keyword
MENU ▼
Read by QxMD icon Read
search

Respiratory distress

keyword
https://www.readbyqxmd.com/read/29933169/six-subphenotypes-in-septic-shock-latent-class-analysis-of-the-prowess-shock-study
#1
Bengt Gårdlund, Natalia O Dmitrieva, Carl F Pieper, Simon Finfer, John C Marshall, B Taylor Thompson
PURPOSE: Septic shock is a highly heterogeneous condition which is part of the challenge in its diagnosis and treatment. In this study we aim to identify clinically relevant subphenotypes of septic shock using a novel statistic al approach. METHODS: Baseline patient data from a large global clinical trial of septic shock (n = 1696) was analysed using latent class analysis (LCA). This approach allowed investigators to identify subgroups in a heterogeneous population by estimating a categorical latent variable that detects relatively homogeneous subgroups within a complex phenomenon...
June 8, 2018: Journal of Critical Care
https://www.readbyqxmd.com/read/29931538/alk5-runx1-signaling-mediated-by-extracellular-vesicles-promotes-vascular-repair-in-acute-respiratory-distress-syndrome
#2
Trushil Shah, Shanshan Qin, Mona Vashi, Dan N Predescu, Niranjan Jeganathan, Cristina Bardita, Balaji Ganesh, Salvatore diBartolo, Louis F Fogg, Robert A Balk, Sanda A Predescu
BACKGROUND: Pulmonary endothelial cells' (ECs) injury and apoptotic death are necessary and sufficient for the pathogenesis of the acute respiratory distress syndrome (ARDS), regardless of epithelial damage. Interaction of dysfunctional ECs with circulatory extracellular vesicles (EVs) holds therapeutic promise in ARDS. However, the presence in the blood of long-term ARDS survivors of EVs with a distinct phenotype compared to the EVs of non-surviving patients is not reported. With a multidisciplinary translational approach, we studied EVs from the blood of 33 patients with moderate-to-severe ARDS...
June 22, 2018: Clinical and Translational Medicine
https://www.readbyqxmd.com/read/29930881/an-unusual-neonatal-presentation-of-scimitar-syndrome
#3
Ahmad Abdul Aziz, Sumesh Thomas, David Lautner, Essa Hamadan Al Awad
Scimitar syndrome is characterized by partial or total anomalous pulmonary venous return from the right lung along with pulmonary hypoplasia. We present a case of a 37 weeks' gestation male infant with antenatal ultrasound findings of suspected partial anomalous pulmonary venous return (PAPVR) and coarctation of the aorta. The newborn presented with respiratory distress, a chest X-ray and chest computed tomography (CT) angiogram confirmed the diagnosis of scimitar syndrome. The combination of scimitar syndrome with aortic coarctation is extremely rare with only a few cases previously reported...
April 2018: American Journal of Perinatology Reports
https://www.readbyqxmd.com/read/29928958/is-drowning-a-mere-matter-of-resuscitation
#4
David Szpilman, Rafael de Barros Oliveira, Onir Mocellin, Jonathon Webber
International data severely underestimates actual drowning numbers. Almost all victims are able to help themselves or are rescued in time. This study aims to report the occurrence of Drowning Chain of Survival actions and resuscitations needed in a fully operational lifeguard service. METHODOLOGY: Data was collected from Dec-2009 to Mar-2015 by lifeguards at a 6km-long beach in Brazil. The Drowning Chain of Survival links were summarized into 3 main action-response sections: Prevention; rescue; and provide care...
June 18, 2018: Resuscitation
https://www.readbyqxmd.com/read/29928949/impaired-local-translation-of-%C3%AE-actin-mrna-in-ighmbp2-deficient-motoneurons-implications-for-spinal-muscular-atrophy-with-respiratory-distress-smard1
#5
Verena Surrey, Caren Zöller, Alicia Andrea Lork, Mehri Moradi, Stefanie Balk, Benjamin Dombert, Lena Saal-Bauernschubert, Michael Briese, Silke Appenzeller, Utz Fischer, Sibylle Jablonka
Spinal muscular atrophy with respiratory distress type 1 (SMARD1) is a fatal motoneuron disorder in children with unknown etiology. The disease is caused by mutations in the IGHMBP2 gene, encoding a Super Family 1 (SF1)-type RNA/DNA helicase. IGHMBP2 is a cytosolic protein that binds to ribosomes and polysomes, suggesting a role in mRNA metabolism. Here we performed morphological and functional analyses of isolated Ighmbp2 deficient motoneurons to address the question whether the SMARD1 phenotype results from de-regulation of protein biosynthesis...
June 18, 2018: Neuroscience
https://www.readbyqxmd.com/read/29926908/intensive-care-doctors-preferences-for-arterial-oxygen-tension-levels-in-mechanically-ventilated-patients
#6
O L Schjørring, A P Toft-Petersen, K H Kusk, P Mouncey, E E Sørensen, P Berezowicz, M H Bestle, H-H Bülow, H Bundgaard, S Christensen, S A Iversen, I Kirkeby-Garstad, K B Krarup, M Kruse, J H Laake, L Liboriussen, R L Laebel, M Okkonen, L M Poulsen, L Russell, F Sjövall, K Sunde, E Søreide, T Waldau, A R Walli, A Perner, J Wetterslev, B S Rasmussen
BACKGROUND: Oxygen is liberally administered in intensive care units (ICUs). Nevertheless, ICU doctors' preferences for supplementing oxygen are inadequately described. The aim was to identify ICU doctors' preferences for arterial oxygenation levels in mechanically ventilated adult ICU patients. METHODS: In April to August 2016, an online multiple-choice 17-part-questionnaire was distributed to 1080 ICU doctors in seven Northern European countries. Repeated reminder e-mails were sent...
June 21, 2018: Acta Anaesthesiologica Scandinavica
https://www.readbyqxmd.com/read/29926474/neonatal-interventions-for-preventing-cerebral-palsy-an-overview-of-cochrane-systematic-reviews
#7
REVIEW
Emily Shepherd, Rehana A Salam, Philippa Middleton, Shanshan Han, Maria Makrides, Sarah McIntyre, Nadia Badawi, Caroline A Crowther
BACKGROUND: Cerebral palsy is an umbrella term that encompasses disorders of movement and posture attributed to non-progressive disturbances occurring in the developing foetal or infant brain. As there are diverse risk factors and aetiologies, no one strategy will prevent cerebral palsy. Therefore, there is a need to systematically consider all potentially relevant interventions for prevention. OBJECTIVES: PrimaryTo summarise the evidence from Cochrane Systematic Reviews regarding effects of neonatal interventions for preventing cerebral palsy (reducing cerebral palsy risk)...
June 20, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29925137/-advances-of-hepatocyte-growth-factor-in-treatment-of-acute-respiratory-distress-syndrome
#8
S S Meng, Z H Lu, F M Guo
No abstract text is available yet for this article.
June 1, 2018: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/29924305/telocytes-promote-vegf-expression-and-alleviate-ventilator-induced-lung-injury-in-mice
#9
Ruihua Ma, Pinwen Wu, Qiqing Shi, Dongli Song, Hao Fang
Mechanical ventilation (MV) is an important procedure for the treatment of patients with acute lung injury or acute respiratory distress syndrome in a clinical setting; however, MV can lead to severe complications, including ventilator-induced lung injury (VILI). Telocytes (TCs) can promote tissue repair following injury in the heart, kidneys, and other organs. The aim of this study was to investigate the role of TCs in VILI in mice and the associated mechanisms. By using in vivo studies in mice and in vitro studies in cells, we demonstrated that an airway injection of TCs can reduce the pulmonary inflammatory response and improve the lung function in mice with VILI and promote the proliferation of pulmonary vascular endothelial cells...
June 19, 2018: Acta Biochimica et Biophysica Sinica
https://www.readbyqxmd.com/read/29923937/pulmonary-functions-in-children-ventilated-for-acute-hypoxemic-respiratory-failure
#10
Stanzen Chakdour, Pankaj C Vaidya, Suresh Kumar Angurana, Jayashree Muralidharan, Meenu Singh, Sunit C Singhi
OBJECTIVE: To assess pulmonary functions of children who received mechanical ventilation for acute hypoxemic respiratory failure. DESIGN: Longitudinal study. SETTING: PICU and Pediatric Pulmonology Clinic of a tertiary care teaching hospital in North India. PATIENTS: All children, 5-12 years old, ventilated for acute hypoxemic respiratory failure in PICU from July 2012 to June 2013 and survived. INTERVENTIONS: The baseline admission variables recorded were as follows: age, sex, duration of illness, primary diagnosis at admission, Pediatric Risk of Mortality III score, lung injury score, mechanical ventilation parameters, oxygenation indices, and duration of PICU stay...
June 19, 2018: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/29923087/apparent-acetaminophen-toxicity-in-a-patient-with-transaldolase-deficiency
#11
Jasmine Lee-Barber, Taylor E English, Jacquelyn F Britton, Nara Sobreira, Jason Goldstein, David Valle, Hans Tomas Bjornsson
Transaldolase deficiency (MIM#: 606003) is a rare autosomal recessive defect in the pentose phosphate pathway. Affected individuals are at risk for progressive liver failure and hepatocarcinoma. In the transaldolase-deficient mouse model (Taldo1 -/- ), these hepatic complications are accentuated by oxidative stress related to acetaminophen administration. We report a 13-month-old transaldolase-deficient male who developed mild liver failure after receiving standard doses of acetaminophen during a febrile respiratory syncytial virus infection...
June 20, 2018: JIMD Reports
https://www.readbyqxmd.com/read/29922788/photobiomodulation-prevents-dna-fragmentation-of-alveolar-epithelial-cells-and-alters-the-mrna-levels-of-caspase-3-and-bcl-2-genes-in-acute-lung-injury
#12
Luiz Philippe da Silva Sergio, Andrezza Maria Côrtes Thomé, Larissa Alexsandra da Silva Neto Trajano, Andre Luiz Mencalha, Adenilson de Souza da Fonseca, Flávia de Paoli
Acute respiratory distress syndrome (ARDS) and acute lung injury (ALI) are defined as pulmonary inflammation that could occur from sepsis and lead to pulmonary permeability and alveolar edema making them life-threatening diseases. Photobiomodulation (PBM) properties have been widely described in the literature in several inflammatory diseases; although the mechanisms of action are not always clear, this could be a possible treatment for ARDS/ALI. Thus, the aim of this study was to evaluate the mRNA levels from caspase-3 and BCL-2 genes and DNA fragmentation in lung tissue from Wistar rats affected by ALI and subjected to photobiomodulation by exposure to a low power infrared laser (808 nm; 100 mW; 3...
June 20, 2018: Photochemical & Photobiological Sciences
https://www.readbyqxmd.com/read/29922736/nasopharyngeal-airway-aspiration-an-uncommon-cause-of-sudden-respiratory-distress-in-hospitalized-patients
#13
Kosar Hussain, Sara Hussain, Jawed Abubaker, Raees Ahmed
An elderly, bed ridden patient with a history of stroke was admitted for management of aspiration pneumonia. Two days after insertion of a nasopharyngeal airway, sudden respiratory distress prompted further investigations which led to the eventual diagnosis and removal of the nasopharyngeal airway that had been aspirated. The device was removed under conscious sedation with fiber optic bronchoscopy.
June 2018: Turkish Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29920481/locally-advanced-cervical-cancer-is-a-trimodality-treatment-a-safe-and-effective-approach
#14
Domenica Lorusso, Fabio Martinelli, Giuseppa Maltese, Caterina Fontanella, Ilaria Sabatucci, Antonino Ditto, Mauro Signorelli, Giorgio Bogani, Stefano Lepori, Elisa Tripodi, Brigida Pappalardi, Cono Scaffa, Annamaria Cerrotta, Francesco Rapagliesi
BACKGROUND: Chemoradiotherapy (CRT) is the standard of care for locally advanced cervical cancer (LACC). Pre-treatment lymph nodes (LN) assessment may have an important therapeutic role. CRT followed by adjuvant chemotherapy increased progression free survival (PFS) and overall survival (OS). Our study evaluated the feasibility and the effectiveness of a trimodality strategy in patients with LACC and positive LN. METHODS: Consecutive patients with LACC treated at the National Cancer Institute of Milan were enrolled...
June 19, 2018: Oncology
https://www.readbyqxmd.com/read/29920152/selective-management-of-multiple-bronchopleural-fistulae-in-a-pediatric-patient-on-extracorporeal-membrane-oxygenation-a-multidisciplinary-approach
#15
Cory N Criss, Ryan Barbaro, Kristy Ann Bauman, Odetola Folafoluwa, Ranjith Vellody, Marcus D Jarboe
INTRODUCTION: This case highlights the successful utilization of a multidisciplinary approach to numerous bilateral bronchopleural fistulae (BPF) using minimally invasive techniques. In this study, we present a previously healthy 14-year-old male hospitalized with 2009 H1N1 influenza and methicillin-resistant Staphylococcus aureus coinfection complicated by severe acute respiratory distress syndrome and multifocal necrotizing pneumonia, with significant lung tissue damage requiring prolonged extracorporeal membrane oxygenation (ECMO) support...
June 19, 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29916449/antinuclear-antibodies-in-scrub-typhus-transient-occurrence-during-acute-illness
#16
Maria Koshy, John Mathew, Reginald Alex, John Antony Jude, Ravikar Ralph, Thambu David Sudarsanam, Sowmya Sathyendra, J Visalakshi, John Victor Peter
Background & objectives: The pathological hallmark of scrub typhus infection is focal or disseminated vasculitis. As with other infections, antinuclear antibodies (ANA) have been previously described in scrub typhus. However, the underlying mechanisms and implications of this immunological phenomenon is not well understood. In the present work it was assessed whether ANA is associated with illness severity and outcomes. Methods: In this prospective study spanning one year, patients fulfilling the diagnostic criteria for scrub typhus were recruited...
January 2018: Journal of Vector Borne Diseases
https://www.readbyqxmd.com/read/29916441/epidemiology-drug-resistance-and-pathophysiology-of-plasmodium-vivax-malaria
#17
REVIEW
Kiran K Dayananda, Rajeshwara N Achur, D Channe Gowda
Malaria, caused by the protozoan parasites of the genus Plasmodium, is a major health problem in many countries of the world. Five parasite species namely, Plasmodium falciparum, P. vivax, P. malariae, P. ovale, and P. knowlesi, cause malaria in humans. Of these, P. falciparum and P. vivax are the most prevalent and account for the majority of the global malaria cases. In most areas of Africa, P. vivax infection is essentially absent because of the inherited lack of Duffy antigen receptor for chemokines on the surface of red blood cells that is involved in the parasite invasion of erythrocytes...
January 2018: Journal of Vector Borne Diseases
https://www.readbyqxmd.com/read/29915854/perinatal-and-neonatal-morbidity-among-infants-of-diabetic-mothers-at-a-university-hospital-in-central-saudi-arabia
#18
Abdulrahman M Al-Nemri, Fahd Alsohime, Asfaq H Shaik, Ghasan A El-Hissi, Mohammed I Al-Agha, Nada F Al-Abdulkarim, Sarar Mohamed
OBJECTIVES: To determine the perinatal and neonatal morbidity related to diabetes associated with pregnancy. METHODS: This is a prospective cohort study conducted at a tertiary university hospital in Central Saudi Arabia. All neonates born to mothers with pregnancy associated diabetes between July 2014 and June 2015 were recruited for the purpose of this study. Infants born at 23 weeks or less, infants who died within 3 hours of delivery, twins, and unbooked pregnant ladies were excluded from the study...
June 2018: Saudi Medical Journal
https://www.readbyqxmd.com/read/29914880/antibiotic-prescribing-for-acute-respiratory-tract-infections-in-primary-care-an-updated-and-expanded-meta-ethnography
#19
Evi Germeni, Julia Frost, Ruth Garside, Morwenna Rogers, Jose M Valderas, Nicky Britten
BACKGROUND: Reducing unnecessary prescribing remains a key priority for tackling the global rise of antibiotic-resistant infections. AIM: The authors sought to update a 2011 qualitative synthesis of GPs' experiences of antibiotic prescribing for acute respiratory tract infections (ARTIs), including their views of interventions aimed at more prudent prescribing. They expanded the original scope to encompass all primary care professionals (PCPs) who can prescribe or dispense antibiotics for ARTIs (for example, nurses and pharmacists)...
June 18, 2018: British Journal of General Practice: the Journal of the Royal College of General Practitioners
https://www.readbyqxmd.com/read/29914404/significantly-different-clinical-features-between-hypertriglyceridemia-and-biliary-acute-pancreatitis-a-retrospective-study-of-730-patients-from-a-tertiary-center
#20
Xiaoyao Li, Lu Ke, Jie Dong, Bo Ye, Lei Meng, Wenjian Mao, Qi Yang, Weiqin Li, Jieshou Li
BACKGROUND: Unlike western world, gallstones and hypertriglyceridemia (HTG) are among the first two etiologies of acute pancreatitis (AP) in China. But yet, detailed differences in clinical features and outcomes between hypertriglyceridemia and biliary acute pancreatitis have not been well described. METHODS: This retrospective study enrolled 730 acute pancreatitis patients from July 1, 2013 to October 1, 2016 in Jinling Hospital. The causes of the study patients were defined according to specific diagnostic criteria...
June 19, 2018: BMC Gastroenterology
keyword
keyword
6883
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"