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https://www.readbyqxmd.com/read/28535303/a-novel-goldnano-carb-test-for-rapid-phenotypic-detection-of-carbapenemases-particularly-oxa-type-in-enterobacteriaceae-pseudomonas-aeruginosa-and-acinetobacter-spp
#1
Arpasiri Srisrattakarn, Aroonlug Lulitanond, Chotechana Wilailuckana, Nicha Charoensri, Jureerut Daduang, Aroonwadee Chanawong
Objectives: To develop a simple gold nanoparticle (AuNP)-based colorimetric test, GoldNano Carb (GoldC), for detecting carbapenemase production in Gram-negative bacteria, compared with updated Carba NP (CNP) and CarbAcineto NP (CAcNP) tests by using PCR methods as gold standard. Methods: Ninety-nine carbapenemase-producing Enterobacteriaceae (CPE), Pseudomonas spp. and Acinetobacter spp. isolates and 89 non-CPE isolates were tested by the GoldC and CNP. Additionally, the CAcNP was performed in the Acinetobacter spp...
May 23, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/28529797/crystal-structure-of-aqua-trans-bis-dimethyl-sulfoxide-%C3%AE%C2%BAo-pyridine-2-6-di-carboxyl-ato-%C3%AE%C2%BA-3-o-2-n-o-6-nickel-ii
#2
Chen Liu, Ashley C Felts, Daisuke Takahashi, Wesley S Kinden, Khalil A Abboud
In the title complex, [Ni(C7H3NO4)(C2H6OS)2(H2O)], the Ni(II) cation is situated on a twofold rotation axis and exhibits a distorted octa-hedral NO5 coordination environment defined by a tridentate pyridine-2,6-di-carb-oxy-lic acid dianion (dpa(2-)), two dimethyl sulfoxide (DMSO) mol-ecules, and a water mol-ecule. In the crystal, the complex mol-ecules are linked by O-H⋯O and C-H⋯O hydrogen bonds into a three-dimensional network whereby DMSO mol-ecules from neighboring complexes overlap to form layers parallel to (001), alternating with layers of Ni(II)-dpa(2-) moieties...
May 1, 2017: Acta Crystallographica. Section E, Crystallographic Communications
https://www.readbyqxmd.com/read/28508147/identification-of-beta-lactamases-and-beta-lactam-related-proteins-in-human-pathogenic-bacteria-using-a-computational-search-approach
#3
Aniel Jessica Leticia Brambila-Tapia, Ernesto Perez-Rueda, Humberto Barrios, Nory Omayra Dávalos-Rodríguez, Ingrid Patricia Dávalos-Rodríguez, Ernesto Germán Cardona-Muñoz, Mario Salazar-Páramo
A systematic analysis of beta-lactamases based on comparative proteomics has not been performed thus far. In this report, we searched for the presence of beta-lactam-related proteins in 591 bacterial proteomes belonging to 52 species that are pathogenic to humans. The amino acid sequences for 19 different types of beta-lactamases (ACT, CARB, CifA, CMY, CTX, FOX, GES, GOB, IMP, IND, KPC, LEN, OKP, OXA, OXY, SHV, TEM, NDM, and VIM) were obtained from the ARG-ANNOT database and were used to construct 19 HMM profiles, which were used to identify potential beta-lactamases in the completely sequenced bacterial proteomes...
May 16, 2017: Current Microbiology
https://www.readbyqxmd.com/read/28497245/single-species-growth-consuming-inorganic-carbon-with-internal-storage-in-a-poorly-mixed-habitat
#4
Sze-Bi Hsu, King-Yeung Lam, Feng-Bin Wang
This paper presents a PDE system modeling the growth of a single species population consuming inorganic carbon that is stored internally in a poorly mixed habitat. Inorganic carbon takes the forms of "CO2" (dissolved CO2 and carbonic acid) and "CARB" (bicarbonate and carbonate ions), which are substitutable in their effects on algal growth. We first establish a threshold type result on the extinction/persistence of the species in terms of the sign of a principal eigenvalue associated with a nonlinear eigenvalue problem...
May 11, 2017: Journal of Mathematical Biology
https://www.readbyqxmd.com/read/28471427/carb-cutting-works-better-with-a-partner
#5
Jennifer J Kohler
No abstract text is available yet for this article.
May 4, 2017: Nature Structural & Molecular Biology
https://www.readbyqxmd.com/read/28458051/emergence-and-nosocomial-spread-of-carbapenem-resistant-oxa-232-producing-klebsiella-pneumoniae-in-brunei-darussalam
#6
Muhd Haziq Fikry Abdul Momin, Apostolos Liakopoulos, Lynette M Phee, David W Wareham
OBJECTIVES: Carbapenem-resistant Enterobacteriaceae (CRE) are identified as a major global health concern. The success of CRE is facilitated by the emergence, acquisition and spread of successful clones carrying plasmid-encoded resistance genes. In this study, an outbreak of carbapenem-resistant Klebsiella pneumoniae (CRKP) infections in patients hospitalised in Brunei Darussalam was investigated. METHODS: Over a 3-month period (May-July 2015), five multidrug-resistant K...
April 27, 2017: Journal of Global Antimicrobial Resistance
https://www.readbyqxmd.com/read/28435719/crystal-structure-of-o-benzyl-l-tyrosine-n-carb-oxy-anhydride
#7
Aya Inada, Hitoshi Kanazawa
In the title compound, C17H15NO4 (alternative name; O-benzyl-l-tyrosine N-carb-oxy anhydride), the oxazolidine ring is planer, with an r.m.s. deviation of 0.039 Å. The benz-yloxy and benzyl rings are almost coplanar, making a dihedral angle of 0.078 (10)°, and are inclined to the oxazolidine ring by 59.16 (11) and 58.42 (11)°, respectively. In the crystal, mol-ecules are linked by N-H⋯O and C-H⋯O hydrogen bonds, forming ribbons propagating along [010]. The ribbons are linked by C-H⋯π inter-actions, forming a three-dimensional supra-molecular structure...
April 1, 2017: Acta Crystallographica. Section E, Crystallographic Communications
https://www.readbyqxmd.com/read/28435710/inter-action-between-maleic-acid-and-n-r-furfuryl-amines-crystal-structure-of-2-methyl-n-5-phenyl-furan-2-yl-meth-yl-propan-2-aminium-2z-3-carb-oxy-acrylate-and-n-5-iodo-furan-2-yl-meth-yl-2-methyl-propan-2-aminium-2z-3-carb-oxy-prop-2-enoate
#8
Elisaveta A Kvyatkovskaya, Vladimir P Zaytsev, Fedor I Zubkov, Pavel V Dorovatovskii, Yan V Zubavichus, Victor N Khrustalev
The title mol-ecular salts, C15H20NO(+)·C4H3O4(-), (I), and C9H15INO(+)·C4H3O4(-), (II), have very similar mol-ecular geometries for both cation and anion. The anions of both (I) and (II) are practically planar (r.m.s. deviations = 0.062 and 0.072 Å, respectively) and adopt a rare symmetrical geometry with the hy-droxy H atom approximately equidistant from the two O atoms. In their crystals, the cations and anions in both (I) and (II) form tight ionic pairs via strong N-H⋯O hydrogen bonds, with a roughly perpendicular disposition of the anion to the furan ring of the cation...
April 1, 2017: Acta Crystallographica. Section E, Crystallographic Communications
https://www.readbyqxmd.com/read/28433465/dumping-symptoms-is-triggered-by-fat-as-well-as-carbohydrates-in-patients-operated-with-roux-en-y-gastric-bypass
#9
Anna Laurenius, Malin Werling, Carel W le Roux, Lars Fändriks, Torsten Olbers
BACKGROUND: Dumping syndrome after Roux-en-Y gastric bypass (RYGB) is traditionally associated with the consumption of refined carbohydrates, but the role of dietary fat is unclear. OBJECTIVES: This study compares symptoms after consumption of a carbohydrate-rich or fat-rich beverage to determine perceived symptoms, glycemic control, and pulse rate. SETTING: University hospital. METHODS: We assessed perceived symptoms (Sigstad's Dumping Index) and glycemic control (P-glucose and S-insulin) as well as autonomic nervous system activity (reflected by arterial pulse rate) after a standardized liquid meal test (440 kcal/300 mL carbohydrates [CARB] or fat [FAT]) in a randomized crossover blinded setting...
March 1, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28417544/urine-biomarkers-of-acute-kidney-injury-in-noncritically-ill-hospitalized-children-treated-with-chemotherapy
#10
Maya Sterling, Zubaida Al-Ismaili, Kelly R McMahon, Melissa Piccioni, Michael Pizzi, Theresa Mottes, Larry C Lands, Sharon Abish, Adam J Fleming, Michael R Bennett, Ana Palijan, Prasad Devarajan, Stuart L Goldstein, Maureen M O'Brien, Michael Zappitelli
BACKGROUND: Cisplatin (Cis), carboplatin (Carb), and ifosfamide (Ifos) are common nephrotoxic chemotherapies. Biomarkers of tubular injury may allow for early acute kidney injury (AKI) diagnosis. PROCEDURE: We performed a two-center (Canada, United States) pilot study to prospectively measure serum creatinine (SCr), urine neutrophil gelatinase-associated lipocalin (NGAL), and interleukin-18 (IL-18) in children receiving Cis/Carb (27 episodes), Ifos (30 episodes), and in 15 hospitalized, nonchemotherapy patients...
April 18, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28407941/screening-and-identification-of-per-and-polyfluoroalkyl-substances-in-microwave-popcorn-bags
#11
Itsaso Zabaleta, Noelia Negreira, Ekhine Bizkarguenaga, Ailette Prieto, Adrian Covaci, Olatz Zuloaga
Liquid chromatography coupled to quadrupole time-of-flight mass spectrometry (LC-QToF-MS) was used for the accurate identification (<10ppm) of different polyfluoroalkylphosphates (PAPs) and their intermediate and end degradation products in popcorn bags. Up to 46 per- and polyfluoroalkyl substances (PFASs) and precursors were identified. Moreover, an accurate method based on focused ultrasonic solid-liquid extraction (FUSLE) and a clean-up step with Envi-Carb sorbent was validated and applied to the quantification of 24 PFASs in popcorn bags from over twelve European countries, three American countries and two Asian countries...
September 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28396492/the-geometric-framework-for-nutrition-reveals-interactions-between-protein-and-carbohydrate-during-larval-growth-in-honey-bees
#12
Bryan R Helm, Garett Slater, Arun Rajamohan, George D Yocum, Kendra J Greenlee, Julia H Bowsher
In holometabolous insects, larval nutrition affects adult body size, a life history trait with a profound influence on performance and fitness. Individual nutritional components of larval diets are often complex and may interact with one another, necessitating the use of a geometric framework for elucidating nutritional effects. In the honey bee, Apis mellifera, nurse bees provision food to developing larvae, directly moderating growth rates and caste development. However, the eusocial nature of honey bees makes nutritional studies challenging, because diet components cannot be systematically manipulated in the hive...
April 10, 2017: Biology Open
https://www.readbyqxmd.com/read/28316828/crystal-structure-of-%C3%AE-benzyl-dl-aspartate-n-carb-oxyanhydride
#13
Hitoshi Kanazawa, Aya Inada
In the title racemic compound, C12H11NO5 [systematic name: benzyl 2-(2,5-dioxooxazolidin-4-yl)acetate], the oxazolidine ring is planar, with an r.m.s. deviation of 0.03 Å. The benzyl ring is almost normal to the oxazolidine ring, making a dihedral angle of 80.11 (12)°. In the crystal, inversion dimers are formed between the l- and d-enanti-omers via pairs of N-H⋯O hydrogen bonds. This arrangement is favourable for the polymerization of the compound in the solid state. The dimers are linked by C-H⋯O hydrogen bonds, forming layers parallel to the ab plane...
March 1, 2017: Acta Crystallographica. Section E, Crystallographic Communications
https://www.readbyqxmd.com/read/28316800/bis-%C3%AE-benzoato-%C3%AE%C2%BA-2-o-o-bis-benzoato-%C3%AE%C2%BAo-octabutyldi-%C3%AE-3-oxido-tetra-tin-iv
#14
Hans Reuter, Coco K Y A Okio
The asymmetric unit of the title compound, [{Sn(C4H9)2(C6H5COO)}2O]2, consists of two half molecules, completed by application of inversion symmetry. Both mol-ecules adopt a ladder structure typical for this class of dimeric tetra-organodistannoxane di-carboxyl-ates characterized by a centrosymmetric four-membered (Sn-O)2 ring of rhomboidal shape that is extended on both sides by folded six-membered Sn-O-C rings. To a first approximation, both kinds of Sn atoms (Sn i and Sn o ) are trigonal-bipyramidally coordinated...
March 1, 2017: Acta Crystallographica. Section E, Crystallographic Communications
https://www.readbyqxmd.com/read/28288685/ontology-based-literature-mining-of-e-coli-vaccine-associated-gene-interaction-networks
#15
Junguk Hur, Arzucan Özgür, Yongqun He
BACKGROUND: Pathogenic Escherichia coli infections cause various diseases in humans and many animal species. However, with extensive E. coli vaccine research, we are still unable to fully protect ourselves against E. coli infections. To more rational development of effective and safe E. coli vaccine, it is important to better understand E. coli vaccine-associated gene interaction networks. METHODS: In this study, we first extended the Vaccine Ontology (VO) to semantically represent various E...
March 14, 2017: Journal of Biomedical Semantics
https://www.readbyqxmd.com/read/28279669/contribution-of-visuospatial-attention-short-term-memory-and-executive-functions-to-performance-in-number-interval-bisection
#16
Mariagrazia Ranzini, Katia Carbè, Wim Gevers
Number interval bisection consists of estimating the mid-number within a pair (1-9=>5). Healthy adults and right-brain damage patients can show biased performance in this task, underestimating and overestimating the mid-number, respectively. The role of visuospatial attention during this task, and its interplay with other cognitive abilities (e.g., working memory) is still object of debate. In this study we explored the relation between visuospatial attention and individual differences in working memory and executive functions during number interval bisection...
March 6, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28254873/inter-and-intra-observer-agreement-of-fdg-pet-ct-image-interpretation-in-patients-referred-for-assessment-of-cardiac-sarcoidosis
#17
Hiroshi Ohira, Brian Mc Ardle, Robert A deKemp, Pablo B Nery, Daniel Juneau, Jennifer M Renaud, Ran Klein, Owen Clarkin, Karen MacDonald, Eugene Leung, Girish Nair, Rob S B Beanlands, David Birnie
Recent studies have reported the usefulness of (18)F-fluoro-2-deoxyglucose positron emission tomography (FDG-PET) in aiding with the diagnosis and management of patients with cardiac sarcoidosis (CS). However, the image interpretation of FDG-PET for CS is sometimes challenging. We sought to investigate the inter- and intra-observer agreement and explore factors which lead to important discrepancies between readers. METHODS: We studied consecutive patients with no significant coronary artery disease who were referred for assessment of CS...
March 2, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28245965/prevalence-serotyping-and-antimicrobials-resistance-mechanism-of-salmonella-enterica-isolated-from-clinical-and-environmental-samples-in-saudi-arabia
#18
Mohamed A El-Tayeb, Abdelnasser S S Ibrahim, Ali A Al-Salamah, Khalid S Almaary, Yahya B Elbadawi
Salmonella is recognized as a common foodborne pathogen, causing major health problems in Saudi Arabia. Herein, we report epidemiology, antimicrobial susceptibility and the genetic basis of resistance among S. enterica strains isolated in Saudi Arabia. Isolation of Salmonella spp. from clinical and environmental samples resulted in isolation of 33 strains identified as S. enterica based on their biochemical characteristics and 16S-rDNA sequences. S. enterica serovar Enteritidis showed highest prevalence (39...
February 14, 2017: Brazilian Journal of Microbiology: [publication of the Brazilian Society for Microbiology]
https://www.readbyqxmd.com/read/28237518/development-and-validation-of-an-extraction-method-for-the-analysis-of-perfluoroalkyl-substances-in-human-hair
#19
Da-Hye Kim, Jeong-Eun Oh
Human hair has many advantages as a non-invasive sample; however, analytical methods for detecting perfluoroalkyl substances (PFASs) in human hair are still in the development stage. Therefore, the aim of this study was to develop and validate a method for monitoring 11 PFASs in human hair. Solid-phase extraction (SPE), ion-pairing extraction (IPE), a combined method (SPE+IPE) and solvent extraction with ENVI-carb clean-up were compared to develop an optimal extraction method using two types of hair sample (powder and piece forms)...
May 2017: Chemosphere
https://www.readbyqxmd.com/read/28217352/crystal-structure-of-a-chloride-bridged-copper-ii-dimer-piperazine-1-4-dium-bis-di-%C3%AE-chlorido-bis-4-carboxypyridine-2-carboxyl-ato-%C3%AE%C2%BA-2-n-o-2-chlorido-cuprate-ii
#20
Bassey Enyi Inah, Ayi Anyama Ayi, Amit Adhikary
Crystals of a new dimeric chloride-bridged cuprate(II) derived from pyridine-2,4-di-carb-oxy-lic acid were obtained solvothermally in the presence of piperazine and hydro-chloric acid. The crystal structure determination of the title salt, (C4H12N2)[Cu2(C7H4NO4)2Cl4], revealed one of the carboxyl groups of the original pyridine-2,4-di-carb-oxy-lic acid ligand to be protonated, whereas the other is deprotonated and binds together with the pyridine N atom to the Cu(II) atom. The coordination environment of the Cu(II) atom is distorted square-pyramidal...
February 1, 2017: Acta Crystallographica. Section E, Crystallographic Communications
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