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Resting state fMRI

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https://www.readbyqxmd.com/read/29235506/differential-contributions-of-the-middle-frontal-gyrus-functional-connectivity-to-literacy-and-numeracy
#1
Maki S Koyama, David O'Connor, Zarrar Shehzad, Michael P Milham
Literacy and numeracy equally affect an individual's success in and beyond schools, but these two competencies tend to be separately examined, particularly in neuroimaging studies. The current resting-state fMRI study examined the neural correlates of literacy and numeracy in the same sample of healthy adults. We first used an exploratory "Multivariate Distance Matrix Regression" (MDMR) approach to examine intrinsic functional connectivity (iFC), highlighting the middle frontal gyrus (MFG) for both competencies...
December 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29234091/structural-reorganization-of-the-early-visual-cortex-following-braille-training-in-sighted-adults
#2
Łukasz Bola, Katarzyna Siuda-Krzywicka, Małgorzata Paplińska, Ewa Sumera, Maria Zimmermann, Katarzyna Jednoróg, Artur Marchewka, Marcin Szwed
Training can induce cross-modal plasticity in the human cortex. A well-known example of this phenomenon is the recruitment of visual areas for tactile and auditory processing. It remains unclear to what extent such plasticity is associated with changes in anatomy. Here we enrolled 29 sighted adults into a nine-month tactile Braille-reading training, and used voxel-based morphometry and diffusion tensor imaging to describe the resulting anatomical changes. In addition, we collected resting-state fMRI data to relate these changes to functional connectivity between visual and somatosensory-motor cortices...
December 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29228204/decreased-resting-state-interhemispheric-functional-connectivity-correlated-with-neurocognitive-deficits-in-drug-naive-first-episode-adolescent-onset-schizophrenia
#3
Yi Liu, Yan Zhang, Luxian Lv, Feihu Hu, Renrong Wu, Jingping Zhao, Wenbin Guo
Background: Given that adolescence is a critical epoch in the onset of schizophrenia, studying aberrant brain changes in adolescent-onset schizophrenia (AOS), particularly in patients with drug-naive first-episode schizophrenia, is important to understand the biological mechanism of this disorder. Previous resting-state functional magnetic resonance imaging (fMRI) studies have shown abnormal functional connectivity in separate hemispheres in patients with adult-onset schizophrenia. Our aim to study AOS can provide clues for the early aetiology of schizophrenia...
November 7, 2017: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/29227148/structural-abnormalities-and-altered-regional-brain-activity-in-multiple-sclerosis-with-simple-spinal-cord-involvement
#4
Ping Yin, Yi Liu, Hua Xiong, Yongliang Han, Shambhu Kumar Sah, Chun Zeng, Jingjie Wang, Yongmei Li
OBJECTIVE: To assess the changes of the structural and functional abnormalities in multiple sclerosis with simple spinal cord involvement (MS-SSCI) by using resting-state functional magnetic resonance imaging (RS-fMRI), voxel based morphology (VBM) and diffusion tensor tractography. METHODS: The amplitude of low-frequency fluctuation (ALFF) of 22 patients with MS-SSCI and 22 healthy controls (HCs) matched for age, gender and education were compared by using RS-fMRI...
December 11, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/29226689/simultaneous-multi-slice-resting-state-fmri-at-3-tesla-slice-acceleration-related-biases-in-physiological-effects
#5
Ali M Golestani, Zahra Faraji-Dana, M Aras Kayvanrad, Kawin Setsompop, Simon Graham, J Jean Chen
Simultaneous multi-slice echo-planar imaging (EPI) can enhance the spatiotemporal resolution of resting-state functional MRI (rs-fMRI) by encoding and simultaneously imaging "groups" of slices. However, phenomena including respiration, cardiac pulsatility, respiration volume per time (RVT) and cardiac-rate variation (CRV), referred to as "physiological processes", impact SMS-EPI rs-fMRI in a manner that has yet to be well characterized. In particular, physiological noise may incur aliasing and introduce spurious signals from one slice into another within the "slice-group" in rs-fMRI data, resulting in a deleterious effect on resting-state functional connectivity MRI (rs-fcMRI) maps...
December 10, 2017: Brain Connectivity
https://www.readbyqxmd.com/read/29226283/improving-functional-mri-registration-using-whole-brain-functional-correlation-tensors
#6
Yujia Zhou, Pew-Thian Yap, Han Zhang, Lichi Zhang, Qianjin Feng, Dinggang Shen
Population studies of brain function with resting-state functional magnetic resonance imaging (rs-fMRI) largely rely on the accurate inter-subject registration of functional areas. This is typically achieved through registration of the corresponding T1-weighted MR images with more structural details. However, accumulating evidence has suggested that such strategy cannot well-align functional regions which are not necessarily confined by the anatomical boundaries defined by the T1-weighted MR images. To mitigate this problem, various registration algorithms based directly on rs-fMRI data have been developed, most of which have utilized functional connectivity (FC) as features for registration...
September 2017: Medical Image Computing and Computer-assisted Intervention: MICCAI ..
https://www.readbyqxmd.com/read/29225975/correlation-between-traits-of-emotion-based-impulsivity-and-intrinsic-default-mode-network-activity
#7
Jizheng Zhao, Dardo Tomasi, Corinde E Wiers, Ehsan Shokri-Kojori, Şükrü B Demiral, Yi Zhang, Nora D Volkow, Gene-Jack Wang
Negative urgency (NU) and positive urgency (PU) are implicated in several high-risk behaviors, such as eating disorders, substance use disorders, and nonsuicidal self-injury behavior. The current study aimed to explore the possible link between trait of urgency and brain activity at rest. We assessed the amplitude of low-frequency fluctuations (ALFF) of the resting-state functional magnetic resonance imaging (fMRI) signal in 85 healthy volunteers. Trait urgency measures were related to ALFF in the lateral orbitofrontal cortex, dorsolateral prefrontal cortex, ventral and dorsal medial frontal cortex, anterior cingulate, and posterior cingulate cortex/precuneus...
2017: Neural Plasticity
https://www.readbyqxmd.com/read/29224727/high-resolution-cbv-fmri-allows-mapping-of-laminar-activity-and-connectivity-of-cortical-input-and-output-in-human-m1
#8
Laurentius Huber, Daniel A Handwerker, David C Jangraw, Gang Chen, Andrew Hall, Carsten Stüber, Javier Gonzalez-Castillo, Dimo Ivanov, Sean Marrett, Maria Guidi, Jozien Goense, Benedikt A Poser, Peter A Bandettini
Layer-dependent fMRI allows measurements of information flow in cortical circuits, as afferent and efferent connections terminate in different cortical layers. However, it is unknown to what level human fMRI is specific and sensitive enough to reveal directional functional activity across layers. To answer this question, we developed acquisition and analysis methods for blood-oxygen-level-dependent (BOLD) and cerebral-blood-volume (CBV)-based laminar fMRI and used these to discriminate four different tasks in the human motor cortex (M1)...
December 6, 2017: Neuron
https://www.readbyqxmd.com/read/29223933/task-based-and-resting-state-fmri-reveal-compensatory-network-changes-following-damage-to-left-inferior-frontal-gyrus
#9
Glyn P Hallam, Hannah E Thompson, Mark Hymers, Rebecca E Millman, Jennifer M Rodd, Matthew A Lambon Ralph, Jonathan Smallwood, Elizabeth Jefferies
Damage to left inferior prefrontal cortex in stroke aphasia is associated with semantic deficits reflecting poor control over conceptual retrieval, as opposed to loss of knowledge. However, little is known about how functional recruitment within the semantic network changes in patients with executive-semantic deficits. The current study acquired functional magnetic resonance imaging (fMRI) data from 14 patients with semantic aphasia, who had difficulty with flexible semantic retrieval following left prefrontal damage, and 16 healthy age-matched controls, allowing us to examine activation and connectivity in the semantic network...
October 17, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/29223742/network-analysis-reveals-disrupted-functional-brain-circuitry-in-drug-naive-social-anxiety-disorder
#10
REVIEW
Xun Yang, Jin Liu, Yajing Meng, Mingrui Xia, Zaixu Cui, Xi Wu, Xinyu Hu, Wei Zhang, Gaolang Gong, Qiyong Gong, John A Sweeney, Yong He
Social anxiety disorder (SAD) is a common and disabling condition characterized by excessive fear and avoidance of public scrutiny. Neuroimaging studies have suggested that the emotional and behavior deficits in SAD are associated with abnormalities in regional brain function and functional connectivity. However, little is known about whether intrinsic functional brain networks in patients with SAD are topologically disrupted. Here, we collected resting-state fMRI data from 33 drug-naive patients with SAD and 32 healthy controls (HC), constructed functional networks with 34 predefined regions based on previous meta-analytic research with task-based fMRI in SAD, and performed network-based statistic and graph-theory analyses...
December 6, 2017: NeuroImage
https://www.readbyqxmd.com/read/29222835/effective-network-of-deep-brain-stimulation-of-subthalamic-nucleus-with-bimodal-positron-emission-tomography-functional-magnetic-resonance-imaging-in-parkinson-s-disease
#11
Hui-Min Chen, Zhi-Qiang Sha, Hui-Zi Ma, Yong He, Tao Feng
AIMS: Deep brain stimulation of the subthalamic nucleus (STN-DBS) has become an effective treatment strategy for patients with Parkinson's disease. However, the biological mechanism underlying DBS treatment remains poorly understood. METHOD: In this study, we investigated how STN-DBS modulated the brain network using a bimodal positron emission tomography (PET)/functional magnetic resonance imaging (fMRI) dataset. We first performed an activation likelihood estimation meta-analysis of 13 PET/SPECT studies concerning STN-DBS effects on resting-state brain activity in Parkinson's disease...
December 8, 2017: CNS Neuroscience & Therapeutics
https://www.readbyqxmd.com/read/29218892/heritability-estimates-on-resting-state-fmri-data-using-enigma-analysis-pipeline
#12
Bhim M Adhikari, Neda Jahanshad, Dinesh Shukla, David C Glahn, John Blangero, Richard C Reynolds, Robert W Cox, Els Fieremans, Jelle Veraart, Dmitry S Novikov, Thomas E Nichols, L Elliot Hong, Paul M Thompson, Peter Kochunov
Big data initiatives such as the Enhancing NeuroImaging Genetics through Meta-Analysis consortium (ENIGMA), combine data collected by independent studies worldwide to achieve more generalizable estimates of effect sizes and more reliable and reproducible outcomes. Such efforts require harmonized image analyses protocols to extract phenotypes consistently. This harmonization is particularly challenging for resting state fMRI due to the wide variability of acquisition protocols and scanner platforms; this leads to site-to-site variance in quality, resolution and temporal signal-to-noise ratio (tSNR)...
2018: Pacific Symposium on Biocomputing
https://www.readbyqxmd.com/read/29213031/-neuronet-restructuring-in-focal-and-generalized-epilepsy-according-to-resting-state-fmri
#13
L A Mayorova, I S Samotaeva, N N Lebedeva, R V Luzin, V V Gaskin, F K Rider, A M Teplyshova, R G Akzhigitov, A B Guekht
AIM: To compare neuronet restructuring in focal and generalized epilepsy. MATERIAL AND METHODS: Seventy-seven patients, aged from 18 to 65 years, with the diagnosis of epilepsy, including 63 patients with focal epilepsy and 14 with generalized epilepsy, were examined. A control group included 23 healthy people. Neuronet restructuring was studied using fMRI. RESULTS AND CONCLUSION: According to resting state fMRI, there were between-group differences in spatial organization (activity map) of the brain structures as well as in the results of cross-correlation analysis of interaction maps of resting-state networks...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/29211655/spectral-diversity-in-default-mode-network-connectivity-reflects-behavioral-state
#14
Michael M Craig, Anne E Manktelow, Barbara J Sahakian, David K Menon, Emmanuel A Stamatakis
Default mode network (DMN) functional connectivity is thought to occur primarily in low frequencies (<0.1 Hz), resulting in most studies removing high frequencies during data preprocessing. In contrast, subtractive task analyses include high frequencies, as these are thought to be task relevant. An emerging line of research explores resting fMRI data at higher-frequency bands, examining the possibility that functional connectivity is a multiband phenomenon. Furthermore, recent studies suggest DMN involvement in cognitive processing; however, without a systematic investigation of DMN connectivity during tasks, its functional contribution to cognition cannot be fully understood...
December 6, 2017: Journal of Cognitive Neuroscience
https://www.readbyqxmd.com/read/29210942/auditory-related-resting-state-fmri-functional-connectivity-in-tinnitus-patients-tinnitus-diagnosis-performance
#15
Shujiro B Minami, Naoki Oishi, Takahisa Watabe, Kimiichi Uno, Kaoru Ogawa
OBJECTIVE: The purpose of the present study was to investigate functional connectivity in tinnitus patients with and without hearing loss, and design the tinnitus diagnosis performance by resting state functional magnetic resonance imaging (rs-fMRI). SUBJECTS AND METHODS: Nineteen volunteers with normal hearing without tinnitus, 18 tinnitus patients with hearing loss, and 11 tinnitus patients without hearing loss were enrolled in this study. The subjects were evaluated with rs-fMRI, and region of interests (ROIs) based correlation analyses were performed using the CONN toolbox version 16 and SPM version 8...
November 28, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/29209234/altered-brain-functional-connectivity-in-betel-quid-dependent-chewers
#16
Xiaojun Huang, Weidan Pu, Haihong Liu, Xinmin Li, Andrew J Greenshaw, Serdar M Dursun, Zhimin Xue, Zhening Liu
Background: Betel quid (BQ) is a common psychoactive substance worldwide with particularly high usage in many Asian countries. This study aimed to explore the effect of BQ use on functional connectivity by comparing global functional brain networks and their subset between BQ chewers and healthy controls (HCs). Methods: Resting-state functional magnetic resonance imaging (fMRI) was obtained from 24 betel quid-dependent (BQD) male chewers and 27 healthy male individuals on a 3...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29209199/decreased-complexity-in-alzheimer-s-disease-resting-state-fmri-evidence-of-brain-entropy-mapping
#17
Bin Wang, Yan Niu, Liwen Miao, Rui Cao, Pengfei Yan, Hao Guo, Dandan Li, Yuxiang Guo, Tianyi Yan, Jinglong Wu, Jie Xiang, Hui Zhang
Alzheimer's disease (AD) is a frequently observed, irreversible brain function disorder among elderly individuals. Resting-state functional magnetic resonance imaging (rs-fMRI) has been introduced as an alternative approach to assessing brain functional abnormalities in AD patients. However, alterations in the brain rs-fMRI signal complexities in mild cognitive impairment (MCI) and AD patients remain unclear. Here, we described the novel application of permutation entropy (PE) to investigate the abnormal complexity of rs-fMRI signals in MCI and AD patients...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/29209197/asymmetry-of-hemispheric-network-topology-reveals-dissociable-processes-between-functional-and-structural-brain-connectome-in-community-living-elders
#18
Yu Sun, Junhua Li, John Suckling, Lei Feng
Human brain is structurally and functionally asymmetrical and the asymmetries of brain phenotypes have been shown to change in normal aging. Recent advances in graph theoretical analysis have showed topological lateralization between hemispheric networks in the human brain throughout the lifespan. Nevertheless, apparent discrepancies of hemispheric asymmetry were reported between the structural and functional brain networks, indicating the potentially complex asymmetry patterns between structural and functional networks in aging population...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/29209186/the-neural-association-between-tendency-to-forgive-and-spontaneous-brain-activity-in-healthy-young-adults
#19
Haijiang Li, Jiamei Lu
The tendency to forgive (TTF) refers to one's global dispositional level of forgiveness across situations and relationships. Previous brain imaging studies examined activation patterns underlying forgiving process, yet the association between individual differences in the TTF and spontaneous brain activity at resting-state remains unknown. In this study, resting-state functional magnetic resonance imaging (fMRI) was used to investigate the correlation between the TTF and spontaneous brain activity in a young adult sample...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/29208569/a-digital-3d-atlas-of-the-marmoset-brain-based-on-multi-modal-mri
#20
Cirong Liu, Frank Q Ye, Cecil Chern-Chyi Yen, John D Newman, Daniel Glen, David A Leopold, Afonso C Silva
The common marmoset (Callithrix jacchus) is a New-World monkey of growing interest in neuroscience. Magnetic resonance imaging (MRI) is an essential tool to unveil the anatomical and functional organization of the marmoset brain. To facilitate identification of regions of interest, it is desirable to register MR images to an atlas of the brain. However, currently available atlases of the marmoset brain are mainly based on 2D histological data, which are difficult to apply to 3D imaging techniques. Here, we constructed a 3D digital atlas based on high-resolution ex-vivo MRI images, including magnetization transfer ratio (a T1-like contrast), T2w images, and multi-shell diffusion MRI...
December 2, 2017: NeuroImage
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