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Brain tumor AND respiratory

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https://www.readbyqxmd.com/read/28249186/attention-deficit-hyperactivity-disorder-symptoms-and-stress-related-biomarkers
#1
S W N Vogel, D Bijlenga, J Verduijn, T I Bron, A T F Beekman, J J S Kooij, B W J H Penninx
OBJECTIVE: The current study examined whether (a) Attention-Deficit/Hyperactivity Disorder (ADHD) symptoms were associated with dysregulation of stress-related mechanisms, and (b) whether ADHD symptoms interact with affective disorders in their association with dysregulated stress-related mechanisms. METHODS: Data were obtained from 2307 subjects participating in the Netherlands Study of Depression and Anxiety. Stress-related mechanisms were reflected by the following biomarkers: (1) hypothalamic-pituitary-adrenal axis indicators (salivary cortisol awakening curve, evening cortisol, cortisol suppression after a 0...
February 13, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28230738/clinical-implications-of-20-hydroxyeicosatetraenoic-acid-in-the-kidney-liver-lung-and-brain-an-emerging-therapeutic-target
#2
REVIEW
Osama H Elshenawy, Sherif M Shoieb, Anwar Mohamed, Ayman O S El-Kadi
Cytochrome P450-mediated metabolism of arachidonic acid (AA) is an important pathway for the formation of eicosanoids. The ω-hydroxylation of AA generates significant levels of 20-hydroxyeicosatetraenoic acid (20-HETE) in various tissues. In the current review, we discussed the role of 20-HETE in the kidney, liver, lung, and brain during physiological and pathophysiological states. Moreover, we discussed the role of 20-HETE in tumor formation, metabolic syndrome and diabetes. In the kidney, 20-HETE is involved in modulation of preglomerular vascular tone and tubular ion transport...
February 20, 2017: Pharmaceutics
https://www.readbyqxmd.com/read/28161317/a-characterization-of-cancer-patients-in-inpatient-rehabilitation-facilities-a-retrospective-cohort-study
#3
Jacqueline M Mix, Carl V Granger, Michael J LaMonte, Paulette Niewczyk, Margaret DiVita, Richard Goldstein, Jerome Yates, Jo L Freudenheim
OBJECTIVE: To identify the types of cancer patients admitted to inpatient medical rehabilitation and to describe their rehabilitation outcomes. DESIGN: Retrospective cohort study; SETTING: U.S. inpatient rehabilitation facilities (IRFs) PARTICIPANTS: Adult patients diagnosed with malignant cancer for a cancer related impairment admitted to an IRF between October 2010 and September 2012 were identified from the Uniform Data System for Medical Rehabilitation (UDSMR) database (n = 27,952)...
February 1, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28100321/-application-of-esmolol-in-severe-hand-foot-and-mouth-disease
#4
Lei Zhu, Bo-Xiang Qi, Dai-Hua Fang, Gong-Jian Qi, Kun Gao, Bao-Li Hu
OBJECTIVE: To study the clinical effect and mechanism of action of esmolol in the treatment of severe hand, foot, and mouth disease (HFMD). METHODS: A prospective randomized controlled trial was performed. A total of 102 children with severe HFMD were enrolled in the study and were randomly divided into conventional treatment and esmolol treatment groups (n=51 each). The children in the conventional treatment group were given conventional treatment according to the guidelines for the diagnosis and treatment of HFMD...
January 2017: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/27924209/postoperative-respiratory-difficulty-due-to-asymptomatic-anterior-cervical-osteophyte-after-brain-tumor-surgery-a-case-report
#5
Hye Won Shin, Joon Chul Jang, Hyong Hwan Lim, Min Kyung Park, Go Eun Bae, Seung Uk Choi, Ji Yong Park
Anterior cervical osteophytes are commonly found in elderly patients, but rarely produce symptoms. When symptoms occur, they can range from mild symptoms of dysphagia, dysphonia, and foreign body sensation to severe symptoms of airway obstruction due to compression of the pharynx or larynx. We report the case of a 59-year-old man who underwent brain tumor surgery, and developed post-operative respiratory difficulty due to progressive pharyngo-laryngeal edema, requiring urgent endotracheal intubation, secondary to the presence of a previously asymptomatic anterior cervical osteophyte...
December 2016: Korean Journal of Anesthesiology
https://www.readbyqxmd.com/read/27876089/rapid-onset-obesity-hypoventilation-hypothalamic-dysfunction-autonomic-dysregulation-and-neuroendocrine-tumor-syndrome-with-a-homogenous-enlargement-of-the-pituitary-gland-a-case-report
#6
Lama Aljabban, Lina Kassab, Nour Alhuda Bakoura, Mohammad Fayez Alsalka, Ismaeil Maksoud
BACKGROUND: Rapid-onset obesity with hypoventilation, hypothalamic dysfunction, and autonomic dysregulation syndrome is a rare pediatric disorder with a variable sequence of clinical presentations, undefined etiology, and high risk of mortality. Our patient presented an unusual course of the disease accompanied by a homogenous mild enlargement of her pituitary gland with an intact pituitary-endocrine axis which, to the best of our knowledge, represents a new finding in rapid-onset obesity with hypoventilation, hypothalamic dysfunction, and autonomic dysregulation syndrome...
November 22, 2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27819640/mature-teratoma-associated-with-bilateral-ovarian-carcinosarcoma-accidental-association-or-etiopathogenetic-determinism-case-report
#7
Rodica Birla, Elena-Roxana Catanescu, Andrei Caragui, Silviu Constantinoiu
Carcinosarcoma is a rare form of ovarian cancer with mixed origin, and its association with mature teratoma is extremely rare. We present the case of patient T. M. aged 67, admitted into our clinic on the 15/05/2016, F.O. 4877 for the increase of the abdominal volume. On admission, the patient was afebrile, conscious, cooperative, cardio-respiratory balanced, having the abdomen distended in volume, sharp dullness in the flanks, positive wave sign bioumoral within normal limits except: uric acid = 6.64 mg / dL, serum glucose = 113...
2016: Chirurgia
https://www.readbyqxmd.com/read/27765361/aralia-elata-var-mandshurica-rupr-maxim-j-wen-an-overview-of-pharmacological-studies
#8
REVIEW
Alexander N Shikov, Olga N Pozharitskaya, Valery G Makarov
PURPOSE: Aralia elata var. mandshurica (Rupr. & Maxim.) J.Wen syn. A. mandshurica Rupr. & Maxim is evaluated for its medicinal application. The aim of this study is to analyze pharmacological studies on A. elata var. mandshurica published until December 2015. METHODS: The information regarding the chemistry, safety, effectiveness, and pharmacological and clinical effects of A. elata was systematically collected from the scientific literature through library catalogs; online services such as E-library...
November 15, 2016: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/27764877/venous-thromboembolism-in-patients-undergoing-craniotomy-for-brain-tumors-a-u-s-nationwide-analysis
#9
REVIEW
David J Cote, Heloise M Dubois, Aditya V Karhade, Timothy R Smith
Background Patients who undergo craniotomy for brain tumor have an increased risk of developing venous thromboembolism (VTE). Using the National Surgical Quality Improvement Program (NSQIP) registry, patients undergoing craniotomy for brain tumor from 2006 and 2014 were analyzed to identify risk factors for postoperative VTE. Methods The study population, identified by Current Procedural Terminology codes, included all NSQIP-reported patients who underwent a craniotomy for brain tumor resection. Results There were 629 instances of VTE among 19,409 craniotomies for brain tumor (3...
November 2016: Seminars in Thrombosis and Hemostasis
https://www.readbyqxmd.com/read/27611984/assessment-of-systemic-cellular-inflammatory-response-after-spontaneous-intracerebral-hemorrhage
#10
J H Tapia-Pérez, D Karagianis, R Zilke, V Koufuglou, I Bondar, T Schneider
OBJECTIVE: After spontaneous intracerebral hemorrhage (ICH) a local and systemic inflammatory response is activated. Interleukin-6 (IL) is one of most relevant orchestrators of inflammatory responses in the brain and is released from multiple immune cells, including neutrophils. Herby we assessed the relevance of systemic inflammation in patients suffering ICH. METHODS: From October 2010 to October 2011 we included in our routine of laboratory investigations besides to C-reactive protein (CRP), the addition of IL-6 and an analysis of the subpopulation of circulating blood cells...
November 2016: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/27599481/the-lymphatic-vascular-system-of-the-mouse-head
#11
Melanie Lohrberg, Jörg Wilting
Histological studies of the lymphatic vascular system in adult mice are hampered because bones cannot be sectioned properly. Here, we decalcified the heads of 14-day-old mice, embedded them in paraffin and stained resultant serial sections with the lymphendothelial-specific antibodies Lyve-1 and Podoplanin. We show that the tissues with the highest lymphatic vascular density are the dermis and the oral mucous membranes. In contrast, the nasal mucous membrane is devoid of lymphatics, except for its most basal parts below the vomeronasal organ...
December 2016: Cell and Tissue Research
https://www.readbyqxmd.com/read/27591677/the-angiogenic-switch-leads-to-a-metabolic-shift-in-human-glioblastoma
#12
Krishna M Talasila, Gro V Røsland, Hanne R Hagland, Eskil Eskilsson, Irene H Flønes, Sabrina Fritah, Francisco Azuaje, Nadia Atai, Patrick N Harter, Michel Mittelbronn, Michael Andersen, Justin V Joseph, Jubayer Al Hossain, Laurent Vallar, Cornelis J F van Noorden, Simone P Niclou, Frits Thorsen, Karl Johan Tronstad, Charalampos Tzoulis, Rolf Bjerkvig, Hrvoje Miletic
BACKGROUND: Invasion and angiogenesis are major hallmarks of glioblastoma (GBM) growth. While invasive tumor cells grow adjacent to blood vessels in normal brain tissue, tumor cells within neovascularized regions exhibit hypoxic stress and promote angiogenesis. The distinct microenvironments likely differentially affect metabolic processes within the tumor cells. METHODS: In the present study, we analyzed gene expression and metabolic changes in a human GBM xenograft model that displayed invasive and angiogenic phenotypes...
September 3, 2016: Neuro-oncology
https://www.readbyqxmd.com/read/27588138/medullary-metastasis-of-a-malignant-peripheral-nerve-sheath-tumor-a-case-report
#13
Tomohito Hagi, Tomoki Nakamura, Ayumu Yokoji, Akihiko Matsumine, Akihiro Sudo
The present study reports a case of medullary metastasis without lung metastasis that occurred as a result of a malignant peripheral nerve sheath tumor (MPNST). An 81-year-old woman presented with a MPNST in the left brachial plexus, arising from the cervical nerve root. The patient underwent carbon ion radiotherapy; however, tumor recurrence was identified in the left shoulder. Subsequently, the patient underwent wide excision. Three weeks subsequent to surgery, imbalance and dysarthria developed suddenly...
September 2016: Oncology Letters
https://www.readbyqxmd.com/read/27565730/deleted-in-malignant-brain-tumors-1-protein-is-a-potential-biomarker-of-acute-respiratory-distress-syndrome-induced-by-pneumonia
#14
Shan Ren, Xia Chen, Li Jiang, Bo Zhu, Qi Jiang, Xiuming Xi
Acute respiratory distress syndrome (ARDS) is associated with high mortality and morbidity. Early diagnosis and risk stratification in patients with ARDS should improve prognosis. Unfortunately, no clinical biomarkers are available for use in early diagnosis. Quantitative proteomics is a powerful tool for biomarker discovery in cancer, autoimmune diseases, and ARDS. Here, we employed isobaric tags for relative and absolute quantitation (iTRAQ) technology to identify potential biomarkers for early ARDS diagnosis and predict the risk for increased disease severity induced by pneumonia...
September 23, 2016: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/27557073/-autoimmune-encephalitis
#15
Albrecht Günther, Julia Schubert, Dirk Brämer, Otto Wilhelm Witte
Autoimmune encephalitis, an inflammatory disease of the brain, is usually attributed to antibody-mediated damage and dysfunction of neuronal structures. A distinction is made between onconeuronal antibodies (directed against intracellular neuronal antigens with resulting paraneoplastic neurological syndromes) and antibodies directed against neuronal cell surface proteins (with resulting synaptic encephalopathies). Anti-NMDA-Receptor-Encephalitis, the most common form of autoimmune encephalopathy, is characterized by a phased course of disease...
August 2016: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/27542528/critical-re-evaluation-of-neuroglobin-expression-reveals-conserved-patterns-among-mammals
#16
Andrej Fabrizius, Daniel Andre, Tilmann Laufs, Anne Bicker, Stefan Reuss, Elena Porto, Thorsten Burmester, Thomas Hankeln
Neuroglobin (Ngb) is a respiratory protein that is almost exclusively expressed in the vertebrate nervous system. Despite many years of research, the exact function and even the expression sites of Ngb are still a matter of debate. However, to investigate hypotheses surrounding the potential roles of Ngb, a detailed knowledge of its major and minor expression sites is indispensable. We have therefore evaluated Ngb expression by extensive bioinformatic analysis using publicly available transcriptome data (RNA-Seq)...
August 16, 2016: Neuroscience
https://www.readbyqxmd.com/read/27453748/predictors-of-early-infection-in-cerebral-ischemic-stroke
#17
Wmr Ashour, A D Al-Anwar, A E Kamel, M A Aidaros
BACKGROUND: Infection is the most common complication of stroke. AIM: To determine the risk factors and predictors of post-stroke infection (PSI), which developed within 7 days from the onset of acute ischemic stroke. SUBJECTS: The study included 60 ischemic stroke patients admitted in the Neurology Department of Zagazig University, Egypt, who were subdivided into: [Non Stroke Associated Infection group (nSAI); 30 patients having stroke without any criteria of infection within 7 days from the onset and Stroke Associated Infection group (SAI); 30 patients having stroke with respiratory tract infection (RTI) or urinary tract infection within 7 days], in addition to 30 healthy sex and age-matching subjects as control...
April 2016: Journal of Medicine and Life
https://www.readbyqxmd.com/read/27399404/125%C3%A2-transorbital-ultrasound-measurement-as-a-noninvasive-marker-of-intracranial-pressure
#18
Llewellyn Padayachy, Graham A G Fieggen
INTRODUCTION: Reliable assessment of intracranial pressure (ICP) remains crucial in managing neurosurgical conditions in children. The present study examined the relationship between transorbital ultrasound measurement of the optic nerve sheath diameter (ONSD) and invasively measured ICP in children. METHODS: This was a prospective, observational study comparing ONSD measurement with invasive ICP measurement. All patients were under general anesthesia and physiological variables, including systolic and diastolic blood pressure, mean arterial pressure, pulse rate, temperature, respiratory rate, and end-tidal carbon dioxide level, were recorded at the time of ONSD measurement...
August 2016: Neurosurgery
https://www.readbyqxmd.com/read/27316915/french-intensive-care-society-international-congress-r%C3%A3-animation-2016
#19
(no author information available yet)
No abstract text is available yet for this article.
June 2016: Annals of Intensive Care
https://www.readbyqxmd.com/read/27259293/canine-influenza-virus-coinfection-with-staphylococcus-pseudintermedius-enhances-bacterial-colonization-virus-load-and-clinical-presentation-in-mice
#20
Dildar Hussain Kalhoro, Shanshan Gao, Xing Xie, Shan Liang, Su Luo, Yanbing Zhao, Yongjie Liu
BACKGROUND: Canine influenza virus (CIV) and Staphylococcus pseudintermedius (Sp) are pathogens that cause respiratory disease in dogs. Considering bacterial infections following influenza are a leading cause of illness and death, it is of particular meaning to investigate the interaction between these two pathogens. In this study, BALB/c mice were used as a mouse model to assess whether inoculation with CIV H3N2 followed by S. pseudintermedius 72 h later resulted in exacerbation of disease...
June 4, 2016: BMC Veterinary Research
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