keyword
MENU ▼
Read by QxMD icon Read
search

Mark A Terry

keyword
https://www.readbyqxmd.com/read/28797455/prognostic-factors-and-occult-nodal-disease-in-mucoepidermoid-carcinoma-of-the-oral-cavity-and-oropharynx-an-analysis-of-the-national-cancer-database
#1
Mark A Ellis, Evan M Graboyes, Terry A Day, David M Neskey
OBJECTIVES: Mucoepidermoid carcinoma (MEC) is an uncommon malignancy that most commonly occurs in the parotid gland followed by the minor salivary glands of the upper aerodigestive tract, most notably in the oral cavity (OC) and oropharynx (OP). Because of its rarity, few studies have been performed that are specific to MEC within the OC and OP. The objective of this study is to describe the tumor characteristics and prognostic features for MEC of the OC and OP. MATERIALS AND METHODS: The National Cancer Database (NCDB) was used for this study...
September 2017: Oral Oncology
https://www.readbyqxmd.com/read/28796902/spatio-temporal-variation-in-lifelong-telomere-dynamics-in-a-long-term-ecological-study
#2
Lewis G Spurgin, Kat Bebbington, Eleanor A Fairfield, Martijn Hammers, Jan Komdeur, Terry Burke, Hannah L Dugdale, David S Richardson
Understanding individual-level variation in response to the environment is fundamental to understanding life-history evolution and population dynamics. Telomeres, the protective caps at the ends of chromosomes, shorten in response to oxidative stress, and telomere shortening is correlated with reduced survival and lifespan. Investigating telomere dynamics may help us quantify individual variation in the costs experienced from social and ecological factors, and enhance our understanding of the dynamics of natural populations...
August 10, 2017: Journal of Animal Ecology
https://www.readbyqxmd.com/read/28765437/humanism-in-dental-education-a-comparison-of-theory-intention-and-stakeholder-perceptions-at-a-north-american-dental-school
#3
Lucinda Lyon, Lisa E Itaya, Terry Hoover, Mark T Booth, Nader Nadershahi
In today's dental education environment, a humanistic culture is an expectation for all U.S. dental schools, codified in 2013 by its inclusion in the Commission on Dental Accreditation's standards for accreditation. The University of the Pacific Arthur A. Dugoni School of Dentistry has made an active commitment to humanism since the mid-1970s. The aim of this study was to determine how well the school's students and faculty and staff members perceived the school was living up to its formal aspirational values and who was benefitting from the humanistic culture...
August 2017: Journal of Dental Education
https://www.readbyqxmd.com/read/28762674/identifying-genetic-sources-of-phenotypic-heterogeneity-in-orofacial-clefts-by-targeted-sequencing
#4
Jenna C Carlson, Margaret A Taub, Eleanor Feingold, Terri H Beaty, Jeffrey C Murray, Mary L Marazita, Elizabeth J Leslie
BACKGROUND: Orofacial clefts (OFCs), including nonsyndromic cleft lip with or without cleft palate (NSCL/P), are common birth defects. NSCL/P is highly heterogeneous with multiple phenotypic presentations. Two common subtypes of NSCL/P are cleft lip (CL) and cleft lip with cleft palate (CLP) which have different population prevalence. Similarly, NSCL/P can be divided into bilateral and unilateral clefts, with unilateral being the most common. Individuals with unilateral NSCL/P are more likely to be affected on the left side of the upper lip, but right side affection also occurs...
July 17, 2017: Birth defects research
https://www.readbyqxmd.com/read/28730707/establishment-and-characterization-of-a-novel-murine-model-of-pancreatic-cancer-cachexia
#5
Katherine A Michaelis, Xinxia Zhu, Kevin G Burfeind, Stephanie M Krasnow, Peter R Levasseur, Terry K Morgan, Daniel L Marks
BACKGROUND: Cachexia is a complex metabolic and behavioural syndrome lacking effective therapies. Pancreatic ductal adenocarcinoma (PDAC) is one of the most important conditions associated with cachexia, with >80% of PDAC patients suffering from the condition. To establish the cardinal features of a murine model of PDAC-associated cachexia, we characterized the effects of implanting a pancreatic tumour cell line from a syngeneic C57BL/6 KRAS(G12D) P53(R172H) Pdx-Cre(+/+) (KPC) mouse...
July 20, 2017: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/28720512/ahrq-series-on-complex-intervention-systematic-reviews-paper-5-advanced-analytic-methods
#6
Terri Pigott, Jane Noyes, Craig A Umscheid, Evan Myers, Sally C Morton, Rongwei Fu, Gillian D Sanders-Schmidler, Emily E Beth Devine, M Hassan Murad, Michael P Kelly, Chris Fonnesbeck, Mark Petticrew, Leila Kahwati, S Natasha Beretvas
BACKGROUND: Advanced analytic methods for synthesizing evidence about complex interventions continue to be developed. In this paper, we emphasize that the specific research question posed in the review should be used as a guide for choosing the appropriate analytic method. RATIONALE: We present advanced analytic approaches that address four common questions that guide reviews of complex interventions: 1) How effective is the intervention?; 2) For whom does the intervention work and in what contexts?; 3) What happens when the intervention is implemented?; and 4) What decisions are possible given the results of the synthesis? DISCUSSION: The analytic approaches presented in this paper are particularly useful when each primary study differs in components, mechanisms of action, context, implementation, timing, and many other domains...
June 27, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/28712987/the-tailored-study-a-randomized-controlled-trial-to-improve-surrogate-decision-making
#7
Daniel P Sulmasy, Mark T Hughes, Gayane Yenokyan, Joan Kub, Peter B Terry, Alan B Astrow, Julie A Johnson, Grace Ho, Marie T Nolan
CONTEXT: Patients with terminal illnesses often require surrogate decision makers. Prior research has demonstrated high surrogate stress, and that despite standards promoting substituted judgment, most patients do not want their surrogates to make pure substituted judgments for them. It is not known how best to help loved ones fulfill the surrogate role. OBJECTIVES: To test the effectiveness of an intervention to help surrogate decision makers. METHODS: 166 patients (41% with ALS and 59% with gastrointestinal cancers) and their surrogates at 2 university medical centers were randomized to an intensive nurse-directed discussion of the end of life Decision Control Preferences of the patient (TAILORED) or a discussion of nutrition (CONTROL); 163 completed baseline interviews and underwent the intervention...
July 13, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28691947/reply
#8
Angela Y Zhu, Devin Gattey, Anna Stagner, Mark A Terry, Albert S Jun
No abstract text is available yet for this article.
July 24, 2017: Cornea
https://www.readbyqxmd.com/read/28682298/wound-care-centers-critical-thinking-and-treatment-strategies-for-wounds
#9
Jean de Leon, Gregory A Bohn, Lawrence DiDomenico, Regina Fearmonti, H David Gottlieb, Katherine Lincoln, Jayesh B Shah, Mark Shaw, Horatio S Taveau Iv, Kerry Thibodeaux, John D Thomas, Terry A Treadwell
Many wound care centers (WCCs) provide a specialized level of care using various wound care therapies and are managed by quali ed healthcare professionals (QHPs) from di erent specialty backgrounds such as family medicine, podiatry, and plastic surgery. However, these QHPs are sometimes challenged by reimbursement issues, limited therapy and dressing options, reduced access to multidisciplinary team members, and cost-driven factors unique to WCCs. To help address these issues, a meeting was convened by an expert panel of WCC physicians to discuss best practices for treating complex patients in a WCC...
October 2016: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/28672128/exploring-pathways-linking-greenspace-to-health-theoretical-and-methodological-guidance
#10
REVIEW
Iana Markevych, Julia Schoierer, Terry Hartig, Alexandra Chudnovsky, Perry Hystad, Angel M Dzhambov, Sjerp de Vries, Margarita Triguero-Mas, Michael Brauer, Mark J Nieuwenhuijsen, Gerd Lupp, Elizabeth A Richardson, Thomas Astell-Burt, Donka Dimitrova, Xiaoqi Feng, Maya Sadeh, Marie Standl, Joachim Heinrich, Elaine Fuertes
BACKGROUND: In a rapidly urbanizing world, many people have little contact with natural environments, which may affect health and well-being. Existing reviews generally conclude that residential greenspace is beneficial to health. However, the processes generating these benefits and how they can be best promoted remain unclear. OBJECTIVES: During an Expert Workshop held in September 2016, the evidence linking greenspace and health was reviewed from a transdisciplinary standpoint, with a particular focus on potential underlying biopsychosocial pathways and how these can be explored and organized to support policy-relevant population health research...
June 30, 2017: Environmental Research
https://www.readbyqxmd.com/read/28669255/a-simple-and-inexpensive-way-to-document-simple-husbandry-in-animal-care-facilities-using-qr-code-scanning
#11
Tyler Green, Terry Smith, Richard Hodges, W Mark Fry
Record keeping within research animal care facilities is a key part of the guidelines set forth by national regulatory bodies and mandated by federal laws. Research facilities must maintain records of animal health issues, procedures and usage. Facilities are also required to maintain records regarding regular husbandry such as general animal checks, feeding and watering. The level of record keeping has the potential to generate excessive amounts of paper which must be retained in a fashion as to be accessible...
January 1, 2017: Laboratory Animals
https://www.readbyqxmd.com/read/28664976/diet-of-the-prehistoric-population-of-rapa-nui-easter-island-chile-shows-environmental-adaptation-and-resilience
#12
Catrine L Jarman, Thomas Larsen, Terry Hunt, Carl Lipo, Reidar Solsvik, Natalie Wallsgrove, Cassie Ka'apu-Lyons, Hilary G Close, Brian N Popp
OBJECTIVES: The Rapa Nui "ecocide" narrative questions whether the prehistoric population caused an avoidable ecological disaster through rapid deforestation and over-exploitation of natural resources. The objective of this study was to characterize prehistoric human diets to shed light on human adaptability and land use in an island environment with limited resources. MATERIALS AND METHODS: Materials for this study included human, faunal, and botanical remains from the archaeological sites Anakena and Ahu Tepeu on Rapa Nui, dating from c...
June 30, 2017: American Journal of Physical Anthropology
https://www.readbyqxmd.com/read/28664165/clearance-of-heparan-sulfate-and-attenuation-of-cns-pathology-by-intracerebroventricular-bmn-250-in-sanfilippo-type-b-mice
#13
Mika Aoyagi-Scharber, Danielle Crippen-Harmon, Roger Lawrence, Jon Vincelette, Gouri Yogalingam, Heather Prill, Bryan K Yip, Brian Baridon, Catherine Vitelli, Amanda Lee, Olivia Gorostiza, Evan G Adintori, Wesley C Minto, Jeremy L Van Vleet, Bridget Yates, Sara Rigney, Terri M Christianson, Pascale M N Tiger, Melanie J Lo, John Holtzinger, Paul A Fitzpatrick, Jonathan H LeBowitz, Sherry Bullens, Brett E Crawford, Stuart Bunting
Sanfilippo syndrome type B (mucopolysaccharidosis IIIB), caused by inherited deficiency of α-N-acetylglucosaminidase (NAGLU), required for lysosomal degradation of heparan sulfate (HS), is a pediatric neurodegenerative disorder with no approved treatment. Intracerebroventricular (ICV) delivery of a modified recombinant NAGLU, consisting of human NAGLU fused with insulin-like growth factor 2 (IGF2) for enhanced lysosomal targeting, was previously shown to result in marked enzyme uptake and clearance of HS storage in the Naglu(-/-) mouse brain...
September 15, 2017: Molecular Therapy. Methods & Clinical Development
https://www.readbyqxmd.com/read/28661408/a-note-from-the-editor-duchenne-muscular-dystrophy-genetics-the-fda-and-drug-pricing
#14
Mark Terry
DMD is a muscle-wasting disease. It is caused by mutations in the dystrophin gene which is found on the X chromosome. It has an X-linked recessive inheritance pattern and is passed on by the mother (carrier). It is a progressive disease that usually causes death in early adulthood-often in the 20s, although there have been improvements in treatment, so some patients make it into their 30s and occasionally 40s. In addition to the muscle wasting aspects, serious complications include heart or respiratory-related problems...
2017: Journal of the Association of Genetic Technologists
https://www.readbyqxmd.com/read/28655656/lessons-learned-from-read-across-case-studies-for-repeated-dose-toxicity
#15
Terry W Schultz, Mark T D Cronin
A series of case studies designed to further acceptance of read-across predictions, especially for chronic health-related endpoints, have been evaluated with regard to the knowledge and insight they provide. A common aim of these case studies was to examine sources of uncertainty associated with read-across. While uncertainty is related to the quality and quantity of the read across endpoint data, uncertainty also includes a variety of other factors, the foremost of which is uncertainty associated with the justification of similarity and quantity and quality of data for the source chemical(s)...
June 24, 2017: Regulatory Toxicology and Pharmacology: RTP
https://www.readbyqxmd.com/read/28640945/production-of-human-vitronectin-in-nicotiana-benthamiana-using-the-inpact-hyper-expression-platform
#16
Benjamin Dugdale, Maiko Kato, Pradeep Deo, Manuel Plan, Mark Harrison, Robyn Lloyd, Terry Walsh, Robert Harding, James Dale
Human vitronectin (hVN) is a glycoprotein that functions as a cell adhesion molecule and a regulator of coagulation in blood plasma and the extracellular matrix. In vitro, hVN is added to serum-free media in order to promote the adhesion of animal cells to tissue culture surfaces and the proliferation of undifferentiated stem cells. Here, we report the production of hVN in Nicotiana benthamiana using the inducible In Plant Activation (INPACT) hyper-expression platform. N. benthamiana plants were transformed with an INPACT expression cassette encoding hVN, and both the Tobacco yellow dwarf virus Rep/RepA activator and Tomato bushy stunt virus p19 gene under the transcriptional control of the ethanol-inducible AlcR:alcA gene switch...
June 22, 2017: Plant Biotechnology Journal
https://www.readbyqxmd.com/read/28619954/a-novel-immune-biomarker-ifi27-discriminates-between-influenza-and-bacteria-in-patients-with-suspected-respiratory-infection
#17
Benjamin M Tang, Maryam Shojaei, Grant P Parnell, Stephen Huang, Marek Nalos, Sally Teoh, Kate O'Connor, Stephen Schibeci, Amy L Phu, Anand Kumar, John Ho, Adrienne F A Meyers, Yoav Keynan, Terry Ball, Amarnath Pisipati, Aseem Kumar, Elizabeth Moore, Damon Eisen, Kevin Lai, Mark Gillett, Robert Geffers, Hao Luo, Fahad Gul, Jens Schreiber, Sandra Riedel, David Booth, Anthony McLean, Klaus Schughart
Host response biomarkers can accurately distinguish between influenza and bacterial infection. However, published biomarkers require the measurement of many genes, thereby making it difficult to implement them in clinical practice. This study aims to identify a single-gene biomarker with a high diagnostic accuracy equivalent to multi-gene biomarkers.In this study, we combined an integrated genomic analysis of 1071 individuals with in vitro experiments using well-established infection models.We identified a single-gene biomarker, IFI27, which had a high prediction accuracy (91%) equivalent to that obtained by multi-gene biomarkers...
June 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28592359/mercury-accumulation-in-lethrinus-nebulosus-from-the-marine-waters-of-the-qatar-eez
#18
Ebrahim M A S Al-Ansari, Mohamed A R Abdel-Moati, Oguz Yigiterhan, Ibrahim Al-Maslamani, Yousria Soliman, Gilbert T Rowe, Terry L Wade, Ismail M Al-Shaikh, Ahmed Helmi, Ligita Kuklyte, Mark Chatting, Mehsin A Al-Ansi Al-Yafei
Total mercury (THg) and methylmercury (MeHg) were recorded in the commercial demersal fish Lethrinus nebulosus, caught from six locations in Qatar EEZ (Exclusive Economic Zone). Concentrations of THg decreased in the order: liver˃muscle˃gonad. THg concentrations in fish tissue ranged from 0.016ppm in gonad to 0.855ppm (mgkg(-1)w/w) in liver tissues, while concentrations in muscle tissue ranged from 0.24 to 0.49ppm (mgkg(-1)w/w) among sampling sites. MeHg concentrations were used to validate food web transfer rate calculations...
June 4, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28574705/biochemical-profile-of-heritage-and-modern-apple-cultivars-and-application-of-machine-learning-methods-to-predict-usage-age-and-harvest-season
#19
Maria Anastasiadi, Fady Mohareb, Sally P Redfern, Mark Berry, Monique S J Simmonds, Leon A Terry
The present study represents the first major attempt to characterize the biochemical profile in different tissues of a large selection of apple cultivars sourced from the United Kingdom's National Fruit Collection comprising dessert, ornamental, cider, and culinary apples. Furthermore, advanced machine learning methods were applied with the objective to identify whether the phenolic and sugar composition of an apple cultivar could be used as a biomarker fingerprint to differentiate between heritage and mainstream commercial cultivars as well as govern the separation among primary usage groups and harvest season...
July 5, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28569355/comparative-physiology-of-vocal-musculature-in-two-odontocetes-the-bottlenose-dolphin-tursiops-truncatus-and-the-harbor-porpoise-phocoena-phocoena
#20
Nicole M Thometz, Jennifer L Dearolf, Robin C Dunkin, Dawn P Noren, Marla M Holt, Olivia C Sims, Brandon C Cathey, Terrie M Williams
The mechanism by which odontocetes produce sound is unique among mammals. To gain insight into the physiological properties that support sound production in toothed whales, we examined myoglobin content ([Mb]), non-bicarbonate buffering capacity (β), fiber-type profiles, and myosin heavy chain expression of vocal musculature in two odontocetes: the bottlenose dolphin (Tursiops truncatus; n = 4) and the harbor porpoise (Phocoena phocoena; n = 5). Both species use the same anatomical structures to produce sound, but differ markedly in their vocal repertoires...
May 31, 2017: Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology
keyword
keyword
68821
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"