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https://www.readbyqxmd.com/read/28214712/epidemiological-study-of-mortality-in-epilepsy-in-a-spanish-population
#1
María Isabel Chamorro-Muñoz, Guillermina García-Martín, Francisco Pérez-Errazquin, Manuel Romero-Acebal, Antonio García-Rodríguez, Mario Gutiérrez-Bedmar
PURPOSE: Studies concerning mortality in epilepsy have been performed primarily in Northern-Central Europe and US. The aim of this study was to provide information about mortality in people with epilepsy in Southern European countries. METHOD: We studied a Spanish prevalence and incidence cohort of 2309 patients aged ≥14 years with epilepsy who were treated in an outpatient epilepsy clinic between 2000 and 2013. The deceased were identified through Civil Registries...
February 8, 2017: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/28210174/anterior-segment-optical-coherence-tomography-changes-with-introduction-and-discontinuation-of-tamsulosin
#2
Abdullah Al-Kharashi, Amir A Azimzadeh, Jerry Leung, Sidney Radomski, Lenny Radomski, Wai-Ching Lam
PURPOSE: The aim of this study was to quantify changes and reversibility in pupil dilation and iris dilator muscle region thickness associated with introduction and subsequent discontinuation of tamsulosin in patients naïve to this drug with the aid of an anterior OCT system. METHODS: The study was carried out on 7 patients (14 eyes) naïve to tamsulosin and with benign prostatic hypertrophy (BHP). Measurements taken by Vistante OCT were done pre- and post-dilation of the following: pupil size, iris dilator muscle region (DMR) thickness, sphincter muscle region (SMR) thickness, and anterior chamber depth...
July 2016: Saudi Journal of Ophthalmology: Official Journal of the Saudi Ophthalmological Society
https://www.readbyqxmd.com/read/28182696/ontogenetic-comparisons-of-standard-metabolism-in-three-species-of-crocodilians
#3
C M Gienger, Matthew L Brien, Christopher R Tracy, S Charlie Manolis, Grahame J W Webb, Roger S Seymour, Keith A Christian
Due in part to their large size, aggressive temperament, and difficulty in handling, there are few physiological studies of adult crocodilians in the literature. As a result, studies comparing individuals across an ontogenetic series and comparisons among species are also lacking. We addressed this gap in knowledge by measuring standard metabolic rates (SMR) of three species of crocodilians (Crocodylus porosus, C. johnsoni, and Alligator mississippiensis), and included individuals that ranged from 0.22 to 114 kg...
2017: PloS One
https://www.readbyqxmd.com/read/28181332/impact-of-universal-health-coverage-on-suicide-risk-in-newly-diagnosed-cancer-patients-population-based-cohort-study-from-1985-to-2007-in-taiwan
#4
Po-Hsien Lin, Shih-Cheng Liao, I-Ming Chen, Po-Hsiu Kuo, Jia-Chi Shan, Ming-Been Lee, Wei J Chen
BACKGROUND: National Health Insurance (NHI), launched in 1995 in Taiwan, lightens patient's financial burdens but its effect on the suicide risk in cancer patients is unclear. We aimed to investigate the impacts of the NHI on the suicide in newly diagnosed cancer patients. METHODS: We identified patients with newly diagnosed cancer from the nationwide Taiwan Cancer Registration from 1985 to 2007, and ascertained suicide deaths from the national database of registered deaths between 1985 and 2009...
February 8, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/28167782/ppr-smr-protein-sot1-has-rna-endonuclease-activity
#5
Wen Zhou, Qingtao Lu, Qingwei Li, Lei Wang, Shunhua Ding, Aihong Zhang, Xiaogang Wen, Lixin Zhang, Congming Lu
Numerous attempts have been made to identify and engineer sequence-specific RNA endonucleases, as these would allow for efficient RNA manipulation. However, no natural RNA endonuclease that recognizes RNA in a sequence-specific manner has been described to date. Here, we report that SUPPRESSOR OF THYLAKOID FORMATION 1 (SOT1), an Arabidopsis pentatricopeptide repeat (PPR) protein with a small MutS-related (SMR) domain, has RNA endonuclease activity. We show that the SMR moiety of SOT1 performs the endonucleolytic maturation of 23S and 4...
February 6, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28162109/anorexia-nervosa-in-males-excess-mortality-and-psychiatric-co-morbidity-in-609-swedish-in-patients
#6
J Kask, M Ramklint, N Kolia, D Panagiotakos, A Ekbom, L Ekselius, F C Papadopoulos
BACKGROUND: Anorexia nervosa (AN) is a psychiatric disorder with high mortality. METHOD: A retrospective register study of 609 males who received hospitalized care for AN in Sweden between 1973 and 2010 was performed. The standardized mortality ratios (SMRs) and Cox regression-derived hazard ratios (HRs) were calculated as measures of mortality. The incidence rate ratios (IRRs) were calculated to compare the mortality rates in patients with AN and controls both with and without psychiatric diagnoses...
February 6, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28161192/eeg-based-zero-phase-phase-locking-value-plv-and-effects-of-spatial-filtering-during-actual-movement
#7
Wenjuan Jian, Minyou Chen, Dennis J McFarland
Phase-locking value (PLV) is a well-known feature in sensorimotor rhythm (SMR) based BCI. Zero-phase PLV has not been explored because it is generally regarded as the result of volume conduction. Because spatial filters are often used to enhance the amplitude (square root of band power (BP)) feature and attenuate volume conduction, they are frequently applied as pre-processing methods when computing PLV. However, the effects of spatial filtering on PLV are ambiguous. Therefore, this article aims to explore whether zero-phase PLV is meaningful and how this is influenced by spatial filtering...
February 1, 2017: Brain Research Bulletin
https://www.readbyqxmd.com/read/28159024/excess-long-term-mortality-among-hospital-survivors-of-acute-myocardial-infarction-soroka-acute-myocardial-infarction-sami-project
#8
Y Plakht, H Gilutz, A Shiyovich
OBJECTIVES: We evaluated long-term survival after acute myocardial infarction (AMI) in unselected 'real life' patients according to the various risk groups, and it's persistence with time after AMI as compared with the matched general population. STUDY DESIGN: Retrospective study. METHODS: Data were collected from 2671 AMI hospital survivors (tertiary medical centre in Israel), which included demographics, clinical characteristics of AMI, comorbidities, interventions and test results...
February 2017: Public Health
https://www.readbyqxmd.com/read/28139266/-characteristics-diseases-and-mortality-of-people-admitted-to-nursing-homes-for-dependent-seniors-during-the-first-quarter-of-2013%C3%A2-in-france
#9
A Atramont, A Rigault, S Chevalier, G Leblanc, A Fagot-Campagna, P Tuppin
BACKGROUND: To describe the state of health, through healthcare consumption and mortality, of people admitted to nursing homes (Ehpad) in France. METHODS: People over the age of 65 years admitted to an Ehpad institution during the first quarter of 2013, beneficiaries of the national health insurance general scheme (69% of the population of this age), were identified from the Resid-Ehpad database and their reimbursed health care was extracted from the SNIIRAM database, identifying 56 disease groups by means of algorithms (long-term disease diagnoses and hospitalisations, medicinal products, specific procedures)...
January 27, 2017: Revue D'épidémiologie et de Santé Publique
https://www.readbyqxmd.com/read/28138339/well-to-wake-analysis-of-ethanol-to-jet-and-sugar-to-jet-pathways
#10
Jeongwoo Han, Ling Tao, Michael Wang
BACKGROUND: To reduce the environmental impacts of the aviation sector as air traffic grows steadily, the aviation industry has paid increasing attention to bio-based alternative jet fuels (AJFs), which may provide lower life-cycle petroleum consumption and greenhouse gas (GHG) emissions than petroleum jet fuel. This study presents well-to-wake (WTWa) results for four emerging AJFs: ethanol-to-jet (ETJ) from corn and corn stover, and sugar-to-jet (STJ) from corn stover via both biological and catalytic conversion...
2017: Biotechnology for Biofuels
https://www.readbyqxmd.com/read/28130043/prevalence-age-at-diagnosis-mortality-and-cause-of-death-in-retinitis-pigmentosa-in-korea-a-nationwide-population-based-study
#11
Kun-Hoo Na, Hyun Jung Kim, Kyoung Hoon Kim, Seungjin Han, Patrick Kim, Hoo Jae Hann, Hyeong Sik Ahn
PURPOSE: To determine the prevalence and mortality of retinitis pigmentosa (RP) patients in Korea. DESIGN: Population-based retrospective cohort study METHODS: We used data covering the 2011-2014 period from the Rare Intractable Disease (RID) registry and Health Insurance Review Agency (HIRA), which include information on all patients diagnosed with RP based on predefined diagnostic criteria. Using the HIRA-RID database, the prevalence and age at diagnosis of RP patients across the entire Korean population were evaluated...
January 24, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28125763/continued-treatment-effect-of-zoledronic-acid-dosing-every-12-vs-4-weeks-in-women-with-breast-cancer-metastatic-to-bone-the-optimize-2-randomized-clinical-trial
#12
Gabriel N Hortobagyi, Catherine Van Poznak, W Graydon Harker, William J Gradishar, Helen Chew, Shaker R Dakhil, Barbara B Haley, Nicholas Sauter, Ramon Mohanlal, Ming Zheng, Allan Lipton
Importance: Zoledronic acid, a potent bisphosphonate, is commonly administered to patients with bone metastases to reduce the risk of skeletal-related events (SREs). However, there have been concerns regarding its long-term monthly administration. Objective: To examine whether zoledronic acid every 12 weeks was noninferior to zoledronic acid every 4 weeks in patients with metastatic breast cancer that involved the bone who had previously received a standard dosing regimen of zoledronic acid and/or pamidronate disodium...
January 26, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/28122696/neurofeedback-as-a-treatment-for-impulsivity-in-a-forensic-psychiatric-population-with-substance-use-disorder-study-protocol-of-a-randomized-controlled-trial-combined-with-an-n-of-1-clinical-trial
#13
Sandra Fielenbach, Franc Cl Donkers, Marinus Spreen, Stefan Bogaerts
BACKGROUND: Impulsivity and substance use disorder (SUD) are strongly interconnected, with persons scoring high on impulsivity being more vulnerable to develop substance abuse, facing more challenges for successful treatment, and being more prone to engage in criminal behavior. Studies have shown that impulsivity and craving for substances are strongly correlated. Neurofeedback is an effective treatment to reduce impulsive behavior. This study intends to determine to what extent a neurofeedback-intervention that is aimed at reducing impulsivity can also reduce levels of craving in forensic patients with SUD and comorbid Axis I and/or II diagnoses...
January 25, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28115137/use-of-sub-micron-sized-resin-particles-for-removal-of-endocrine-disrupting-compounds-and-pharmaceuticals-from-water-and-wastewater
#14
Audrey Murray, Banu Örmeci, Edward P C Lai
Endocrine disrupting compounds (EDCs) and pharmaceuticals pose a challenge for water and wastewater treatment because they exist at very low concentrations in the presence of substances at much higher concentrations competing for adsorption sites. Sub-micron sized resin particles (approximately 300nm in diameter) (SMR) were tested to evaluate their potential as a treatment for EDCs including: 17-β estradiol (E2), 17-α ethinylestradiol (EE2), estrone (E1), bisphenol A (BPA), and diethylstilbestrol (DES) as well as 12 pharmaceuticals...
January 2017: Journal of Environmental Sciences (China)
https://www.readbyqxmd.com/read/28113494/switchable-and-tunable-baw-duplexer-based-on-ferroelectric-material
#15
Almonir Mansour, Thottam Kalkur
A switchable and tunable BAW duplexer for RF applications is presented in this paper. The fabricated BAW duplexer was built on sapphire substrate using solidly mounted resonators (SMR). A metalorganic solution deposition (MOSD) technique was used to form resonators with barium strontium titanate (BST) thin film and six layers of silicon dioxide and tantalum oxide as a Bragg reflector. By applying DC bias, the BST thin film shows an electrostrictive effect, and the two filter paths of the BAW duplexer switch to band pass response with center frequencies at 4...
October 4, 2016: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28109473/competing-causes-of-death-in-the-head-and-neck-cancer-population
#16
Sean T Massa, Nosayaba Osazuwa-Peters, Kara M Christopher, Lauren D Arnold, Mario Schootman, Ronald J Walker, Mark A Varvares
PURPOSE/OBJECTIVES: The increasing survivorship of head and neck squamous cell carcinoma (HNSCC) comes with a risk of death from other causes, known as competing causes. The demographics of HNSCC are also evolving with increasing incidence of Human Papillomavirus (HPV) associated tumors. This study describes competing causes of death for the HNSCC population compared to the general population and identifies associated risk factors. METHODS: Adult patients with first mucosal HNSCC (2004-2011) were identified from the Surveillance, Epidemiology and End Result database...
February 2017: Oral Oncology
https://www.readbyqxmd.com/read/28095723/increased-long-term-mortality-after-survival-of-invasive-pneumococcal-disease-a-population-based-study
#17
Hans Kristian Floeystad, Are Holm, Leiv Sandvik, Didrik Frimann Vestrheim, Bjorn Brandsaeter, Dag Berild
OBJECTIVES: We studied if patients surviving hospitalization for invasive pneumococcal disease (IPD) have an increased long-term mortality. METHODS: In this population-based case-control study, we assessed adults discharged from Aker University Hospital in Oslo, Norway, from 1993 to 2008 after surviving IPD. Mortality among the study population was compared to the general Norwegian population using standardized mortality ratios (SMR). Median follow-up time was 7...
January 17, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28093595/mortality-and-cause-of-death-in-israeli-patients-with-pemphigus
#18
Khalaf Kridin, Shira Zelber Sagi, Reuven Bergman
All-cause and cause-specific mortality among patients with pemphigus compared with the general population is yet to be established. This study investigated overall mortality and cause-specific mortality in a large immunopathologically validated cohort of patients with pemphigus. Mortality of patients with pemphigus was compared with age- and gender-matched control subjects in the general population. All-cause and cause-specific standardized mortality ratios (SMRs) were estimated. The study cohort included 245 patients newly-diagnosed with pemphigus between January 1990 and June 2016...
January 17, 2017: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/28077469/risk-factors-for-excess-mortality-in-adults-with-congenital-heart-diseases
#19
Jose Maria Oliver, Pastora Gallego, Ana Elvira Gonzalez, Diego Garcia-Hamilton, Pablo Avila, Raquel Yotti, Ignacio Ferreira, Francisco Fernandez-Aviles
AIMS: To examine factors related to excess mortality in a cohort of adults with congenital heart disease (CHD). METHODS AND RESULTS: We conducted a survival analysis using prospective data of 3311 adults with CHD [50.5% males, median age at entry 22.5 years (IQR 18-39), median follow-up time 10.5 years (IQR: 4.4-18)]. Survival status of each patient was further verified by cross checking with the Spanish National Death Index. During a total follow-up of 37608 person-years, 336 (10%) patients died...
January 10, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28076321/secretion-modification-region-derived-peptide-blocks-exosome-release-and-mediates-cell-cycle-arrest-in-breast-cancer-cells
#20
Ming-Bo Huang, Ruben R Gonzalez, James Lillard, Vincent C Bond
PURPOSE: Discovery and development of a novel anticancer PEG-SMR-Clu peptide to prevent breast cancer metastasis. How breast cancer cells and primary mammary epithelial cells interact and communicate with each other to promote tumorigenesis and how to prevent tumor metastasis has long been a concern of researchers. Cancer cells secrete exosomes containing proteins and RNA. These factors can influence tumor development by directly targeting cancer cells and tumor stroma. In this study, we determined the effects of a peptide as an inhibitor of exosome secretion on breast tumors...
January 5, 2017: Oncotarget
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