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https://www.readbyqxmd.com/read/27922876/mothers-weaning-practices-when-infants-breastfeed-for-more-than-one-year
#1
Addie Cunniff, Diane Spatz
The American Academy of Pediatrics and the World Health Organization recommend that infants receive human milk exclusively for the first 6 months of life and that breastfeeding continue beyond the first or second year of life for as long as a family deems appropriate. More infants in the United States and around the world are meeting this recommendation. As more infants breastfeed beyond the first year of life, best practices for weaning toddlers come into question. Little is known about concerns and practices of breastfeeding mothers weaning their children from feedings...
December 5, 2016: MCN. the American Journal of Maternal Child Nursing
https://www.readbyqxmd.com/read/27920758/effectiveness-of-f18-fimbrial-antigens-released-by-a-novel-autolyzed-salmonella-expression-system-as-a-vaccine-candidate-against-lethal-f18-stec-infection
#2
Gayeon Won, John H Lee
Porcine edema disease (ED) caused by Shiga toxin 2e producing Escherichia coli expressing F18ab(+) fimbriae (F18ab(+)STEC) frequently occurs in post-weaned piglets, resulting in a significant economic loss in swine industries worldwide. In the present study, we proposed an efficient prevention scheme against ED in which the attenuated Salmonella Typhimurium inactivated by the E-mediated cell lysis to deliver target antigens, FedF and FedA, which function in fimbrial-mediated adhesion and as a major subunit of F18ab+fimbriae, respectively...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27920706/ipilimumab-induced-enteritis-without-colitis-a-new-challenge
#3
Marcus Messmer, Sunita Upreti, Yaman Tarabishy, Nikhilesh Mazumder, Reezwana Chowdhury, Mark Yarchoan, Matthias Holdhoff
INTRODUCTION: Ipilimumab is an immune checkpoint inhibitor targeting cytotoxic T-lymphocyte associated antigen 4 (CTLA4), approved to treat metastatic melanoma. It was the first therapy shown to prolong survival in a large, randomized clinical trial. However, immune-related adverse events are common and can be severe. Enterocolitis is a common adverse event with ipilimumab, but enteritis without colitis has not been previously described. CASE REPORT: An 83-year-old man presented to our hospital with grade 3 diarrhea for 5 days...
September 2016: Case Reports in Oncology
https://www.readbyqxmd.com/read/27918394/does-acetazolamide-really-promote-ventilator-weaning-in-critically-ill-children-with-metabolic-alkalosis
#4
Paul M Shore
No abstract text is available yet for this article.
December 2016: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/27918385/neurally-adjusted-ventilatory-assist-in-preterm-infants-with-established-or-evolving-bronchopulmonary-dysplasia-on-high-intensity-mechanical-ventilatory-support-a-single-center-experience
#5
Young Hwa Jung, Han-Suk Kim, Juyoung Lee, Seung Han Shin, Ee-Kyung Kim, Jung-Hwan Choi
OBJECTIVES: The aim of the present study was to report possible improvements in ventilator variables associated with a transition from synchronized intermittent mandatory ventilation to neurally adjusted ventilatory assist in preterm infants with bronchopulmonary dysplasia who required a high level of mechanical ventilatory support in a single center. DESIGN: Retrospective study. SETTING: Neonatal ICU. PATIENTS: Twenty-nine preterm infants with a median gestational age of 25...
December 2016: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/27917972/pastoralism-in-the-drylands-of-latin-america-argentina-chile-mexico-and-peru
#6
J M Grünwaldt, G Castellaro, E R Flores, C R Morales-Nieto, R D Valdez-Cepeda, J C Guevera, E G Grünwaldt
This article discusses various aspects of pastoralism in the Latin American countries with the largest dryland areas. The topics covered include: social, economic and institutional issues; grasslands and their carrying capacity; production systems and productivity rates; competition for forage resources between domestic livestock and wildlife; and the health status of livestock and wildlife. Most grasslands exhibit some degree of degradation. The percentage of offspring reaching weaning age is low: 47-66% of calves and 40-80% of lambs...
November 2016: Revue Scientifique et Technique
https://www.readbyqxmd.com/read/27917741/the-behaviour-and-welfare-of-sows-and-piglets-in-farrowing-crates-or-lactation-pens
#7
C Singh, M Verdon, G M Cronin, P H Hemsworth
Temporary confinement during parturition and early postpartum may provide an intermediary step preceding loose housing that offers improvement in sow and piglet welfare. Three experiments were conducted to investigate the implications of replacing farrowing crates (FCs) with an alternative housing system from 3 days postpartum until weaning. In each experiment sows farrowed in FCs and were randomly allocated at day 3 of lactation to either a FC or a pen with increased floor space (lactation pen (LP)) until weaning...
December 5, 2016: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/27917383/hakim-adams-syndrome-an-unusual-cause-of-reversible-postoperative-coma
#8
Mohamed Saleh, Marine Bouex
We report the case of a 72-year-old patient presenting in our ICU with persistent postoperative coma in a context of recent unexplored neurological dysfunction. Detailed medical history taking from the patient's family revealed he recently suffered from gait instability, urinary incontinence, and slight cognitive impairment. These constituted the clinical triad of normal pressure hydrocephalus syndrome. The presence of normal cerebrospinal fluid (CSF) pressure and distinctive radiological findings confirmed the diagnosis of normal pressure hydrocephalus or Hakims-Adams syndrome...
2016: Frontiers in Medicine
https://www.readbyqxmd.com/read/27917127/maternal-high-fat-diet-alters-skeletal-muscle-mitochondrial-catalytic-activity-in-adult-male-rat-offspring
#9
Chantal A Pileggi, Christopher P Hedges, Stephanie A Segovia, James F Markworth, Brenan R Durainayagam, Clint Gray, Xiaoyuan D Zhang, Matthew P G Barnett, Mark H Vickers, Anthony J R Hickey, Clare M Reynolds, David Cameron-Smith
A maternal high-fat (HF) diet during pregnancy can lead to metabolic compromise, such as insulin resistance in adult offspring. Skeletal muscle mitochondrial dysfunction is one mechanism contributing to metabolic impairments in insulin resistant states. Therefore, the present study aimed to investigate whether mitochondrial dysfunction is evident in metabolically compromised offspring born to HF-fed dams. Sprague-Dawley dams were randomly assigned to receive a purified control diet (CD; 10% kcal from fat) or a high fat diet (HFD; 45% kcal from fat) for 10 days prior to mating, throughout pregnancy and during lactation...
2016: Frontiers in Physiology
https://www.readbyqxmd.com/read/27916888/a-topographical-atlas-of-shiga-toxin-2e-receptor-distribution-in-the-tissues-of-weaned-piglets
#10
Daniel Steil, Robert Bonse, Iris Meisen, Gottfried Pohlentz, German Vallejo, Helge Karch, Johannes Müthing
Shiga toxin (Stx) 2e of Stx-producing Escherichia coli (STEC) is the primary virulence factor in the development of pig edema disease shortly after weaning. Stx2e binds to the globo-series glycosphingolipids (GSLs) globotriaosylceramide (Gb3Cer, Galα1-4Galβ1-4Glcβ1-1Cer) and globotetraosylceramide (Gb4Cer, GalNAcβ1-3Galα1-4Galβ1-4Glcβ1-1Cer), the latter acting as the preferential Stx2e receptor. We determined Stx receptor profiles of 25 different tissues of a male and a female weaned piglet using immunochemical solid phase binding assays combined with mass spectrometry...
November 30, 2016: Toxins
https://www.readbyqxmd.com/read/27916413/immunogenicity-and-protective-efficacy-of-a-single-dose-live-non-pathogenic-escherichia-coli-oral-vaccine-against-f4-positive-enterotoxigenic-escherichia-coli-challenge-in-pigs
#11
John Morris Fairbrother, Éric Nadeau, Louise Bélanger, Cindy-Love Tremblay, Danielle Tremblay, Mélanie Brunelle, Regina Wolf, Klaus Hellmann, Álvaro Hidalgo
Enterotoxigenic Escherichia coli strains expressing F4 (K88) fimbriae (F4-ETEC) are one of the most important causes of post-weaning diarrhea (PWD) in pigs. F4, a major antigen, plays an important role in the early steps of the infection. Herein, the efficacy of a live oral vaccine consisting of a non-pathogenic E. coli strain expressing F4 for protection of pigs against PWD was evaluated. Three blinded, placebo-controlled, block design, parallel-group confirmatory experiments were conducted, using an F4-ETEC PWD challenge model, each with a different vaccination-challenge interval (3, 7, and 21days)...
December 1, 2016: Vaccine
https://www.readbyqxmd.com/read/27916176/functional-assessment-and-transplantation-of-the-donor-heart-after-circulatory-death
#12
Simon J Messer, Richard G Axell, Simon Colah, Paul A White, Marian Ryan, Aravinda A Page, Barbora Parizkova, Kamen Valchanov, Christopher W White, Darren H Freed, Euan Ashley, John Dunning, Martin Goddard, Jayan Parameshwar, Christopher J Watson, Thomas Krieg, Ayyaz Ali, Steven Tsui, Stephen R Large
BACKGROUND: After a severe shortage of brain-dead donors, the demand for heart transplantation has never been greater. In an attempt to increase organ supply, abdominal and lung transplant programs have turned to the donation after circulatory-determined death (DCD) donor. However, because heart function cannot be assessed after circulatory death, DCD heart transplantation was deemed high risk and never adopted routinely. We report a novel method of functional assessment of the DCD heart resulting in a successful clinical program...
December 2016: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/27913821/theobromine-upregulates-osteogenesis-by-human-mesenchymal-stem-cells-in-vitro-and-accelerates-bone-development-in-rats
#13
Bret H Clough, Joni Ylostalo, Elizabeth Browder, Eoin P McNeill, Thomas J Bartosh, H Ralph Rawls, Tetsuo Nakamoto, Carl A Gregory
Theobromine (THB) is one of the major xanthine-like alkaloids found in cacao plant and a variety of other foodstuffs such as tea leaves, guarana and cola nuts. Historically, THB and its derivatives have been utilized to treat cardiac and circulatory disorders, drug-induced nephrotoxicity, proteinuria and as an immune-modulator. Our previous work demonstrated that THB has the capacity to improve the formation of hydroxyl-apatite during tooth development, suggesting that it may also enhance skeletal development...
December 2, 2016: Calcified Tissue International
https://www.readbyqxmd.com/read/27912960/music-intervention-during-daily-weaning-trials-a-6-day-prospective-randomized-crossover-trial
#14
Zhan Liang, Dianxu Ren, JiYeon Choi, Mary Beth Happ, Marylyn Hravnak, Leslie A Hoffman
PURPOSE: To examine the effect of patient-selected music intervention during daily weaning trials for patients on prolonged mechanical ventilation. METHODS: Using a crossover repeated measures design, patients were randomized to music vs no music on the first intervention day. Provision of music was alternated for 6 days, resulting in 3 music and 3 no music days. During weaning trials on music days, data were obtained for 30min prior to music listening and continued for 60min while patients listened to selected music (total 90min)...
December 2016: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/27911931/correction-effects-of-moderate-amounts-of-barley-in-late-pregnancy-on-growth-glucose-metabolism-and-osteoarticular-status-of-pre-weaning-horses
#15
Pauline Peugnet, Morgane Robles, Luis Mendoza, Laurence Wimel, Cédric Dubois, Michèle Dahirel, Daniel Guillaume, Sylvaine Camous, Valérie Berthelot, Marie-Pierre Toquet, Eric Richard, Charlotte Sandersen, Stéphane Chaffaux, Jean-Philippe Lejeune, Anne Tarrade, Didier Serteyn, Pascale Chavatte-Palmer
[This corrects the article DOI: 10.1371/journal.pone.0122596.].
2016: PloS One
https://www.readbyqxmd.com/read/27911843/impact-of-the-gut-microbiota-on-enhancer-accessibility-in-gut-intraepithelial-lymphocytes
#16
Nicholas P Semenkovich, Joseph D Planer, Philip P Ahern, Nicholas W Griffin, Charles Y Lin, Jeffrey I Gordon
The gut microbiota impacts many aspects of host biology including immune function. One hypothesis is that microbial communities induce epigenetic changes with accompanying alterations in chromatin accessibility, providing a mechanism that allows a community to have sustained host effects even in the face of its structural or functional variation. We used Assay for Transposase-Accessible Chromatin with high-throughput sequencing (ATAC-seq) to define chromatin accessibility in predicted enhancer regions of intestinal αβ(+) and γδ(+) intraepithelial lymphocytes purified from germ-free mice, their conventionally raised (CONV-R) counterparts, and mice reared germ free and then colonized with CONV-R gut microbiota at the end of the suckling-weaning transition...
December 1, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27909839/biventricular-support-using-a-centrifugal-pump-in-a-6%C3%A2-year-old-with-fulminant-myocarditis
#17
Hiromu Kehara, Tamaki Takano, Takamitsu Terasaki, Kenji Okada
We experienced a case of ventricular assist with both a pulsatile-flow and a continuous-flow pump in a pediatric patient, and herein report the clinical course and characteristics of the pumps. A 6-year-old female was diagnosed with fulminant myocarditis and transferred to our hospital for mechanical support. After 12 days of extracorporeal membrane oxygenation, we implanted a left ventricular assist device (LVAD) and a right ventricular assist device (RVAD) using centrifugal Gyro pumps with a membrane oxygenator in a paracorporeal fashion...
December 1, 2016: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/27909713/age-associated-differences-in-transporter-gene-expression-in-kidneys-of-male-rats
#18
Yong-Ji Xu, Yang Wang, Yuan-Fu Lu, Shang-Fu Xu, Qin Wu, Jie Liu
Kidney transporters are involved in the secretion and reabsorption of endogenous and exogenous molecules. Numerous factors may influence their expression and affect drug disposition, efficacy and toxicity. The present study aimed to examine the development‑ and age‑associated variations in primary renal transporters in rats, including 6 uptake transporters: Organic anion transporter (OAT) 1 and 3, organic cation transporter (OCT) 1, 2 and 3 and organic anion‑transporting polypeptide (OATP) 4C1, and 6 efflux transporters: Multidrug resistance protein 1 (MDR1), breast cancer resistance protein (BCRP), multidrug resistance‑associated protein (MRP) 2 and 4, and multidrug and toxin extrusion protein (MATE) 1 and 2‑K...
November 28, 2016: Molecular Medicine Reports
https://www.readbyqxmd.com/read/27909480/a-case-of-wide-complex-tachycardia-in-a-patient-with-a-biventricular-assist-device
#19
Abrams Mark P, Whang William, Iyer Vivek, Garan Hasan, Biviano Angelo
This case report highlights the variety of wide complex tachycardias, and the need for their prompt management, in the growing population of patients with circulatory support devices. We present a case that demonstrates how a wide complex supraventricular tachycardia in a patient with a biventricular assist device can be safely and effectively targeted for treatment using percutaneous radiofrequency catheter ablation, allowing for clinical improvement, weaning of RVAD treatment, and discharge home with LVAD alone...
February 2016: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/27907958/critical-care-management-after-cardiac-arrest
#20
Hans Friberg, Tobias Cronberg
Sudden cardiac arrest is a devastating event with high mortality and substantial morbidity among survivors. Early recognition and intervention to restore circulation is the primary goal; once that is achieved, the path toward a meaningful recovery starts. Initial in-hospital care is focused on emergency cardiac care, but soon there is a change to a more brain-oriented critical care including targeted temperature management, brain monitoring, sedation, and repeated neurologic assessments. In patients who show early signs of awakening from coma once sedation has been stopped, the prognosis is generally good...
December 2016: Seminars in Neurology
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