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https://www.readbyqxmd.com/read/29903578/functional-bracing-treatment-for-stable-type-b-ankle-fractures
#1
C van den Berg, T Haak, N L Weil, J M Hoogendoorn
BACKGROUND: In general, stable type B ankle fractures are treated conservatively with cast immobilization or a walking boot during six weeks. Some disadvantages of casting are joint stiffness, muscle wasting and lack of comfort. This study was designed to evaluate whether functional treatment with a removable brace is a safe and more comfortable alternative. MATERIAL AND METHODS: Randomized controlled trial. In the period March 2013 - May 2015, 44 patients visiting the emergency department due to a stable type B ankle fracture were included...
June 4, 2018: Injury
https://www.readbyqxmd.com/read/29902542/topical-epidermal-growth-factor-spray-for-the-treatment-of-chronic-diabetic-foot-ulcers-a-phase-iii-multicenter-double-blind-randomized-placebo-controlled-trial
#2
Kwang Hwan Park, Seung Hwan Han, Joon Pio Hong, Seung-Kyu Han, Doo-Hyung Lee, Bom Soo Kim, Jae Hoon Ahn, Jin Woo Lee
AIMS: This study was conducted to evaluate the efficacy and safety of a novel spray-applied growth factor therapy containing recombinant human epidermal growth factor (rhEGF) for the treatment of chronic diabetic foot ulcers (DFU). METHODS: This study was a phase III double-blind, randomized, placebo-controlled trial. 167 adult patients at six medical centers were randomized to receive routine wound care plus either topical spray treatment with 0.005% rhEGF (n = 82) or an equivalent volume of saline spray (n = 85) twice a day until ulcer healing or for up to 12 weeks...
June 11, 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29898585/outcome-measures-in-the-clinical-evaluation-of-ambulatory-charcot-marie-tooth-1a-subjects
#3
Laura Mori, Valeria Prada, Alessio Signori, Davide Pareyson, Giuseppe Piscosquito, Luca Padua, Costanza Pazzaglia, Gian M Fabrizi, Alessandro Picelli, Angelo Schenone
BACKGROUND: The outcome measures (OMs) in clinical trials for Charcot Marie Tooth disease (CMT) still represent an issue. A recent study highlighted that three additional clinical OMs, the 10 meters walk test (10MWT), 9 hole-peg test, and foot dorsal flexion dynamometry, further improve discrimination between severely and mildly affected patients. Another study recently assess the validity and reliability of the 6 Minutes Walking test (6MWT). AIM: To identify the most useful scales in the clinical evaluation of CMT1A patients...
June 11, 2018: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/29882738/effects-of-low-power-light-therapy-on-the-tissue-repair-process-of-chronic-wounds-in-diabetic-feet
#4
Joelita de Alencar Fonseca Santos, Mariana Barbosa Dias Campelo, Rauirys Alencar de Oliveira, Renata Amadei Nicolau, Verônica Elis Araújo Rezende, Emilia Ângela Loschiavo Arisawa
OBJECTIVE: To analyze the efficacy of the therapeutic use of Low-Level Laser Therapy (LLLT) on the tissue repair process of chronic wounds in patients with diabetic feet through the analysis of Pressure Ulcer Scale for Healing (PUSH) scales, pain and the measurement done using the ImageJ© software. METHODS: This clinical trial was carried out with 18 patients 30-59 years of age, who had chronic wounds on their foot due to complications of diabetes mellitus. The patients were randomly allocated in two different groups of equal numbers: Control and Laser Groups...
June 2018: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/29879593/effect-of-debridement-of-plantar-hyperkeratoses-on-gait-in-older-people-an-exploratory-trial
#5
Caleb Araguas Garcia, Francisco Corbi Soler
Hyperkeratoses are a common cause of foot pain due to the release of inflammatory mediators, which can have an impact on the mobility and independence of people suffering from them. However, the repercussions that hyperkeratoses have on gait parameters remain uncertain. AIM: The aim of this study is to analyze the repercussions that plantar hyperkeratosis debridement has on several kinematic and kinetic variables of gait in a group of older participants. METHODS: 98 older participants (75...
May 31, 2018: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/29869014/minimally-invasive-versus-open-chevron-osteotomy-for-hallux-valgus-correction-a-randomized-controlled-trial
#6
Gerhard Kaufmann, Dietmar Dammerer, Felix Heyenbrock, Matthias Braito, Lorenz Moertlbauer, Michael Liebensteiner
PURPOSE: The purpose of this study was to compare a minimally invasive chevron osteotomy technique (MIS group) and the well-established open chevron technique (OC group) for correction of hallux valgus deformity. METHODS: Patients who were scheduled to undergo a hallux valgus surgery by means of a distal chevron osteotomy were randomly assigned to one of the two groups. Pre-operatively, six weeks, 12 weeks, and nine months post-operatively the following outcome parameters were determined: Visual Analog Scores (VAS) of pain, the American Orthopedic Foot and Ankle Society (AOFAS) forefoot score, radiographic outcome measures, range of motion (ROM), and patient satisfaction...
June 4, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29867384/the-alteration-of-emotion-regulation-precedes-the-deficits-in-interval-timing-in-the-bachd-rat-model-for-huntington-disease
#7
Daniel Garces, Nicole El Massioui, Charlotte Lamirault, Olaf Riess, Huu P Nguyen, Bruce L Brown, Valérie Doyère
Huntington disease (HD) is an autosomal dominantly inherited, progressive neurodegenerative disorder which is accompanied by executive dysfunctions and emotional alteration. The aim of the present study was to assess the impact of emotion/stress on on-going highly demanding cognitive tasks, i.e., temporal processing, as a function of age in BACHD rats (a "full length" model of HD). Middle-aged (4-6 months) and old (10-12 months) rats were first trained on a 2 vs. 8-s temporal discrimination task, and then exposed to a series of bisection tests under normal and stressful (10 mild unpredictable foot-shocks) conditions...
2018: Frontiers in Integrative Neuroscience
https://www.readbyqxmd.com/read/29865941/comparison-of-ankle-foot-orthoses-with-plantar-flexion-stop-and-plantar-flexion-resistance-in-the-gait-of-stroke-patients-a-randomized-controlled-trial
#8
Sumiko Yamamoto, Souji Tanaka, Naoyuki Motojima
BACKGROUND: The effect of plantar flexion resistance of ankle-foot orthoses on the ankle and knee joints is well known, but its effect on the hip joint and upper body movement during the gait of stroke patients remains unclear. OBJECTIVES: To compare the effect of an ankle-foot orthosis with plantar flexion stop and an ankle-foot orthosis with plantar flexion resistance on the gait of stroke patients in the subacute phase. STUDY DESIGN: Randomized controlled trial...
May 1, 2018: Prosthetics and Orthotics International
https://www.readbyqxmd.com/read/29847387/readiness-for-discharge-after-foot-and-ankle-surgery-using-peripheral-nerve-blocks-a-randomized-controlled-trial-comparing-spinal-and-general-anesthesia-as-supplements-to-nerve-blocks
#9
Jacques T YaDeau, Kara G Fields, Richard L Kahn, Vincent R LaSala, Scott J Ellis, David S Levine, Leonardo Paroli, Thuyvan H Luu, Matthew M Roberts
BACKGROUND: Neuraxial anesthesia is often viewed as superior to general anesthesia but may delay discharge. Comparisons do not typically use multimodal analgesics and nerve blockade. Combining nerve blockade with general anesthesia may reduce pain, opioid consumption, and nausea. We hypothesized that general anesthesia (with nerve blocks) would lead to earlier readiness for discharge, compared to spinal anesthesia (with nerve blocks). METHODS: All patients underwent ambulatory foot and ankle surgery, with a predicted case duration of 1-3 hours...
May 25, 2018: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29846832/a-randomized-controlled-trial-comparing-helium-neon-laser-therapy-and-infrared-laser-therapy-in-patients-with-diabetic-foot-ulcer
#10
Sayed A Tantawy, Walid K Abdelbasset, Dalia M Kamel, Saud M Alrawaili
This study aimed to compare the effects of (HNLT) and (ILT) on diabetic foot ulcer. Sixty-five patients with diabetic foot ulcer (51 males and 14 females) aged 50-60 years. The participants were classified randomly to two groups, groups I and II. Group I received helium-neon laser therapy (HNLT) and conventional therapy with and group II received infrared laser therapy (ILT) and conventional therapy with for 8 weeks. Ulcer surface area was assessed using a sheet of cellophane paper at the beginning of the study, after 4 weeks, and after 8 weeks at the end of the study...
May 30, 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29806355/-research-progress-of-dipeptidyl-peptidase-4-inhibitors-on-healing-of-chronic-diabetic-foot-ulcers
#11
REVIEW
Yunyi Gao, Yujie Liang, Xingwu Ran
Objective: To review the effect of dipeptidyl peptidase 4 (DPP-4) inhibitors on the wound healing and its mechanisms in chronic diabetic foot ulcers. Methods: The latest literature concerning DPP-4 inhibitors for chronic diabetic foot ulcers was extensively reviewed, as well as the potential benefit and mechanism of DPP-4 inhibitors on wound healing of diabetic foot ulcers was analyzed thoroughly. Results: DPP-4 inhibitors can accelerated the ulcer healing...
May 1, 2018: Chinese Journal of Reparative and Reconstructive Surgery
https://www.readbyqxmd.com/read/29802042/prognostic-value-of-the-society-for-vascular-surgery-wound-ischemia-and-foot-infection-wifi-classification-in-patients-with-no-option-chronic-limb-threatening-ischemia
#12
Steven T W van Haelst, Martin Teraa, Frans L Moll, Gert J de Borst, Marianne C Verhaar, Michael S Conte
OBJECTIVE: The Wound, Ischemia, and foot Infection (WIfI) classification was developed to assess amputation risk and hence to aid in clinical decision-making in patients with chronic limb-threatening ischemia (CLTI). WIfI has been validated in multiple CLTI cohorts worldwide. In this study, we examined the relationship between WIfI stage and clinical outcomes in a well-defined subpopulation of CLTI patients considered not eligible for conventional revascularization. The aim of this study was to assess the prognostic value of the WIfI classification for clinical outcomes in a "no-option" CLTI population...
May 22, 2018: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29798583/-effectiveness-analysis-of-ilizarov-external-fixation-and-ankle-arthrodesis-in-treatment-of-late-traumatic-ankle-arthritis
#13
Jun Li, Zeyu Huang, Yue Fang, Fuguo Huang, Lei Liu
Objective: To evaluate the effectiveness of Ilizarov external fixation and ankle arthrodesis in the treatment of late traumatic ankle arthritis. Methods: Between June 2013 and June 2015, 27 patients with late traumatic ankle arthritis were treated with Ilizarov external fixation technique. There were 16 males and 11 females with an age of 27-69 years (mean, 45.7 years). Sixteen cases were on the left side, 11 on the right side. All the patients suffered from traumatic ankle fractures or ligament damages caused by initial traumas...
November 1, 2017: Chinese Journal of Reparative and Reconstructive Surgery
https://www.readbyqxmd.com/read/29798536/-research-progress-of-three-dimensional-printing-technique-in-foot-and-ankle-surgery
#14
REVIEW
Daiqing Wei, Cui Li, Yangbo Xu
Objective: To review the current research progress of three-dimensional (3-D) printing technique in foot and ankle surgery. Methods: Recent literature associated with the clinical application of 3-D printing technique in the field of medicine, especially in foot and ankle surgery was reviewed, summarized, and analyzed. Results: At present, 3-D printing technique has been applied in foot and ankle fracture, segmental bone defect, orthosis, corrective surgery, reparative and reconstructive surgery which showed satisfactory effectiveness...
August 1, 2017: Chinese Journal of Reparative and Reconstructive Surgery
https://www.readbyqxmd.com/read/29785265/a-randomized-controlled-trial-of-the-safety-and-efficacy-of-a-topical-gentamicin-collagen-sponge-in-diabetic-patients-with-a-mild-foot-ulcer-infection
#15
Ilker Uçkay, Benjamin Kressmann, Sébastien Di Tommaso, Marina Portela, Heba Alwan, Hubert Vuagnat, Sophie Maître, Christophe Paoli, Benjamin A Lipsky
Objectives: The initial phase of infection of a foot ulcer in a person with diabetes is often categorized as mild. Clinicians usually treat these infections with antimicrobial therapy, often applied topically. Some experts, however, believe that mild diabetic foot ulcer infections will usually heal with local wound care alone, without antimicrobial therapy or dressings. Methods: To evaluate the potential benefit of treatment with a topical antibiotic, we performed a single-center, investigator-blinded pilot study, randomizing (1:1) adult patients with a mild diabetic foot ulcer infection to treatment with a gentamicin-collagen sponge with local care versus local care alone...
2018: SAGE Open Medicine
https://www.readbyqxmd.com/read/29778980/the-influence-of-early-or-delayed-provision-of-ankle-foot-orthoses-on-pelvis-hip-and-knee-kinematics-in-patients-with-sub-acute-stroke-a-randomized-controlled-trial
#16
Corien D M Nikamp, Job van der Palen, Hermie J Hermens, Johan S Rietman, Jaap H Buurke
BACKGROUND: Compensatory pelvis, hip- and knee movements are reported after stroke to overcome insufficient foot-clearance. Ankle-foot orthoses (AFOs) are often used to improve foot-clearance, but the optimal timing of AFO-provision post-stroke is unknown. Early AFO-provision to prevent foot-drop might decrease the development of compensatory movements, but it is unknown whether timing of AFO-provision affects post-stroke kinematics. RESEARCH QUESTIONS: 1) To compare the effect of AFO-provision at two different points in time (early versus delayed) on frontal pelvis and hip, and sagittal hip and knee kinematics in patients with sub-acute stroke...
May 16, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29775166/aluminum-foot-insoles-reduce-plantar-forefoot-pressure-and-increase-foot-comfort-for-motorcyclists
#17
Israel Casado-Hernández, Ricardo Becerro-de-Bengoa-Vallejo, Daniel López-López, Antonio Gómez-Bernal, Marta Elena Losa-Iglesias
BACKGROUND: Foot pain and paresthesia are common in cycling, due to plantar pressure and repetitive loading. OBJECTIVES: The aim was to investigate the effect of foot insoles on plantar pressure of the foot in motorcycling, as well as self-reported comfort. STUDY DESIGN: A randomized crossover clinical trial. METHODS: A flexible foot pressure mat (GP MobilData WiFi® Gebiomized®) with different sizes was utilized. RESULTS: Maximum pressure values occurred predominantly in the hallux with 4...
May 1, 2018: Prosthetics and Orthotics International
https://www.readbyqxmd.com/read/29773516/lymphoedema-management-to-prevent-acute-dermatolymphangioadenitis-in-podoconiosis-in-northern-ethiopia-golbet-a-pragmatic-randomised-controlled-trial
#18
Henok Negussie, Meseret Molla, Moses Ngari, James A Berkley, Esther Kivaya, Patricia Njuguna, Greg Fegan, Abreham Tamiru, Abebe Kelemework, Trudie Lang, Melanie J Newport, Andy McKay, Fikre Enquoselassie, Gail Davey
BACKGROUND: Podoconiosis (also known as endemic, non-filarial elephantiasis) affects about 4 million subsistence farmers in tropical Africa. Poor awareness of the condition and inadequate evidence for the efficacy of treatment mean that no government in an endemic country yet offers lymphoedema management for patients with podoconiosis. Among patients with filarial lymphoedema, trials suggest that limb care is effective in reducing the most disabling sequelae: episodes of acute dermatolymphangioadenitis...
May 14, 2018: Lancet Global Health
https://www.readbyqxmd.com/read/29771148/prospective-randomized-trial-of-electrolysis-for-chronic-plantar-heel-pain
#19
Tomás Fernández-Rodríguez, Álvaro Fernández-Rolle, Sebastián Truyols-Domínguez, Jose C Benítez-Martínez, Jose Casaña-Granell
BACKGROUND: Chronic plantar heel pain (CPHP) is a common condition with high prevalence rates and a projected cost of treatment of US$192 to US$376 million. There are several therapeutic approaches and there is increased interest in treatments aimed at the regeneration of tissues with poor healing potential. Our purpose was to investigate the effectiveness of ultrasound-guided percutaneous needle electrolysis in chronic plantar heel pain. METHODS: A total of 73 patients with a clinical and ultrasonographic diagnosis of plantar heel pain unrelated to systemic inflammatory disease who had not received any other treatment in the previous 6 months on the affected foot were randomly allocated to receive either ultrasound-guided percutaneous needle electrolysis of the fascia (experimental group, n = 39) or placebo puncture (control group, n = 34)...
May 1, 2018: Foot & Ankle International
https://www.readbyqxmd.com/read/29768332/short-term-effects-of-customized-arch-support-insoles-on-symptomatic-flexible-flatfoot-in-children-a-randomized-controlled-trial
#20
RANDOMIZED CONTROLLED TRIAL
Ru-Lan Hsieh, Hui-Ling Peng, Wen-Chung Lee
BACKGROUND: Limited evidence is available regarding the effects of insoles on pediatric flexible flatfoot because of the heterogeneity and low methodological quality of previous studies. The purpose of this prospective trial is to examine the short-term effects of customized arch support insoles on symptomatic flexible flatfoot in children by using the International Classification of Functioning, randomized controlled Disability, and Health (ICF) framework. METHODS: This study was conducted in a rehabilitation outpatient clinic of a teaching hospital...
May 2018: Medicine (Baltimore)
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