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Paulo boggio stimulation

Michele Devido Dos Santos, Vitor Breseghello Cavenaghi, Ana Paula Machado Goyano Mac-Kay, Vitor Serafim, Alexandre Venturi, Dennis Quangvinh Truong, Yu Huang, Paulo Sérgio Boggio, Felipe Fregni, Marcel Simis, Marom Bikson, Rubens José Gagliardi
CONTEXT AND OBJECTIVE: Patients undergoing the same neuromodulation protocol may present different responses. Computational models may help in understanding such differences. The aims of this study were, firstly, to compare the performance of aphasic patients in naming tasks before and after one session of transcranial direct current stimulation (tDCS), transcranial magnetic stimulation (TMS) and sham, and analyze the results between these neuromodulation techniques; and secondly, through computational model on the cortex and surrounding tissues, to assess current flow distribution and responses among patients who received tDCS and presented different levels of results from naming tasks...
September 2017: São Paulo Medical Journal, Revista Paulista de Medicina
Nathalia Ishikawa Baptista, Mirella Manfredi, Paulo Sérgio Boggio
In this study, we investigated whether the ERP responses observed during a verbal irony comprehension task might represent the cortical manifestation of the Medial Prefrontal Cortex (MPFC) activity. We performed a tDCS-EEG study in which we analyzed the effects of tDCS polarities (anode, cathode, sham) over the MPFC during a verbal irony task. We presented visual short stories portraying everyday situations followed by written statements in either an ironic or literal condition, whose meaning was referred to in the previous context...
July 17, 2017: Social Neuroscience
Mirella Manfredi, Alice Mado Proverbio, Ana Paula Gonçalves Donate, Sofia Macarini Gonçalves Vieira, William Edgar Comfort, Mariana De Araújo Andreoli, Paulo Sérgio Boggio
The superior temporal gyrus (STG) has been found to play a crucial role in the recognition of actions and facial expressions and may, therefore, be critical for the processing of humorous information. Here we investigated whether tDCS application to the STG would modulate the ability to recognize and appreciate the comic element in serious and comedic situations of misfortune. To this aim, the effects of different types of tDCS stimulation on the STG were analyzed during a task in which the participants were instructed to categorize various misfortunate situations as "comic" or "not comic"...
June 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
Marom Bikson, Pnina Grossman, Chris Thomas, Adantchede Louis Zannou, Jimmy Jiang, Tatheer Adnan, Antonios P Mourdoukoutas, Greg Kronberg, Dennis Truong, Paulo Boggio, André R Brunoni, Leigh Charvet, Felipe Fregni, Brita Fritsch, Bernadette Gillick, Roy H Hamilton, Benjamin M Hampstead, Ryan Jankord, Adam Kirton, Helena Knotkova, David Liebetanz, Anli Liu, Colleen Loo, Michael A Nitsche, Janine Reis, Jessica D Richardson, Alexander Rotenberg, Peter E Turkeltaub, Adam J Woods
This review updates and consolidates evidence on the safety of transcranial Direct Current Stimulation (tDCS). Safety is here operationally defined by, and limited to, the absence of evidence for a Serious Adverse Effect, the criteria for which are rigorously defined. This review adopts an evidence-based approach, based on an aggregation of experience from human trials, taking care not to confuse speculation on potential hazards or lack of data to refute such speculation with evidence for risk. Safety data from animal tests for tissue damage are reviewed with systematic consideration of translation to humans...
September 2016: Brain Stimulation
Suellen M Andrade, Natanael A Santos, Bernardino Fernández-Calvo, Paulo S Boggio, Eliane A Oliveira, José J Ferreira, Amanda Sobreira, Felipe Morgan, Germana Medeiros, Gyovanna S Cavalcanti, Ingrid D Gadelha, Jader Duarte, Joercia Marrocos, Michele A Silva, Thatiana Rufino, Sanmy R Nóbrega
BACKGROUND: Traditional treatment for motor impairment after stroke includes medication and physical rehabilitation. The transcranial direct current stimulation associated with a standard physical therapy program may be an effective therapeutic alternative for these patients. METHODS: This study is a sham-controlled, double-blind, randomized clinical trial aiming to evaluate the efficacy of transcranial direct current stimulation in activities of daily living and motor function post subacute stroke...
January 28, 2016: Trials
Marie-Anne Vanderhasselt, Rudi De Raedt, Victoria Namur, Leandro C L Valiengo, Paulo A Lotufo, Isabela M Bensenor, Chris Baeken, Paulo S Boggio, Andre R Brunoni
Emotional Context Insensitivity (ECI) is a psychological feature observed in depressed patients characterized by a decreased emotional reactivity when presented to positive- and negative valence-loaded stimuli. Given that fronto-cingulate-limbic circuits are implicated in abnormal reactivity to valence-loaded stimuli, neurocognitive treatments engaging the prefrontal cortex may be able to modulate this emotional blunting observed in MDD. Therefore, our goal was to evaluate emotional reactivity in depressed patients before and after a combination of neurocognitive interventions that engage the prefrontal cortex (cognitive control training and/or transcranial direct current stimulation)...
January 15, 2016: Journal of Affective Disorders
Suellen Marinho Andrade, Bernardino Fernández-Calvo, Paulo Sérgio Boggio, Eliane Araújo de Oliveira, Lilze Franklim Gomes, José Eudes Gomes Pinheiro Júnior, Rafaela Martins Rodrigues, Natália Leandro de Almeida, Gioconda Marla de Siqueira Moreira, Nelson Torro Alves
BACKGROUND: Stroke patients may present severe cognitive impairments, primarily related to executive functions. Transcranial direct current stimulation has shown promising results, with neuromodulatory and neuroplastic effects. This study is a double-blind, sham-controlled clinical trial aiming to compare the long-term effects of stimulation in two different cognitive regions after a stroke. METHODS/DESIGN: Sixty patients who suffer from chronic strokes will be randomized into one of four groups: dorsolateral prefrontal cortex, cingulo-opercular network, motor primary cortex and sham stimulation...
September 29, 2015: Trials
Paulo S Boggio, Manish K Asthana, Thiago L Costa, Cláudia A Valasek, Ana A C Osório
Being socially connected directly impacts our basic needs and survival. People with deficits in social cognition might exhibit abnormal behaviors and face many challenges in our highly social-dependent world. These challenges and limitations are associated with a substantial economical and subjective impact. As many conditions where social cognition is affected are highly prevalent, more treatments have to be developed. Based on recent research, we review studies where non-invasive neuromodulatory techniques have been used to promote Social Plasticity in developmental disorders...
2015: Frontiers in Neuroscience
Thiago L Costa, Olivia M Lapenta, Paulo S Boggio, Dora F Ventura
Transcranial direct current stimulation (tDCS) is a non-invasive neuromodulatory technique with increasing popularity in the fields of basic research and rehabilitation. It is an affordable and safe procedure that is beginning to be used in the clinic, and is a tool with potential to contribute to the understanding of neural mechanisms in the fields of psychology, neuroscience, and medical research. This review presents examples of investigations in the fields of perception, basic sensory processes, and sensory rehabilitation that employed tDCS...
August 2015: Attention, Perception & Psychophysics
Gabriel G Rêgo, Olívia M Lapenta, Lucas M Marques, Thiago L Costa, Jorge Leite, Sandra Carvalho, Óscar F Gonçalves, André R Brunoni, Felipe Fregni, Paulo S Boggio
The dorsolateral prefrontal cortex (DLPFC) is involved in the cognitive appraisal and modulation of the pain experience. In this sham-controlled study, with healthy volunteers, we used bi-hemispheric transcranial direct current stimulation (tDCS) over the DLPFC to assess emotional reactions elicited by pain observation. Left-cathodal/right-anodal tDCS decreased valence and arousal evaluations compared to other tDCS conditions. Compared to sham condition, both left-cathodal/right-anodal and left-anodal/right-cathodal tDCS decreased hostility, sadness and self-pain perception...
May 6, 2015: Neuroscience Letters
Thiago L Costa, Mirella Gualtieri, Mirella T S Barboni, Rafael K Katayama, Paulo S Boggio, Dora F Ventura
Recent research suggested that transcranial direct current stimulation (tDCS) can affect visual processing and that it can be useful in visual rehabilitation. Nevertheless, there are still few investigations on the subject. tDCS selectivity and the extent of its outcomes on visual perception are still to be assessed. Here, we investigate whether central and peripheral visual fields are equally affected by tDCS. We also tried to reproduce a previous work that has evaluated tDCS effects on the central visual field only (Kraft et al...
May 2015: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
Thiago L Costa, Russell D Hamer, Balázs V Nagy, Mirella T S Barboni, Mirella Gualtieri, Paulo S Boggio, Dora F Ventura
Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique that can modulate cortical activity. Nonetheless, information regarding its functional specificity and the extent by which visual performance can be modulated is still lacking. Here, we used vision as model to address if it differentially affects different cell groups in the stimulated area. We applied tDCS to the occiput and performed a series of visual tests in a sham-controlled repeated-measures design. Achromatic contrast sensitivity was assessed psychophysically during tDCS, with tasks designed to target specific spatial frequency (SF) channels, inferred ON, OFF channels and inferred magnocellular and parvocellular pathways of the visual system...
April 2015: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
Thiago L Costa, Marcelo F Costa, Adsson Magalhães, Gabriel G Rêgo, Balázs V Nagy, Paulo S Boggio, Dora F Ventura
Recent research suggests that V1 plays an active role in the judgment of size and distance. Nevertheless, no research has been performed using direct brain stimulation to address this issue. We used transcranial direct-current stimulation (tDCS) to directly modulate the early stages of cortical visual processing while measuring size and distance perception with a psychophysical scaling method of magnitude estimation in a repeated-measures design. The subjects randomly received anodal, cathodal, and sham tDCS in separate sessions starting with size or distance judgment tasks...
February 19, 2015: Neuroscience Letters
Sandra Carvalho, Paulo S Boggio, Óscar F Gonçalves, Ana Rita Vigário, Marisa Faria, Soraia Silva, Gabriel Gaudencio do Rego, Felipe Fregni, Jorge Leite
BACKGROUND: It has been already shown that delivering tDCS that are spaced by an interval alters its impact on motor plasticity. These effects can be explained, based on metaplasticity in which a previous modification of activity in a neuronal network can change the effects of subsequent interventions in the same network. But to date there is limited data assessing metaplasticity effects in cognitive functioning. OBJECTIVES: The aim of this study was to test several tDCS-based metaplasticity protocols in working memory (WM), by studying the impact of various interstimulation intervals in the performance of a 3-back task...
March 2015: Brain Stimulation
Marie-Anne Vanderhasselt, Rudi De Raedt, Victoria Namur, Paulo A Lotufo, Isabela M Bensenor, Paulo S Boggio, Andre R Brunoni
Rumination is a cognitive-affective thinking style that plays a key role in the onset and maintenance of depression. Recently, it was shown that clinically depressed patients who received a neurocognitive training - involving two weeks of repetitive cognitive control exercises that necessitate prefrontal engagement - are more able to control over ruminative negative thoughts than patients who only received treatment as usual. Transcranial Direct Current Stimulation (tDCS) is a biological technique that can directly modulate prefrontal excitability via the manipulation of neural membrane potentials...
March 3, 2015: Progress in Neuro-psychopharmacology & Biological Psychiatry
Fabiana Guarienti, Wolnei Caumo, Pedro Shiozawa, Quirino Cordeiro, Paulo S Boggio, Isabela M Benseñor, Paulo A Lotufo, Marom Bikson, André R Brunoni
OBJECTIVES: Transcranial direct current stimulation (tDCS)-induced erythema (skin reddening) has been described as an adverse effect that can harm blinding integrity in sham-controlled designs. To tackle this issue, we investigated whether the use of topical pretreatments could decrease erythema and other adverse effects associated with tDCS. MATERIALS AND METHODS: Thirty healthy volunteers were recruited, and four interventions were applied 30 min prior to tDCS in a Latin square design: placebo, ketoprofen 2%, hydroxyzine 1%, and lidocaine 5%...
June 2015: Neuromodulation: Journal of the International Neuromodulation Society
Lucas Murrins Marques, Olivia Morgan Lapenta, Lotfi B Merabet, Nadia Bolognini, Paulo Sérgio Boggio
In the so-called McGurk illusion, when the synchronized presentation of the visual stimulus /ga/ is paired with the auditory stimulus /ba/, people in general hear it as /da/. Multisensory integration processing underlying this illusion seems to occur within the Superior Temporal Sulcus (STS). Herein, we present evidence demonstrating that bilateral cathodal transcranial direct current stimulation (tDCS) of this area can decrease the McGurk illusion-type responses. Additionally, we show that the manipulation of this audio-visual integrated output occurs irrespective of the number of eye-fixations on the mouth of the speaker...
2014: Frontiers in Human Neuroscience
Olivia Morgan Lapenta, Karina Di Sierve, Elizeu Coutinho de Macedo, Felipe Fregni, Paulo Sérgio Boggio
Food craving can be defined as the "urge to eat a specific food". Previous findings suggest impairment of inhibitory control, specifically a regulatory deficit in the lateral prefrontal circuitry that is associated with a compulsion for food. As demonstrated by three previous studies, bilateral transcranial direct current stimulation (tDCS) of the dorsolateral prefrontal cortex (DLPFC) (anode right/cathode left) reduces food craving and caloric intake. We designed the present study to evaluate the neural mechanisms that underlie these effects...
December 2014: Appetite
Shirley Fecteau, Sara Agosta, Antoine Hone-Blanchet, Felipe Fregni, Paulo Boggio, Domenic Ciraulo, Alvaro Pascual-Leone
BACKGROUND: Most tobacco smokers who wish to quit fail to reach their goal. One important, insufficiently emphasized aspect of addiction relates to the decision-making system, often characterized by dysfunctional cognitive control and a powerful drive for reward. Recent proof-of-principle studies indicate that transcranial direct current stimulation (tDCS) over the dorsolateral prefrontal cortex (DLPFC) can transiently modulate processes involved in decision-making, and reduce substance intake and craving for various addictions...
July 1, 2014: Drug and Alcohol Dependence
Michele Devido Santos, Rubens José Gagliardi, Ana Paula Machado Goyano Mac-Kay, Paulo Sergio Boggio, Roberta Lianza, Felipe Fregni
CONTEXT AND OBJECTIVE: Previous animal and human studies have shown that transcranial direct current stimulation can induce significant and lasting neuroplasticity and may improve language recovery in patients with aphasia. The objective of the study was to describe a cohort of patients with aphasia after stroke who were treated with transcranial direct current stimulation. DESIGN AND SETTING: Prospective cohort study developed in a public university hospital. METHODS: Nineteen patients with chronic aphasia received 10 transcranial direct current stimulation sessions lasting 20 minutes each on consecutive days, using a current of 2 mA...
2013: São Paulo Medical Journal, Revista Paulista de Medicina
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