keyword
https://read.qxmd.com/read/38497203/pulmonary-edema-in-a-young-male-with-severe-uncontrolled-cardiovascular-risk-factors-and-pan-vascular-atherosclerosis-a-case-report
#1
JOURNAL ARTICLE
Andrea Palomba, Francesco Pelizzo, Mattia Canevari, Olga Vriz
Cardiovascular risk factors are the cause of atherosclerotic disease, which can involve all the elastic and muscolo-elastic arteries. The etiopathogenesis of atherosclerosis is multifactorial since genetics, lifestyle, and comorbidities can be simultaneously involved. Clinical manifestations can be heterogeneous and include myocardial infarction, stroke, aortic aneurysms, renal artery stenosis, renal insufficiency, peripheral artery disease, etc. Currently, 70% of clinical events cannot be prevented with available drug therapy, statins included, and at least 10% of coronary events occur in apparently healthy individuals in the absence of major traditional risk factors...
March 12, 2024: Monaldi Archives for Chest Disease
https://read.qxmd.com/read/38490651/improve-study-protocol-investigating-post-stroke-local-muscle-vibrations-to-promote-cerebral-plasticity-and-functional-recovery-a-single-blind-randomised-controlled-trial
#2
JOURNAL ARTICLE
Sophie Julliand, Charalambos Papaxanthis, Corentin Delphin, Anne Mock, Marc-Antoine Raumel, Mathieu Gueugnon, Paul Ornetti, Davy Laroche
INTRODUCTION: Spasticity is a frequent disabling consequence following a stroke. Local muscle vibrations (LMVs) have been proposed as a treatment to address this problem. However, little is known about their clinical and neurophysiological impacts when used repeatedly during the subacute phase post-stroke. This project aims to evaluate the effects of a 6-week LMV protocol on the paretic limb on spasticity development in a post-stroke subacute population. METHODS AND ANALYSIS: This is an interventional, controlled, randomised, single-blind (patient) trial...
March 15, 2024: BMJ Open
https://read.qxmd.com/read/38489591/dominant-cst3-variants-cause-adult-onset-leukodystrophy-without-amyloid-angiopathy
#3
JOURNAL ARTICLE
Caroline G Bergner, Marjolein Breur, M Clara Soto-Bernardini, Lisa Schäfer, Julia Lier, Diana Le Duc, Linnaeus Bundalian, Susanna Schubert, David Brenner, Friedmar R Kreuz, Björn Schulte, Quinten Waisfisz, Marianna Bugiani, Wolfgang Köhler, Heinrich Sticht, Rami Abou Jamra, Marjo S van der Knaap
Leukodystrophies are rare genetic white matter disorders that have been regarded as mainly occurring in childhood. Recent years altered this perception, as a growing number of leukodystrophies was described to have an onset at adult ages. Still, many adult patients presenting with white matter changes remain without a specific molecular diagnosis. We describe a novel adult onset leukodystrophy in 16 patients from eight families carrying one of four different stop-gain or frameshift dominant variants in the CST3 gene...
March 15, 2024: Brain
https://read.qxmd.com/read/38489200/non-immersive-virtual-reality-based-treatment-for-children-with-unilateral-cerebral-palsy-preliminary-results
#4
JOURNAL ARTICLE
Paolo Meriggi, Martina Mandalà, Mattia Randazzo, Elena Brazzoli, Anna Castagna, Valentina Di Giusto, Anna Cavallini, Alberto Marzegan, Tiziana Lencioni, Ivana Olivieri
PURPOSE: Unilateral cerebral palsy (UCP) represents about 30-40% of overall cerebral palsy diagnoses. Upper limb impairment has a significant negative impact on activities of daily living (ADL), and recent studies have shown that the use of virtual reality (VR) can increase motivation and promote an improvement in ADL. This preliminary study was aimed at exploring the acceptability and usability of a VR rehabilitation treatment, using the VITAMIN Platform, for children with UCP. A secondary goal of the study was to compare the results of usual standardized clinical scales and questionnaires with kinematic results as well as with the quantitative measures acquired by the VITAMIN platform in each exercise of the rehabilitation sessions...
March 15, 2024: Journal of Pediatric Rehabilitation Medicine
https://read.qxmd.com/read/38484202/teaching-video-neuroimage-oculomotor-abnormalities-in-patients-with-alternating-hemiplegia-of-childhood
#5
JOURNAL ARTICLE
Andréia B Azzoni, Mayara T Sakuma, Leticia P Sampaio, Claudio M De Gusmao
No abstract text is available yet for this article.
April 9, 2024: Neurology
https://read.qxmd.com/read/38471423/upper-limb-motor-dysfunction-is-associated-with-fragmented-kinetics-after-brain-injury
#6
JOURNAL ARTICLE
Emilie Mathieu, David Gasq, Sylvain Crémoux, Célia Delcamp, Camille Cormier, Philippe Pudlo, David Amarantini
BACKGROUND: Characterization of motor deficits after brain injury is important for rehabilitation personalization. While studies reported abnormalities in the kinematics of paretic and non-paretic elbow extension for patients with brain injuries, kinematic analysis is not sufficient to explore how patients deal with musculoskeletal redundancy and the energetic aspect of movement execution. Conversely, interarticular coordination and movement kinetics can reflect patients' motor strategies...
March 7, 2024: Clinical Biomechanics
https://read.qxmd.com/read/38467497/effect-of-mep-oriented-scalp-acupuncture-combined-with-transcranial-magnetic-stimulation-on-limb-motor-ability-in-patients-with-ischemic-stroke-hemiplegia
#7
RANDOMIZED CONTROLLED TRIAL
Shiyong Wu, Jianbin Zhang, Fei Zhang, Zilong Zhu, Boxun Fu
OBJECTIVES: To observe the effect of motor evoked potential (MEP)-oriented scalp acupuncture combined with transcranial magnetic stimulation (TMS) on limb motor ability in patients with ischemic stroke hemiplegia. METHODS: A total of 60 patients with ischemic stroke hemiplegia were randomized into an observation group and a control group, 30 cases in each one. In addition to the medication treatment of internal medicine and comprehensive training of hemiplegic limbs, MEP-oriented scalp acupuncture combined with TMS was applied in the observation group, conventional scalp acupuncture at bilateral anterior oblique line of parietal and temporal regions combined with TMS was applied in the control group...
March 12, 2024: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://read.qxmd.com/read/38464722/a-real-world-study-of-antifibrotic-drugs-related-adverse-events-based-on-the-united-states-food-and-drug-administration-adverse-event-reporting-system-and-vigiaccess-databases
#8
JOURNAL ARTICLE
Menglin He, Taoran Yang, Jian Zhou, Rurong Wang, Xuehan Li
Objectives: This study aims to investigate adverse events (AEs) and adverse drug reactions (ADRs) associated with pirfenidone and nintedanib, two antifibrotic drugs used to treat idiopathic pulmonary fibrosis (IPF). Methods: Reporting odds ratio (ROR) and proportional reporting ratio (PRR) analyses were conducted to assess the association between these drugs and signals at both the preferred term (PT) and system organ class (SOC) levels. Results: 55,949 reports for pirfenidone and 35,884 reports for nintedanib were obtained from the FAERS database...
2024: Frontiers in Pharmacology
https://read.qxmd.com/read/38463909/elejalde-syndrome-a-neuroectodermal-melanolysosomal-disease-a-case-report
#9
Amir Hossein Noohi, Hossein Shojaaldini Ardakani, Kiavash Khashayar, Laily Najafi
BACKGROUND: Elejalde syndrome is a rare neuroectodermal melanolysosomal disease with an autosomal recessive heredity. Patients usually present with silvery-gray hair, neurological abormalities, diffuse skin hypopigmentation and suntanned skin color. CASE PRESENTATION: A 3 1/2-year-old boy presented with hemiplegia since the day before admission. Durig hospital admission, he experienced episodes of status epilepticus and loss of consciousness and underwent mechanical ventilation...
2024: Caspian Journal of Internal Medicine
https://read.qxmd.com/read/38460252/prognostic-factors-of-tumefactive-demyelinating-lesions-and-differential-features-for-multiple-sclerosis-in-etiology
#10
JOURNAL ARTICLE
Furkan Saridas, Gizem Mesut, Ceren Yayla Ceylan, Rifat Ozpar, Mine Ozsen, Emine Rabia Koc, Sahsine Tolunay, Bahattin Hakyemez, Omer Faruk Turan
BACKGROUND: Many different pathologies may underlie tumefactive demyelinating lesions. Identifying clinical and radiologic distinguishing features before pathologic examination is essential for diagnosis and treatment. In this study, we aimed to determine the clinical and radiologic features affecting the etiology and disease course of patients with tumefactive lesions (TDL). MATERIALS AND METHODS: We included 35 clinicoradiologically or histologically diagnosed TDL patients in our center over 11 years...
March 5, 2024: Multiple Sclerosis and related Disorders
https://read.qxmd.com/read/38457533/clinical-effects-of-a-novel-deep-learning-based-rehabilitation-application-on-cardiopulmonary-function-dynamic-and-static-balance-gait-function-and-activities-of-daily-living-in-adolescents-with-hemiplegic-cerebral-palsy
#11
JOURNAL ARTICLE
Yeongsang An, Seunghwa Min, Chanhee Park
BACKGROUND: Adolescents with hemiplegic cerebral palsy undergo conventional physical therapy (CPT) to improve static and dynamic balance, activities of daily living and cardiopulmonary function. To overcome this problem, we developed an innovative deep learning-based rehabilitation application (DRA) to provide a motivational and chaffed platform for such individuals. DRA evaluates the patients' functional abilities and diagnosis an appropriate therapeutic intervention like CPT. METHODS: We compared the effects of DRA and CPT on 6-minute walking test (6 MWT), Borg rating of perceived exertion scale, Berg balance scale, functional ambulation category, and modified Barthel index in adolescents with hemiplegic cerebral palsy...
March 8, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38456153/combined-repetitive-facilitative-exercise-under-continuous-neuromuscular-electrical-stimulation-and-task-oriented-training-for-hemiplegic-upper-extremity-during-convalescent-phase-after-stroke-before-and-after-feasibility-trial
#12
JOURNAL ARTICLE
Koya Fujimoto, Makoto Ueno, Seiji Etoh, Megumi Shimodozono
INTRODUCTION: Whereas repetitive facilitative exercise (RFE) affects primarily recovery of motor impairment after stroke, task-oriented training (TOT) focuses on facilitating daily use of the affected upper extremity. However, feasibility of combined RFE and TOT has not been reported. We originated "task-oriented RFE," as a new combination therapy for patients with hemiplegic upper extremity after subacute stroke, to examine its feasibility in convalescent rehabilitation wards. METHODS: This is a before-and-after pilot study...
2024: Frontiers in Neurology
https://read.qxmd.com/read/38453749/assessing-risk-of-recurrent-small-bowel-obstruction-after-non-operative-management-in-patients-with-history-of-intra-abdominal-surgery-a-population-based-comprehensive-analysis-in-taiwan
#13
JOURNAL ARTICLE
Shang-Wei Lin, Chung-Yen Chen, Pin-Chun Chen, Che-Lun Feng, Hung-Yu Lin, Jian-Han Chen
BACKGROUND: Despite a significant 30% ten-year readmission rate for SBO patients, investigations into recurrent risk factors after non-operative management are scarce. The study aims to generate a risk factor scoring system, the 'Small Bowel Obstruction Recurrence Score' (SBORS), predicting 6-month recurrence of small bowel obstruction (SBO) after successful non-surgical management in patients who have history of intra-abdominal surgery. METHODS: We analyzed data from patients aged ≥ 18 with a history of intra-abdominal surgery and diagnosed with SBO (ICD-9 code: 560, 568) and were successful treated non-surgically between 2004 and 2008...
March 7, 2024: Surgical Endoscopy
https://read.qxmd.com/read/38450641/pediatric-spastic-wrist-contractures-can-be-well-managed-with-wrist-arthrodesis
#14
JOURNAL ARTICLE
Megan Cain, Paige Lemhouse, Cathleen Buckon, Krister P Freese
BACKGROUND: Severe spastic wrist contractures secondary to cerebral palsy (CP) or alike can have significant implications for patient hand function, hygiene, skin breakdown, and cosmesis. When these contractures become rigid, soft tissue procedures alone are unable to obtain or maintain the desired correction. In these patients' wrist arthrodesis is an option-enabling the hand to be stabilized in a more functional position for hygiene, dressing, and general cosmesis, though are patients satisfied? METHODS: All children who had undergone a wrist arthrodesis for the management of a severe wrist contracture at Shriners Hospital, Portland between January 2016 and January 2021 were identified (n=23)...
March 7, 2024: Journal of Pediatric Orthopedics
https://read.qxmd.com/read/38440394/automatic-rehabilitation-assessment-method-of-upper-limb-motor-function-based-on-posture-and-distribution-force
#15
JOURNAL ARTICLE
Jing Bai, Guocheng Li, Xuanming Lu, Xiulan Wen
The clinical rehabilitation assessment methods for hemiplegic upper limb motor function are often subjective, time-consuming, and non-uniform. This study proposes an automatic rehabilitation assessment method for upper limb motor function based on posture and distributed force measurements. Azure Kinect combined with MediaPipe was used to detect upper limb and hand movements, and the array distributed flexible thin film pressure sensor was employed to measure the distributed force of hand. This allowed for the automated measurement of 30 items within the Fugl-Meyer scale...
2024: Frontiers in Neuroscience
https://read.qxmd.com/read/38440377/feasibility-of-awake-craniotomy-for-brain-arteriovenous-malformations-a-scoping-review
#16
REVIEW
Rabeet Tariq, Umar Ahmed Siddiqui, Mohammad Hamza Bajwa, Ahmer Nasir Baig, Saad Akhtar Khan, Areeba Tariq, Saqib Kamran Bakhshi
BACKGROUND: Brain Arteriovenous Malformations (AVMs) located in proximity to eloquent brain regions are associated with poor surgical outcomes, which may be due to higher rates of postoperative neurological deterioration. Current treatment protocols include stereotactic radiosurgery, transarterial embolization, and surgical resection under general anesthesia. Awake Craniotomy (AC) allows intraoperative mapping of eloquent areas to improve post-operative neurologic outcomes. OBJECTIVES: We reviewed the current literature reporting surgical outcomes and assessed the feasibility of AC for AVM resection...
April 2024: World neurosurgery: X
https://read.qxmd.com/read/38439937/motor-imagery-therapy-improved-upper-limb-motor-function-in-stroke-patients-with-hemiplegia-by-increasing-functional-connectivity-of-sensorimotor-and-cognitive-networks
#17
JOURNAL ARTICLE
Wan Liu, Xinxin Cheng, Jiang Rao, Jiawen Yu, Zhiqiang Lin, Yao Wang, Lulu Wang, Danhui Li, Li Liu, Run Gao
BACKGROUND: Motor imagery therapy (MIT) showed positive effects on upper limbs motor function. However, the mechanism by which MIT improves upper limb motor function is not fully understood. Therefore, our purpose was to investigate the changes in functional connectivity (FC) within and outside the sensorimotor network (SMN) induced by MIT associated with improvement in upper limb motor function in stroke patients. METHODS: A total of 26 hemiplegic stroke patients were randomly divided into MIT ( n = 13) and control ( n = 13) groups...
2024: Frontiers in Human Neuroscience
https://read.qxmd.com/read/38430148/effect-of-mvf-combined-with-fes-on-limb-function-recovery-and-fine-function-rehabilitation-of-hemiplegic-patients-after-aci
#18
JOURNAL ARTICLE
Peng Li, Hui Xin, Xinjie Zhang, Xiuli Li, Lihui Dou, Guiling Wang, Yan Li
BACKGROUND: This study assesses the efficacy of mirror visual feedback (MVF) combined with functional electrical stimulation (FES) in rehabilitating limb function and fine motor skills in hemiplegic patients after acute cerebral infarction (ACI). Given the limited research in this area, this study aims to provide insights into innovative rehabilitation techniques. METHODS: A randomized controlled trial was conducted on 106 post-ACI hemiplegic patients, split into two groups of 53 each...
March 1, 2024: Alternative Therapies in Health and Medicine
https://read.qxmd.com/read/38429890/closed-loop-wearable-device-network-of-intrinsically-controlled-bilateral-coordinated-functional-electrical-stimulation-for-stroke
#19
JOURNAL ARTICLE
Shuxing Xu, Chengyu Li, Conghui Wei, Xinfang Kang, Sheng Shu, Guanlin Liu, Zijie Xu, Mengdi Han, Jun Luo, Wei Tang
Innovative functional electrical stimulation has demonstrated effectiveness in enhancing daily walking and rehabilitating stroke patients with foot drop. However, its lack of precision in stimulating timing, individual adaptivity, and bilateral symmetry, resulted in diminished clinical efficacy. Therefore, a closed-loop wearable device network of intrinsically controlled functional electrical stimulation (CI-FES) system is proposed, which utilizes the personal surface myoelectricity, derived from the intrinsic neuro signal, as the switch to activate/deactivate the stimulation on the affected side...
March 1, 2024: Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
https://read.qxmd.com/read/38424592/resting-state-cortical-electroencephalogram-rhythms-and-network-in-patients-after-chronic-stroke
#20
JOURNAL ARTICLE
Jack Jiaqi Zhang, Zhongfei Bai, Kenneth N K Fong
OBJECTIVE: To investigate the resting-state cortical electroencephalogram (EEG) rhythms and networks in patients with chronic stroke and examine their correlation with motor functions of the hemiplegic upper limb. METHODS: Resting-state EEG data from 22 chronic stroke patients were compared to EEG data from 19 age-matched and 16 younger-age healthy controls. The EEG rhythmic powers and network metrics were analyzed. Upper limb motor functions were evaluated using the Fugl-Meyer assessment-upper extremity scores and action research arm test...
February 29, 2024: Journal of Neuroengineering and Rehabilitation
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