Marius-Cosmin Colceriu, Paul Luchian Aldea, Andreea-Liana Boț Răchişan, Bogdan Bulată, Dan Delean, Alina Grama, Alexandra Mititelu, Roxana Maria Decea, Alexandra Sevastre-Berghian, Simona Clichici, Tudor Lucian Pop, Teodora Mocan
Vesicoureteral reflux (VUR) is one of the most important disorders encountered in pediatric nephrology due to its frequency and potential evolution to chronic kidney disease (CKD). The aim of our study was to identify noninvasive and easy-to-determine urinary markers to facilitate the diagnosis and staging of VUR. We performed a cross-section study including 39 patients with VUR followed over three years (August 2021-September 2023) and 39 children without urinary disorder (the control group). We measured the urinary concentration of interleukin-6 (IL-6), cathelicidin (LL-37), and neutrophil gelatinase-associated lipocalin (NGAL) in VUR and healthy controls...
December 17, 2023: International Journal of Molecular Sciences