiller, Nasir Bashirelahi
Celiac disease (CD) is the world's most common genetic food intolerance disorder. Children with celiac disease cannot tolerate gluten, a storage protein in wheat, rye, and barley. The first recognizable symptom in children is often an oral manifestation, rather than the typical gastrointestinal symptoms. The purpose of this paper is to review the oral and dental manifestations of CD to help pediatric dentists identify and refer atypically symptomatic patients to their pediatricians.
2016: Journal of Dentistry for Children
https://www.readbyqxmd.com/read/27603917/structural-culinary-nutritional-and-anti-nutritional-properties-of-high-protein-gluten-free-100-legume-pasta
#9
Karima Laleg, Denis Cassan, Cécile Barron, Pichan Prabhasankar, Valérie Micard
Wheat pasta has a compact structure built by a gluten network entrapping starch granules resulting in a low glycemic index, but is nevertheless unsuitable for gluten-intolerant people. High protein gluten-free legume flours, rich in fibers, resistant starch and minerals are thus a good alternative for gluten-free pasta production. In this study, gluten-free pasta was produced exclusively from faba, lentil or black-gram flours. The relationship between their structure, their cooking and Rheological properties and their in-vitro starch digestion was analyzed and compared to cereal gluten-free commercial pasta...
2016: PloS One
https://www.readbyqxmd.com/read/27552857/alterations-in-diets-of-patients-with-nonceliac-gluten-sensitivity-compared-with-healthy-individuals
#10
Fabiana Zingone, Chiara Bartalini, Monica Siniscalchi, Monica Ruotolo, Cristina Bucci, Ivonne Morra, Paola Iovino, Carolina Ciacci
BACKGROUND & AIMS: There is evidence that food components beyond gluten cause symptoms in patients with gluten sensitivity without celiac disease (nonceliac gluten sensitivity [NCGS]). We investigated the diets and nutritional characteristics of patients with NCGS. METHODS: We performed a prospective observational study of 29 patients with NCGS seen at the outpatient clinic for celiac disease and other food intolerances of the University of Salerno in Italy from September 2015 through April 2016...
August 21, 2016: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/27547052/the-broad-spectrum-of-celiac-disease-and-gluten-sensitive-enteropathy
#11
REVIEW
Oana Mocan, Dan L Dumitraşcu
The celiac disease is an immune chronic condition with genetic transmission, caused by the intolerance to gluten. Gluten is a protein from cereals containing the following soluble proteins: gliadine, which is the most toxic, and the prolamins. The average prevalence is about 1% in USA and Europe, but high in Africa: 5.6% in West Sahara. In the pathogenesis several factors are involved: gluten as external trigger, genetic predisposition (HLA, MYO9B), viral infections, abnormal immune reaction to gluten. Severity is correlated with the number of intraepithelial lymphocytes, cryptic hyperplasia and villous atrophy, as well as with the length of intestinal involvement...
2016: Clujul Medical (1957)
https://www.readbyqxmd.com/read/27545437/anti-gm1-ganglioside-antibodies-neuron-specific-enolase-and-interleukin-10-concentrations-as-potential-markers-of-autonomic-nervous-system-impairment-in-celiac-disease-preliminary-findings
#12
Magdalena Przybylska-Feluś, Małgorzata Zwolińska-Wcisło, Agnieszka Piątek-Guziewicz, Agata Furgała, Kinga Sałapa, Tomasz Mach
INTRODUCTION    Celiac disease (CD) is an immune-mediated enteropathy related to permanent gluten intolerance with numerous clinical manifestations such as typical gastrointestinal symptoms as well as atypical and asymptomatic forms including neurological symptoms. Presence of neuron-specific enolase (NSE), interleukin 10 (IL-10) and anti-ganglioside antibodies have been demonstrated for several neurological conditions as well as immunological disorders with neurological manifestations.  OBJECTIVES    The aim of the study was to determine IL-10, NSE and anti-GM1 antibodies concentrations in the course of celiac disease and their correlation with changes in electrogastrography (EGG) and heart rate variability (HRV) recordings...
August 22, 2016: Polskie Archiwum Medycyny Wewnętrznej
https://www.readbyqxmd.com/read/27498299/gluten-intolerance-and-neurodevelopmental-disorders-is-nitric-oxide-the-common-biomarker-linking-these-conditions
#13
Keith Fluegge
Cruchet et al. attempt to tease out the myths and facts surrounding the growing popularity of certain dietary approaches in the management of neurodevelopmental disorders, like attention-deficit hyperactivity disorder (ADHD) and autism spectrum disorders (ASDs). The authors identify a particular exclusionary-type approach that seeks to eliminate dietary gluten. Although the relationship between celiac disease (CD) and ADHD/ASD is not well established, a repeated clinical feature noted in CD is the elevated levels of nitric oxide in serum and urine...
2016: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/27458507/association-between-celiac-disease-and-chronic-hepatitis-c
#14
REVIEW
Giovanni Casella, Davide Viganò, Carlo Romano Settanni, Olivia Morelli, Vincenzo Villanacci, Vittorio Baldini, Gabrio Bassotti
Celiac disease is characterized by a gluten-induced damage of the small bowel in sensitive individuals that may cause malabsorption. Non-intestinal inflammatory diseases may trigger immunologic gluten intolerance in susceptible people and the HCV virus may be considered as a suitable candidate. Interferon therapy could precipitate symptom onset in subjects with silent celiac disease. In fact, symptoms such as diarrhea, anemia, and weight loss may occur during interferon therapy and are associated with serological positivity of anti-tranglutaminase antibodies...
2016: Gastroenterology and Hepatology From Bed to Bench
https://www.readbyqxmd.com/read/27446825/celiac-disease-and-gluten-free-oats-a-canadian-position-based-on-a-literature-review
#15
REVIEW
Sébastien La Vieille, Olga M Pulido, Michael Abbott, Terence B Koerner, Samuel Godefroy
This paper provides an overview of the latest scientific data related to the safety of uncontaminated oats (<20 ppm of gluten) in the diet of individuals with celiac disease (CD). It updates the previous Health Canada position posted on the Health Canada website in 2007 and a related paper published in 2009. It considers a number of recent studies published between January 2008 and January 2015. While recognizing that a few people with celiac disease seem to be clinically intolerant to oats, this review concludes that oats uncontaminated by gluten-containing cereals (wheat, rye, and barley) can be safely ingested by most patients with celiac disease and that there is no conclusive evidence that the consumption of uncontaminated or specially produced oats containing no greater than 20 ppm gluten by patients with celiac disease should be limited to a specific daily amount...
2016: Canadian Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/27374565/protective-effects-of-id331-triticum-monococcum-gliadin-on-in-vitro-models-of-the-intestinal-epithelium
#16
Giuseppe Iacomino, Luigia Di Stasio, Olga Fierro, Gianluca Picariello, Antonella Venezia, Laura Gazza, Pasquale Ferranti, Gianfranco Mamone
A growing interest in developing new strategies for preventing coeliac disease has motivated efforts to identify cereals with null or reduced toxicity. In the current study, we investigate the biological effects of ID331 Triticum monococcum gliadin-derived peptides in human Caco-2 intestinal epithelial cells. Triticum aestivum gliadin derived peptides were employed as a positive control. The effects on epithelial permeability, zonulin release, viability, and cytoskeleton reorganization were investigated. Our findings confirmed that ID331 gliadin did not enhance permeability and did not induce zonulin release, cytotoxicity or cytoskeleton reorganization of Caco-2 cell monolayers...
December 1, 2016: Food Chemistry
https://www.readbyqxmd.com/read/27322560/celiac-disease-and-wheat-intolerance-syndrome-a-critical-update-and-reappraisal
#17
Hilary Jericho, Asaad Assiri, Stefano Guandalini
Since the first description of celiac disease (CeD) by Samuel Gee in 1888 and the later "miraculous discovery" that bread was responsible for this condition following World War II in Europe there has been an exponential growth of knowledge regarding CeD. However, just when we thought that we knew everything there was to know about it, the disease is offering new challenges, with its presentaton having significantly morphed over the years from cases of overt gastrointestinal symptoms, malnutrition, and atrophic villi on duodenal biopsies to that of largely extra-intestinal, subtle or mild symptoms...
June 17, 2016: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/27216895/immunogenetic-pathogenesis-of-celiac-disease-and-non-celiac-gluten-sensitivity
#18
REVIEW
Celia Escudero-Hernández, Amado Salvador Peña, David Bernardo
Celiac disease is the most common oral intolerance in Western countries. It results from an immune response towards gluten proteins from certain cereals in genetically predisposed individuals (HLA-DQ2 and/or HLA-DQ8). Its pathogenesis involves the adaptive (HLA molecules, transglutaminase 2, dendritic cells, and CD4(+) T-cells) and the innate immunity with an IL-15-mediated response elicited in the intraepithelial compartment. At present, the only treatment is a permanent strict gluten-free diet (GFD). Multidisciplinary studies have provided a deeper insight of the genetic and immunological factors and their interaction with the microbiota in the pathogenesis of the disease...
July 2016: Current Gastroenterology Reports
https://www.readbyqxmd.com/read/27215624/-food-allergy-and-intolerance-distinction-definitions-and-delimitation
#19
Jörg Kleine-Tebbe, Anja Waßmann-Otto, Hubert Mönnikes
Immunologically mediated hypersensitivity to foods is defined as food allergy, mainly due to immunglobulins of class E (IgE) triggering immediate reactions (type I hypersensitivity) with possible involvement of mucosa, skin, airways, intestinal tract, and the vascular system. Primary food allergy is based on (early) IgE sensitization against animal (e. g., cow's milk, hen's eggs) or plant proteins (e. g. peanut, hazelnut or wheat). In the case of secondary food allergies, IgE against pollen proteins (e...
June 2016: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
https://www.readbyqxmd.com/read/27173757/defecation-into-clothing-without-forewarning-and-mean-radiation-dose-to-bowel-and-anal-sphincter-among-gynecological-cancer-survivors
#20
Helena Lind, Eleftheria Alevronta, Gunnar Steineck, Ann-Charlotte Waldenström, Tommy Nyberg, Caroline Olsson, Ulrica Wilderäng, Gail Dunberger, Massoud Al-Abany, Elisabeth Åvall-Lundqvist
BACKGROUND: To analyze the relationship between mean radiation dose to the bowels and the anal-sphincter and occurrence of 'defecation into clothing without forewarning', a specific and serious fecal incontinence symptom after gynecological radiotherapy. Additional potential risk factors associated with the symptom are explored. MATERIAL AND METHODS: Data were collected for 519 eligible gynecological cancer survivors, treated with pelvic radiotherapy, with a median follow-up of 5...
May 13, 2016: Acta Oncologica
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