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https://www.readbyqxmd.com/read/28316773/vitamin-d-treatment-during-pregnancy-prevents-autism-related-phenotypes-in-a-mouse-model-of-maternal-immune-activation
#1
Stephanie Vuillermot, Wei Luan, Urs Meyer, Darryl Eyles
BACKGROUND: Prenatal exposure to infection is a recognized environmental risk factor for neuropsychiatric disorders of developmental origins such as autism or schizophrenia. Experimental work in animals indicates that this link is mediated by maternal immune activation (MIA) involving interactions between cytokine-associated inflammatory events, oxidative stress, and other pathophysiological processes such as hypoferremia and zinc deficiency. Maternal administration of the viral mimic polyriboinosinic-polyribocytidylic acid (poly(I:C)) in mice produces several behavioral phenotypes in adult offspring of relevance to autism spectrum disorder (ASD) and other neurodevelopmental disorders...
2017: Molecular Autism
https://www.readbyqxmd.com/read/28287467/life-after-stroke-in-an-urban-minority-population-a-photovoice-project
#2
Revathi Balakrishnan, Benjamin Kaplan, Rennie Negron, Kezhen Fei, Judith Z Goldfinger, Carol R Horowitz
Stroke is a leading cause of disability in the United States and disproportionately affects minority populations. We sought to explore the quality of life in urban, minority stroke survivors through their own photos and narratives. Using the Photovoice method, seventeen stroke survivors were instructed to take pictures reflecting their experience living with and recovering from stroke. Key photographs were discussed in detail; participants brainstormed ways to improve their lives and presented their work in clinical and community sites...
March 11, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28282074/-epigenetics-2-0-the-multiple-faces-of-the-genome
#3
Marcelo Rubinstein
Epigenetics is the branch of genetics that studies the dynamic relationship between stable genotypes and varying phenotypes. To this end, epigenetics aims to discover the molecular mechanisms that explain how different nutrients and hormones, environmental changes, and emotional, social and cognitive experiences modify gene expression and behaviors, even permanently so. Psychiatry has learned that diseases with strong genetic predisposition, such as schizophrenia, show a concordance of around 50% between monozygotic twins, thus evidencing the importance of the genetic background and the presence of environmental variables that stimulate or block phenotypic development...
September 2016: Vertex: Revista Argentina de Psiquiatriá
https://www.readbyqxmd.com/read/28278165/indomethacin-counteracts-the-effects-of-chronic-social-defeat-stress-on-emotional-but-not-recognition-memory-in-mice
#4
Aránzazu Duque, Concepción Vinader-Caerols, Santiago Monleón
We have previously observed the impairing effects of chronic social defeat stress (CSDS) on emotional memory in mice. Given the relation between stress and inflammatory processes, we sought to study the effectiveness of the anti-inflammatory indomethacin in reversing the detrimental effects of CSDS on emotional memory in mice. The effects of CSDS and indomethacin on recognition memory were also evaluated. Male CD1 mice were randomly divided into four groups: non-stressed + saline (NS+SAL); non-stressed + indomethacin (NS+IND); stressed + saline (S+SAL); and stressed + indomethacin (S+IND)...
2017: PloS One
https://www.readbyqxmd.com/read/28277014/-you-are-labelled-by-your-children-s-disability-a-community-based-participatory-study-of-stigma-among-somali-parents-of-children-with-autism-living-in-the-united-kingdom
#5
Lucy Ellen Selman, Fiona Fox, Nura Aabe, Katrina Turner, Dheeraj Rai, Sabi Redwood
OBJECTIVES: Social stigma is commonly experienced by parents of children with autism. Our aim was to understand the nature of stigma experienced by Somali parents of children with autism in the United Kingdom (UK), and to consider how they coped with or resisted such stigma. DESIGN: We used a community-based participatory research approach, collaborating with a community organisation of Somali parents. In-depth interviews with simultaneous translation were conducted with 15 Somali parents of children with autism living in Bristol, UK, in 2015...
March 2, 2017: Ethnicity & Health
https://www.readbyqxmd.com/read/28275895/-emotiplay-a-serious-game-for-learning-about-emotions-in-children-with-autism-results-of-a-cross-cultural-evaluation
#6
S Fridenson-Hayo, S Berggren, A Lassalle, S Tal, D Pigat, N Meir-Goren, H O'Reilly, S Ben-Zur, S Bölte, S Baron-Cohen, O Golan
Children with autism spectrum conditions (ASC) experience difficulties recognizing others' emotions and mental states. It has been shown that serious games (SG) can produce simplified versions of the socio-emotional world. The current study performed a cross-cultural evaluation (in the UK, Israel and Sweden) of Emotiplay's SG, a system aimed to teach emotion recognition (ER) to children with ASC in an entertaining, and intrinsically motivating way. Participants were 6-9 year olds with high functioning ASC who used the SG for 8-12 weeks...
March 8, 2017: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/28272188/the-nurse-s-role-in-supporting-patients-and-family-in-sharing-personal-accounts-of-traumatic-events-a-personal-experience
#7
Jill Donaldson-Andersen
Life-changing events unfold quickly as trauma nurses provide care for patients during the most vulnerable time of their lives. Nurses also bear the weight of simultaneously caring and providing emotional support for the families of trauma victims. Trauma nurses have a profound responsibility to assist patients and families through this process, as well as having a unique opportunity to encourage families to share their personal stories and experiences. On occasion, some high-profile traumas make their way to the local news and inquiries from the media soon follow...
March 2017: Journal of Trauma Nursing: the Official Journal of the Society of Trauma Nurses
https://www.readbyqxmd.com/read/28268201/contrasting-approaches-to-the-response-contingent-learning-of-young-children-with-significant-delays-and-their-social-emotional-consequences
#8
Carl J Dunst, Melinda Raab, Deborah W Hamby
AIMS: The purpose of the analyses described in this paper was to evaluate the direct and indirect effects of two different approaches to child response-contingent learning on rates of child learning and both concomitant and collateral child social-emotional behaviour. METHOD: The participants were 71 children with significant developmental delays or multiple disabilities randomly assigned to either of the two contrasting approaches to interventions. RESULTS: Findings showed that an intervention which employed practices that built on existing child behaviour (asset-based practices) was more effective than an intervention focusing on teaching children missing skills (needs-based practices) for influencing changes in the rates of child learning as well as rates of child social-emotional behaviour mediated by differences in rates of child learning...
March 4, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/28266896/family-and-school-influences-on-youths-behavioral-and-academic-outcomes-cross-level-interactions-between-parental-monitoring-and-character-development-curriculum
#9
Namik Top, Jeffrey Liew, Wen Luo
The authors examined the joint (interactive) roles of the Second Step curriculum (a validated social-emotional learning and bullying prevention program; Committee for Children, Seattle, WA) and parenting practices on students' behavioral and academic outcomes in Grades 5-8. Participants were 763 parents and their children from 22 schools (8 control and 14 treatment). A 2-level random coefficient model was conducted to assess the effect of parental monitoring on school outcomes, as well as the interaction between character development curriculum and parental monitoring...
March 7, 2017: Journal of Genetic Psychology
https://www.readbyqxmd.com/read/28260243/aggressive-and-violent-behavior-and-emotional-self-efficacy-is-there-a-relationship-for-adolescents
#10
Robert F Valois, Keith J Zullig, Asa A Revels
BACKGROUND: In this cross-sectional study we explored relationships between aggressive and violent behaviors and emotional self-efficacy (ESE) in a statewide sample of public high school adolescents in South Carolina (N = 3836). METHODS: The US Centers for Disease Control and Prevention Youth Risk Behavior Survey items on aggressive and violent behavior items and an adolescent ESE scale were used. Logistic regression analyses and multivariate models constructed separately, revealed significant race by sex findings...
April 2017: Journal of School Health
https://www.readbyqxmd.com/read/28256072/perceived-social-support-in-adults-with-autism-spectrum-disorder-and-attention-deficit-hyperactivity-disorder
#11
Sonia Alvarez-Fernandez, Hallie R Brown, Yihong Zhao, Jessica A Raithel, Somer L Bishop, Sarah B Kern, Catherine Lord, Eva Petkova, Adriana Di Martino
Perceived social support (PSS) has been related to physical and mental well-being in typically developing individuals, but systematic characterizations of PSS in autism spectrum disorder (ASD) are limited. We compared self-report ratings of the multidimensional scale of PSS (MSPSS) among age- and IQ-matched groups of adults (18-58 years) with cognitively high-functioning ASD (N = 41), or attention-deficit/hyperactivity disorder (ADHD; N = 69), and neurotypical controls (NC; N = 69). Accompanying group comparisons, we used machine learning random forest (RF) analyses to explore predictors among a range of psychopathological and socio-emotional variables...
March 3, 2017: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/28254464/adra2b-deletion-variant-influences-time-dependent-effects-of-pre-learning-stress-on-long-term-memory
#12
Phillip R Zoladz, Alison M Dailey, Hannah E Nagle, Miranda K Fiely, Brianne E Mosley, Callie M Brown, Tessa J Duffy, Amanda R Scharf, McKenna B Earley, Boyd R Rorabaugh
Extensive work over the past few decades has shown that certain genetic variations interact with life events to confer increased susceptibility for the development of psychological disorders. The deletion variant of the ADRA2B gene, which has been associated with enhanced emotional memory and heightened amygdala responses to emotional stimuli, might confer increased susceptibility for the development of post-traumatic stress disorder (PTSD) or related phenotypes by increasing the likelihood of traumatic memory formation...
February 22, 2017: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/28253905/perceived-stress-and-quality-of-life-of-pharmacy-students-in-university-of-ghana
#13
Adomah Opoku-Acheampong, Irene A Kretchy, Franklin Acheampong, Barima A Afrane, Sharon Ashong, Bernice Tamakloe, Alexander K Nyarko
BACKGROUND: Stress among pharmacy students could greatly affect their learning activities and general well-being. It is therefore necessary to investigate how stress relates with the quality of life of students to maintain and/or improve their personal satisfaction and academic performance. A school-based longitudinal study was used to investigate the relationship between stress and quality of life of undergraduate pharmacy students. The 10-item perceived stress scale and the shorter version of the WHO quality of life scale were administered to the same participants at two time points i...
March 2, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28229247/achieving-population-level-change-through-a-system-contextual-approach-to-supporting-competent-parenting
#14
REVIEW
Matthew R Sanders, Kylie Burke, Ronald J Prinz, Alina Morawska
The quality of parenting children receive affects a diverse range of child and youth outcomes. Addressing the quality of parenting on a broad scale is a critical part of producing a more nurturing society. To achieve a meaningful population-level reduction in the prevalence rates of child maltreatment and social and emotional problems that are directly or indirectly influenced by parenting practices requires the adoption of a broad ecological perspective in supporting families to raise children. We make the case for adopting a multilevel, whole of population approach to enhance competent parenting and describe the essential tasks that must be accomplished for the approach to be successful and its effects measurable...
March 2017: Clinical Child and Family Psychology Review
https://www.readbyqxmd.com/read/28228573/grace-under-pressure-a-drama-based-approach-to-tackling-mistreatment-of-medical-students
#15
Karen M Scott, Špela Berlec, Louise Nash, Claire Hooker, Paul Dwyer, Paul Macneill, Jo River, Kimberley Ivory
A positive and respectful learning environment is fundamental to the development of professional identities in healthcare. Yet medical students report poor behaviour from healthcare professionals that contradict professionalism teaching. An interdisciplinary group designed and implemented a drama-based workshop series, based on applied theatre techniques, to help students develop positive professional qualities and interpersonal skills to deal with challenges in the healthcare setting. We piloted the workshops at the University of Sydney in 2015...
March 2017: Medical Humanities
https://www.readbyqxmd.com/read/28225843/-poverty-and-mental-disability-in-the-criminal-law-the-invisibles
#16
Ezequiel N Mercurio
In recent decades neuroscience research show the negative consequences of poverty in cognitive development. Environmental factors, such as material deprivation, exposure to stressful situations, violence, nutritional deprivation, environmental toxins may shape the developing brain. The changes of the structure and function of the brain since prenatal stages and their consequences can remain stable throughout the life cycle except early interventions are made. Research investigating have found significant link between child poverty and function and structural brain focusing on prefrontal cortex (i...
May 2016: Vertex: Revista Argentina de Psiquiatriá
https://www.readbyqxmd.com/read/28220025/management-of-cancer-in-the-older-age-person-an-approach-to-complex-medical-decisions
#17
Maria Vallet-Regí, Miguel Manzano, Leocadio Rodriguez-Mañas, Marta Checa López, Matti Aapro, Lodovico Balducci
The management of cancer in older aged people is becoming a common problem due to the aging of the population. There are many variables determining the complex situation that are interconnected. Some of them can be assessed, such as risk of mortality and risk of treatment complications, but many others are still unknown, such as the course of disease, the host-related factors that influence cancer aggressiveness, and the phenotype heralding risk of permanent treatment-related damage.This article presents a dynamic and personalized approach to older people with cancer based on our experience on aging, cancer, and their biological interactions...
February 20, 2017: Oncologist
https://www.readbyqxmd.com/read/28217305/redesigning-care-delivery-with-patient-support-personnel-learning-from-accountable-care-organizations
#18
Ksenia O Gorbenko, Taressa Fraze, Valerie A Lewis
INTRODUCTION: Accountable care organizations (ACOs) are a value-based payment model in the United States rooted in holding groups of healthcare providers financially accountable for the quality and total cost of care of their attributed population. To succeed in reaching their quality and efficiency goals, ACOs implement a variety of care delivery changes, including workforce redesign. Patient support personnel (PSP)-non-physician staff such as care coordinators, community health workers, and others-are critical to restructuring care delivery...
September 2016: Int J Care Coord
https://www.readbyqxmd.com/read/28213889/social-emotional-competence-an-essential-factor-for-promoting-positive-adjustment-and-reducing-risk-in-school-children
#19
Celene E Domitrovich, Joseph A Durlak, Katharine C Staley, Roger P Weissberg
Social-emotional competence is a critical factor to target with universal preventive interventions that are conducted in schools because the construct (a) associates with social, behavioral, and academic outcomes that are important for healthy development; (b) predicts important life outcomes in adulthood; (c) can be improved with feasible and cost-effective interventions; and (d) plays a critical role in the behavior change process. This article reviews this research and what is known about effective intervention approaches...
February 18, 2017: Child Development
https://www.readbyqxmd.com/read/28173849/rigour-and-rapport-a-qualitative-study-of-parents-and-professionals-experiences-of-joint-agency-infant-death-investigation
#20
Joanna Garstang, Frances Griffiths, Peter Sidebotham
BACKGROUND: In many countries there are now detailed Child Death Review (CDR) processes following unexpected child deaths. CDR can lead to a fuller understanding of the causes for each child's death but this potentially intrusive process may increase the distress of bereaved families. In England, a joint agency approach (JAA) is used where police, healthcare and social services investigate sudden child deaths together and a key part of this is the joint home visit (JHV) where specialist police and paediatricians visit the home with the parents to view the scene of death...
February 7, 2017: BMC Pediatrics
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