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https://www.readbyqxmd.com/read/29791061/antidiuretic-hormone-release-associated-with-increased-intracranial-pressure-independent-of-plasma-osmolality
#1
William J Keller, Elda Mullaj
OBJECTIVE: Introduce and evaluate a new model which explains the release of brain antidiuretic hormone (ADH) independent of plasma osmolality. METHODS: Systematic review and critical analysis of the professional literature. RESULTS: Primary electronic database searches using key terms revealed 57,432 hits. Secondary searches with application of specific inclusion and exclusion criteria and manual inspection for completeness reduced the total number of studies to fourteen (N = 14)...
May 23, 2018: Brain and Behavior
https://www.readbyqxmd.com/read/29779929/prescription-medication-use-and-antinuclear-antibodies-in-the-united-states-1999-2004
#2
Gregg E Dinse, Christine G Parks, Helen C S Meier, Caroll A Co, Edward K L Chan, Todd A Jusko, James Yeh, Frederick W Miller
BACKGROUND: Clinical reports link specific medications with the development of antinuclear antibodies (ANA), but population-based evidence is limited. OBJECTIVE: The present study investigated associations between prescription medication use and ANA in a representative sample of the adult noninstitutionalized US population, first focusing on medications previously related to ANA and then considering all medications reported in the National Health and Nutrition Examination Survey (NHANES)...
May 17, 2018: Journal of Autoimmunity
https://www.readbyqxmd.com/read/29779040/association-between-unexplained-thickened-nuchal-translucency-and-adverse-pregnancy-outcomes
#3
Santee Tiyatha, Sirinart Sirilert, Ratanaporn Sekararithi, Theera Tongsong
OBJECTIVE: To determine the association between unexplained increased nuchal translucency (INT) and adverse pregnancy outcomes. PATIENTS AND METHODS: The prospective database of our fetal down screening project was accessed to retrieve the records with NT measurement and complete follow-up. Pregnancies with pre-existing medical diseases, fetal chromosomal or structural abnormalities were excluded. The selected pregnancies were classified into the INT groups (> 95th percentile), the normal (< 95th percentile) group...
May 19, 2018: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29778387/major-depression-antidepressant-use-and-male-and-female-fertility
#4
Emily A Evans-Hoeker, Esther Eisenberg, Michael P Diamond, Richard S Legro, Ruben Alvero, Christos Coutifaris, Peter R Casson, Gregory M Christman, Karl R Hansen, Heping Zhang, Nanette Santoro, Anne Z Steiner
OBJECTIVE: To determine if maternal major depression (MD), antidepressant use, or paternal MD are associated with pregnancy outcomes after non-IVF fertility treatments. DESIGN: Cohort study. SETTING: Clinics. PATIENT(S): Participants in two randomized trials: PPCOS II (clomiphene citrate versus letrozole for polycystic ovary syndrome), and AMIGOS (gonadotropins versus clomiphene citrate versus letrozole for unexplained infertility)...
May 2018: Fertility and Sterility
https://www.readbyqxmd.com/read/29774423/diagnosis-and-management-of-gynecomastia-for-urologists
#5
REVIEW
Lee Baumgarten, Ali A Dabaja
PURPOSE OF REVIEW: Our aim is to review the steps of diagnosis and management of gynecomastia with a special focus on treatment of gynecomastia associated with androgen deprivation therapy for prostate cancer. RECENT FINDINGS: Recent studies investigating tamoxifen and radiation therapy for both therapy and prophylaxis of bicalutamide-induced gynecomastia are reviewed. Gynecomastia is a common clinical problem, affecting between one and two thirds of middle-aged men...
May 17, 2018: Current Urology Reports
https://www.readbyqxmd.com/read/29767754/mid-luteal-progesterone-a-marker-of-treatment-outcomes-in-couples-with-unexplained-infertility
#6
Karl R Hansen, Esther Eisenberg, Valerie Baker, Micah J Hill, Sixia Chen, Sara Talken, Michael P Diamond, Richard S Legro, Christos Coutifaris, Ruben Alvero, Randal D Robinson, Peter Casson, Gregory M Christman, Nanette Santoro, Heping Zhang, Robert A Wild
Context: Adequate luteal phase progesterone exposure is necessary to induce endometrial changes required for a successful pregnancy outcome. The relationship between low mid-luteal progesterone concentration and the outcome of live birth in ovarian stimulation with intrauterine insemination (OS-IUI) treatments is not defined. Objective: To determine the level of mid-luteal progesterone portending a low chance of live birth following OS-IUI in couples with unexplained infertility...
May 14, 2018: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29766266/-syncope-and-fitness-to-drive
#7
REVIEW
Hermann H Klein
Although medical students are rarely instructed in traffic medicine in Germany, they are obliged to inform their patients about their fitness to drive after having become a medical doctor. This article gives an overview on the fitness to drive for patients with syncope by referring to the driving license regulation and the current guidelines released by the department of traffic. The driving license regulation distinguishes between group 1 and group 2 drivers. Group 1 drivers drive vehicles with a total weight less than 3...
May 15, 2018: Herzschrittmachertherapie & Elektrophysiologie
https://www.readbyqxmd.com/read/29759049/klinefelter-s-syndrome-with-lupus-encephalitis-and-retroperitoneal-teratoma
#8
C Ng Wq, S E Eide, Huang J, Khor Ym
We report a case of a middle-aged male who presented with pyrexia of unknown origin, oral ulcers, rash and bicytopenia. His past medical history included unexplained proteinuria, infertility and joint pain. Initial workup showed a large retroperitoneal soft tissue mass, which has appeared stable for 10 years. He subsequently developed neuropsychiatric symptoms with imaging findings of meningoencephalitis. Concurrent investigations showed elevated ANA, anti-double-stranded DNA (dsDNA) and ESR levels, as well as low complement levels...
January 1, 2018: Lupus
https://www.readbyqxmd.com/read/29752194/sex-specific-relevance-of-diabetes-to-occlusive-vascular-and-other-mortality-a-collaborative-meta-analysis-of-individual-data-from-980-793-adults-from-68-prospective-studies
#9
(no author information available yet)
BACKGROUND: Several studies have shown that diabetes confers a higher relative risk of vascular mortality among women than among men, but whether this increased relative risk in women exists across age groups and within defined levels of other risk factors is uncertain. We aimed to determine whether differences in established risk factors, such as blood pressure, BMI, smoking, and cholesterol, explain the higher relative risks of vascular mortality among women than among men. METHODS: In our meta-analysis, we obtained individual participant-level data from studies included in the Prospective Studies Collaboration and the Asia Pacific Cohort Studies Collaboration that had obtained baseline information on age, sex, diabetes, total cholesterol, blood pressure, tobacco use, height, and weight...
May 8, 2018: Lancet Diabetes & Endocrinology
https://www.readbyqxmd.com/read/29751948/quantifying-positive-communication-doctor-s-language-and-patient-anxiety-in-primary-care-consultations
#10
Inge A Stortenbeker, Juul Houwen, Peter L B J Lucassen, Hugo W Stappers, Willem J J Assendelft, Sandra van Dulmen, Tim C Olde Hartman, Enny Das
OBJECTIVE: Positive communication is advocated for physicians during consultations with patients presenting medically unexplained symptoms (MUS), but studies generally focus on what is said rather than how it is said. This study quantified language use differences of general practitioners (GPs), and assessed their relation to patient anxiety. METHODS: Language use of 18 Dutch GPs during 82 consultations was compared for patients with MUS versus medically explained symptoms (MES)...
May 1, 2018: Patient Education and Counseling
https://www.readbyqxmd.com/read/29746257/novel-pharmacotherapy-in-hypertrophic-cardiomyopathy
#11
Gabriela Andries, Srikanth Yandrapalli, Srihari S Naidu, Julio A Panza
Hypertrophic cardiomyopathy (HCM) is an inherited disease characterized by unexplained left ventricular hypertrophy. Although it is estimated to affect 1 out of 500 people, the HCM gene carrier prevalence is much more common, probably as high as 1 in 200 people. Most affected individuals have a normal life expectancy, while some patients may develop sudden cardiac death or end-stage heart failure. Despite significant developments in the treatment of HCM with surgical, interventional, and device-based procedures, the main focus of current pharmacological therapy has not evolved from the basic objectives of relief of symptoms and improvement in functional capacity...
May 9, 2018: Cardiology in Review
https://www.readbyqxmd.com/read/29745463/therapeutic-implications-of-a-combined-diagnostic-workup-including-endomyocardial-biopsy-in-an-all-comer-population-of-patients-with-heart-failure-a-retrospective-analysis
#12
Efthymios Sotiriou, Susanne Heiner, Thomas Jansen, Moritz Brandt, Kai Helge Schmidt, Karl-Friedrich Kreitner, Tilman Emrich, Heinz-Peter Schultheiss, Eberhard Schulz, Thomas Münzel, Philip Wenzel
BACKGROUND: Aetiology of heart failure (HF) often remains obscure. We therefore evaluated the usefulness of a combined diagnostic approach including cardiac magnetic resonance imaging (CMRI) and endomyocardial biopsy (EMB) to assess the cause of unexplained cardiomyopathy underlying HF. METHODS AND RESULTS: We retrospectively investigated 100 consecutive patients (36% women, mean age 53.6 ± 18.8 years) presenting with unexplained cardiomyopathy (HF with reduced ejection fraction or left ventricular hypertrophy; excluding ischaemic and valvular heart disease; left ventricular ejection fraction 31...
May 10, 2018: ESC Heart Failure
https://www.readbyqxmd.com/read/29739735/effectiveness-of-a-blended-multidisciplinary-intervention-for-patients-with-moderate-medically-unexplained-physical-symptoms-parasol-protocol-for-a-cluster-randomized-clinical-trial
#13
Paula Elisabeth van Westrienen, Martijn F Pisters, Suze Aj Toonders, Marloes Gerrits, Cindy Veenhof, Niek J de Wit
BACKGROUND: Medically unexplained physical symptoms are an important health problem in primary care, with a spectrum from mild to chronic. The burden of chronic medically unexplained physical symptoms is substantial for patients, health care professionals, and society. Therefore, early identification of patients with moderate medically unexplained physical symptoms is needed in order to prevent chronicity. The preventive screening of medically unexplained physical symptoms (PRESUME) screening method was developed using data from the electronic medical record of the patients' general practitioner and demonstrated its prognostic accuracy to identify patients with moderate medically unexplained physical symptoms...
May 8, 2018: JMIR Research Protocols
https://www.readbyqxmd.com/read/29737197/inflammatory-bowel-disease-related-fatigue-is-correlated-with-depression-and-gender
#14
Philip Keightley, Rebecca E Reay, Paul Pavli, Jeffrey Cl Looi
OBJECTIVES: Fatigue is a common and disabling problem in inflammatory bowel disease. We sought to explore the possible determinants of inflammatory bowel disease-associated fatigue including demographic, psychological and disease variables. METHODS: Surveys were distributed to 100 patients undergoing infliximab infusion for inflammatory bowel disease in an infusion lounge, assessing attachment style (Experiences in Close Relationships Revised scale), fatigue (Functional Assessment of Chronic Illness Therapy Fatigue - Fatigue Subscore), and depression and anxiety (Hospital Anxiety and Depression Scale)...
May 1, 2018: Australasian Psychiatry: Bulletin of Royal Australian and New Zealand College of Psychiatrists
https://www.readbyqxmd.com/read/29735386/neurobehavioural-outcome-in-6-18-year-old-children-after-trauma-in-pregnancy-case-control-study
#15
B J van der Knoop, K J Oostrom, I A Zonnenberg, M M van Weissenbruch, R J Vermeulen, J I P de Vries
BACKGROUND: Maternal trauma complicates pregnancy in approximately 7%. Long-term development of children exposed to maternal trauma is unknown. AIM: To determine neurobehavioural outcome of children (6-18 years) born after maternal trauma in pregnancy compared to a matched control group. STUDY DESIGN: Case-control study performed at a tertiary medical centre. SUBJECTS: All consecutive children born after maternal hospitalization for trauma during pregnancy between 1995 and 2005...
April 12, 2018: European Journal of Paediatric Neurology: EJPN
https://www.readbyqxmd.com/read/29726743/opinion-paper-the-role-of-work-in-the-management-of-medically-unexplained-physical-symptoms
#16
Els Tobback, An Mariman, Lies Clauwaert, Lode Godderis, Stefan Heytens, Patrick Ruppol, Daniel Spooren, Rita Tytgat, Martine De Muynck, Dirk Vogelaers
OBJECTIVES: Patients with medically unexplained physical symptoms suffer from chronic fatigue and/or pain in combination with a variety of other symptoms. A flexible, biopsychosocial approach is needed for diagnostic screening and global management. It is crucial to involve the direct patient environment, including family, friends, colleagues as well as health providers, evaluation, and reintegration sector. The aim of this paper is to review the importance of work in the management of medically unexplained physical symptoms...
May 4, 2018: Acta Clinica Belgica
https://www.readbyqxmd.com/read/29726663/-trigger-effect-of-hmg-and-hcg-in-the-treatment-of-unexplainable-non-obstructive-azoospermia
#17
Hao-Rui Hu, Hong-Chuan Nie, Wei-Min Yang, Yuan Sun, Hui Huang, Fang-Gang Xie
Objective: To investigate whether the trigger effect of human menopausal gonadotropins (hMG) and human chorionic gonadotropins (hCG) attributes to the treatment of unexplainable non-obstructive azoospermia (NOA). METHODS: We retrospectively analyzed the clinical data about 282 cases of unexplainable NOA treated in the Maternity and Child Health Hospital of Guizhou Province from January 2010 to May 2017. All the patients underwent trigger treatment by intramuscular injection of hMG at 75 IU 3 times a week for 2 weeks, followed by hCG at 2 000 IU twice a week for another 2 weeks, and meanwhile took vitamin E, Levocarnitine and Tamoxifen as an adjunctive therapy...
September 2017: Zhonghua Nan Ke Xue, National Journal of Andrology
https://www.readbyqxmd.com/read/29724416/acr-appropriateness-criteria-%C3%A2-breast-implant-evaluation
#18
Ana P Lourenco, Linda Moy, Paul Baron, Aarati D Didwania, Roberta M diFlorio, Samantha L Heller, Anna I Holbrook, Alana A Lewin, Tejas S Mehta, Bethany L Niell, Priscilla J Slanetz, Ashley R Stuckey, Daymen S Tuscano, Nina S Vincoff, Susan P Weinstein, Mary S Newell
Breast implant imaging varies depending on patient age, implant type, and symptoms. For asymptomatic patients (any age, any implant), imaging is not recommended. Rupture of saline implants is often clinically evident, as the saline is resorbed and there is a change in breast contour. With saline implants and equivocal clinical findings, ultrasound (US) is the examination of choice for patients less than 30 years of age, either mammography/digital breast tomosynthesis or US may be used for those 30 to 39 years of age, and mammography/digital breast tomosynthesis is used for those 40 years and older...
May 2018: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/29724238/apples-to-apples-can-differences-in-out-of-hospital-cardiac-arrest-incidence-and-outcomes-between-sweden-and-ireland-be-explained-by-core-utstein-variables
#19
Siobhán Masterson, Anneli Strömsöe, John Cullinan, Conor Deasy, Akke Vellinga
BACKGROUND: Variation in reported incidence and outcome based on aggregated data is a persistent feature of out-of-hospital cardiac arrest (OHCA) epidemiology. OBJECTIVE: To investigate the extent to which patient-level analysis using core 'Utstein' variables explains inter-country variation between Sweden and the Republic of Ireland. METHODS: A retrospective cross-sectional comparative study was performed, including all Swedish and Irish OHCA cases attended by Emergency Medical Services (EMS-attended OHCA) where resuscitation was attempted from 1st January 2012 to 31st December 2014...
May 3, 2018: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
https://www.readbyqxmd.com/read/29722753/knowledge-and-attitudes-of-nurses-toward-pressure-injury-prevention-a-cross-sectional-multisite-study
#20
Michelle Barakat-Johnson, Catherine Barnett, Timothy Wand, Kathryn White
PURPOSE: The purpose of the study was to examine the knowledge and attitudes of nurses on pressure injury prevention and determine if there was a relationship between knowledge, attitude, and years of experience following an unexplained increase in reported hospital-acquired pressure injuries across 1 health district in Sydney, Australia. DESIGN: Multisite cross-sectional study. SUBJECTS AND SETTING: Registered and enrolled nurses working in acute, medical, and rehabilitation units in 4 hospitals and 5 community health centers across a local health district...
May 2018: Journal of Wound, Ostomy, and Continence Nursing
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