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Nada Shamie

Catarina E Hioe, Michael Tuen, Gaia Vasiliver-Shamis, Yelina Alvarez, Kathleen C Prins, Sagarika Banerjee, Arthur Nádas, Michael W Cho, Michael L Dustin, Scott C Kachlany
The cellular adhesion molecule LFA-1 and its ICAM-1 ligand play an important role in promoting HIV-1 infectivity and transmission. These molecules are present on the envelope of HIV-1 virions and are integral components of the HIV virological synapse. However, cellular activation is required to convert LFA-1 to the active conformation that has high affinity binding for ICAM-1. This study evaluates whether such activation can be induced by HIV itself. The data show that HIV-1 gp120 was sufficient to trigger LFA-1 activation in fully quiescent naïve CD4 T cells in a CD4-dependent manner, and these CD4 T cells became more susceptible to killing by LtxA, a bacterial leukotoxin that preferentially targets leukocytes expressing high levels of the active LFA-1...
2011: PloS One
Abu S Mustafa, Abdulsalam M El-Shamy, Nada M Madi, Hanady A Amoudy, Rajaa Al-Attiyah
OBJECTIVE: To evaluate cell-mediated immune (CMI) response in diabetic and non-diabetic tuberculosis (TB) patients and healthy subjects in response to complex, fractionated and single antigens of Mycobacteriumtuberculosis. MATERIAL AND METHODS: Peripheral blood mononuclear cells (PBMC) were obtained from patients suffering from pulmonary TB and type II diabetes (n = 7), pulmonary TB without diabetes (n = 10) and healthy subjects without TB and diabetes (n = 10)...
2008: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
M Nada, S Hanafi, H al-Omari, M Mokhtar, S el-Shamy, J Mühlbacher
No abstract text is available yet for this article.
August 1994: International Journal of Dermatology
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