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https://www.readbyqxmd.com/read/28430884/a-20-year-temporal-change-analysis-in-incidence-presenting-phenotype-and-mortality-in-the-dutch-ibdsl-cohort-can-diagnostic-factors-explain-the-increase-in-ibd-incidence
#1
Tim R A van den Heuvel, Steven F G Jeuring, Maurice P Zeegers, Dorien H E van Dongen, Anouk Wolters, Ad A M Masclee, Wim H Hameeteman, Marielle J L Romberg-Camps, Liekele E Oostenbrug, Marieke J Pierik, Daisy M Jonkers
Background: The aim was to study temporal changes in incidence, disease phenotype at diagnosis, and mortality of adult inflammatory bowel disease (IBD) patients in South Limburg, the Netherlands, diagnosed between 1991 and 2010. In addition, the 2010 IBD prevalence was estimated. Methods: A multi-faceted approach including hospital administrations, the national pathology registry, and general practitioners led to the identification of 1162 patients with Crohn's disease (CD), 1663 with ulcerative colitis (UC) and 84 with unclassified IBD (IBD-U)...
April 20, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28430518/tunable-sign-change-of-spin-hall-magnetoresistance-in-pt-nio-yig-structures
#2
Dazhi Hou, Zhiyong Qiu, Joseph Barker, Koji Sato, Kei Yamamoto, Saül Vélez, Juan M Gomez-Perez, Luis E Hueso, Fèlix Casanova, Eiji Saitoh
Spin Hall magnetoresistance (SMR) has been investigated in Pt/NiO/YIG structures in a wide range of temperature and NiO thickness. The SMR shows a negative sign below a temperature that increases with the NiO thickness. This is contrary to a conventional SMR theory picture applied to the Pt/YIG bilayer, which always predicts a positive SMR. The negative SMR is found to persist even when NiO blocks the spin transmission between Pt and YIG, indicating it is governed by the spin current response of the NiO layer...
April 7, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28422922/the-spatial-epidemiology-of-pediatric-trauma-a-statewide-assessment
#3
Allison Ertl, Kirsten Beyer, Sergey Tarima, Yuhong Zhou, Jonathan I Groner, Laura D Cassidy
INTRODUCTION: Despite significant advances in the prevention and treatment of pediatric trauma, preventable injuries continue to burden the lives of millions of children. In order to target prevention strategies, it is critical to identify areas with high burdens of pediatric trauma. Therefore, this study analyzed statewide data from the Ohio Trauma Registry (OTR) from 2007-2012 to identify geographical patterns in pediatric injury. METHODS: Data from the first hospital of care for 16,330 pediatric trauma patients under 16 years old were analyzed using the disease mapping method adaptive spatial filtering to estimate a series of maps that display age- and sex-adjusted rates of pediatric trauma, severe trauma, and standardized mortality ratios (SMR) while controlling for population size to create stable estimates throughout the study area...
April 18, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28419542/effect-of-nanosilver-on-metabolism-in-rainbow-trout-oncorhynchus-mykiss-an-investigation-using-different-respirometric-approaches
#4
Laura Murray, Michael D Rennie, Jon C Svendsen, Eva C Enders
Nanosilver (nAg) has been incorporated into many consumer products for its antimicrobial properties, including clothing and washing machines. Consequently, the potential for its release into aquatic environments is of significant concern. Documented toxic effects on fish include altered gene expression, gill damage, impaired gas exchange, as well as mortality at high nAg concentrations. This study reports the effects of nAg on the metabolism of Rainbow Trout (Oncorhynchus mykiss). Fish were exposed to environmentally-relevant concentrations (0...
April 17, 2017: Environmental Toxicology and Chemistry
https://www.readbyqxmd.com/read/28417839/mortality-due-to-cardiovascular-disease-among-apollo-lunar-astronauts
#5
Robert J Reynolds, Steven M Day
INTRODUCTION: Recent research has postulated increased cardiovascular mortality for astronauts who participated in the Apollo lunar missions. The conclusions, however, are based on small numbers of astronauts, are derived from methods with known weaknesses, and are not consistent with prior research. METHODS: Records for NASA astronauts and U.S. Air Force astronauts were analyzed to produce standardized mortality ratios. Lunar astronauts were compared to astronauts who have never flown in space (nonflight astronauts), those who have only flown missions in low Earth orbit (LEO astronauts), and the U...
May 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28416956/mutations-in-streptomycin-resistance-genes-and-their-relationship-to-streptomycin-resistance-and-lineage-of-mycobacterium-tuberculosis-thai-isolates
#6
Yin Moe Hlaing, Pongsri Tongtawe, Pramuan Tapchaisri, Jeeraphong Thanongsaksrikul, Unchana Thawornwan, Buppa Archanachan, Potjanee Srimanote
BACKGROUND: Streptomycin (SM) is recommended by the World Health Organization (WHO) as a part of standard regimens for retreating multidrug-resistant tuberculosis (MDR-TB) cases. The incidence of MDR-TB in retreatment cases was 19% in Thailand. To date, information on SM resistance (SMR) gene mutations correlated to the SMR of Mycobacterium tuberculosis Thai isolates is limited. In this study, the mutations in rpsL, rrs, gidB, and whiB7 were investigated and their association to SMR and the lineage of M...
April 2017: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28414714/excess-atherosclerosis-in-systemic-lupus-erythematosus-a-matter-of-renal-involvement-case-control-study-of-281-sle-patients-and-281-individually-matched-population-controls
#7
Johanna T Gustafsson, Marie Herlitz Lindberg, Iva Gunnarsson, Susanne Pettersson, Kerstin Elvin, John Öhrvik, Anders Larsson, Kerstin Jensen-Urstad, Elisabet Svenungsson
BACKGROUND: Systemic lupus erythematosus (SLE), is a heterogeneous disease which predominantly affects young females (90%). SLE is associated with a shorter life expectancy than in the general population. Standardized mortality ratios (SMR) of 2.4 have been reported, which is comparable to diabetes. In modern societies cardiovascular disease (CVD) is the major cause of premature mortality. Accelerated atherosclerosis is generally assumed to be the underlying cause for SLE related CVD...
2017: PloS One
https://www.readbyqxmd.com/read/28408992/the-risk-of-oesophageal-adenocarcinoma-in-a-prospectively-recruited-barrett-s-oesophagus-cohort
#8
B T Theron, H Padmanabhan, H Aladin, P Smith, E Campbell, P Nightingale, B T Cooper, N J Trudgill
BACKGROUND: Varying rates of oesophageal adenocarcinoma (OAC) complicating Barrett's oesophagus (BO) have been reported. Recent studies and meta-analyses suggest a lower incidence, questioning the value of endoscopic surveillance. AIM: We aimed to retrospectively examine the rate of OAC, risk factors and causes of death in a prospectively recruited BO cohort. METHODS: Data from patients with BO from a cohort from 1982-2007 were studied. Patients were subdivided into surveyed, failed to attend surveillance and unfit for surveillance...
December 2016: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/28408042/towards-the-determination-of-sulfonamides-in-meat-samples-a-magnetic-and-mesoporous-metal-organic-framework-as-an-efficient-sorbent-for-magnetic-solid-phase-extraction-combined-with-high-performance-liquid-chromatography
#9
Lian Xia, Lijie Liu, Xiaoxia Lv, Fei Qu, Guoliang Li, Jinmao You
A magnetic, mesoporous core/shell structured Fe3O4@JUC-48 nanocomposite was synthesized and employed as a magnetic solid phase extraction (MSPE) sorbent for the determination of trace sulfonamides (SAs) in meat samples. The synthesized nanocomposite was characterized by X-ray diffraction, Fourier transform infrared spectra, transmission electron microscopy, scanning electron microscopy, Brunner-Emmet-Teller, and vibrating sample magnetometry; the Fe3O4@JUC-48 nanocomposite exhibited a distinctive morphology, large surface area, high magnetism, open adsorption sites, and high chemical stability...
April 4, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28406044/stage-specific-mortality-and-survival-trends-of-prostate-cancer-patients-in-finland-before-and-after-introduction-of-psa
#10
Heikki A Seikkula, Antti J Kaipia, Matti E Rantanen, Janne M Pitkäniemi, Nea K Malila, Peter J Boström
BACKGROUND: The early diagnosis and right treatment strategy of localized prostate cancer (PCa) remains problematic. In order to characterize the survival of PCa patients, we compared patients' all-cause and cancer-specific mortalities between pre- and post-PSA periods by stage in Finland. MATERIAL AND METHODS: All PCa cases diagnosed in Finland between 1985 and 2013 (N = 91,329) were identified from the Finnish Cancer Registry (FCR). PCa stage at diagnosis was defined as localized, local node positive or metastasized...
February 13, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28388524/a-sensitive-method-for-the-determination-of-sulfonamides-in-seawater-samples-by-solid-phase-extraction-and-uv-visible-spectrophotometry
#11
Sophia Ait Errayess, Abdellatif Ait Lahcen, Laila Idrissi, Caterina Marcoaldi, Salvatore Chiavarini, Aziz Amine
The authors have developed a sensitive spectrophotometric method for determination of sulfonamide derivatives such as sulfanilamide (SAA), sulfadiazine (SDZ), sulfacetamide (SCT) sulfamethoxazole (SMX), sulfamerazine (SMR), sulfadimethoxine (SDX), sulfamethiazole (SMT) and Sulfathiazole (STZ). This method is based on the Bratton-Marshall reaction, which involves the diazotization of sulfonamides with sodium nitrite under acidic conditions, followed by coupling with N-(1-naphtyl) ethylenediamine dihydrochloride (NED) to form a pink colored compound...
March 28, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28381601/a-novel-multiplex-pcr-assay-for-the-detection-of-chlorhexidine-quaternary-ammonium-mupirocin-and-methicillin-resistance-genes-with-simultaneous-discrimination-of-staphylococcus-aureus-from-coagulase-negative-staphylococci
#12
Jo-Ann McClure, Johanna Zaal DeLongchamp, John M Conly, Kunyan Zhang
Methicillin-resistant Staphylococcus aureus (MRSA) is a clinically significant pathogen resistant to a wide variety of antibiotics and responsible for a large number of nosocomial infections worldwide. The Agency for Healthcare Research and Quality and the Centers for Disease Control and Prevention recently recommended to adopt universal mupirocin/chlorhexidine decolonization of all admitted intensive care unit patients, rather than MRSA screening with targeted treatments, which raises the serious concern about the selection of resistance to mupirocin and chlorhexidine in strains of staphylococci...
April 5, 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28378559/mortality-in-schizophrenia-and-other-psychoses-data-from-the-south-korea-national-health-insurance-cohort-2002-2013
#13
Woorim Kim, Suk Yong Jang, Sung Youn Chun, Tae Hoon Lee, Kyu Tae Han, Eun Cheol Park
Individuals with psychoses show excess mortality, which is a major public health concern. This study examined all-cause and suicide mortality rates in Korean patients diagnosed with schizophrenia, mood disorder, or mental and behavioral disorder due to psychoactive substance use and to compare this with that of the general population. Data were from the National Health Insurance cohort, 2002 to 2013. A total of 107,190 cases aged 15 years or over were included. Mortality rates per 100,000 person years (PY) were obtained...
May 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28375889/the-main-cause-of-death-following-primary-total-hip-and-knee-replacement-for-osteoarthritis-a-cohort-study-of-26-766-deaths-following-332-734-hip-replacements-and-29-802-deaths-following-384-291-knee-replacements
#14
Linda P Hunt, Yoav Ben-Shlomo, Michael R Whitehouse, Martyn L Porter, Ashley W Blom
BACKGROUND: Patients undergoing primary total joint replacement are selected for surgery and thus (other than having a transiently increased mortality rate postoperatively) have a lower mortality rate than age and sex-matched individuals do. Understanding the causes of death following joint replacement would allow targeted strategies to reduce the risk of death and optimize outcome. We aimed to determine the rates and causes of mortality for patients undergoing primary total hip or knee replacement compared with individuals in the general population who were matched for age and sex...
April 5, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28375855/cause-specific-mortality-in-a-population-based-cohort-of-9799-women-treated-for-ductal-carcinoma-in-situ
#15
Lotte E Elshof, Marjanka K Schmidt, Emiel J Th Rutgers, Flora E van Leeuwen, Jelle Wesseling, Michael Schaapveld
OBJECTIVE: To assess cause-specific mortality in women treated for ductal carcinoma in situ (DCIS). BACKGROUND: From screening and treatment perspective, it is relevant to weigh the low breast cancer mortality after DCIS against mortality from other causes and expected mortality in the general population. METHODS: We conducted a population-based cohort study comprising 9799 Dutch women treated for primary DCIS between 1989 and 2004 and estimated standardized mortality ratios (SMRs)...
April 3, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28374472/a-prospective-outcome-study-observing-patients-with-severe-traumatic-brain-injury-over-10-15%C3%A2-years
#16
E Andersson, D Rackauskaite, E Svanborg, L Csajbók, M Öst, B Nellgård
BACKGROUND: Severe traumatic brain injury (sTBI) can be divided into primary and secondary injuries. Intensive care protocols focus on preventing secondary injuries. This prospective cohort study was initiated to investigate outcome, including mortality, in patients treated according to the Lund Concept after a sTBI covering 10-15 years post-trauma. METHODS: Patients were included during 2000-2004 when admitted to the neurointensive care unit, Sahlgrenska University Hospital...
May 2017: Acta Anaesthesiologica Scandinavica
https://www.readbyqxmd.com/read/28365589/survival-and-cause-of-death-in-multiple-sclerosis-a-60-year-longitudinal-population-study
#17
Hanne-Marie Bøe Lunde, Jørg Assmus, Myhr Kjell-Morten, Lars Bø, Nina Grytten
OBJECTIVE: Survival and causes of death (COD) in multiple sclerosis (MS) provide ultimate endpoints. We aimed to investigate survival and COD in a 60-year population-based MS cohort compared with the general population. METHODS: All patients with incident multiple sclerosis (MS) (N=1388) with onset during 1953-2012 in Hordaland County, Western Norway, were included. Data were obtained from patient records at Haukeland University Hospital and linked to the Norwegian COD registry...
April 1, 2017: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/28343052/season-of-treatment-initiation-with-antidepressants-and-suicidal-behavior-a-population-based-cohort-study-in-sweden
#18
Georgios D Makris, Johan Reutfors, Morten Andersen, Richard A White, Lisa Ekselius, Fotios C Papadopoulos
BACKGROUND: Decreased binding capacity of SERT in the prefrontal cortex has been observed in both suicide victims and suicide attempters. Moreover, some studies have shown that SERT has a seasonal variation with lower binding capacity in the spring and summer, which coincides with a seasonal peak of suicides. Our aim was to explore whether the season of treatment initiation with antidepressants is associated with suicide or suicide attempt and compare it with the underlying suicide seasonality in the general population...
March 10, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28330589/ethnicity-and-excess-mortality-in-severe-mental-illness-a-cohort-study
#19
Jayati Das-Munshi, Chin-Kuo Chang, Rina Dutta, Craig Morgan, James Nazroo, Robert Stewart, Martin J Prince
BACKGROUND: Excess mortality in severe mental illness (defined here as schizophrenia, schizoaffective disorders, and bipolar affective disorders) is well described, but little is known about this inequality in ethnic minorities. We aimed to estimate excess mortality for people with severe mental illness for five ethnic groups (white British, black Caribbean, black African, south Asian, and Irish) and to assess the association of ethnicity with mortality risk. METHODS: We conducted a longitudinal cohort study of individuals with a valid diagnosis of severe mental illness between Jan 1, 2007, and Dec 31, 2014, from the case registry of the South London and Maudsley Trust (London, UK)...
March 16, 2017: Lancet Psychiatry
https://www.readbyqxmd.com/read/28327056/multiple-sclerosis-and-suicide
#20
Anthony Feinstein, Bennis Pavisian
Mortality rates are elevated in people with multiple sclerosis (MS) relative to the general population. There is, however, some uncertainty whether suicide contributes to this. Epidemiological data suggest that the standardized mortality ratio (SMR) for suicide in MS is approximately twice that of the general population with younger males in the first few years following diagnosis most at risk. Rates of suicidal intent, a potential harbinger of more self-destructive behavior, are also elevated, but the frequency with which intent is followed by suicide is not known...
March 1, 2017: Multiple Sclerosis: Clinical and Laboratory Research
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