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https://www.readbyqxmd.com/read/29138680/enhancement-of-antioxidant-mechanisms-and-reduction-of-oxidative-stress-in-chickens-after-the-administration-of-drinking-water-enriched-with-polyphenolic-powder-from-olive-mill-waste-waters
#1
Aliki Papadopoulou, Konstantinos Petrotos, Dimitrios Stagos, Konstantinos Gerasopoulos, Antonios Maimaris, Haralampos Makris, Ioannis Kafantaris, Sotiria Makri, Efthalia Kerasioti, Maria Halabalaki, Vincent Brieudes, Georgia Ntasi, Stylianos Kokkas, Pavlos Tzimas, Panagiotis Goulas, Alexander M Zakharenko, Kirill S Golokhvast, Aristidis Tsatsakis, Demetrios Kouretas
The aim of the study was to examine the effects of a polyphenolic powder from olive mill wastewater (OMWW) administered through drinking water, on chickens' redox status. Thus, 75 chickens were divided into three groups. Group A was given just drinking water, while groups B and C were given drinking water containing 20 and 50 μg/ml of polyphenols, respectively, for 45 days. The antioxidant effects of the polyphenolic powder were assessed by measuring oxidative stress biomarkers in blood after 25 and 45 days of treatment...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/29134727/a-srna-in-a-reduced-mutualistic-symbiont-genome-regulates-its-own-gene-expression
#2
Margaret W Thairu, Siyuan Cheng, Allison K Hansen
Similar to other nutritional endosymbionts that are obligate for host survival, the mutualistic aphid endosymbiont, Buchnera, has a highly reduced genome with few regulatory elements. Until recently, it was thought that aphid hosts were primarily responsible for regulating their symbiotic relationship. However, we recently revealed that Buchnera displays differential protein regulation, but not mRNA expression. We also identified a number of conserved small RNAs (sRNAs) that are expressed among Buchnera taxa...
November 13, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/29048822/-determination-of-pyrethroid-pesticides-in-tea-by-series-two-solid-phase-extraction-columns-cleanup-and-gas-chromatography-tandem-mass-spectrometry
#3
Li Liu, Qi Zhang, Haiyan Wang, Feng Feng, Hairong Cao, Zhen Yang, Zhijun Ke, Xiyao Chen
A rapid determination method of three pyrethroid pesticides (cyfluthrin, cypermethrin and fenvalerate) in tea was developed by series two-solid phase extraction-column cleanup and external standard method coupled with gas chromatography-tandem mass spectrometry (GC-MS/MS) in 30 min. The pesticide residues in tea were extracted with acetonitrile, and cleaned up by Carb/NH2 and SLH solid-phase extraction columns. After filtration, the target compounds were analyzed by GC-MS and quantified by the external standard method...
August 8, 2017: Se Pu, Chinese Journal of Chromatography
https://www.readbyqxmd.com/read/29019666/airborne-methane-emission-measurements-for-selected-oil-and-gas-facilities-across-california
#4
Shobhit Mehrotra, Ian Faloona, Maxime Suard, Stephen Conley, Marc L Fischer
We report 65 individual measurements of methane emissions from 24 oil and gas facilities across California. Methane emission rates were estimated using in situ methane and wind velocity measurements from a small aircraft by a novel Gauss' Theorem flux integral approach. The estimates are compared with annual mean emissions reported to the U.S. Environmental Protection Agency (USEPA) and the California Air Resources Board (CARB) through their respective greenhouse gas reporting programs. The average emissions from 36 measurements of 10 gas storage facilities were within a factor of 2 of emissions reported to USEPA or CARB, though large variance was observed and the reporting database did not contain all of the facilities...
November 7, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28978421/dietary-carbohydrates-impair-healthspan-and-promote-mortality
#5
Meenakshi Ravichandran, Gerald Grandl, Michael Ristow
The prospective cohort study, named PURE, found that in >135,000 participants from 18 countries, nutritive carbohydrates increase human mortality, whereas dietary fat reduces it, requesting a fundamental change of current nutritional guidelines. Experimental evidence from animal models provides synergizing mechanistic concepts as well as pharmacological options to mimic low-carb or ketogenic diets.
October 3, 2017: Cell Metabolism
https://www.readbyqxmd.com/read/28957355/an-augmented-reality-game-to-support-therapeutic-education-for-children-with-diabetes
#6
Andrés-Marcelo Calle-Bustos, M-Carmen Juan, Inmaculada García-García, Francisco Abad
Therapeutic education in diabetes helps patients take responsibility for self-control of their disease, and providing technological support systems facilitates this education. In this paper, we present an augmented reality game to support therapeutic education for patients with diabetes. Our game helps children (aged 5-14 years) to learn carbohydrate (carb) content of different foods. The game shows virtual foods on a real dish. The number of carb choices corresponding to the visualized food is also shown (1 carb choice = 10 grams of carbs)...
2017: PloS One
https://www.readbyqxmd.com/read/28932477/crystal-structure-of-n-2-cyclo-hexyl-sulfan-yl-eth-yl-quinolinic-acid-imide
#7
Hyunjin Park, Myong Yong Choi, Cheol Joo Moon, Tae Ho Kim
The title compound, C15H18N2O2S {systematic name: 6-[2-(cyclo-hexyl-sulfan-yl)eth-yl]-5H-pyrrolo-[3,4-b]pyridine-5,7(6H)-dione}, was obtained from the reaction of pyridine-2,3-di-carb-oxy-lic anhydride (synonym: quinolinic anhydride) with 2-(cyclo-hexyl-sulfan-yl)ethyl-amine. The dihedral angle between the mean plane of the cyclo-hexyl ring and the quinolinic acid imide ring is 25.43 (11)°. In the crystal, each mol-ecule forms two C-H⋯O hydrogen bonds and one weak C-O⋯π [O⋯ring centroid = 3.255 (2) Å] inter-action with neighbouring mol-ecules to generate a ladder structure along the b-axis direction...
September 1, 2017: Acta Crystallographica. Section E, Crystallographic Communications
https://www.readbyqxmd.com/read/28932476/crystal-structures-of-hibiscus-acid-and-hibiscus-acid-dimethyl-ester-isolated-from-hibiscus-sabdariffa-malvaceae
#8
Ahmed M Zheoat, Alexander I Gray, John O Igoli, Alan R Kennedy, Valerie A Ferro
The biologically active title compounds have been isolated from Hibiscus sabdariffa plants, hibiscus acid as a dimethyl sulfoxide monosolvate [systematic name: (2S,3R)-3-hy-droxy-5-oxo-2,3,4,5-tetra-hydro-furan-2,3-di-carb-oxy-lic acid dimethyl sulfoxide monosolvate], C6H6O7·C2H6OS, (I), and hibiscus acid dimethyl ester [systematic name: dimethyl (2S,3R)-3-hy-droxy-5-oxo-2,3,4,5-tetra-hydro-furan-2,3-di-carboxyl-ate], C8H10O7, (II). Compound (I) forms a layered structure with alternating layers of lactone and solvent mol-ecules, that include a two-dimensional hydrogen-bonding construct...
September 1, 2017: Acta Crystallographica. Section E, Crystallographic Communications
https://www.readbyqxmd.com/read/28932450/a-new-solvate-of-epalerstat-a-drug-for-diabetic-neuropathy
#9
Okky Dwichandra Putra, Daiki Umeda, Kaori Fukuzawa, Mihoko Gunji, Etsuo Yonemochi
Epalerstat {systematic name: (5Z)-5-[(2E)-2-methyl-3-phenyl-prop-2-en-1-yl-idene]-4-oxo-2-sulfanyl-idene-1,3-thia-zolidine-3-acetic acid} crystallized as an acetone monosolvate, C15H13NO3S2·C3H6O. In the epalerstat mol-ecule, the methyl-propyl-enediene moiety is inclined to the phenyl ring and the five-membered rhodamine ring by 21.4 (4) and 4.7 (4)°, respectively. In addition, the acetic acid moiety is found to be almost normal to the rhodamine ring, making a dihedral angle of 85.1 (2)°. In the crystal, a pair of O-H⋯O hydrogen bonds between the carb-oxy-lic acid groups of epalerstat mol-ecules form inversion dimers with an R2(2)(8) loop...
July 1, 2017: Acta Crystallographica. Section E, Crystallographic Communications
https://www.readbyqxmd.com/read/28932437/coordination-compounds-containing-bis-di-thiol-ene-chelated-molybdenum-iv-and-oxalate-comparison-of-terminal-with-bridging-oxalate
#10
Agata Gapinska, Alan J Lough, Ulrich Fekl
Two coordination compounds containing tetra-n-butyl-ammonium cations and bis-tfd-chelated molybdenum(IV) [tfd(2-) = S2C2(CF3)2(2-)] and oxalate (ox(2-), C2O4(2-)) in complex anions are reported, namely bis-(tetra-n-butyl-ammonium) bis-(1,1,1,4,4,4-hexa-fluoro-but-2-ene-2,3-di-thiol-ato)oxalatomolybdate(IV)-chloro-form-oxalic acid (1/1/1), (C16H36N)2[Mo(C4F6S2)2(C2O4)]·CHCl3·C2H2O4 or (N (n) Bu4)2[Mo(tfd)2(ox)]·CHCl3·C2H2O4, and bis-(tetra-n-butyl-ammonium) μ-oxalato-bis-[bis-(1,1,1,4,4,4-hexa-fluoro-but-2-ene-2,3-di-thiol-ato)molybdate(IV)], (C16H36N)2[Mo2(C4F6S2)4(C2O4)] or (N (n) Bu4)2[(tfd)2Mo(μ-ox)Mo(tfd)2]...
July 1, 2017: Acta Crystallographica. Section E, Crystallographic Communications
https://www.readbyqxmd.com/read/28932435/crystal-structures-of-4-meth-oxy-benzoic-acid-1-3-bis-pyridin-4-yl-propane-2-1-and-biphenyl-4-4-di-carb-oxy-lic-acid-4-meth-oxy-pyridine-1-2
#11
Kazuma Gotoh, Hiroyuki Ishida
The crystal structures of two hydrogen-bonded compounds, namely 4-meth-oxy-benzoic acid-1,3-bis-(pyridin-4-yl)propane (2/1), C13H14.59N2·C8H7.67O3·C8H7.74O3, (I), and biphenyl-4,4'-di-carb-oxy-lic acid-4-meth-oxy-pyridine (1/2), C14H9.43O4·C6H7.32NO·C6H7.25NO, (II), have been determined at 93 K. In (I), the asymmetric unit consists of two crystallographically independent 4-meth-oxy-benzoic acid mol-ecules and one 1,3-bis-(pyridin-4-yl)propane mol-ecule. The asymmetric unit of (II) comprises one biphenyl-4,4'-di-carb-oxy-lic acid mol-ecule and two independent 4-meth-oxy-pyridine mol-ecules...
July 1, 2017: Acta Crystallographica. Section E, Crystallographic Communications
https://www.readbyqxmd.com/read/28926062/selectivity-of-solid-phase-extraction-for-dissolved-organic-matter-in-the-hypersaline%C3%A2-da-qaidam-lake-china
#12
Keli Yang, Yaoling Zhang, Yaping Dong, Wu Li
Dissolved organic matter (DOM) was isolated from the hypersaline Da Qaidam Lake using solid-phase extraction (SPE) methods with five different adsorbents: ENVI-Carb (non-porous graphitized carbon), HLB, PPL, and XAD-8 (polymer based), and ENVI-18 (silica based). Structure-selective assessments of SPE-DOM isolated using the different adsorbents were conducted using a combination of complementary analysis techniques, including dissolved organic carbon (DOC) and dissolved organic nitrogen (DON) analysis, as well as elemental analysis, Fourier transformed infrared spectroscopy (FTIR), (1)H nuclear magnetic resonance ((1)H NMR) and pyrolysis-gas chromatography-mass spectrometry (Py-GC/MS)...
November 15, 2017: Environmental Science. Processes & Impacts
https://www.readbyqxmd.com/read/28925409/metabolic-and-genomic-adaptations-to-winter-fattening-in-a-primate-species-the-grey-mouse-lemur-microcebus-murinus
#13
J Terrien, M Gaudubois, D Champeval, V Zaninotto, L Roger, J F Riou, F Aujard
AIM: To understand the mechanisms underlying the development of metabolic changes leading to obesity remains a major world health issue. Among such mechanisms, seasonality is quite underestimated although it corresponds to the manifestation of extreme metabolic flexibility in response to a changing environment. Nevertheless, the changes induced by such flexibility are far to be understood, especially at the level of insulin signaling, genomic stability or inflammation. METHODS: Here, we investigated the metabolic regulations displayed by a seasonal primate species, the grey mouse lemur (Microcebus murinus) that exhibits pronounced changes in body mass during the 6-month winter season: a fattening period followed by a spontaneous fat loss, without ever reaching pathological stages...
August 14, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28924296/applied-carbohydrate-counting
#14
Lovely Gupta, Deepak Khandelwal, Sanjay Kalra
Carbohydrate counting or "carb counting" is a meal planning technique for persons with diabetes for managing blood glucose levels by tracking the grams of carbohydrate consumed at meals. With better patient education and awareness, carb counting has become an important step in diabetes management. People with all types of diabetes can be benefited with this approach via improved glycaemic control and quality of life. In the first part of this review basic principles of carbohydrate counting, its application in clinical practice and exchange lists pertaining primarily to South Asian populations have been discussed...
September 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28877453/disentangling-high-fat-low-carb-and-healthy-aging
#15
Holly M Brown-Borg
Dietary interventions are simple, non-invasive tools that can be utilized to improve health and lifespan. In this issue, Roberts et al. (2017) and Newman et al. (2017) reveal the physiological benefits of feeding mice ketogenic diets and suggest different underlying mechanisms that may promote healthy aging.
September 5, 2017: Cell Metabolism
https://www.readbyqxmd.com/read/28875027/viscous-hydrophilic-injection-matrices-for-serial-crystallography
#16
Gabriela Kovácsová, Marie Luise Grünbein, Marco Kloos, Thomas R M Barends, Ramona Schlesinger, Joachim Heberle, Wolfgang Kabsch, Robert L Shoeman, R Bruce Doak, Ilme Schlichting
Serial (femtosecond) crystallography at synchrotron and X-ray free-electron laser (XFEL) sources distributes the absorbed radiation dose over all crystals used for data collection and therefore allows measurement of radiation damage prone systems, including the use of microcrystals for room-temperature measurements. Serial crystallography relies on fast and efficient exchange of crystals upon X-ray exposure, which can be achieved using a variety of methods, including various injection techniques. The latter vary significantly in their flow rates - gas dynamic virtual nozzle based injectors provide very thin fast-flowing jets, whereas high-viscosity extrusion injectors produce much thicker streams with flow rates two to three orders of magnitude lower...
July 1, 2017: IUCrJ
https://www.readbyqxmd.com/read/28839326/carbohydrate-counting-1-south-asian-framework
#17
Lovely Gupta, Deepak Khandelwal, Sanjay Kalra
Carbohydrate counting or "carb counting" is a meal planning technique for persons with diabetes for managing blood glucose levels by tracking the grams of carbohydrate consumed at meals. It has shown to improve glycaemic control and glycaemic variability and decreases risk of hypoglycaemia in persons with diabetes especially on insulins. It needs basic education of the patient regarding meal plan, assessment of carbohydrate content of various foods and also exchange lists. It also gives flexibility of food choice, helps to identify patterns in blood glucose levels and adjustment of pre meals short acting insulins as related to food intake...
August 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28817770/photoinduced-copper-catalyzed-alkylation-of-amines-a-mechanistic-study-of-the-cross-coupling-of-carbazole-with-alkyl-bromides
#18
Jun Myun Ahn, Tanvi S Ratani, Kareem I Hannoun, Gregory C Fu, Jonas C Peters
We have recently reported that a variety of couplings of nitrogen, sulfur, oxygen, and carbon nucleophiles with organic halides can be achieved under mild conditions (-40 to 30 °C) through the use of light and a copper catalyst. Insight into the various mechanisms by which these reactions proceed may enhance our understanding of chemical reactivity and facilitate the development of new methods. In this report, we apply an array of tools (EPR, NMR, transient absorption, and UV-vis spectroscopy; ESI-MS; X-ray crystallography; DFT calculations; reactivity, stereochemical, and product studies) to investigate the photoinduced, copper-catalyzed coupling of carbazole with alkyl bromides...
September 13, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28761649/discovering-successful-strategies-for-diabetic-self-management-a-qualitative-comparative-study
#19
Susan C Weller, Roberta Baer, Anita Nash, Noe Perez
OBJECTIVE: This project explored lifestyles of patients in good and poor control to identify naturally occurring practices and strategies that result in successful diabetes management. RESEARCH DESIGN AND METHODS: Semistructured interviews with adult patients with type 2 diabetes explored diet, food preparation, physical activity, medication use and glucose monitoring. Patients (n=56) were classified into good (A1C <7.0%), fair (7.0%<A1C<8.0%) or poor (A1C >8...
2017: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/28754100/identifying-genomic-targets-for-protein-over-expression-by-omics-analysis-of-quiescent-escherichia-coli-cultures
#20
Shubhashree Mahalik, Ashish Kumar Sharma, Priyanka Jain, Krishna Jyoti Mukherjee
BACKGROUND: A cellular stress response is triggered upon induction of recombinant protein expression which feedback inhibits both growth as well as protein synthesis. In order to separate these two effects, it was decided to study "quiescent cultures" which continue to be metabolically active and express recombinant proteins even after growth cessation. The idea was to identify and up-regulate genes which are responsible for protein synthesis in the absence of growth. This would ensure that, even if growth were adversely affected post induction, there would be no attendant reduction in the protein expression capability of the cells...
July 28, 2017: Microbial Cell Factories
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