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https://www.readbyqxmd.com/read/28920966/-prevention-of-cardiovascular-diseases-prophylactic-program-in-a-selected-enterprise
#1
Jadwiga Siedlecka, Elżbieta Gadzicka, Agata Szyjkowska, Patryk Siedlecki, Wiesław Szymczak, Teresa Makowiec-Dąbrowska, Alicja Bortkiewicz
BACKGROUND: In Poland cardiovascular diseases (CVD), classified as work-related diseases, are responsible for 25% of disability and cause 50% of all deaths, including 26.9% of deaths in people aged under 65 years. The aim of the study was to analyze employee expectations regarding CVD- oriented prophylactic activities in the selected enterprise. MATERIAL AND METHODS: A questionnaire, developed for this study, consists of: socio-demographic data, job characteristics, occupational factors, and questions about the respondents' expectations concerning the prevention program...
September 18, 2017: Medycyna Pracy
https://www.readbyqxmd.com/read/28919494/shoulder-injury-in-water-polo-a-systematic-review-of-incidence-and-intrinsic-risk-factors
#2
REVIEW
Andrea H Miller, Kerrie Evans, Roger Adams, Gordon Waddington, Jeremy Witchalls
OBJECTIVES: Water polo is a popular water-based contact sport that involves swimming, throwing and defending. Cumulatively, these repetitive overhead activities are thought to increase the risk of shoulder injury and, subsequently to affect players' physical conditioning as well as team performance. The purpose of this review was to examine available evidence relating to shoulder injury rates and risk factors for shoulder injury in water polo. DESIGN: Systematic review METHODS: CINAHL, AUSPORT, Pubmed, Pedro and SPORTDiscus databases were searched for original research papers using the predefined terms ("water polo") AND (shoulder OR glenohumeral* OR arm OR "upper limb")...
August 31, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/28914562/the-effect-of-regular-aquatic-exercise-on-blood-pressure-a-meta-analysis-of-randomized-controlled-trials
#3
Yutaka Igarashi, Yoshie Nogami
Background No meta-analysis has examined the effect of regular aquatic exercise on blood pressure. The purpose of this study was to perform a meta-analysis to evaluate the effects of regular aquatic exercise on blood pressure. Design A meta-analysis of randomized controlled trials. Methods Databases were searched for literature published up to April 2017. The randomized controlled trials analysed involved healthy adults, an intervention group that only performed aquatic exercise and a control group that did not exercise, no other intervention, and trials indicated mean systolic blood pressure or diastolic blood pressure...
January 1, 2017: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/28913953/marine-depth-use-of-sea-trout-salmo-trutta-in-fjord-areas-of-central-norway
#4
S H Eldøy, J G Davidsen, E B Thorstad, F G Whoriskey, K Aarestrup, T F Naesje, L Rønning, A D Sjursen, A H Rikardsen, J V Arnekleiv
The vertical behaviour of 44 veteran sea trout Salmo trutta (275-580 mm) in different marine fjord habitats (estuary, pelagic, near shore with and without steep cliffs) was documented during May-February by acoustic telemetry. The swimming depth of S. trutta was influenced by habitat, time of day (day v. night), season, seawater temperature and the body length at the time of tagging. Mean swimming depth during May-September was 1·7 m (individual means ranged from 0·4 to 6·4 m). Hence, S. trutta were generally surface oriented, but performed dives down to 24 m...
September 15, 2017: Journal of Fish Biology
https://www.readbyqxmd.com/read/28911850/activation-of-indoleamine-2-3-dioxygenase-pathway-by-olanzapine-augments-antidepressant-effects-of-venlafaxine-in-mice
#5
Jaya Thomas, Razia Khanam, Divya Vohora
Recent clinical studies report antipsychotics as a better option to augment the action of antidepressants in treatment resistant cases. However, the proper mechanisms underlying the antidepressant effect of antipsychotics is still not clear. Indolamine 2, 3 dioxygenase (IDO) pathway is considered to be an important pathway in pro-inflammatory cytokine associated stress-induced depression. The present study investigated the antidepressant effect of venlafaxine, olanzapine and their combinations in chronic forced-swim stress-induced depression in mice...
August 31, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28911611/antifatigue-and-increasing-exercise-performance-of-actinidia-arguta-crude-alkaloids-in-mice
#6
Yangyang Liu, Changjiang Liu
Actinidia arguta (Siebold et Zucc.) Planch. ex. Miq. is one of the most recently domesticated fruit species with increasing commercial production worldwide. It is a well-known traditional Chinese medicine and is used to reduce blood glucose and treat atopic dermatitis. In addition, it possesses antioxidant, anticancer, and antiallergic properties. In this study, we investigated the physical antifatigue and exercise performance effects of A. arguta crude alkaloids (AACA) extracted with 70% ethanol. Four groups of male Kunming mice (n = 16) were orally administered AACA at doses of 0 mg/kg/d (vehicle), 50 mg/kg/d (AACA-50), 100 mg/kg/d (AACA-100), or 200 mg/kg/d (AACA-200) for 28 days...
October 2016: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/28904314/effects-of-tannin-fluoride-and-milk-fluoride-mixture-on-human-enamel-erosion-from-inappropriately-chlorinated-pool-water
#7
Sumalee Boonviriya, Sissada Tannukit, Suwanna Jitpukdeebodintra
This in vitro study aimed to investigate the efficacy of tannin-fluoride and milk-fluoride mixtures on human enamel erosion after exposure to inappropriately chlorinated pool water. Enamel specimens were immersed in swimming pool water (pH 2.7) for 30 min and in each test reagent for 4 min once a day for 60 consecutive days (group I: control, group II: tannin-fluoride, group III: milk-fluoride, group IV: tannin-fluoride before and milk-fluoride after erosive challenge, and group V: milk containing tannin-fluoride before and after erosive exposure)...
2017: Journal of Oral Science
https://www.readbyqxmd.com/read/28893665/does-aerobic-capacity-predict-the-spatial-position-of-individuals-within-schools-in-juvenile-qingbo-spinibarbus-sinensis
#8
Ling-Qing Zeng, Cheng Fu, Shi-Jian Fu
Schooling behavior is an adaptive trait of important biological and ecological significance in fish species. However, the question of how aerobic capacity and environmental factors (i.e., food and water velocity) affect the spatial positioning within fish schools has received little attention. Our study measured the aerobic capacity-as indicated by standard metabolic rate (SMR), maximum metabolic rate (MMR) and aerobic scope (AS)-and swimming performance of juvenile qingbo (Spinibarbus sinensis) and filmed their schooling behavior in a swim tunnel under both a control treatment and food stimulus treatment at three water velocities (20, 30 and 40cms(-1))...
September 9, 2017: Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology
https://www.readbyqxmd.com/read/28893591/neurosteroid-dehydroepiandrosterone-improves-active-avoidance-retrieval-and-induces-antidepressant-like-behavior-in-rats
#9
Janko Samardzic, Boris Hencic, Jasna Jancic, Dragana Jadzic, Milos Djuric, Dragan I Obradovic, Dubravka Svob Strac
Various studies reported beneficial effects of dehydroepiandrosterone (DHEA) and its sulphate (DHEAS), the neurosteroids involved in various brain functions, on synaptic plasticity, neuronal survival, memory, learning and behavior. This study aimed to investigate the behavioral profile of acute DHEA treatment by using active avoidance (AA) task, primarily predictive of the effects on the retrieval-based learning, and by applying forced swim test (FST), for assessment of antidepressant-like potential. Adult male Wistar rats received intraperitoneal injections of either DHEA (2, 10, 20mg/kg) or solvent, 30min prior to testing...
September 8, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28890521/effect-of-burdock-extract-on-physical-performance-and-physiological-fatigue-in-mice
#10
Wen-Chyuan Chen, Yi-Ju Hsu, Mon-Chien Lee, Hua Shuai Li, Chun-Sheng Ho, Chi-Chang Huang, Fu-An Chen
Burdock (BD) is a common vegetable with many pharmacological properties. However, few studies have examined the effect of BD on exercise performance and physical fatigue. We aimed to evaluate the potential beneficial effects of BD on fatigue and ergogenic functions following physical challenge in mice. METHODS: Male ICR mice were divided into four groups to receive either vehicle, or BD at 348.5, 697 or 1,742.5 mg/kg/day, by daily oral gavage for 4 weeks. Exercise performance and fatigue were evaluated from forelimb grip strength, exhaustive swimming time, and post-exercise levels of physical fatigue-related biomarkers serum lactate, ammonia, glucose, and creatine kinase (CK)...
September 11, 2017: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/28890389/motor-function-deficits-in-the-12-month-old-female-5xfad-mouse-model-of-alzheimer-s-disease
#11
T P O'Leary, A Robertson, P H Chipman, V F Rafuse, R E Brown
Motor problems occur early in some patients with Alzheimer's disease (AD) and as the disease progresses many patients develop motor dysfunction. Motor dysfunction has been reported in some mouse models of AD, including the 5xFAD mouse, thus this model may be particularly useful for studying motor dysfunction in AD. In order to determine the extent of motor dysfunction in these mice, we tested 11-13 month old female 5xFAD and wildtype (WT) control mice in a battery of motor behaviour tasks. The 5xFAD mice showed hind limb clasping, weighed less and had slower righting reflexes than WT mice...
September 7, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28889975/consistent-individual-differences-drive-collective-behavior-and-group-functioning-of-schooling-fish
#12
Jolle W Jolles, Neeltje J Boogert, Vivek H Sridhar, Iain D Couzin, Andrea Manica
The ubiquity of consistent inter-individual differences in behavior ("animal personalities") [1, 2] suggests that they might play a fundamental role in driving the movements and functioning of animal groups [3, 4], including their collective decision-making, foraging performance, and predator avoidance. Despite increasing evidence that highlights their importance [5-16], we still lack a unified mechanistic framework to explain and to predict how consistent inter-individual differences may drive collective behavior...
September 1, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28888226/modulation-of-hippocampal-neuronal-activity-by-so-ochim-tang-gamibang-in-mice-subjected-to-chronic-restraint-stress
#13
Hwa Chul Shin, Jae Ho Lee, Ki Joong Kim, Hyun Jin Shin, Jeong June Choi, Chan Yong Lee, Uk Namgung, In Chul Jung
BACKGROUND: So-ochim-tang-gamibang (SOCG) is a decoction formula which has been used to improve mental activity in traditional Korean medicine. The present study was performed to evaluate whether the treatment of SOCG was involved in activating hippocampal neurons in mice which were subjected to chronic restraint stress (CRS). METHODS: Mice were subjected to CRS for 2 weeks to induce depressive-like behaviors. SOCG was orally administered for the same period. mRNA expression in the hippocampus was analyzed by RT-PCR...
September 9, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28888125/interactive-effects-of-microcystin-and-ammonia-on-the-reproductive-performance-and-phenotypic-traits-of-the-rotifer-brachionus-calyciflorus
#14
Ye Liang, Xuxin Lu, Yuanqi Min, Lulu Liu, Jiaxin Yang
Elevated microcystin-LR (MC-LR) and ammonia (NH3-N) concentrations co-occur during the degradation of Microcystis blooms, and are toxic to aquatic organisms. The freshwater rotifer, Brachionus calyciflorus, was exposed to mixtures of MC-LR (0, 10, 30, and 100µgL(-1)) and NH3-N (0, 270, and 540µgL(-1)) to assess the combined effects of the two toxicants on reproductive performance and phenotype traits. Single solutions of MC-LR (100µgL(-1)) and NH3-N (540µgL(-1)) had negative effects on rotifer reproductive timing and fecundity...
September 6, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28888088/possible-modulation-of-ppar-%C3%AE-cascade-against-depression-caused-by-neuropathic-pain-in-rats
#15
Shanky Garg, Vishwajit Ravindra Deshmukh, Pranav Prasoon
BACKGROUND: Sciatic nerve ligation causes neuropathic pain with chronic constriction injury (CCI). However, there is no published report on the effect of pioglitazone as an antidepressant in the treatment of depression induced by neuropathic pain with CCI in rats. The aim of this study was to evaluate the effect of pioglitazone as an antidepressant by targeting oxidative stress by the peripheral neuropathic pain model using the CCI of the sciatic nerve. METHODS: Behavioral studies were carried out to measure thermal hyperalgesia and cold allodynia as markers of neuropathic pain and force swim test for depression...
September 9, 2017: Journal of Basic and Clinical Physiology and Pharmacology
https://www.readbyqxmd.com/read/28886235/in-the-search-for-a-lead-structure-among-series-of-potent-and-selective-hydantoin-5-ht7-r-agents-the-drug-likeness-in-vitro-study
#16
Gniewomir Latacz, Annamaria Lubelska, Magdalena Jastrzębska-Więsek, Anna Partyka, Andrzej Sobiło, Agnieszka Olejarz, Katarzyna Kucwaj-Brysz, Grzegorz Satała, Andrzej J Bojarski, Anna Wesołowska, Katarzyna Kieć-Kononowicz, Jadwiga Handzlik
Since the year 1993, when 5-HT7 receptor (5-HT7 R) was discovered, there is no selective 5-HT7 R ligand introduced to the pharmaceutical market. One out of the main reasons disqualifying the 5-HT7 R ligands are weak drugability properties, including metabolic instability or low permeability. This study is focused on the search of a lead compound by "drug-likeness" estimation of the first series of selective and potent 5-HT7 R ligands among 5-(4-fluorophenyl)-3-(2-hydroxy-3-(4-aryl-piperazin-1-yl)propyl)-5-methyl-imidazolidine-2,4-dione derivatives (11-16)...
September 8, 2017: Chemical Biology & Drug Design
https://www.readbyqxmd.com/read/28885646/relationship-between-clinical-results-of-total-hip-replacement-and-postoperative-activities-including-weeding-and-snow-shovelling
#17
Hiroaki Kijima, Shin Yamada, Natsuo Konishi, Hitoshi Kubota, Hiroshi Tazawa, Takayuki Tani, Norio Suzuki, Keiji Kamo, Yoshihiko Okudera, Ken Sasaki, Tetsuya Kawano, Naohisa Miyakoshi, Yoichi Shimada
INTRODUCTION: Weeding or snow shovelling is indispensable for life in farm villages of northern countries. Clarifying the relationships between the degrees of these activities after total hip replacement (THR) and the clinical results of THR may enable us to predict the results of THR for high-level activity patients. The relationships between work activities after THR and the results were investigated. METHODS: The subjects were 95 post-THR patients, who consulted 6 hospitals in August 2012...
September 7, 2017: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/28882191/effects-of-sustained-i-c-v-infusion-of-lupus-csf-and-autoantibodies-on-behavioral-phenotype-and-neuronal-calcium-signaling
#18
Minesh Kapadia, Dunja Bijelić, Hui Zhao, Donglai Ma, Ljudmila Stojanovich, Milena Milošević, Pavle Andjus, Boris Šakić
Systemic lupus erythematosus (SLE) is a potentially fatal autoimmune disease that is often accompanied by brain atrophy and diverse neuropsychiatric manifestations of unknown origin. More recently, it was observed that cerebrospinal fluid (CSF) from patients and lupus-prone mice can be neurotoxic and that acute administration of specific brain-reactive autoantibodies (BRAs) can induce deficits in isolated behavioral tasks. Given the chronic and complex nature of CNS SLE, the current study examines broad behavioral performance and neuronal Ca(2+) signaling in mice receiving a sustained infusion of cerebrospinal fluid (CSF) from CNS SLE patients and putative BRAs (anti-NR2A, anti-ribosomal P, and anti-α-tubulin)...
September 7, 2017: Acta Neuropathologica Communications
https://www.readbyqxmd.com/read/28880242/synthesis-and-antidepressant-activity-profile-of-some-novel-benzothiazole-derivatives
#19
Ümide Demir Özkay, Ceren Kaya, Ulviye Acar Çevik, Özgür Devrim Can
Within the scope of our new antidepressant drug development efforts, in this study, we synthesized eight novel benzothiazole derivatives 3a-3h. The chemical structures of the synthesized compounds were elucidated by spectroscopic methods. Test compounds were administered orally at a dose of 40 mg/kg to mice 24, 5 and 1 h before performing tail suspension, modified forced swimming, and activity cage tests. The obtained results showed that compounds 3c, 3d, 3f-3h reduced the immobility time of mice as assessed in the tail suspension test...
September 7, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28875366/saikosaponin-d-relieves-unpredictable-chronic-mild-stress-induced-depressive-like-behavior-in-rats-involvement-of-hpa-axis-and-hippocampal-neurogenesis
#20
Hong-Yan Li, Ying-Hua Zhao, Min-Jie Zeng, Fang Fang, Min Li, Ting-Ting Qin, Lu-Yu Ye, Hong-Wei Li, Rong Qu, Shi-Ping Ma
RATIONALE: Saikosaponin D (SSD), a major bioactive component isolated from Radix Bupleuri, has been reported to exert neuroprotective properties. OBJECTIVES: The present study was designed to investigate the anti-depressant-like effects and the potential mechanisms of SSD. METHODS: Behavioural tests including sucrose preference test (SPT), open field test (OFT) and forced swim test (FST) were performed to study the antidepressant-like effects of SSD...
September 5, 2017: Psychopharmacology
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