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Mark j Mannis cornea

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https://www.readbyqxmd.com/read/26555583/single-pass-microkeratome-system-for-eye-bank-dsaek-tissue-preparation-is-stromal-bed-thickness-predictable-and-reproducible
#1
Mazen Y Choulakian, Jennifer Y Li, Samuel Ramos, Mark J Mannis
PURPOSE: To evaluate the predictability and reproducibility of stromal bed thickness for single-pass donor Descemet stripping automated endothelial keratoplasty (DSAEK) tissue preparation, using the ML7 Microkeratome Donor Cornea System (Med-logics Inc, Athens, TX). METHODS: In this retrospective chart review of 256 consecutive corneal tissue preparations for DSAEK surgery, from June 2013 to August 2014, tissue thicknesses were divided into 3 groups, depending on surgeon preference: <91 μm (group A), 90 to 120 μm (group B), and 120 to 160 μm (group C)...
January 2016: Cornea
https://www.readbyqxmd.com/read/25752331/in-vivo-ocular-imaging-of-the-cornea-of-the-normal-female-laboratory-beagle-using-confocal-microscopy
#2
Ann R Strom, Dennis E Cortés, Sara M Thomasy, Philip H Kass, Mark J Mannis, Christopher J Murphy
OBJECTIVE: To obtain normative data for the normal laboratory beagle cornea using high-resolution in vivo confocal microscopy (IVCM). ANIMALS STUDIED: Sixteen eyes of eight healthy young female intact beagles. PROCEDURES: The central cornea was imaged using IVCM. Mixed effects linear regression was used for statistical analysis. RESULTS: in vivo confocal microscopy allowed detailed visualization and quantification of epithelial cells (superficial epithelial cell diameter: 43...
January 2016: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/25676065/in-vivo-evaluation-of-the-cornea-and-conjunctiva-of-the-normal-laboratory-beagle-using-time-and-fourier-domain-optical-coherence-tomography-and-ultrasound-pachymetry
#3
Ann R Strom, Dennis E Cortés, Carol A Rasmussen, Sara M Thomasy, Kim McIntyre, Shwu-Fei Lee, Philip H Kass, Mark J Mannis, Christopher J Murphy
OBJECTIVE: To obtain normative data for the canine cornea and conjunctiva using high-resolution time- and Fourier-domain optical coherence tomography (TD-OCT and FD-OCT) and ultrasound pachymetry (USP). ANIMALS: One hundred sixty-eight eyes of 133 healthy young intact laboratory beagles. PROCEDURES: The cornea and conjunctiva of 16 eyes of 8 healthy young intact female beagles were imaged using FD-OCT. Corneal thickness was measured with FD-OCT and USP, while corneal epithelial thickness and conjunctival epithelial thickness were measured with FD-OCT...
January 2016: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/25322173/factors-associated-with-corneal-graft-survival-in-the-cornea-donor-study
#4
RANDOMIZED CONTROLLED TRIAL
Alan Sugar, Robin L Gal, Craig Kollman, Dan Raghinaru, Mariya Dontchev, Christopher R Croasdale, Robert S Feder, Edward J Holland, Jonathan H Lass, Jonathan I Macy, Mark J Mannis, Patricia W Smith, Sarkis H Soukiasian, Roy W Beck
IMPORTANCE: The Cornea Donor Study (CDS) showed that donor age is not a factor in survival of most penetrating keratoplasties for endothelial disease. Secondary analyses confirm the importance of surgical indication and presence of glaucoma in outcomes at 10 years. OBJECTIVE: To assess the relationship between donor and recipient factors and corneal graft survival in the CDS. DESIGN, SETTING, AND PARTICIPANTS: Multicenter prospective, double-masked, controlled clinical trial conducted at 80 clinical sites...
March 2015: JAMA Ophthalmology
https://www.readbyqxmd.com/read/25119961/corneal-graft-rejection-10-years-after-penetrating-keratoplasty-in-the-cornea-donor-study
#5
Steven P Dunn, Robin L Gal, Craig Kollman, Dan Raghinaru, Mariya Dontchev, Christopher L Blanton, Edward J Holland, Jonathan H Lass, Kenneth R Kenyon, Mark J Mannis, Shahzad I Mian, Christopher J Rapuano, Walter J Stark, Roy W Beck
PURPOSE: The aim of this study was to assess the effect of donor and recipient factors on corneal allograft rejection and evaluate whether a rejection event was associated with graft failure. METHODS: One thousand ninety subjects undergoing penetrating keratoplasty for a moderate risk condition (principally Fuchs dystrophy or pseudophakic corneal edema) were followed for up to 12 years. Associations of baseline recipient and donor factors with the occurrence of a rejection event were assessed in univariate and multivariate proportional hazards models...
October 2014: Cornea
https://www.readbyqxmd.com/read/25000141/professor-dr-med-oskar-fehr-the-fate-of-an-outstanding-german-jewish-ophthalmologist-an-early-contributor-to-cornea-and-external-disease
#6
Walter Lisch, Mark J Mannis
PURPOSE: The aim of this study was to recount the immense and abrupt change in the private and professional life of a prominent German-Jewish ophthalmologist in the transition from democracy to dictatorship in Germany during the first half of the 20th century. METHODS: This involves a Retrospective analysis of Fehr's clinical and scientific work as the first assistant of Julius Hirschberg's world-famous eye clinic in Berlin; evaluation of Fehr's successful tenure as a chair of Virchow's Eye Hospital; the catastrophic influence of Hitler's seizure of power on the private and professional lives of German-Jewish physicians; and an analysis of Fehr's personal and professional will to continue the practice of medicine in England...
August 2014: Cornea
https://www.readbyqxmd.com/read/24999101/interfacial-phenomena-and-the-ocular-surface
#7
REVIEW
Bernardo Yañez-Soto, Mark J Mannis, Ivan R Schwab, Jennifer Y Li, Brian C Leonard, Nicholas L Abbott, Christopher J Murphy
Ocular surface disorders, such as dry eye disease, ocular rosacea, and allergic conjunctivitis, are a heterogeneous group of diseases that require an interdisciplinary approach to establish underlying causes and develop effective therapeutic strategies. These diverse disorders share a common thread in that they involve direct changes in ocular surface chemistry as well as the rheological properties of the tear film and topographical attributes of the cellular elements of the ocular surface. Knowledge of these properties is crucial to understand the formation and stability of the preocular tear film...
July 2014: Ocular Surface
https://www.readbyqxmd.com/read/24246826/donor-age-and-factors-related-to-endothelial-cell-loss-10-years-after-penetrating-keratoplasty-specular-microscopy-ancillary-study
#8
RANDOMIZED CONTROLLED TRIAL
Jonathan H Lass, Beth Ann Benetz, Robin L Gal, Craig Kollman, Dan Raghinaru, Mariya Dontchev, Mark J Mannis, Edward J Holland, Christopher Chow, Kristen McCoy, Francis W Price, Alan Sugar, David D Verdier, Roy W Beck
OBJECTIVE: To examine the effect of donor age and other perioperative factors on long-term endothelial cell loss after penetrating keratoplasty (PKP). DESIGN: Multicenter, prospective, double-masked clinical trial. PARTICIPANTS: We included 176 participants from the Cornea Donor Study cohort who had not experienced graft failure ≥ 10 years after PKP for a moderate risk condition (principally Fuchs' dystrophy or pseudophakic/aphakic corneal edema)...
December 2013: Ophthalmology
https://www.readbyqxmd.com/read/24246825/the-effect-of-donor-age-on-penetrating-keratoplasty-for-endothelial-disease-graft-survival-after-10-years-in-the-cornea-donor-study
#9
RANDOMIZED CONTROLLED TRIAL
Mark J Mannis, Edward J Holland, Robin L Gal, Mariya Dontchev, Craig Kollman, Dan Raghinaru, Steven P Dunn, Robert L Schultze, David D Verdier, Jonathan H Lass, Irving M Raber, Joel Sugar, Mark S Gorovoy, Alan Sugar, R Doyle Stulting, Monty M Montoya, Jeffrey G Penta, Beth Ann Benetz, Roy W Beck
OBJECTIVE: To determine whether the 10-year success rate of penetrating keratoplasty for corneal endothelial disorders is associated with donor age. DESIGN: Multicenter, prospective, double-masked clinical trial. PARTICIPANTS: A total of 1090 participants undergoing penetrating keratoplasty at 80 sites for Fuchs' dystrophy (62%), pseudophakic/aphakic corneal edema (34%), or another corneal endothelial disorder (4%) and followed for up to 12 years...
December 2013: Ophthalmology
https://www.readbyqxmd.com/read/24145635/evaluation-of-microbial-flora-in-eyes-with-a-boston-type-1-keratoprosthesis
#10
Samuel H Lee, Mark J Mannis, Brett Shapiro, Jennifer Y Li, Christopher Polage, Wayne Smith
PURPOSE: To evaluate the microbial flora of eyes with a Boston Keratoprosthesis (K-Pro). METHODS: A prospective study was performed for 17 eyes of 15 patients who underwent a K-Pro implantation between September 2005 and June 2011. Preoperative diagnoses included failed corneal grafts, limbal stem cell deficiency, chemical burns, and Stevens-Johnson Syndrome. The patients used topical antibiotics after their surgery including a fluoroquinolone, polymyxin-trimethoprim, vancomycin, or a combination of the 3...
December 2013: Cornea
https://www.readbyqxmd.com/read/24001528/lessons-in-corneal-structure-and-mechanics-to-guide-the-corneal-surgeon
#11
EDITORIAL
James V Jester, Christopher J Murphy, Moritz Winkler, Jan P G Bergmanson, Donald Brown, Roger F Steinert, Mark J Mannis
No abstract text is available yet for this article.
September 2013: Ophthalmology
https://www.readbyqxmd.com/read/23928949/epithelial-downgrowth-after-penetrating-keratoplasty-imaging-by-high-resolution-optical-coherence-tomography-and-in-vivo-confocal-microscopy
#12
Michael C Chen, Dennis E Cortés, George Harocopos, Mark J Mannis
PURPOSE: To report the clinical utility of high-resolution anterior segment optical coherence tomography (AS-OCT) combined with in vivo confocal microscopy (IVCM) to diagnose and follow the effectiveness of treatment of 2 cases of epithelial downgrowth after penetrating keratoplasty. METHODS: A retrospective case review was performed on 2 eyes of 2 patients with a history of multiple penetrating keratoplasties that developed epithelial downgrowth 4 and 6 months after the most recent penetrating graft...
November 2013: Cornea
https://www.readbyqxmd.com/read/23591146/high-resolution-spectral-domain-anterior-segment-optical-coherence-tomography-in-type-1-boston-keratoprosthesis
#13
Brett L Shapiro, Dennis E Cortés, Eric K Chin, Jennifer Y Li, John S Werner, Ellen Redenbo, Mark J Mannis
PURPOSE: To report the results of imaging using high-resolution, Fourier domain anterior segment optical coherence tomography (AS-OCT) to evaluate patients with a type 1 Boston Keratoprosthesis (KPro). METHODS: We performed a retrospective comparative study of patients in whom we implanted the Boston KPro. A total of 26 eyes of 23 patients from the Cornea Service at the University of California Davis Eye Center were included. Subjects were evaluated with the Spectralis AS-OCT (Heidelberg Engineering GmbH)...
July 2013: Cornea
https://www.readbyqxmd.com/read/23538623/anterior-segment-oct-and-confocal-microscopy-findings-in-atypical-corneal-intraepithelial-neoplasia
#14
Eric K Chin, Dennis E Cortés, Alexander Lam, Mark J Mannis
PURPOSE: To report a case of biopsy-proven corneal intraepithelial neoplasia (CIN) diagnosed and followed clinically using high-resolution anterior segment optical coherence tomography (AS-OCT) and in vivo confocal microscopy (IVCM). METHODS: Observational case report. RESULTS: A 57-year-old man presented with decreased vision in the right eye for 2 months before presentation. His best-corrected visual acuity was 20/70 in the affected eye, and the slit-lamp examination revealed superficial opacification of the anterior cornea originating from the temporal limbus with a "leopard-spot" pattern more centrally...
June 2013: Cornea
https://www.readbyqxmd.com/read/23493999/endothelial-morphometric-measures-to-predict-endothelial-graft-failure-after-penetrating-keratoplasty
#15
MULTICENTER STUDY
Beth Ann Benetz, Jonathan H Lass, Robin L Gal, Alan Sugar, Harry Menegay, Mariya Dontchev, Craig Kollman, Roy W Beck, Mark J Mannis, Edward J Holland, Mark Gorovoy, Sadeer B Hannush, John E Bokosky, James W Caudill
IMPORTANCE: Endothelial morphometric measures have potential value in predicting graft failure after penetrating keratoplasty. OBJECTIVE: To determine whether preoperative and/or postoperative central morphometric measures (endothelial cell density [ECD], coefficient of variation [CV], and percentage of hexagonality [HEX]) and their postoperative changes are predictive of graft failure caused by endothelial decompensation after penetrating keratoplasty to treat a moderate-risk condition, principally Fuchs dystrophy or pseudophakic corneal edema...
May 2013: JAMA Ophthalmology
https://www.readbyqxmd.com/read/23470589/pediatric-penetrating-keratoplasty
#16
Mary A O'Hara, Mark J Mannis
No abstract text is available yet for this article.
2013: International Ophthalmology Clinics
https://www.readbyqxmd.com/read/23343949/corneal-thickness-as-a-predictor-of-corneal-transplant-outcome
#17
David D Verdier, Alan Sugar, Keith Baratz, Roy Beck, Mariya Dontchev, Steven Dunn, Robin L Gal, Edward J Holland, Craig Kollman, Jonathan H Lass, Mark J Mannis, Jeffrey Penta
PURPOSE: To assess corneal thickness (CT) and correlation with graft outcome after penetrating keratoplasty in the Cornea Donor Study. METHODS: A total of 887 subjects with a corneal transplant for a moderate-risk condition (principally Fuchs dystrophy or pseudophakic corneal edema) had postoperative CT measurements throughout a 5-year follow-up time. Relationships between baseline (recipient, donor, and operative) factors and CT were explored. Proportional hazards models were used to assess the association between CT and graft failure...
June 2013: Cornea
https://www.readbyqxmd.com/read/23263222/intereye-asymmetry-detected-by-scheimpflug-imaging-in-subjects-with-normal-corneas-and-keratoconus
#18
Maria A Henriquez, Luis Izquierdo, Mark J Mannis
PURPOSE: To report the intereye asymmetry with regard to pachymetry and corneal elevation variables in subjects with normal corneas and in those with keratoconus. METHODS: This is a prospective study that included 151 patients who had Pentacam imaging in both eyes: 53 subjects with bilateral normal corneas and 98 with bilateral keratoconus. Central corneal thickness (CCT), pachymetry at the thinnest point (TP), posterior elevation at the thinnest point of the cornea (PETP), distance, volume, and differential pachymetry were measured...
June 2013: Cornea
https://www.readbyqxmd.com/read/22488114/effect-of-donor-and-recipient-factors-on-corneal-graft-rejection
#19
R Doyle Stulting, Alan Sugar, Roy Beck, Michael Belin, Mariya Dontchev, Robert S Feder, Robin L Gal, Edward J Holland, Craig Kollman, Mark J Mannis, Francis Price, Walter Stark, David D Verdier
PURPOSE: To assess the relationship between donor and recipient factors and corneal allograft rejection in eyes that underwent penetrating keratoplasty in the Cornea Donor Study. METHODS: Overall, 1090 subjects undergoing corneal transplantation for a moderate risk condition (principally Fuchs dystrophy or pseudophakic corneal edema) were followed for up to 5 years. Associations of baseline recipient and donor factors with the occurrence of a probable or definite rejection event were assessed in univariate and multivariate proportional hazards models...
October 2012: Cornea
https://www.readbyqxmd.com/read/22269677/practice-patterns-and-opinions-in-the-management-of-recurrent-or-chronic-herpes-zoster-ophthalmicus
#20
Aileen Sy, Stephen D McLeod, Elisabeth J Cohen, Todd P Margolis, Mark J Mannis, Thomas M Lietman, Nisha R Acharya
PURPOSE: The objective of this study was to determine current practices and opinions among cornea specialists for treating and preventing recurrences of herpes zoster ophthalmicus (HZO). METHODS: In November 2010, a survey of 15 questions was distributed to The Cornea Society listserv. Questions identified respondents' treatment practices for recurrent HZO and opinions regarding prolonged antiviral prophylaxis and zoster vaccine. RESULTS: Of 100 respondents, the majority were cornea specialists (83 of 98, 85%)...
July 2012: Cornea
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