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https://www.readbyqxmd.com/read/28937733/surface-engineering-of-graphene-composite-transparent-electrodes-for-high-performance-flexible-triboelectric-nanogenerators-and-self-powered-sensors
#1
Jun Yang, Peibo Liu, Xingzhan Wei, Wei Luo, Jin Yang, Hao Jiang, Dapeng Wei, Ruiying Shi, Haofei Shi
A high performance transparent and flexible triboelectric nanogenerator (TENG) based on graphene composite electrodes via surface engineering is proposed and demonstrated. Through modifying the CVD-grown graphene by conductive polymer poly(3,4-ethylenedioxy-thiophene):polystyrenesulfonate (PEDOT:PSS), the composite electrodes with excellent optoelectronic performances were fabricated, which exhibited a high transmittance up to 85% and sheet resistance of 85 Ω/□ decreasing from the initial value of 725 Ω/□...
September 22, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28933997/the-comfort-app-prototype-introducing-a-web-based-application-for-monitoring-comfort-in-palliative-care
#2
Sara Pinto, Filipe Almeida, Sílvia Caldeira, José Carlos Martins
AIM: To introduce a web-based application for monitoring comfort in patients receiving palliative care. METHODS: Multi-phase electronic application development process that concluded with a pilot design to assess the feasibility and acceptability of the developed app (n=7 patients). RESULTS: The app is compatible with Android, iOS and Windows. The results from phases I and II provided the knowledge about monitoring comfort. In phase III, five experts analysed the content of the app...
September 2, 2017: International Journal of Palliative Nursing
https://www.readbyqxmd.com/read/28928211/the-crispr-spacer-space-is-dominated-by-sequences-from-species-specific-mobilomes
#3
Sergey A Shmakov, Vassilii Sitnik, Kira S Makarova, Yuri I Wolf, Konstantin V Severinov, Eugene V Koonin
Clustered regularly interspaced short palindromic repeats and CRISPR-associated protein (CRISPR-Cas) systems store the memory of past encounters with foreign DNA in unique spacers that are inserted between direct repeats in CRISPR arrays. For only a small fraction of the spacers, homologous sequences, called protospacers, are detectable in viral, plasmid, and microbial genomes. The rest of the spacers remain the CRISPR "dark matter." We performed a comprehensive analysis of the spacers from all CRISPR-cas loci identified in bacterial and archaeal genomes, and we found that, depending on the CRISPR-Cas subtype and the prokaryotic phylum, protospacers were detectable for 1% to about 19% of the spacers (~7% global average)...
September 19, 2017: MBio
https://www.readbyqxmd.com/read/28925888/a-self-nanoemulsifying-drug-delivery-system-for-poorly-water-soluble-tolbutamide-development-optimization-and-pharmacodynamic-studies
#4
Deepti Pandita, Neelam Kumari, Viney Lather
The current investigation involves the development of a thermodynamically stable and dilutable self-nanoemulsifying drug delivery system (SNEDDS) for tolbutamide, a poorly water soluble hypoglycemic drug, in order to achieve higher water solubility and enhanced dissolution rate which in turn improves its oral bioavailability. Pseudo-ternary phase diagrams suggested the suitability of oleic acid (lipid), Tween 20 (surfactant) and PEG 400 (co-surfactant) for developing the SNEEDS formulations. The optimal SNEDDS formulation having mean globule diameter, viscosity, polydispersity value of 58...
September 15, 2017: Pharmaceutical Nanotechnology
https://www.readbyqxmd.com/read/28920423/self-organization-of-ions-at-the-interface-between-graphene-and-ionic-liquid-deme-tfsi
#5
Guangliang Hu, Gaind P Pandey, Qingfeng Liu, Radhika S Anaredy, Chunrui Ma, Ming Liu, Jun Li, Scott K Shaw, Judy Z Wu
Electrochemical effects manifest as nonlinear responses to an applied electric field in electrochemical devices, and are linked intimately to the molecular orientation of ions in the electric double layer (EDL). Herein, we probe the origin of the electrochemical effect using a double-gate graphene field effect transistor (GFET) of ionic liquid N,N-diethyl-N-(2-methoxyethyl)-N-methylammonium bis-(trifluoromethylsulfonyl)-imide (DEME-TFSI) top-gate, paired with a ferroelectric Pb0.92La0.08Zr0.52Ti0.48O3 (PLZT) back-gate of compatible gating efficiency...
September 18, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28917591/increased-left-prefrontal-brain-perfusion-after-mri-compatible-tdcs-attenuates-momentary-ruminative-self-referential-thoughts
#6
Chris Baeken, Jonathan Remue, Marie-Anne Vanderhasselt, Andre R Brunoni, Sara De Witte, Romain Duprat, Ernst H W Koster, Rudi De Raedt, Guo-Rong Wu
BACKGROUND: Transcranial direct current stimulation (tDCS) is a non-invasive electrical stimulation technique, assumed to influence cognition and emotional processing. OBJECTIVE: However, it is unclear how tDCS influences spontaneous cognitive processes such as momentary self-referential thoughts on the neuronal level. METHODS: Forty healthy female volunteers participated in a single session sham-controlled crossover tDCS study while being in the MRI scanner...
September 6, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28915488/plant-mating-systems-self-incompatibility-and-evolutionary-transitions-to-self-fertility-in-the-mustard-family
#7
REVIEW
June B Nasrallah
Flowering plants have evolved diverse mechanisms that promote outcrossing. The most widespread of these outbreeding devices are self-incompatibility systems, the highly selective prefertilization mating barriers that prevent self-fertilization by disrupting pollen-pistil interactions. Despite the advantages of outcrossing, loss of self-incompatibility has occurred repeatedly in many plant families. In the mustard family, the highly polymorphic receptors and ligands that mediate the recognition and inhibition of self-pollen in self-incompatibility have been characterized and the 3D structure of the receptor-ligand complex has been solved...
September 12, 2017: Current Opinion in Genetics & Development
https://www.readbyqxmd.com/read/28915003/the-evolution-of-dna-templated-synthesis-as-a-tool-for-materials-discovery
#8
Rachel K O'Reilly, Andrew J Turberfield, Thomas R Wilks
Precise control over reactivity and molecular structure is a fundamental goal of the chemical sciences. Billions of years of evolution by natural selection have resulted in chemical systems capable of information storage, self-replication, catalysis, capture and production of light, and even cognition. In all these cases, control over molecular structure is required to achieve a particular function: without structural control, function may be impaired, unpredictable, or impossible. The search for molecules with a desired function is often achieved by synthesizing a combinatorial library, which contains many or all possible combinations of a set of chemical building blocks (BBs), and then screening this library to identify "successful" structures...
September 15, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/28914554/when-cooperation-goes-wrong-brain-and-behavioral-correlates-of-ineffective-joint-strategies-in-dyads
#9
Michela Balconi, Laura Gatti, Maria Elide Vanutelli
Human life is connoted by sophisticated interactions that involve not only single individuals, but larger social groups composed by members interacting each other. Cooperation secures a benefit to all the people engaged as well as important behaviors like helping, sharing, and acting prosocially. But what happens when the joint actions are not effective? In the present study we asked 24 participants paired in 12 dyads to cooperate during an attentional task in a way to synchronize their responses and obtain better outcomes...
September 15, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/28914309/tetragonal-phase-of-cylinders-self-assembled-from-binary-blends-of-ab-diblock-and-a-b-n-star-copolymers
#10
Wenbo Jiang, Yicheng Qiang, Meijiao Liu, Weihua Li, Feng Qiu, An-Chang Shi
The phase behavior of binary blends composed of AB diblock and (A'B)n star copolymers is studied using the polymeric self-consistent field theory, focusing on the formation and stability of the stable tetragonal phase of cylinders. In general, cylindrical domains self-assembled from AB-type block copolymers are packed into a hexagonal array, although a tetragonal array of cylinders could be more favourable for lithography applications in microelectronics. The polymer blends are designed such that there is an attractive interaction between the A and A' blocks, which increases the compatibility between the two copolymers and thus suppresses the macroscopic phase separation of the blends...
September 15, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28911017/uncertain-pollination-environment-promotes-the-evolution-of-a-stable-mixed-reproductive-system-in-the-self-incompatible-hypochaeris-salzmanniana-asteraceae
#11
M Arista, R Berjano, J Viruel, M Á Ortiz, M Talavera, P L Ortiz
Background and aims: The transition from outcrossing to selfing is a repeated pattern in angiosperm diversification and according to general theory this transition should occur quickly and mixed reproductive systems should be infrequent. However, a large proportion of flowering plants have mixed reproductive systems, even showing inbreeding depression. Recently, several theoretical studies have shown that mixed mating systems can be stable, but empirical studies supporting these assumptions are still scarce...
September 1, 2017: Annals of Botany
https://www.readbyqxmd.com/read/28903598/healthcare-providers-attitude-and-knowledge-regarding-medication-use-in-breastfeeding-women-a-jordanian-national-questionnaire-study
#12
Nour A Al-Sawalha, Abeer Sawalha, Linda Tahaineh, Basima Almomani, Maha Al-Keilani
Medication use among women who have recently given birth is unavoidable in some situations. The aim of this study was to assess the attitude and knowledge of healthcare providers (HCPs) in Jordan about the safe use of medications during breastfeeding. The data were collected from HCPs in maternal and children care centres and hospitals from April 2015 to January 2016, using a self-administered questionnaire. A total of 904 HCPs (79.3%) were enrolled in the study. Half of the participants followed the World Health Organisation's and American Academy of Pediatrics' recommendations...
September 14, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28900511/a-nanosystem-of-amphiphilic-oligopeptide-drug-conjugate-actualizing-both-%C3%AE-v%C3%AE-3-targeting-and-reduction-triggered-release-for-maytansinoid
#13
Yanqin Liang, Suxin Li, Xiaoyou Wang, Bo He, Bing He, Wenbing Dai, Hua Zhang, Xueqing Wang, Yiguang Wang, Demin Zhou, Qiang Zhang
To design a prodrug-based self-assembling nanosystem with both ligand targeting and stimuli-responsive features, and elucidate the superiority of each targeting strategy and the synergistic effect between them, we synthesized four small molecule amphiphilic peptide-drug conjugates (APDCs) using maytansinoid (DM1) as a cytotoxic agent, cRGDfK as a homing peptide, and disulfide (SS) or thioether (SMCC) as linker. Owing to their amphiphilicity, the APDCs could self-assemble into nanoparticles (APDC@NPs) which were evaluated in vitro in three different cell lines and in vivo in tumor-bearing C57BL/6 mice...
2017: Theranostics
https://www.readbyqxmd.com/read/28892620/self-assembly-of-block-copolymer-chains-to-promote-the-dispersion-of-nanoparticles-in-polymer-nanocomposites
#14
Jun Liu, Zixuan Wang, Zhiyu Zhang, Jianxiang Shen, Yulong Chen, Zijian Zheng, Liqun Zhang, Alexey V Lyulin
In this paper we adopt molecular-dynamics simulations to study the amphiphilic AB block-copolymer (BCP) mediated nanoparticles (NPs) dispersion in polymer nanocomposites (PNCs), with the A-block being compatible with the NPs and the B-block being miscible with the polymer matrix. The effects of the number and components of BCP, as well as the interaction strength between A-block and NPs on the spatial organization of NPs are explored. We find the increase of the fraction of the A-block brings different dispersion effect to NPs than that of B-block...
September 11, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28892151/the-genetic-breakdown-of-sporophytic-self-incompatibility-in-tolpis-coronopifolia-asteraceae
#15
Boryana Koseva, Daniel J Crawford, Keely E Brown, Mark E Mort, John K Kelly
Angiosperm diversity has been shaped by mating system evolution, with the most common transition from outcrossing to self-fertilizing. To investigate the genetic basis of this transition, we performed crosses between two species endemic to the Canary Islands, the self-compatible (SC) species Tolpis coronopifolia and its self-incompatible (SI) relative Tolpis santosii. We scored self-compatibility as self-seed set of recombinant plants within two F2 populations. To map and genetically characterize the breakdown of SI, we built a draft genome sequence of T...
September 11, 2017: New Phytologist
https://www.readbyqxmd.com/read/28885981/from-surnames-to-linguistic-and-genetic-diversity-five-centuries-of-internal-migrations-in-spain
#16
Roberto Rodríguez-Díaz, María José Blanco-Villegas, Franz Manni
In a previous study concerning 33,753 single Spanish surnames (considered as tokens) occurring 51,419,788 times we have shown that the present-day geography of contemporary surname variability in Spain still corresponds to the political geography of the country at the end of the Middle Ages. Here we reprocess the same database, by clustering surnames with Self-Organizing Maps (SOMs) according to their geographic distribution, to identify the monophyletic surnames showing a geo-historical origin in one of the 47 provinces of continental Spain...
September 1, 2017: Journal of Anthropological Sciences, Rivista di Antropologia: JASS
https://www.readbyqxmd.com/read/28877755/uric-acid-an-important-screening-tool-to-detect-inborn-errors-of-metabolism-a-case-series
#17
Eresha Jasinge, Grace Angeline Malarnangai Kularatnam, Hewa Warawitage Dilanthi, Dinesha Maduri Vidanapathirana, Kandana Liyanage Subhashinie Priyadarshika Kapilani Menike Jayasena, Nambage Dona Priyani Dhammika Chandrasiri, Neluwa Liyanage Ruwan Indika, Pyara Dilani Ratnayake, Vindya Nandani Gunasekara, Lynette Dianne Fairbanks, Blanka Stiburkova
BACKGROUND: Uric acid is the metabolic end product of purine metabolism in humans. Altered serum and urine uric acid level (both above and below the reference ranges) is an indispensable marker in detecting rare inborn errors of metabolism. We describe different case scenarios of 4 Sri Lankan patients related to abnormal uric acid levels in blood and urine. CASE 1: A one-and-half-year-old boy was investigated for haematuria and a calculus in the bladder. Xanthine crystals were seen in microscopic examination of urine sediment...
September 6, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28874520/sipp-a-novel-mitochondrial-phosphate-carrier-mediates-in-self-incompatibility
#18
Liliana Elizabeth Garcia-Valencia, Carlos Everardo Bravo-Alberto, Hen-Ming Wu, Rogelio Rodriguez-Sotres, Alice Y Cheung, Felipe Cruz-Garcia
In Solanaceae, the S-specific interaction between the pistil S-RNase and the pollen S-Locus F-box (SLF) protein control self-incompatibility (SI). Although this interaction defines the specificity of the pollen rejection response, the identification of three pistil essential modifier genes unlinked to the S-locus (HT-B, 120K and NaStEP), unveils a higher degree of complexity in the pollen rejection pathway. We showed previously that NaStEP, a stigma protein with homology with Kunitz-type protease inhibitors, is essential to SI in Nicotiana...
September 5, 2017: Plant Physiology
https://www.readbyqxmd.com/read/28871935/topical-imiquimod-is-an-effective-and-safe-drug-for-molluscum-contagiosum-in-children
#19
George Badavanis, Efstathia Pasmatzi, Alexandra Monastirli, Sophia Georgiou, Dionysios Tsambaos
Dear Editor, Molluscum contagiosum (MC) is a very common skin infection caused by a molluscipox virus gene of the poxvirus family. It usually occurs in young children, sexually active adults, and immunocompromised individuals. The typical clinical picture of this infection is characterized by asymptomatic flesh-colored, single or multiple papules, measuring 2-6 mm in diameter with a central umbilication that occur on the skin and the mucous membranes. In adults, the skin lesions are predominantly located in the genital region, whereas in children they are found on the trunk, the extremities, and the face...
July 2017: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/28866571/conceptual-and-methodological-issues-in-evaluating-multidimensional-visualizations-for-decision-support
#20
Evanthia Dimara, Anastasia Bezerianos, Pierre Dragicevic
We explore how to rigorously evaluate multidimensional visualizations for their ability to support decision making. We first define multi-attribute choice tasks, a type of decision task commonly performed with such visualizations. We then identify which of the existing multidimensional visualizations are compatible with such tasks, and set out to evaluate three elementary visualizations: parallel coordinates, scatterplot matrices and tabular visualizations. Our method consists in first giving participants low-level analytic tasks, in order to ensure that they properly understood the visualizations and their interactions...
August 29, 2017: IEEE Transactions on Visualization and Computer Graphics
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