keyword
https://read.qxmd.com/read/38628390/development-of-a-novel-endoscopic-hemostasis-assisted-navigation-ai-system-in-the-standardization-of-post-esd-coagulation
#1
JOURNAL ARTICLE
Haruka Fujinami, Shun Kuraishi, Akira Teramoto, Seitaro Shimada, Saeko Takahashi, Takayuki Ando, Ichiro Yasuda
Background and study aims While gastric endoscopic submucosal dissection (ESD) has become a treatment with fewer complications, delayed bleeding remains a challenge. Post-ESD coagulation (PEC) is performed to prevent delayed bleeding. Therefore, we developed an artificial intelligence (AI) to detect vessels that require PEC in real time. Materials and methods Training data were extracted from 153 gastric ESD videos with sufficient images taken with a second-look endoscopy (SLE) and annotated as follows: (1) vessels that showed bleeding during SLE without PEC; (2) vessels that did not bleed during SLE with PEC; and (3) vessels that did not bleed even without PEC...
April 2024: Endoscopy International Open
https://read.qxmd.com/read/38411228/on-the-utmost-importance-of-the-geometry-factor-of-accuracy-in-the-quantum-chemical-calculations-of-31p-nmr-chemical-shifts-new-efficient-pecg-n-n-1-2-basis-sets-for-the-geometry-optimization-procedure
#2
JOURNAL ARTICLE
Yu Yu Rusakov, Yu A Nikurashina, I L Rusakova
31P nuclear magnetic resonance (NMR) chemical shifts were shown to be very sensitive to the basis set used at the geometry optimization stage. Commonly used energy-optimized basis sets for a phosphorus atom containing only one polarization d-function were shown to be unable to provide correct equilibrium geometries for the calculations of phosphorus chemical shifts. The use of basis sets with at least two polarization d-functions on a phosphorus atom is strongly recommended. In this paper, an idea of creating the basis sets purposed for the geometry optimization that provide the least possible error coming from the geometry factor of accuracy in the resultant NMR shielding constants is proposed...
February 28, 2024: Journal of Chemical Physics
https://read.qxmd.com/read/37888041/evaluation-of-the-efficacy-of-pectoral-nerve-2-block-pecs-2-in-breast-cancer-surgery
#3
JOURNAL ARTICLE
Jolanta Cylwik, Małgorzata Celińska-Spodar, Natalia Buda
This study aimed to evaluate the efficacy of the pectoral nerves interfacial plane block (PECS II) in breast cancer surgery focusing on postoperative pain management and patient satisfaction. A prospective study was conducted, including 200 patients scheduled for breast cancer surgery. The participants were randomly assigned to the PECS II block and control groups. The PECS II block group received a preoperative interfascial plane block, while the control group received standard analgesia. Postoperative pain scores at 4 h intervals for the first 3 postoperative days, as well as opioid consumption and patient-reported satisfaction, were measured and compared between both groups...
September 24, 2023: Journal of Personalized Medicine
https://read.qxmd.com/read/37834068/on-the-efficiency-of-the-density-functional-theory-dft-based-computational-protocol-for-1-h-and-13-c-nuclear-magnetic-resonance-nmr-chemical-shifts-of-natural-products-studying-the-accuracy-of-the-pecs-n-n-1-2-basis-sets
#4
JOURNAL ARTICLE
Yuriy Yu Rusakov, Valentin A Semenov, Irina L Rusakova
The basis set issue has always been one of the most important factors of accuracy in the quantum chemical calculations of NMR chemical shifts. In a previous paper, we developed new pecS- n ( n = 1, 2) basis sets purposed for the calculations of the NMR chemical shifts of the nuclei of the most popular NMR-active isotopes of 1-2 row elements and successfully approbated these on the DFT calculations of chemical shifts in a limited series of small molecules. In this paper, we demonstrate the performance of the pecS- n ( n = 1, 2) basis sets on the calculations of as much as 713 1 H and 767 13 C chemical shifts of 23 biologically active natural products with complicated stereochemical structures, carried out using the GIAO-DFT(PBE0) approach...
September 27, 2023: International Journal of Molecular Sciences
https://read.qxmd.com/read/37598828/transcriptome-analysis-reveals-the-role-of-polysaccharide-biosynthesis-in-the-detoxification-of-dendrobium-nobile-under-zinc-stress
#5
JOURNAL ARTICLE
Yijun Fan, Xuebing Li, Gang Wang, Jie Ma, Yuanyuan Liu, Erya Xu, Aoxue Luo
Plants can bind excessive heavy metals by synthesizing compounds to alleviate the harm caused by heavy metals. To reveal the mechanism by which Dendrobium nobile alleviates zinc stress, metabolome combined transcriptome analysis was used in this research. The results showed that zinc was mainly enriched in the roots and leaves and the biomass of the roots and leaves of D. nobile decreased significantly by 18.21 % and 49.22 % (P < 0.05) compared to the control (CK), respectively...
August 18, 2023: International Journal of Biological Macromolecules
https://read.qxmd.com/read/37489053/activity-relationship-of-poly-ethylenimine-based-liposomes-as-group-a-streptococcus-vaccine-delivery-systems
#6
JOURNAL ARTICLE
Shengbin Jin, Jiahui Zhang, Ummey J Nahar, Wenbin Huang, Nedaa A Alharbi, Ahmed O Shalash, Prashamsa Koirala, Jieru Yang, Jolynn J E Kiong, Zeinab G Khalil, Robert J Capon, Rachel J Stephenson, Mariusz Skwarczynski, Istvan Toth, Waleed M Hussein
Untreated group A Streptococcus (GAS) can lead to a range of life-threatening diseases, including rheumatic heart disease. To date, no therapeutic or prophylactic vaccines are commercially available to treat or prevent GAS infection. Development of a peptide-based subunit vaccine offers a promising solution, negating the safety issues of live-attenuated or inactive vaccines. Subunit vaccines administer small peptide fragments (antigens), which are typically poorly immunogenic. Therefore, these peptide antigens require formulation with an immune stimulant and/or vaccine delivery platform to improve their immunogenicity...
July 24, 2023: ACS Infectious Diseases
https://read.qxmd.com/read/37409722/new-efficient-pecs-n-n-1-2-basis-sets-for-quantum-chemical-calculations-of-31-p-nmr-chemical-shifts
#7
JOURNAL ARTICLE
Yuriy Yu Rusakov, Irina L Rusakova
The basis sets that are used in the quantum chemical calculations of 31 P NMR chemical shifts have always been one of the most important factors of accuracy. Regardless of what high-quality approach is employed, using basis sets of insufficient flexibility in the important angular regions may give poor results and lead to misassignments of the signals in the 31 P NMR spectra. In this work, it was found that the existing nonrelativistic basis sets for phosphorus atom of double- and triple- ζ quality, specialized for the 31 P NMR chemical shifts calculations, are essentially undersaturated in the d -angular space that occurred to play a significant role in the overall accuracy of these calculations...
July 6, 2023: Physical Chemistry Chemical Physics: PCCP
https://read.qxmd.com/read/37010475/assessing-the-efficacy-of-the-s-pecs-block-in-breast-augmentation-surgery-a-randomised-double-blind-control-trial
#8
JOURNAL ARTICLE
Marcos Sforza, Reyan Saghir, Norman Saghir, Rodwan Husein, Renee Okhiria, Terrell Okhiria, Manu Sidhu, Manoj Poojary
INTRODUCTION: Postoperative acute and chronic pain following breast surgery is a common complication which needs resolving to allow for improved patient outcomes. Previously thoracic epidurals and paravertebral blocks (PVB) have been the gold standard administered intra-operatively. However, more recently the introduction of the Pectoral nerve block (PECS and PECS-2 blocks) has looked promising to control the pain more effectively, but further robust analysis is required to prove its efficacy...
April 4, 2023: Plastic and Reconstructive Surgery
https://read.qxmd.com/read/36921023/cuff-size-cuff-placement-blood-pressure-state-and-monitoring-technique-can-influence-indirect-arterial-blood-pressure-monitoring-in-anesthetized-bats-pteropus-vampyrus
#9
JOURNAL ARTICLE
Vaidehi V Paranjape, Bonnie J Gatson, Kate Bailey, James F X Wellehan
OBJECTIVE: Evaluate agreement between 2 non-invasive blood pressure (NIBP) techniques and invasive arterial blood pressure (IBP) in anesthetized bats using various cuff sizes and cuff positioning while also evaluating its performance during hypertension and hypotension. ANIMALS: 8 bats (1.1 ± 0.2 kg). PROCEDURES: Bats were anesthetized with isoflurane in oxygen. NIBP was measured using oscillometric (NIBP-O) and Doppler (NIBP-D) techniques in the pectoral limb (PEC) and pelvic limbs (PEL) using 3 cuff sizes (1, 2, and 3)...
March 19, 2023: American Journal of Veterinary Research
https://read.qxmd.com/read/36633115/less-use-of-rescue-morphine-when-a-combined-psp-ipp-block-is-used-for-postoperative-analgesia-in-breast-cancer-surgery-a-randomised-controlled-trial
#10
RANDOMIZED CONTROLLED TRIAL
Hans Ahlberg, Daniel Wallgren, Magnus Hultin, Tomi Myrberg, Joakim Johansson
BACKGROUND: Surgery for breast cancer is common, and intravenous opioids are often used to control postoperative pain. Recently, pectoralis-2 (PECS-2) block has emerged as a promising regional anaesthetic alternative. With nomenclature recently proposed, this block is termed combined PSP/IPP-block (pectoserratus plane block/interpectoral plane block). OBJECTIVE: We aimed to compare the need for postoperative rescue morphine between the intervention group that received a pre-operative combined PSP/IPP-block and a control group that received peri-operative long-acting opioids for postoperative analgesia...
September 1, 2023: European Journal of Anaesthesiology
https://read.qxmd.com/read/35778081/new-pecs-n-n-1-2-basis-sets-for-quantum-chemical-calculations-of-the-nmr-chemical-shifts-of-h-c-n-and-o-nuclei
#11
JOURNAL ARTICLE
Yuriy Yu Rusakov, Irina L Rusakova
This paper demonstrates the performance of our previously suggested property-energy consistent method on the example of the generation of effective basis sets, pecS-1 and pecS-2, suited for the calculation of hydrogen, carbon, nitrogen, and oxygen chemical shifts. The new basis sets were successfully approbated in the GIAO-DFT calculations of the chemical shifts of 35 molecules using six different functionals. The pecS-1 basis set demonstrated very good accuracy, which makes this small basis set an effective means for the large-scale computations...
June 28, 2022: Journal of Chemical Physics
https://read.qxmd.com/read/34860342/impact-of-energy-management-systems-pro-environmental-energy-consumption-and-awareness-on-performance-outcomes-a-serial-mediated-moderated-modeling-with-pls-sem
#12
JOURNAL ARTICLE
Muhsin Halis, Mine Halis
Energy consumption efficiency is gaining momentum due to climate change, increased carbon emissions by firms, and paucity of fossil fuels. Energy management systems (EMS) and environmental awareness came into the spotlight few decades ago and are said to improve energy efficiency of firms. The purpose of this paper is to unveil the association and serial mediation between EMS and firm performance through pro-environmental energy consumption (PEC) and pro-environmental energy consumption performance (PECP), and the moderating role of environmental awareness (EA)...
December 3, 2021: Environmental Science and Pollution Research International
https://read.qxmd.com/read/34669181/evaluation-of-interfascial-plane-and-pericapsular-nerve-blocks-to-the-shoulder-joint-a-preliminary-analysis-of-shoulder-anterior-capsular-block
#13
JOURNAL ARTICLE
Felice Galluccio, Mario Fajardo Perez, Ece Yamak Altinpulluk, Jin-De Hou, Jui-An Lin
INTRODUCTION: The aim of this study is to verify if the shoulder anterior capsular block (SHAC), combined with other nerve blocks, is effective in relieving shoulder pain, avoiding motor block and allowing an early rehabilitation program. METHODS: Seventy-five consecutive patients with painful shoulder were treated with the SHAC, alone (30 patients) or in combination with a suprascapular nerve block (SSnb: 25 patients) or with pectoralis and serratus plane block (PECS-2: 20 patients)...
December 2021: Pain and Therapy
https://read.qxmd.com/read/34182431/incidence-of-essential-hypertension-but-not-echocardiographic-abnormalities-at-four-years-with-a-history-of-preeclampsia-with-severe-features
#14
JOURNAL ARTICLE
Arthur Jason Vaught, Anum Minhas, Theresa Boyer, Alexia Debrosse, Garima Sharma, Dhananjay Vaidya, Pamela Ouyang, Sammy Zakaria, Monica Mukherjee
INTRODUCTION: Women with preeclampsia are more likely to have abnormal echocardiographic parameters at the time of diagnosis and are more likely to have hypertension and other cardiovascular diseases (CVD) later in life. Screening for future CVD in preeclamptic women would assist in appropriately risk stratifying and identifying high risk women for preventive management; however, the timing of screening and the screening factors are unknown. OBJECTIVE: The objectives of this project are to 1) assess incidence of essential hypertension 4 years after pregnancy in preeclampsia with severe features (PEC) 2) identify predictive echocardiographic variables at the time of PEC diagnosis and 3) assess the rate of echocardiographic abnormalities 4 years after developing PEC...
June 12, 2021: Pregnancy Hypertension
https://read.qxmd.com/read/34033000/a-novel-prognostic-tool-in-western-and-eastern-biliary-tract-cancer-patients-treated-in-first-line-setting-the-ecsipot-index
#15
JOURNAL ARTICLE
Giulia Rovesti, Francesco Leone, Giovanni Brandi, Silvia Cesario, Mario Scartozzi, Monica Niger, Changhoon Yoo, Roberto Filippi, Mariaelena Casagrande, Nicola Silvestris, Daniele Santini, Luca Faloppi, Andrea Palloni, Massimo Aglietta, Laura Bernardini, Hyungwoo Cho, Eleonora Lai, Elisabetta Fenocchio, Chiara Pircher, Donatella Iacono, Stefania De Lorenzo, Elisa Sperti, Valentina Massa, Filippo De Braud, Jae Ho Jeong, Giuseppe Aprile, Valentina Burgio, Stefano Cascinu, Andrea Casadei-Gardini
BACKGROUND AND AIM: The need to estimate prognosis of advanced BTC (aBTC) patients treated with first-line chemotherapy is compelling. The aim of the study is to evaluate the ECSIPOT (psECogSIiPnigOT) index, influenced by PECS (PsECogSii) index, prognostic nutritional index (PNI), and GOT. METHODS: This international study was conducted on a training cohort of 126 patients and in three validation cohorts, both European and Korean. ECSIPOT index formula: (PECS:0 = 1 point; PECS:1 = 1...
May 25, 2021: Journal of Gastrointestinal Cancer
https://read.qxmd.com/read/33554124/combined-transverse-thoracis-plane-and-pectoral-nerve-blocks-for-breast-surgery-under-sedation
#16
E J Helmich, R J Van Den Broek, J G Bloemen
The pectoral nerves 2 (pecs 2) block is widely used as adjunct to general anaesthesia for breast surgery. There are a few case reports and a single case series that describe regional anaesthesia as a single technique or supplemented by light to moderate sedation. Here we describe the management of a 91-year-old ASA physical status 4 patient who presented with a T4 breast malignancy. She was considered unfit for general anaesthesia due to significant valvular heart disease. A wide local excision was successfully performed under a pecs 2 block and a transverse thoracis plane block, supplemented with light sedation...
January 2021: Anaesthesia reports
https://read.qxmd.com/read/33544375/prognostic-role-of-a-new-index-tested-in-european-and-korean-advanced-biliary-tract-cancer-patients-the-pecs-index
#17
JOURNAL ARTICLE
Giulia Rovesti, Francesco Leone, Giovanni Brandi, Lorenzo Fornaro, Mario Scartozzi, Monica Niger, Changhoon Yoo, Francesco Caputo, Roberto Filippi, Mariaelena Casagrande, Nicola Silvestris, Daniele Santini, Luca Faloppi, Andrea Palloni, Massimo Aglietta, Caterina Vivaldi, Hyungwoo Cho, Eleonora Lai, Elisabetta Fenocchio, Federico Nichetti, Nicoletta Pella, Stefania De Lorenzo, Massimo Di Maio, Enrico Vasile, Filippo de Braud, Jae Ho Jeong, Giuseppe Aprile, Giulia Orsi, Stefano Cascinu, Andrea Casadei-Gardini
BACKGROUND AND AIM: The aim of the present study is to evaluate a new index (PECS (PsECogSii)index) influenced by PS ECOG and systemic immune-inflammation index (SII) in unresectable locally advanced or metastatic BTC patients treated with first-line chemotherapy. METHODS: This multicenter, international, study was conducted on a training cohort of 130 patients and in three European and Korean validation cohorts The PECS index was calculated as ECOG × SII index (neutrophil count × platelet count/lymphocyte count)...
February 5, 2021: Journal of Gastrointestinal Cancer
https://read.qxmd.com/read/32913363/evaluation-of-strategies-using-simulation-model-to-control-a-potential-outbreak-of-highly-pathogenic-avian-influenza-among-poultry-farms-in-central-luzon-philippines
#18
JOURNAL ARTICLE
Roderick Salvador, Neil Tanquilut, Rosemarie Macmac, Kannika Na Lampang, Warangkhana Chaisowwong, Dirk Pfeiffer, Veerasak Punyapornwithaya
The Philippines confirmed its first epidemic of Highly Pathogenic Avian Influenza (HPAI) on August 11, 2017. It ended in November of 2017. Despite the successful management of the epidemic, reemergence is a continuous threat. The aim of this study was to conduct a mathematical model to assess the spatial transmission of HPAI among poultry farms in Central Luzon. Different control strategies and the current government protocol of 1 km radius pre-emptive culling (PEC) from infected farms were evaluated. The alternative strategies include 0...
2020: PloS One
https://read.qxmd.com/read/32677623/improving-the-management-effectiveness-and-decision-making-by-stakeholders-perspectives-a-case-study-in-a-protected-area-from-the-brazilian-atlantic-forest
#19
JOURNAL ARTICLE
Marcondes Geraldo Coelho Junior, Bárbara Pavani Biju, Eduardo Carvalho da Silva Neto, Athila Leandro de Oliveira, Ana Alice de Oliveira Tavares, Vanessa Maria Basso, Ana Paula Dias Turetta, Acacio Geraldo de Carvalho, Jerônimo Boelsums Barreto Sansevero
Assessing management effectiveness in protected areas is a fundamental instrument to achieve socio-biodiversity protection goals. This study aimed to analyze the management effectiveness of Cunhambebe State Park (from now on, "PEC") in the State of Rio de Janeiro in Brazil, from the perception of stakeholders and the multi-temporal analysis of land use and land cover between 1998 and 2018. We used the Rapid Assessment and Prioritization of Protected Area Management method for a participatory approach...
July 15, 2020: Journal of Environmental Management
https://read.qxmd.com/read/32109825/analgesic-efficacy-of-pecs-and-serratus-plane-blocks-after-breast-surgery-a-systematic-review-meta-analysis-and-trial-sequential-analysis
#20
REVIEW
Sina Grape, Eric Jaunin, Kariem El-Boghdadly, Vincent Chan, Eric Albrecht
STUDY OBJECTIVE: To determine whether pectoral nerves (PECS) blocks provide effective postoperative analgesia when compared with no regional technique in patients undergoing breast surgery. DESIGN: Systematic review, meta-analysis and trial sequential analysis. SETTING: Operating room, postoperative recovery area and ward, up to 24 postoperative hours. PATIENTS: Patients undergoing breast surgery under general anaesthesia with either PECS block or no regional technique...
August 2020: Journal of Clinical Anesthesia
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