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ring segment cornea

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https://www.readbyqxmd.com/read/29594793/sterile-keratitis-after-uneventful-corneal-collagen-cross-linking-in-a-patient-with-axenfeld-rieger-syndrome
#1
Betul Seher Uysal, Derya Yaman, Ozge Sarac, Emine Akcay, Nurullah Cagil
PURPOSE: To report on a keratoconus (KC) patient with Axenfeld-Rieger syndrome (ARS) who developed sterile keratitis after accelerated corneal collagen cross-linking (CXL). METHODS: An 18-year-old patient with ARS and KC who had previously undergone intrastromal ring segment implantation underwent accelerated CXL (9 mW/cm2  UVA intensity for 10 min). RESULTS: After uneventful surgery, the patient presented with severe photophobia, redness of the eye, and decreased vision 72 h following the procedure...
March 28, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29564655/template-based-methodology-for-the-simulation-of-intracorneal-segment-ring-implantation-in-human-corneas
#2
REVIEW
Julio Flecha-Lescún, Begoña Calvo, Jesús Zurita, Miguel Ángel Ariza-Gracia
Keratoconus is an idiopathic, non-inflammatory and degenerative corneal disease characterised by a loss of the organisation in the corneal collagen fibrils. As a result, keratoconic corneas present a localised thinning and conical protrusion with irregular astigmatism and high myopia that worsen visual acuity. Intracorneal ring segments (ICRSs) are used in clinic to regularise the corneal surface and to prevent the disease from progressing. Unfortunately, the post-surgical effect of the ICRS is not explicitly accounted beforehand...
March 21, 2018: Biomechanics and Modeling in Mechanobiology
https://www.readbyqxmd.com/read/29543194/-strength-properties-of-rabbit-cornea-after-femtosecond-laser-keratoplasty-with-and-without-different-intracorneal-implants
#3
N P Pashtaev, N A Pozdeeva, V V Zotov, M V Sinitsyn, M A Shcheglova
AIM: to conduct a comparative experimental study of the effect of the use of intracorneal implants during femtosecond laser-assisted intrastromal pocket (IP) and intrastromal tunnel (IT) formation on the strength properties of the cornea. MATERIAL AND METHODS: The experimental study was performed on 24 corneas of 12 rabbit eyes enucleated 1 month after slaughtering. All eyes were divided into 6 groups according to the method of operation. IP and IT were created with IntraLase FS 60 kHz femtolaser...
2018: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/29506241/pitx2-deficiency-and-associated-human-disease-insights-from-the-zebrafish-model
#4
Kathryn E Hendee, Elena A Sorokina, Sanaa S Muheisen, Linda M Reis, Rebecca C Tyler, Vujica Markovic, Goran Cuturilo, Brian A Link, Elena V Semina
The PITX2 (paired-like homeodomain 2) gene encodes a bicoid-like homeodomain transcription factor linked with several human disorders. The main associated congenital phenotype is Axenfeld-Rieger syndrome, type 1 (ARS), an autosomal dominant condition characterized by variable defects in the anterior segment of the eye, an increased risk of glaucoma, craniofacial dysmorphism and dental and umbilical anomalies; in addition to this, one report implicated PITX2 in ring dermoid of the cornea and a few others described cardiac phenotypes...
March 1, 2018: Human Molecular Genetics
https://www.readbyqxmd.com/read/29398901/simultaneous-intratunnel-cross-linking-with-intrastromal-corneal-ring-segment-implantation-versus-simultaneous-epithelium-off-cross-linking-with-intrastromal-corneal-ring-segment-implantation-for-keratoconus-management
#5
Mohamed Hosny, Moustafa Nour, Sarah Azzam, Mohsen Salem, Esraa El-Mayah
Purpose: The purpose of this study is to compare the efficacy of intratunnel cross-linking combined with intrastromal corneal ring segment (ICRS) implantation versus combined epithelium-off (epi-off) cross-linking and ICRS implantation for the management of keratoconus. Methods: Our study included 20 eyes of 12 patients with moderate-to-severe keratoconus. Group A included 10 eyes that underwent simultaneous ICRS implantation with intratunnel cross-linking. Group B included 10 eyes that underwent simultaneous ICRS implantation with epi-off cross-linking...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29238735/post-keratoplasty-astigmatism-management-by-relaxing-incisions-a-systematic-review
#6
REVIEW
Gaëlle Ho Wang Yin, Louis Hoffart
Postoperative visual acuity can be limited by post-keratoplasty astigmatism, even with a clear corneal graft. Astigmatism management can be performed by selective suture removal, adjustment of sutures, optical correction, photorefractive procedures, wedge resection, intra-ocular lens implantation, intracorneal ring segments, relaxing incisions with or without compression sutures and repeated keratoplasty. Relaxing incisions can be made in the graft, graft-host interface or host cornea. Despite the unpredictability of the method because the flat and steep meridians are usually not orthogonal after penetrating keratoplasty, with asymmetric power distribution, all the studies showed an overall reduction of refractive, keratometric or topographic astigmatism, ranging from 30% to 72% with manual or femtosecond-assisted techniques...
2017: Eye and Vision (London, England)
https://www.readbyqxmd.com/read/29074305/scleral-lens-after-intracorneal-ring-segments-in-patients-with-keratoconus
#7
Varsha M Rathi, Preeji S Mandathara, Srikanth Dumpati, Virender S Sangwan
BACKGROUND: To report the use of scleral lens (ScCL) to improve vision in patients having keratoconus who had intracorneal ring segment (ICRS) surgery. METHODS: Two eyes of two keratoconus patients fitted with ScCL (PROSE - prosthetic replacement of the ocular surface ecosystem, USA) after having undergone ICRS surgery are reported as noncomparative interventional case series. The ICRS implanted were INTACs and kerarings. Indications, visual acuity with ScCL, complications and follow-up are reported...
October 24, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/29062770/dependence-of-dynamic-contour-and-goldmann-applanation-tonometries-on-peripheral-corneal-thickness
#8
Federico Saenz-Frances, Claudia Sanz-Pozo, Lara Borrego-Sanz, Luis Jañez, Laura Morales-Fernandez, Jose Maria Martinez-de-la-Casa, Julian Garcia-Sanchez, Julian Garcia-Feijoo, Enrique Santos-Bueso
AIM: To determine the effects of peripheral corneal thickness (PCT) on dynamic contour tonometry(DCT) and Goldmann applanation tonometry (GAT). METHODS: A cross-sectional study. We created a software which calculates the corneal contour (CC) as a function of the radius from the corneal apex to each pixel of the contour. The software generates a central circumference with a radius of 1 mm and the remainder of the cornea is segmented in 5 rings concentric with corneal apex being its diameter not constant around the corneal circumference as a consequence of the irregular CC but keeping constant the diameter of each ring in each direction of the contour...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28957978/evaluation-of-the-reliability-and-repeatability-of-scheimpflug-system-measurement-in-keratoconus
#9
Beatriz de Luis Eguileor, Julene Escudero Argaluza, Jose Ignacio Pijoán Zubizarreta, Alaitz Santamaria Carro, Jaime Etxebarria Ecenarro
PURPOSE: To assess the reliability and repeatability of the parameters obtained using a Scheimpflug system (Pentacam HR-high resolution) for monitoring progression in eyes with keratoconus. METHODS: A prospective study was conducted based on measurements taken with the Pentacam HR in 82 eyes with keratoconus. We calculated the intraclass correlation coefficient (ICC) and the repeatability limit for topographic and aberrometric parameters. RESULTS: All the parameters analyzed had excellent ICCs, above 0...
February 2018: Cornea
https://www.readbyqxmd.com/read/28932339/penetrating-keratoplasty-for-keratoconus-excimer-versus-femtosecond-laser-trephination
#10
Berthold Seitz, Achim Langenbucher, Tobias Hager, Edgar Janunts, Moatasem El-Husseiny, Nora Szentmáry
BACKGROUND: In case of keratoconus, rigid gas-permeable contact lenses as the correction method of first choice allow for a good visual acuity for quite some time. In a severe stage of the disease with major cone-shaped protrusion of the cornea, even specially designed keratoconus contact lenses are no more tolerated. In case of existing contraindications for intrastromal ring segments, corneal transplantation typically has a very good prognosis. METHODS: In case of advanced keratoconus - especially after corneal hydrops due to rupture of Descemet's membrane - penetrating keratoplasty (PKP) still is the surgical method of first choice...
2017: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/28913508/confocal-biomicroscopic-changes-of-the-corneal-layers-following-femtosecond-laser-assisted-myoring-implantation-in-keratoconus
#11
Heidar Siatiri, Mahmoud Jabbarvand, Mehrdad Mohammadpour, Amirhossein Mollazadeh, Nasim Siatiri, Arash Mirmohammadsadeghi
PURPOSE: To evaluate the effect of the femtosecond laser-assisted MyoRing implantation on the confocal biomicroscopic findings in different corneal layers of the patients with keratoconus. METHODS: Twelve eyes of 12 patients with mild to moderate keratoconus (keratometry between 48 and 52 diopters) and intolerance to hard contact lens entered the study. All the included patients underwent femtosecond laser-assisted MyoRing (Dioptex GmBH, Linz, Austria) implantation...
September 2017: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/28852910/pediatric-keratoconus-a-review-of-the-literature
#12
REVIEW
Sabrina Mukhtar, Balamurali K Ambati
PURPOSE: To describe the epidemiology and prevalence, rates of progression, difference between adult and pediatric populations, and therapeutic approaches to pediatric keratoconus from documented literature. METHODS: A literature search was done on PubMed using key words including pediatric keratoconus, children with keratoconus, adult keratoconus, penetrating keratoplasty, corneal cross-linking and intracorneal ring segments. The literature was reviewed and reported to explore the key epidemiological differences between the pediatric and adult population with regards to presentation and treatment options...
August 29, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28755306/keratoconus-treatment-algorithm
#13
REVIEW
Konstantinos D Andreanos, Kate Hashemi, Myrsini Petrelli, Konstantinos Droutsas, Ilias Georgalas, George D Kymionis
Keratoconus management has significantly changed over the last two decades. The advent of new interventions such as cornea cross-linking, intrastromal corneal ring segments, and combined treatments provide corneal clinicians a variety of treatment options for the visual rehabilitation of keratoconus patients. This review summarizes current evidence for these treatments and highlights their place in keratoconus management while new promising emerging therapies are being investigated.
December 2017: Ophthalmology and Therapy
https://www.readbyqxmd.com/read/28658437/indications-and-visual-outcomes-of-intrastromal-corneal-ring-segment-implantation-in-a-large-patient-series
#14
Taíse Tognon, Mauro Campos, João Paulo Wengrzynovski, Kleyton Arlindo Barella, Adriano Pasqualotti, Luiz Antônio de Brito Martins, Adriana Dos Santos Forseto, Luciene Barbosa de Sousa
OBJECTIVES: To describe the indications for and visual outcomes of intrastromal corneal ring segment implantation. METHODS: A large retrospective case-series chart-review study was conducted using Sorocaba Ophthalmological Hospital medical records. This study included 1222 eyes (1196 patients) that were surgically treated between November 2009 and December 2012. The following preoperative data were collected: age, gender, type of medical care and funding source, surgical technique, best-corrected visual acuity, manifest sphere and cylinder refractive error, maximum and minimum central keratometry, and pachymetry measurements of the cornea at the thinnest point and at the ring channel...
June 2017: Clinics
https://www.readbyqxmd.com/read/28632845/iris-malformation-and-anterior-segment-dysgenesis-in-mice-and-humans-with-a-mutation-in-pi-3-kinase
#15
Marie H Solheim, Allen C Clermont, Jonathon N Winnay, Erlend Hallstensen, Anders Molven, Pål R Njølstad, Eyvind Rødahl, C Ronald Kahn
Purpose: To determine the ocular consequences of a dominant-negative mutation in the p85α subunit of phosphatidylinositol 3-kinase (PIK3R1) using a knock-in mouse model of SHORT syndrome, a syndrome associated with short stature, lipodystrophy, diabetes, and Rieger anomaly in humans. Methods: We investigated knock-in mice heterozygous for the SHORT syndrome mutation changing arginine 649 to tryptophan in p85α (PIK3R1) using physical examination, optical coherence tomography (OCT), tonometry, and histopathologic sections from paraffin-embedded eyes, and compared the findings to similar investigations in two human subjects with SHORT syndrome heterozygous for the same mutation...
June 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28573989/evaluation-of-kayser-fleischer-ring-in-wilson-disease-by-anterior-segment-optical-coherence-tomography
#16
Mittanamalli S Sridhar, Advithi Rangaraju, Kavitha Anbarasu, Sharat Putta Reddy, Sachin Daga, Sita Jayalakshmi, Bajibhi Shaik
PURPOSE: The purpose of the study is to present anterior segment optical coherence tomography (AS-OCT) as an alternative method of evaluating Kayser-Fleischer (KF) ring in Wilson disease (WD) not only by ophthalmologists but also by other clinicians dealing with WD. MATERIALS AND METHODS: This was a retrospective case series of six WD patients with KF ring. Evaluation of KF ring was done by naked eye examination using torch light, slit lamp biomicroscopy (SL), and AS-OCT...
May 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28476917/optical-coherence-tomography-of-the-kayser-fleischer-ring-an-ancillary-diagnostic-tool-for-wilson-s-disease-in-children
#17
Anubha Rathi, Brijesh Takkar, Nripen Gaur, Prafulla Kumar Maharana
This report presents anterior segment optical coherence tomography (AS-OCT) images of Kayser-Fleischer ring (KFR) in a child. The AS-OCT images highlight differential reflectivity of the KFR depending on amount of copper deposited in cornea, thus supporting the role of AS-OCT as a follow-up tool. Utility of AS-OCT for diagnosing and documenting the KFR in children otherwise uncooperative for detailed slit lamp examination is discussed.
May 5, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28393023/mathematical-analysis-of-corneal-remodelling-after-intracorneal-ring-surgery-in-keratoconus
#18
Elias F Jarade, Elise Slim, Carole Cherfan, Hala El Rami, Toufic Hassan, Elias Chelala
AIM: To represent mathematically the intersection between the ectatic corneal geometry and the plane of intracorneal ring implants (ICRS) in order to determine the corneal response to ICRS surgery in keratoconus (KC). Thereafter, to present the concept and early results of a newly derived topography-guided nomogram for ICRS surgery for the treatment of keratectasia. METHODS: The corneal rings plane intersection was modelled to a conic section. Ring effect was the result of: the ring size, position (steep vs flat), location (distance from the geometric centre of the cornea), and the discrepancy between the ring's curvature and the tunnel's curvature...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28358216/evaluation-of-the-safety-and-tolerability-of-conjunctival-ring-for-posterior-segment-of-the-eye
#19
Satoshi Kinoshita, Takeshi Ohguchi, Kousuke Noda, Miyuki Murata, Shin-Ichi Yasueda, Haruka Obata, Toru Matsunaga, Tsutomu Fukushima, Atsuhiro Kanda, Susumu Ishida
PURPOSE: To evaluate the safety and tolerability of conjunctival rings (CRs), a novel device for drug delivery to the posterior segment of the eye. METHODS: In animal studies, CRs containing 5% dexamethasone sodium phosphate (DSP) or vehicle solution were placed on the right and left eyes of C57BL/6J mice, respectively. Contact lenses (CLs) containing vehicle solution were used as a control. Twenty-four hours after placement of the CRs, corneal fluorescein staining was graded based on the McDonald-Shadduck scoring system, ranging from 0 to 4...
August 2017: Current Eye Research
https://www.readbyqxmd.com/read/28341606/safety-and-efficacy-of-sequential-intracorneal-ring-segment-implantation-and-cross-linking-in-pediatric-keratoconus
#20
Youssef Abdelmassih, Sylvain El-Khoury, Ali Dirani, Rafic Antonios, Ali Fadlallah, Carole G Cherfan, Elias Chelala, Elias F Jarade
PURPOSE: To evaluate the safety and visual outcome of intracorneal ring segment (ICRS) implantation followed by cross-linking in pediatric keratoconus patients. DESIGN: Retrospective interventional case series. METHODS: This retrospective study included pediatric patients (aged ≤14 years) with keratoconus and poor corrected distance visual acuity (CDVA) that underwent ICRS implantation and cross-linking (CXL). ICRS were inserted under topical anesthesia after creating a corneal tunnel with a femtosecond laser...
June 2017: American Journal of Ophthalmology
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