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Portal vein thrombosis

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https://www.readbyqxmd.com/read/29792748/portal-vein-thrombosis-imaging-the-spectrum-of-disease-with-an-emphasis-on-mri-features
#1
Reena C Jha, Satinderpal Singh Khera, Amit Dinesh Kalaria
OBJECTIVE: The purpose of this article is to review the classic and uncommon imaging findings of portal vein thrombosis (PVT) (acute, chronic, congenital, and septic thrombus) as visualized on multiple modalities, with an emphasis on MRI findings. Additional aims are to understand the imaging of obliterative portal venopathy and its clinical significance, appreciate morphologic changes of the biliary system that may accompany PVT, and recognize changes in liver enhancement patterns seen with PVT related to the hepatic arterial buffer response...
May 24, 2018: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29790286/vascular-reconstruction-technique-of-a-perforated-portal-vein-during-a-pediatric-total-pancreatectomy-and-islet-autotransplant
#2
Kent J Peterson, Oscar K Serrano, Siobhan Flanagan, Srinath Chinnakotla
Hereditary pancreatitis (HP) is a progressive disease that can manifest in childhood with debilitating, relapsing pain. A total pancreatectomy and islet autotransplant (TPIAT) is a surgical option to relieve chronic pain while preserving the available beta-cell mass. The clinical course of HP is fraught with pancreatitis-related sequelae that can both necessitate and complicate a TPIAT. We describe a child with HP who developed a pancreatic pseudocyst-portal vein (PV) fistula. Active hemorrhage of the perforated PV into the pseudocyst and PV thrombosis complicated the planned TPIAT procedure and, preoperatively, required urgent image-guided stenting...
May 22, 2018: American Journal of Transplantation
https://www.readbyqxmd.com/read/29786890/thrombotic-and-hemorrhagic-complications-during-visceral-transplantation-risk-factors-and-association-with-intraoperative-disseminated-intravascular-coagulation-like-thromboelastographic-qualities-single-center-retrospective-study
#3
Yehuda Raveh, Yiliam Rodriguez, Ernesto Pretto, Fouad Souki, Vadim Shatz, Behrouz Ashrafi, Vinaya Manmohansigh, Michael Demos, Joshua Livingstone, Georges Nasrallah, David Andrews, Thiago Beduschi, Rodrigo Vianna, Ramona Nicolau-Raducu
This study describes the risk of thrombotic and hemorrhagic complications, both intraoperatively, and up to 1-month following visceral transplantation. Data from 48 adult visceral transplants performed between 2010-2017 were retrospectively studied (32 multivisceral (MVTx); 10 isolated intestine; 6 modified-MVTx). Intraoperatively, intracardiac thrombosis (ICT)/pulmonary embolism (PE) occurred in 25%, 0% and 0% of MVTx, isolated intestine and modified MVTx, respectively, and was associated with 50% (4/8) mortality...
May 22, 2018: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/29766730/-splanchnic-vein-thrombosis
#4
Sylva Lajzová, Radek Kroupa, Alena Buliková, Šárka Bohatá, Barbora Packová, Michal Šenkyřík
Splanchnic vein thrombosis (SVT) represents an unusual manifestation of venous thromboembolism. The etiological factors for SVT can be divided into local and systemic, frequently found concurrently. SVT can be the first presenting symptom in myeloproliferative neoplasms. SVT puts the patients affected in jeopardy of developing the intestinal infarction, impairing the liver function and portal hypertension development with the risk of potentially life-threatening gastrointestinal bleeding. The current guidelines emphasise the role of anticoagulation in acute splanchnic thrombosis...
2018: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/29763951/dynamic-4d-ct-angiography-for-guiding-transarterial-chemoembolization-impact-on-the-reduction-of-contrast-material-operator-radiation-exposure-catheter-consumption-and-diagnostic-confidence
#5
Moritz H Albrecht, Thomas J Vogl, Julian L Wichmann, Simon S Martin, Jan-Erik Scholtz, Sebastian Fischer, Renate M Hammerstingl, Marc Harth, Nour-Eldin A Nour-Eldin, Axel Thalhammer, Stephan Zangos, Ralf W Bauer
PURPOSE:  This study was carried out to investigate the impact of abdominal dynamic four-dimensional CT angiography (4D-CTA) for guiding transarterial chemoembolization (TACE) on the amount of contrast material used, operator radiation exposure, catheter consumption, and diagnostic confidence. MATERIALS AND METHODS:  Written consent was waived for this IRB-approved retrospective study. 29 patients (20 men; mean age: 65.7 ± 11.5 years) with malignant liver lesions underwent 4D-CTA, prior to initial TACE...
June 2018: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
https://www.readbyqxmd.com/read/29756168/transsplenic-splenoportography-and-portal-venous-interventions-in-pediatric-patients
#6
Eric J Monroe, Ethan J Speir, C Matthew Hawkins, Giri Shivaram, Kevin S H Koo, Anne E Gill
BACKGROUND: Data regarding transsplenic portal venous access for diagnostic imaging and endovascular intervention in children are limited, possibly due to concerns regarding high bleeding risks and resultant underutilization. OBJECTIVE: To investigate the safety and utility of transsplenic splenoportography and portal venous interventions in children. MATERIALS AND METHODS: A retrospective review was performed of all pediatric patients undergoing percutaneous transsplenic portal venous access and intervention at two large tertiary pediatric institutions between January 2012 and April 2017 was performed...
May 13, 2018: Pediatric Radiology
https://www.readbyqxmd.com/read/29751198/price-to-pay-portal-vein-arterialization-for-hepatic-artery-thrombosis-after-living-donor-liver-transplantation-a-case-report
#7
Worakitti Lapisatepun, Anon Chotirosniramit, Trichak Sandhu, Kanya Udomsin, Wasana Ko-Iam, Phuriphong Chanthima, Warangkana Lapisatepun, Settapong Boonsri, Suraphong Lorsomradee, Quanhathai Kaewpoowat, Sunhawit Junrungsee
OBJECTIVE: Hepatic artery thrombosis (HAT) is one of the most serious complications of liver transplantation that can potentially lead to loss of the allograft. Retransplantation is the only option when revascularization can't be performed but the donor may be not available in the short period of time. We report the technique of using portal vein arterialization (PVA) for bridging before retransplantation. There are few reports in living donor setting. CASE DESCRIPTION: The recipient of the liver was a 59 year old male who received an extended right lobe graft from his son...
May 2, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29747524/congenital-thrombophilia-in-patients-with-superior-mesenteric-venous-thrombosis-or-portal-vein-thrombosis
#8
Ikejiri Makoto, Masanobu Usui, Hideo Wada, Takeshi Matsumoto, Kohshi Ohishi, Akihiro Shindo, Yoshiki Yamashita, Kaname Nakatani, Shigehisa Tamaki, Hidekazu Tomimoto, Shuji Isaji
We explored the relationship between abdominal vein thromboses, including portal vein thrombosis (PVT) and superior mesenteric vein thrombosis (SMVT), and thrombophilia. The frequency of thrombophilia, such as antithrombin (AT), protein C (PC), or protein S (PS) gene mutations, was examined in 21 patients with PVT, 6 patients with SMVT, and 6 patients with both PVT and SMVT. Low levels of AT, PC, or PS were frequently detected in patients with PVT or mesenteric vein thrombosis, and 4 mutations in the PS gene, 3 mutations in the PC gene, and 2 mutations in AT the gene were detected...
January 1, 2018: Clinical and Applied Thrombosis/hemostasis
https://www.readbyqxmd.com/read/29745475/metabolic-disorders-across-hepatocellular-carcinoma-in-italy
#9
Filomena Morisco, Maria Guarino, Maria Rosa Valvano, Francesco Auriemma, Fabio Farinati, Edoardo G Giannini, Francesca Ciccarese, Francesco Tovoli, Gian Ludovico Rapaccini, Maria Di Marco, Eugenio Caturelli, Marco Zoli, Franco Borzio, Rodolfo Sacco, Giuseppe Cabibbo, Martina Felder, Luisa Benvengù, Antonio Gasbarrini, Gianluca Svegliati Baroni, Francesco Giuseppe Foschi, Elisabetta Biasini, Alberto Masotto, Roberto Virdone, Fabio Marra, Nicola Caporaso, Franco Trevisani
BACKGROUND: Metabolic disorders are well known risk factors for HCC. Conversely, their impact on the natural history of HCC is not established. This study aimed at evaluating the impact of metabolic disorders on clinical features, treatment and survival of HCC patients regardless of its etiology. METHODS: We analyzed the ITA.LI.CA database regarding 839 HCC patients prospectively collected. The following metabolic features were analyzed: BMI, diabetes, arterial hypertension, hypercholesterolemia and hypertriglyceridemia...
May 10, 2018: Liver International: Official Journal of the International Association for the Study of the Liver
https://www.readbyqxmd.com/read/29735798/thrombosis-of-the-portal-venous-system-in-cirrhotic-vs-non-cirrhotic-patients
#10
Vania Cruz-Ramón, Paulina Chinchilla-López, Oscar Ramírez-Pérez, Nancy E Aguilar-Olivos, Luis F Alva-López, Ericka Fajardo-Ordoñez, Ileana Acevedo-Silva, Patrick G Northup, Nicolas Intagliata, Stephen H Caldwell, Guadalupe Ponciano-Rodríguez, Xingshun Qi, Nahum Méndez-Sánchez
INTRODUCTION AND AIM: Thrombosis is a vascular disorder of the liver often associated with significant morbidity and mortality. Cirrhosis is a predisposing factor for portal venous system thrombosis. The aim of this study is to determine differences between cirrhotics and non-cirrhotics that develop thrombosis in portal venous system and to evaluate if cirrhosis severity is related to the development of portal venous system thrombosis. MATERIAL AND METHODS: We studied patients diagnosed with portal venous system thrombosis using contrast-enhanced computed tomography scan and doppler ultrasound at Medica Sur Hospital from 2012 to 2017...
April 9, 2018: Annals of Hepatology
https://www.readbyqxmd.com/read/29723419/vein-resection-during-pancreaticoduodenectomy-for-pancreatic-adenocarcinoma-patency-rates-and-outcomes-associated-with-thrombosis
#11
Rebecca A Snyder, Laura R Prakash, Graciela M Nogueras-Gonzalez, Michael P Kim, Thomas A Aloia, Jean-Nicolas Vauthey, Jeffrey E Lee, Jason B Fleming, Matthew H G Katz, Ching-Wei D Tzeng
BACKGROUND AND OBJECTIVES: Venous patency rates after pancreaticoduodenectomy (PD) with portal vein (PV) resection are not well established, and the oncologic impact of portal vein thrombosis (PVT) is unknown. The primary aim of this study was to determine rates and predictors of PVT after PD with PV resection for pancreatic adenocarcinoma (PDAC). METHODS: A retrospective cohort study was performed on PDAC patients treated with preoperative therapy and PD with PV resection at a high-volume institution (2008-15)...
May 3, 2018: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29720864/role-of-thrombophilia-in-splanchnic-venous-thrombosis-in-acute-pancreatitis
#12
Sobur Uddin Ahmed, Surinder S Rana, Jasmina Ahluwalia, Neelam Varma, Ravi Sharma, Rajesh Gupta, Mandeep Kang
Background: Splanchnic venous thrombosis (SVT) is a common vascular complication of acute pancreatitis (AP). We conducted this study to prospectively investigate the frequency, risk factors, and extent of SVT in patients with AP and to evaluate the role of thrombophilia in its causation. Methods: Patients with AP presenting between January 2015 and June 2016 were prospectively evaluated with contrast-enhanced computed tomography (CT) for the presence of SVT. These patients underwent a detailed analysis of coagulation parameters...
May 2018: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
https://www.readbyqxmd.com/read/29720857/portal-vein-thrombosis-in-cirrhosis-diagnosis-natural-history-and-therapeutic-challenges
#13
REVIEW
Aikaterini Mantaka, Aikaterini Augoustaki, Elias A Kouroumalis, Dimitrios N Samonakis
Portal vein thrombosis (PVT) is a frequent complication in cirrhosis and its prevalence increases with disease severity. Several factors are involved in the development and progression of PVT. The challenge for the management of PVT is the precise evaluation of the bleeding risk as opposed to life-threatening extension of thrombosis. Nevertheless, the impact on the progression and outcome of liver disease is unclear. A critical evaluation of the available data discloses that treating PVT in cirrhotics is safe and effective...
May 2018: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
https://www.readbyqxmd.com/read/29718791/radioembolization-in-advanced-hepatocellular-carcinoma
#14
Ahsun Riaz, Robert Lewandowski, Riad Salem
The Oncology Grand Rounds series is designed to place original reports published in the Journal into clinical context. A case presentation is followed by a description of diagnostic and management challenges, a review of the relevant literature, and a summary of the authors' suggested management approaches. The goal of this series is to help readers better understand how to apply the results of key studies, including those published in Journal of Clinical Oncology, to patients seen in their own clinical practice...
May 2, 2018: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/29709665/symptomatic-venous-thromboembolism-is-associated-with-inferior-survival-among-patients-undergoing-nephrectomy-with-inferior-vena-cava-tumor-thrombectomy-for-renal-cell-carcinoma
#15
Paras H Shah, R Houston Thompson, Stephen A Boorjian, Christine M Lohse, Timothy D Lyon, Raymond C Shields, David Froehling, Bradley C Leibovich, Boyd R Viers
PURPOSE: To investigate the incidence and survival impact of symptomatic venous thromboembolism after nephrectomy with inferior vena cava tumor thrombectomy. METHODS: A retrospective review was performed of 183 patients undergoing nephrectomy with inferior vena cava tumor thrombectomy (Level I-IV) between 2000 and 2010 for renal cell carcinoma. Postoperative venous thromboembolism was defined as symptomatic bland thrombus or embolism confirmed with imaging. Cumulative incidence of venous thromboembolism was estimated using the Kaplan-Meier method...
April 27, 2018: Journal of Urology
https://www.readbyqxmd.com/read/29707074/hepatobiliary-manifestations-and-complications-in-inflammatory-bowel-disease-a-review
#16
REVIEW
Fotios S Fousekis, Vasileios I Theopistos, Konstantinos H Katsanos, Epameinondas V Tsianos, Dimitrios K Christodoulou
Liver and biliary track diseases are common extraintestinal manifestations of inflammatory bowel disease (IBD), reported both in Crohn's disease and ulcerative colitis, and may occur at any time during the natural course of the disease. Their etiology is mainly related to pathophysiological changes induced by IBD, and secondary, due to drugs used in IBD. Fatty liver is considered as the most frequent hepatobiliary manifestation in IBD, while primary sclerosing cholangitis (PSC) is the most correlated hepatobiliary disorder and is more prevalent in patients with ulcerative colitis...
April 2018: Gastroenterology Research
https://www.readbyqxmd.com/read/29704104/total-endovascular-iliocaval-reconstruction-using-polytetrafluoroethylene-stent-graft-placement-for-the-treatment-of-inferior-vena-cava-resection
#17
Kyle J Cooper, Jeffrey Forris Beecham Chick, Minhaj S Khaja, Ravi N Srinivasa, Jordan Fenlon, Charles Brewerton, David M Williams
Resection of the inferior vena cava (IVC) is a rare surgical technique that is occasionally combined with nephrectomy in the setting of renal malignancy with intravascular tumor extension. While this may be fairly well tolerated in some patients due to extensive collateralization in the venous system, there is a clear potential for lower extremity venous insufficiency and deep vein thrombosis (DVT). This report describes a patient who underwent right nephrectomy and segmental IVC resection from the subhepatic space to the iliac confluence, which was complicated by profoundly symptomatic lower extremity DVT and gastrointestinal hemorrhage due to system-to-portal shunting...
April 27, 2018: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/29692535/t-pa-power-pulse-spray-with-rheolytic-mechanical-thrombectomy-using-cross-sectional-image-guided-portal-vein-access-for-single-setting-treatment-of-subacute-superior-mesenteric-vein-thrombosis
#18
Mubin I Syed, Ryan M Gallagher, Rukan S Ahmed, Azim Shaikh, Edward Roberto, Sumeet Patel
Background: Isolated superior mesenteric vein (SMV) thrombosis is a rare but potentially fatal condition if untreated. Current treatments include transjugular or transhepatic approaches for rheolytic mechanical thrombectomy and subsequent infusions of thrombolytics. Tissue plasminogen activator (t-PA) power-pulse spray can provide benefit in a single setting without thrombolytic infusions. Computed tomography (CT) guidance for portal vein access is underutilized in this setting. Materials and Methods: Case 1 discusses acute SMV thrombosis treated with rheolytic mechanical thrombectomy alone using ultrasound guidance for portal vein access...
January 2018: Indian Journal of Radiology & Imaging
https://www.readbyqxmd.com/read/29692529/portal-vein-thrombosis-after-donor-liver-biopsy-case-report
#19
Shahnawaz Bashir, Kartik Mittal, Rohit Khisti, Ankusha Yadav, Amar Mukund, Viniyendra Pamecha
Percutaneous plugged liver biopsy is a safe procedure with a low complication rate. Portal vein thrombosis has not been reported after percutaneous liver biopsy in the literature. We present a case of portal vein thrombosis after percutaneous plugged liver biopsy in a voluntary liver donor, which was subsequently treated with catheter-directed percutaneous transhepatic thrombolysis. In future, healthy patients undergoing liver biopsies are expected to increase for donor evaluation. More refinements of technique and hardware in the future may further decrease the rate of complications...
January 2018: Indian Journal of Radiology & Imaging
https://www.readbyqxmd.com/read/29686471/analysis-of-aggressiveness-factors-in-hepatocellular-carcinoma-patients-undergoing-transarterial-chemoembolization
#20
Yossi Ventura, Brian I Carr, Issac Kori, Vito Guerra, Oren Shibolet
AIM: To investigate novel predictors of survival in hepatocellular carcinoma (HCC) patients following transarterial chemoembolization (TACE). METHODS: One hundred sixty seven patients with un-resectable HCC were retrospectively analyzed to identify factors that might contribute to their HCC biology and aggressiveness. We correlated routine laboratory results (total bilirubin, AST, ALKP, GGTP, albumin etc .) to maximum tumor diameter, number of tumor nodules, portal vein thrombosis and blood alpha-fetoprotein levels...
April 21, 2018: World Journal of Gastroenterology: WJG
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