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https://www.readbyqxmd.com/read/28938775/effects-of-different-types-of-dark-brooders-on-injurious-pecking-damage-and-production-related-traits-at-rear-and-lay-in-layers
#1
A B Riber, D A Guzman
Injurious pecking (IP) remains one of the major welfare challenges in housing of laying hens worldwide due to the negative consequences it inflicts on animal welfare and economy. One potential solution to reduce IP is the use of dark brooders as the primary heat source during rearing. The objective was to investigate effects of rearing layer chicks with different management strategies and size allowances of dark brooders on IP and production-related traits during rear and lay. Groups of 100 to 103 Isa Warren chicks were reared either with one of 4 brooder types (n = 4 per treatment) or with whole-house heating (control: n = 6)...
October 1, 2017: Poultry Science
https://www.readbyqxmd.com/read/28938570/pd-l1-expression-as-poor-prognostic-factor-in-patients-with-non-squamous-non-small-cell-lung-cancer
#2
Cuiling Zhou, Jianjun Tang, Huanhuan Sun, Xiaobin Zheng, Zhanyu Li, Tiantian Sun, Jie Li, Shuncong Wang, Xiuling Zhou, Hongliu Sun, Zhibin Cheng, Hongyu Zhang, Haiqing Ma
OBJECTIVES: The role of programmed cell death ligand 1 (PD-L1) in non-small cell lung cancer (NSCLC), especially according to histologic type, remains controversial. The purpose of this study was to assess PD-L1 expression and its association with overall survival (OS) and clinicopathologic characteristics in NSCLC. MATERIALS AND METHODS: Formalin-fixed paraffin-embedded specimens were obtained from 108 patients with surgically resected primary NSCLC. PD-L1 expression was assessed via immunohistochemistry using a histochemistry score system...
August 29, 2017: Oncotarget
https://www.readbyqxmd.com/read/28938519/gilaburu-viburnum-opulus-l-fruit-extract-alleviates-testis-and-sperm-damages-induced-by-taxane-based-chemotherapeutics
#3
Serpil Sarıözkan, Gaffari Türk, Ayşe Eken, Latife Çakır Bayram, Ayşe Baldemir, Gülden Doğan
In this study, it was aimed to investigate the possible protective effects of gilaburu (Viburnum opulus L., Glb) fruit extract on testis and sperm damages induced by docetaxel (DTX) and paclitaxel (PTX) chemotherapeutics in rats. Sixty adult male Wistar albino rats were divided into 6 equal groups, 10 animals each. The groups were created as control (weekly i.p. saline injection), Glb (weekly i.p. saline injection and daily oral 100mg/kg Glb), DTX (weekly i.p. injection of 5mg/kg DTX), PTX (weekly i.p. injection of 4mg/kg PTX), DTX+Glb (weekly i...
September 18, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28938239/absence-of-a-correlation-between-the-abo-blood-group-and-thrombus-burden-in-patients-with-st-segment-elevation-myocardial-infarction
#4
Lutfu Askin, Mustafa Cetin, Serdar Turkmen
OBJECTIVE: ABO antigens are highly abundant in many human cell types, including platelets, vascular endothelium, and red blood cells. The presence of a thrombus is associated with adverse clinical outcomes in patients with ST-segment elevation myocardial infarction (STEMI). We reviewed the relationship between ABO blood groups and thrombus burden in patients with STEMI. PATIENTS AND METHODS: We carried out a retrospective study of 396 patients with STEMI who did not have an ABO blood group or thrombus burden...
September 21, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28937923/psychological-factors-in-chronic-edema-a-case-control-study
#5
Christine J Moffatt, Aimee Aubeeluck, Peter J Franks, Debra C Doherty, Peter Mortimer, Isabelle Quere
BACKGROUND: To examine psychological health and perceived social support in patients with chronic edema (CE). METHODS AND RESULTS: A random sample of 107 patients with CE was group matched for age and gender with 102 community controls. The cases had swelling of the arm (38%) and leg (61%) and midline swelling (14%). Cases were more likely to be single or divorced/separated (p = 0.041) and have reduced mobility (p < 0.001). They had significantly poorer overall health related quality of life (HRQoL), in particular physical functioning (p = 0...
September 2017: Lymphatic Research and Biology
https://www.readbyqxmd.com/read/28937860/association-of-adamts4-and-adamts9-levels-with-cardiovascular-risk-in-patients-with-primary-hyperparathyroidism
#6
Melia Karakose, Mustafa Caliskan, Muyesser Sayki Arslan, Taner Demirci, Suleyman Karakose, Esra Tutal, Erman Cakal
PURPOSE: Primary hyperparathyroidism (PHPT) has been associated with increased incidence of morbidity and mortality of the cardiovascular system. The pathogenetic mechanisms underlying this association are still not completely clear. A disintegrin and metalloproteinase with thrombospondin-like motifs (ADAMTS) play a critical role in atherosclerosis. This study aimed to investigate the levels of ADAMTS4 and ADAMTS9 and relationship between these proteoglycanases and cardiometabolic abnormalities in PHPT...
September 22, 2017: Endocrine Research
https://www.readbyqxmd.com/read/28937831/impact-of-smoking-on-the-ocular-surface-tear-function-and-tear-osmolarity
#7
Serdar Aktaş, Mehmet Tetikoğlu, Ahmet Koçak, Metin Kocacan, Hatice Aktaş, Hacı Murat Sağdık, Fatih Özcura
PURPOSE: This study evaluated the effects of cigarette smoking on the ocular surface, tear function, and tear osmolarity. MATERIALS AND METHODS: A total of 50 smokers with at least 5 years of heavy smoking (defined as 1 pack/day) and 51 nonsmoking, healthy individuals were enrolled. Tear osmolarity was measured with an osmometer (TearLab(™) Osmolarity System). Ocular surface examinations involved corneal fluorescein staining, measurement of the tear film breakup time (TBUT), the Schirmer 1 test, measurement of corneal sensitivity with a Cochet-Bonnet esthesiometer, and conjunctival impression cytology...
September 22, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28937803/hip-arthroscopy-for-femoroacetabular-impingement-in-a-military-population
#8
Darren D Thomas, Andrew S Bernhardson, Ethan Bernstein, Christopher B Dewing
BACKGROUND: Femoroacetabular impingement (FAI) can lead to hip pain and early joint degeneration. There have been few reports to date on the outcomes of hip arthroscopy for the treatment of FAI in the military population. Purpose/Hypothesis: The purpose of this study was to compare patient demographics with postoperative outcomes after hip arthroscopy for symptomatic FAI and to identify preoperative risk factors for poor outcomes. The hypothesis was that certain preoperative patient characteristics will be predictive of poorer outcomes and that lower outcomes scores will be associated with a higher likelihood of medical separation from the military...
September 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28937500/serum-adiponectin-levels-in-patients-with-systemic-lupus-erythematosus-a-meta-analysis
#9
Ahmed Ali Dini, Peng Wang, Dong-Qing Ye
BACKGROUND: Higher serum adiponectin in systemic lupus erythematosus (SLE) patients mitigates the inflammatory response. Previous studies investigated serum adiponectin level in SLE patients compared with control subjects, yielding inconsistent results. OBJECTIVE: The aim of this meta-analysis was to assess the difference between serum adiponectin levels in SLE patients compared with control subjects. METHODS: MEDLINE, PubMed, EMBASE, and Web of Science were searched from inception to August 31, 2016, to identify all observational studies that examined the relationship between serum adiponectin levels and SLE...
September 21, 2017: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/28937490/the-relationship-between-body-mass-index-and-fatty-infiltration-in-the-shoulder-musculature
#10
David F Dow, Kaushal Mehta, Yuanfang Xu, Eric England
OBJECTIVE: Fatty infiltration in the rotator cuff muscles has been well studied in the setting of rotator cuff tendon tears to help predict outcomes of surgical repair. Fatty infiltration in the rotator cuff has also been independently correlated to the variables of age and sex. The purpose of our study was to determine if there is a relationship between body mass index and fatty infiltration in patients with no imaging evidence of rotator cuff tendinosis or tear. METHODS: Radiology reports of all magnetic resonance imaging examinations of the shoulder were searched over a 2-year period...
September 20, 2017: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/28937471/serum-adiponectin-levels-in-patients-with-systemic-lupus-erythematosus-a-meta-analysis
#11
Ahmed Ali Dini, Peng Wang, Dong-Qing Ye
BACKGROUND: Higher serum adiponectin in systemic lupus erythematosus (SLE) patients mitigates the inflammatory response. Previous studies investigated serum adiponectin level in SLE patients compared with control subjects, yielding inconsistent results. OBJECTIVE: The aim of this meta-analysis was to assess the difference between serum adiponectin levels in SLE patients compared with control subjects. METHODS: MEDLINE, PubMed, EMBASE, and Web of Science were searched from inception to August 31, 2016, to identify all observational studies that examined the relationship between serum adiponectin levels and SLE...
October 2017: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/28937460/utility-of-the-surgical-apgar-score-for-patients-who-undergo-surgery-for-spinal-metastasis
#12
Darryl Lau, Timothy J Yee, Frank La Marca, Rakesh Patel, Paul Park
STUDY DESIGN: Retrospective review of patients who underwent surgery for spinal metastasis between 2005 and 2011. OBJECTIVE: To assess the utility of the surgical Apgar score (SAS) in patients who underwent surgery for spinal metastasis. SUMMARY OF BACKGROUND DATA: Surgery for spinal metastasis can be associated with relatively high morbidity and mortality. Consequently, identifying patients at risk for major postoperative complications is important...
October 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28937455/palliative-surgery-for-spinal-metastases-using-posterior-decompression-and-fixation-combined-with-intraoperative-vertebroplasty
#13
Liang Dong, Mingsheng Tan, Di Wu, Ping Yi, Feng Yang, Xiangsheng Tang, Qingying Hao
STUDY DESIGN: Retrospective study. OBJECTIVE: To evaluate the clinical outcome of palliative surgery using posterior decompression and fixation combined with intraoperative vertebroplasty (PDFIV) for the treatment of spinal metastases, and analyze the indications for PDFIV using a neurological, oncologic, mechanical, and systemic framework. SUMMARY OF BACKGROUND DATA: Palliative surgery is widely used to spinal metastatic patients with poor condition for enough postoperative recovery...
October 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28937454/life-expectancy-and-metastatic-spine-scoring-systems-an-academic-institutional-experience
#14
Brian T Ragel, Gustavo A Mendez, Justin Reddington, David Ferachi, Charlotte D Kubicky, Travis C Philipp, Natalie L Zusman, Paul Klimo, Robert Hart, Jung Yoo, Alex C Ching
STUDY DESIGN: A retrospective data collection study with application of metastatic spine scoring systems. OBJECTIVES: To apply the Tomita and revised Tokuhashi scoring systems to a surgical cohort at a single academic institution and analyze spine-related surgical morbidity and mortality rates. SUMMARY OF BACKGROUND DATA: Surgical management of metastatic spine patients requires tools that can accurately predict patient survival, as well as knowledge of morbidity and mortality rates...
October 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28937409/development-and-feasibility-of-self-management-application-in-left-ventricular-assist-devices
#15
Jesus M Casida, James E Aikens, Heidi Craddock, Matthew W Aldrich, Francis D Pagani
Despite major advancements in mechanical circulatory support, the self-management (SM) for patients with a left-ventricular assist device (LVAD) remains complex and challenging for patients and their caregivers. We have developed a mobile phone application (VAD Care App) to organize and simplify the LVAD SM process. This article describes the development and feasibility study of the app as an SM tool for LVAD patients and caregivers requiring support from ventricular assist device (VAD) coordinators. The specific aim was to evaluate the app's acceptability and usability and the users' competency...
September 20, 2017: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/28937334/optimal-threshold-estimator-of-a-prognostic-marker-by-maximizing-a-time-dependent-expected-utility-function-for-a-patient-centered-stratified-medicine
#16
Etienne Dantan, Yohann Foucher, Marine Lorent, Magali Giral, Philippe Tessier
Defining thresholds of prognostic markers is essential for stratified medicine. Such thresholds are mostly estimated from purely statistical measures regardless of patient preferences potentially leading to unacceptable medical decisions. Quality-Adjusted Life-Years are a widely used preferences-based measure of health outcomes. We develop a time-dependent Quality-Adjusted Life-Years-based expected utility function for censored data that should be maximized to estimate an optimal threshold. We performed a simulation study to compare estimated thresholds when using the proposed expected utility approach and purely statistical estimators...
October 20, 2016: Statistical Methods in Medical Research
https://www.readbyqxmd.com/read/28937069/oral-health-in-diabetic-and-nondiabetic-patients-with-chronic-kidney-disease
#17
Lingam Amara Swapna, Pradeep Koppolu, Jyothi Prince
The objective of our study is to assess the subjective and objective oral manifestations and salivary pH in diabetic and nondiabetic uremic patients at a nephrology clinic. A total of 194 diabetic and nondiabetic patients with chronic kidney disease (CKD), who were divided into four groups, Group A, B, C, D, and who were attending a nephrology clinic were included in the study. Predialytic unstimulated whole salivary pH was recorded using pH- measuring strips. Subjective and objective findings were evaluated and recorded in the specially designed pro forma...
September 2017: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/28937065/mycophenolate-mofetil-or-cyclophosphamide-in-indian-patients-with-lupus-nephritis-which-is-better-a-single-center-experience
#18
Satish Mendonca, Devika Gupta, Sofia Ali, Pooja Gupta
Mycophenolate mofetil (MMF) is used extensively for the induction therapy of lupus nephritis (LN) and has even outpaced intravenous (i.v.) cyclophosphamide (CyP) as the initial choice of therapy. There are no studies comparing the response of MMF with standard dose i.v. CyP in Indian patients with LN. We conducted a 24-week prospective, randomized, open-label trial comparing oral MMF with monthly i.v. CyP as induction therapy for active biopsy proven Class III and IV LN. The primary end-point was response to treatment at 24 weeks, and the secondary end-points were complete remission, Systemic Lupus Erythematosus Disease Activity Index scores (SLEDAI) and adverse reactions...
September 2017: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/28937043/inhibition-of-cd38-cyclic-adp-ribose-pathway-protects-rats-against-ropivacaine-induced-convulsion
#19
Yu Zou, Xin He, Qian-Yi Peng, Qu-Lian Guo
BACKGROUND: The CD38/cyclic ADP-ribose (cADPR) pathway plays a role in various central nervous system diseases and in morphine tolerance, but its role in local anesthetic intoxication is unknown. The aim of this study was to determine the role of the CD38/cADPR pathway in ropivacaine-induced convulsion. METHODS: Forty male Sprague-Dawley rats were randomly divided into five groups (n = 8 per group): sham group, ropivacaine group, ropivacaine+8-Br-cADPR (5 nmol) group, ropivacaine+8-Br-cADPR (10 nmol) group, and ropivacaine+8-Br-cADPR (20 nmol) group (no rats died)...
October 5, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28937040/surgical-outcomes-of-anomalous-origin-of-the-left-coronary-artery-from-the-pulmonary-artery-in-children-an-echocardiography-follow-up
#20
Yan Gao, Jing Zhang, Guo-Ying Huang, Xue-Cun Liang, Bing Jia, Xiao-Jing Ma
BACKGROUND: Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) is a rare but potentially life-threatening congenital heart defect. A retrospective analysis was carried out to elucidate the surgical outcomes of ALCAPA in infants and children using follow-up echocardiography. METHODS: From September 2008 to March 2017, 26 children diagnosed with ALCAPA underwent left coronary re-implantation. All surviving patients received echocardiography during follow-up...
October 5, 2017: Chinese Medical Journal
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