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Povidone iodine versus chlorhexidine

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https://www.readbyqxmd.com/read/27778318/oral-hygiene-care-for-critically-ill-patients-to-prevent-ventilator-associated-pneumonia
#1
REVIEW
Fang Hua, Huixu Xie, Helen V Worthington, Susan Furness, Qi Zhang, Chunjie Li
BACKGROUND: Ventilator-associated pneumonia (VAP) is defined as pneumonia developing in people who have received mechanical ventilation for at least 48 hours. VAP is a potentially serious complication in these patients who are already critically ill. Oral hygiene care (OHC), using either a mouthrinse, gel, toothbrush, or combination, together with aspiration of secretions, may reduce the risk of VAP in these patients. OBJECTIVES: To assess the effects of oral hygiene care on incidence of ventilator-associated pneumonia in critically ill patients receiving mechanical ventilation in hospital intensive care units (ICUs)...
October 25, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27410189/skin-antisepsis-for-reducing-central-venous-catheter-related-infections
#2
REVIEW
Nai Ming Lai, Nai An Lai, Elizabeth O'Riordan, Nathorn Chaiyakunapruk, Jacqueline E Taylor, Kenneth Tan
BACKGROUND: The central venous catheter (CVC) is a device used for many functions, including monitoring haemodynamic indicators and administering intravenous medications, fluids, blood products and parenteral nutrition. However, as a foreign object, it is susceptible to colonisation by micro-organisms, which may lead to catheter-related blood stream infection (BSI) and in turn, increased mortality, morbidities and health care costs. OBJECTIVES: To assess the effects of skin antisepsis as part of CVC care for reducing catheter-related BSIs, catheter colonisation, and patient mortality and morbidities...
July 13, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27129749/the-effects-of-surgical-hand-scrubbing-protocols-on-skin-integrity-and-surgical-site-infection-rates-a-systematic-review
#3
Liang Qin Liu, Sinead Mehigan
This systematic review aimed to critically appraise and synthesize updated evidence regarding the effect of surgical-scrub techniques on skin integrity and the incidence of surgical site infections. Databases searched include the Cumulative Index to Nursing and Allied Health Literature, MEDLINE, Embase, and Cochrane Central. Our review was limited to eight peer-reviewed, randomized controlled trials and two nonrandomized controlled trials published in English from 1990 to 2015. Comparison models included traditional hand scrubbing with chlorhexidine gluconate or povidone-iodine against alcohol-based hand rubbing, scrubbing with a brush versus without a brush, and detergent-based antiseptics alone versus antiseptics incorporating alcohol solutions...
May 2016: AORN Journal
https://www.readbyqxmd.com/read/27038101/antimicrobial-efficiency-of-mouthrinses-versus-and-in-combination-with-different-photodynamic-therapies-on-periodontal-pathogens-in-an-experimental-study
#4
E-M Decker, V Bartha, A Kopunic, C von Ohle
BACKGROUND AND OBJECTIVE: In the therapy of destructive periodontal disease, chemical antimicrobial agents and increasingly photodynamic therapy (PDT) play an important adjunctive role to standard mechanical anti-infective treatment procedures. However, both antiseptic methods have their shortcomings in terms of eliminating periodontal pathogens. The aim of the study was to compare the antibacterial efficacy of different antiseptic mouthrinses, of a conventional and a new, modified PDT(plus) as well as of the different antiseptic mouthrinses combined with either the conventional or the modified PDT(plus) against periopathogens...
April 1, 2016: Journal of Periodontal Research
https://www.readbyqxmd.com/read/27007217/antimicrobial-dressings-for-the-prevention-of-catheter-related-infections-in-newborn-infants-with-central-venous-catheters
#5
REVIEW
Nai Ming Lai, Jacqueline E Taylor, Kenneth Tan, Yao Mun Choo, Azanna Ahmad Kamar, Nor Asiah Muhamad
BACKGROUND: Central venous catheters (CVCs) provide secured venous access in neonates. Antimicrobial dressings applied over the CVC sites have been proposed to reduce catheter-related blood stream infection (CRBSI) by decreasing colonisation. However, there may be concerns on the local and systemic adverse effects of these dressings in neonates. OBJECTIVES: We assessed the effectiveness and safety of antimicrobial (antiseptic or antibiotic) dressings in reducing CVC-related infections in newborn infants...
March 23, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/26799160/surgical-hand-antisepsis-to-reduce-surgical-site-infection
#6
REVIEW
Judith Tanner, Jo C Dumville, Gill Norman, Mathew Fortnam
BACKGROUND: Medical professionals routinely carry out surgical hand antisepsis before undertaking invasive procedures to destroy transient micro-organisms and inhibit the growth of resident micro-organisms. Antisepsis may reduce the risk of surgical site infections (SSIs) in patients. OBJECTIVES: To assess the effects of surgical hand antisepsis on preventing surgical site infections (SSIs) in patients treated in any setting. The secondary objective is to determine the effects of surgical hand antisepsis on the numbers of colony-forming units (CFUs) of bacteria on the hands of the surgical team...
2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/26660045/evaluation-of-catheter-infection-rates-in-converted-dialysis-catheters-versus-de-novo-placement-in-the-setting-of-chlorhexidine-use
#7
Jared M Criddle, Robert A Hieb, Sarah B White, Parag J Patel, Eric J Hohenwalter, Sean M Tutton, William S Rilling
PURPOSE: Prior studies have reported infection rates of converting non-tunneled dialysis catheters (NTDCs) to tunneled dialysis catheters (TDCs) versus de novo placement of TDCs using povidone-iodine. Chlorhexidine, per the Center of Disease Control guidelines, has been exclusively used in our institution since 2005. Therefore, our study aims to determine whether there is a difference in infection rates between conversion and de novo placement when utilizing chlorhexidine. MATERIALS AND METHODS: A retrospective analysis from 1/1/2009 to 8/10/2012 was performed of patients who underwent placement of NTDCs, which were subsequently converted to TDCs and those who underwent de novo TDC placement...
March 2016: Journal of Vascular Access
https://www.readbyqxmd.com/read/26388532/skin-antisepsis-with-chlorhexidine-alcohol-versus-povidone-iodine-alcohol-with-and-without-skin-scrubbing-for-prevention-of-intravascular-catheter-related-infection-clean-an-open-label-multicentre-randomised-controlled-two-by-two-factorial-trial
#8
RANDOMIZED CONTROLLED TRIAL
Olivier Mimoz, Jean-Christophe Lucet, Thomas Kerforne, Julien Pascal, Bertrand Souweine, Véronique Goudet, Alain Mercat, Lila Bouadma, Sigismond Lasocki, Serge Alfandari, Arnaud Friggeri, Florent Wallet, Nicolas Allou, Stéphane Ruckly, Dorothée Balayn, Alain Lepape, Jean-François Timsit
BACKGROUND: Intravascular-catheter-related infections are frequent life-threatening events in health care, but incidence can be decreased by improvements in the quality of care. Optimisation of skin antisepsis is essential to prevent short-term catheter-related infections. We hypothesised that chlorhexidine-alcohol would be more effective than povidone iodine-alcohol as a skin antiseptic to prevent intravascular-catheter-related infections. METHODS: In this open-label, randomised controlled trial with a two-by-two factorial design, we enrolled consecutive adults (age ≥18 years) admitted to one of 11 French intensive-care units and requiring at least one of central-venous, haemodialysis, or arterial catheters...
November 21, 2015: Lancet
https://www.readbyqxmd.com/read/26258558/the-combined-impact-of-surgical-team-education-and-chlorhexidine-2-alcohol-on-the-reduction-of-surgical-site-infection-following-cardiac-surgery
#9
Margaret M Hannan, Katie E O'Sullivan, Ann M Higgins, Ann-Marie Murphy, James McCarthy, Edmund Ryan, John P Hurley
BACKGROUND: The use of 2% chlorhexidine in 70% alcohol (CHG) has been associated with reduction in catheter-related bloodstream infections and surgical site infection (SSI) in general surgery. Also, improved awareness of best practice from the perspective of the operative team is likely to result in reductions in SSI rates. METHODS: This is an ambispective cohort study of patients undergoing elective cardiac surgery. Between January 2010 and December 2010, patients underwent surgical preparation using Alcohol Povidone Iodine (API)...
December 2015: Surgical Infections
https://www.readbyqxmd.com/read/25381486/comparison-of-the-efficacy-of-chlorhexidine-gluconate-versus-povidone-iodine-as-preoperative-skin-preparation-for-the-prevention-of-surgical-site-infections-in-clean-contaminated-upper-abdominal-surgeries
#10
RANDOMIZED CONTROLLED TRIAL
Anirudh Srinivas, Lileswar Kaman, Prithivi Raj, Vikas Gautam, Divya Dahiya, Gurpreet Singh, Rajinder Singh, Bikash Medhi
PURPOSE: To compare the efficacy of chlorhexidine-gluconate versus povidone iodine in preoperative skin preparation in the prevention of surgical site infections (SSIs) in clean-contaminated upper abdominal surgeries. METHODS: This was a prospective randomized controlled trial conducted on patients undergoing clean-contaminated upper abdominal surgeries. A total of 351 patients 18-70 years old were randomized into two groups; chlorhexidine and povidone iodine skin preparation before surgery...
November 2015: Surgery Today
https://www.readbyqxmd.com/read/25229700/skin-preparation-for-preventing-infection-following-caesarean-section
#11
REVIEW
Diah R Hadiati, Mohammad Hakimi, Detty S Nurdiati, Erika Ota
BACKGROUND: The risk of maternal mortality and morbidity (particularly postoperative infection) is higher for caesarean section than for vaginal birth. With the increasing rate of caesarean section, it is important that the risks to the mother are minimised as far as possible. This review focuses on different forms and methods for preoperative skin preparation to prevent infection. OBJECTIVES: To compare the effects of different agent forms and methods of preoperative skin preparation for preventing postcaesarean infection...
2014: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/24849000/chlorhexidine-gluconate-versus-povidone-iodine-at-cesarean-delivery-a-randomized-controlled-trial
#12
RANDOMIZED CONTROLLED TRIAL
Cynelle M Kunkle, Jennifer Marchan, Sara Safadi, Stephanie Whitman, Ramen H Chmait
BACKGROUND/AIMS: To compare the prevalence of positive bacterial cultures at the cesarean delivery (CD) incision site in patients with pre-operative application of chlorhexidine gluconate (CG) versus povidone iodine (PI). METHODS: Women undergoing a scheduled CD at ≥36 gestational weeks were randomly assigned to receive CG or PI. A swab of the incision site was performed at 3 min after disinfectant application and at 18 post-operative hours, and the prevalence of cultures with any detected bacterial growth was compared for the two groups...
March 2015: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/24476018/efficacy-of-pre-operative-nasal-staphylococcus-aureus-screening-and-chlorhexidine-chest-scrub-in-decreasing-the-incidence-of-post-resection-empyema
#13
Laura E Grimmer, Todd S Stafford, Steven Milman, Thomas Ng
BACKGROUND: We evaluated the efficacy of pre-operative Staphylococcus aureus (SA) screening and chlorhexidine chest scrub in decreasing the incidence of empyema after major pulmonary resections. METHODS: For two years, a strategy aimed at decreasing post-resection empyema was instituted. This entailed pre-operative screening for nasal SA and chlorhexidine chest scrub the night before surgery (Group Swab-Scrub, n=192). Patients screened positive for SA, methicillin-resistant (MRSA) and methicillin-sensitive (MSSA), received 5 d of nasal mupirocin...
April 2014: Surgical Infections
https://www.readbyqxmd.com/read/24408354/antibiotics-and-antiseptics-for-venous-leg-ulcers
#14
REVIEW
Susan O'Meara, Deyaa Al-Kurdi, Yemisi Ologun, Liza G Ovington, Marrissa Martyn-St James, Rachel Richardson
BACKGROUND: Venous leg ulcers are a type of chronic wound affecting up to 1% of adults in developed countries at some point during their lives. Many of these wounds are colonised by bacteria or show signs of clinical infection. The presence of infection may delay ulcer healing. Two main strategies are used to prevent and treat clinical infection in venous leg ulcers: systemic antibiotics and topical antibiotics or antiseptics. OBJECTIVES: The objective of this review was to determine the effects of systemic antibiotics and topical antibiotics and antiseptics on the healing of venous ulcers...
January 10, 2014: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/24363048/antibiotics-and-antiseptics-for-venous-leg-ulcers
#15
REVIEW
Susan O'Meara, Deyaa Al-Kurdi, Yemisi Ologun, Liza G Ovington, Marrissa Martyn-St James, Rachel Richardson
BACKGROUND: Venous leg ulcers are a type of chronic wound affecting up to 1% of adults in developed countries at some point during their lives. Many of these wounds are colonised by bacteria or show signs of clinical infection. The presence of infection may delay ulcer healing. Two main strategies are used to prevent and treat clinical infection in venous leg ulcers: systemic antibiotics and topical antibiotics or antiseptics. OBJECTIVES: The objective of this review was to determine the effects of systemic antibiotics and topical antibiotics and antiseptics on the healing of venous ulcers; review authors also examined the effects of these interventions on clinical infection, bacterial flora, bacterial resistance, ulcer recurrence, adverse effects, patient satisfaction, health-related quality of life and costs...
2013: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/24071682/oral-hygiene-regimes-for-mechanically-ventilated-patients-that-use-chlorhexidine-reduce-ventilator-associated-pneumonia
#16
COMMENT
Derek Richards
DATA SOURCES: The Cochrane Oral Health Group's Trials Register, the Cochrane Central Register of Controlled Trials (CENTRAL), Medline, Embase, CINAHL, LILACS, Chinese Biomedical Literature Database, China National Knowledge Infrastructure, Wan Fang Database, OpenGrey and ClinicalTrials.gov databases were searched. Reference lists of identified articles were also scanned for relevant papers. There were no language restrictions. STUDY SELECTION: Randomised controlled trials (RCTs) evaluating OHC in the form of mouthwashes, swabs, toothbrushing or in combination in critically ill patients receiving mechanical ventilation were included...
September 2013: Evidence-based Dentistry
https://www.readbyqxmd.com/read/23939759/oral-hygiene-care-for-critically-ill-patients-to-prevent-ventilator-associated-pneumonia
#17
REVIEW
Zongdao Shi, Huixu Xie, Ping Wang, Qi Zhang, Yan Wu, E Chen, Linda Ng, Helen V Worthington, Ian Needleman, Susan Furness
BACKGROUND: Ventilator-associated pneumonia (VAP) is defined as pneumonia developing in persons who have received mechanical ventilation for at least 48 hours. VAP is a potentially serious complication in these patients who are already critically ill. Oral hygiene care (OHC), using either a mouthrinse, gel, toothbrush, or combination, together with aspiration of secretions may reduce the risk of VAP in these patients. OBJECTIVES: To assess the effects of OHC on the incidence of VAP in critically ill patients receiving mechanical ventilation in intensive care units (ICUs) in hospitals...
2013: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/23744839/risk-factors-for-the-development-of-catheter-related-bloodstream-infections-in-patients-receiving-home-parenteral-nutrition
#18
Alan L Buchman, Marianne Opilla, Mary Kwasny, Thomas G Diamantidis, Rodney Okamoto
BACKGROUND: Risk factors for development of catheter-related bloodstream infections (CRBSI) were studied in 125 adults and 18 children who received home parenteral nutrition (HPN). METHODS: Medical records from a national home care pharmacy were reviewed for all patients that had HPN infused at least twice weekly for a minimum of two years from January 1, 2006-December 31, 2011. Infection and risk factor data were collected during this time period on all patients although those patients who received HPN for a longer period had data collected since initiation of HPN...
August 2014: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/23611598/can-we-reduce-the-surgical-site-infection-rate-in-cesarean-sections-using-a-chlorhexidine-based-antisepsis-protocol
#19
Jonia Amer-Alshiek, Tahani Alshiek, Benny Almog, Joseph B Lessing, Abed Satel, Ariel Many, Ishai Levin
OBJECTIVE: To determine whether chlorhexidine-based antisepsis reduces the rate of surgical site infections (SSIs) in elective and non-elective cesarean sections (CS) compared with povidone-iodine protocol. METHODS: This was a retrospective study. Women undergoing elective and non-elective CS during two periods of time who were treated with two different antisepsis protocols were included. The protocols for antisepsis were povidone-iodine 10% scrub followed by 10% povidone-iodine in 65% alcohol (n = 163) and chlorhexidine 2% followed by 70% alcohol (n = 163)...
November 2013: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/23164373/a-comparison-of-chlorhexidine-alcohol-versus-povidone-iodine-for-eliminating-skin-flora-before-genitourinary-prosthetic-surgery-a-randomized-controlled-trial
#20
RANDOMIZED CONTROLLED TRIAL
Lawrence L Yeung, Shaun Grewal, Arnold Bullock, H Henry Lai, Steven B Brandes
PURPOSE: We defined the relevant skin flora during genitourinary prosthetic surgery, evaluated the safety of chlorhexidine-alcohol for use on the male genitalia and compared chlorhexidine-alcohol to povidone-iodine in decreasing the rate of positive bacterial skin cultures at the surgical skin site before prosthetic device implantation. MATERIALS AND METHODS: In this single institution, prospective, randomized, controlled study we evaluated 100 consecutive patients undergoing initial genitourinary prosthetic implantation...
January 2013: Journal of Urology
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