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https://www.readbyqxmd.com/read/29215900/apoe-e4-genotype-and-lifestyle-interaction-on-cognitive-performance-results-of-the-life-adult-study
#1
Francisca S Rodriguez, Matthias L Schroeter, Katrin Arélin, A Veronica Witte, Ronny Baber, Ralph Burkhardt, Christoph Engel, Markus Löffler, Joachim Thiery, Arno Villringer, Tobias Luck, Steffi G Riedel-Heller
OBJECTIVE: Previous studies have shown that the e4-allele of the APOE gene is associated with a higher risk of developing dementia. Our study investigated whether well-known associations between lifestyle factors and cognitive functioning may be stronger in individuals who carry the dementia risk variant of the APOE gene and whether this association is amplified with older age. METHOD: Data analysis comprised 7,526 participants (aged 40- to 79-years-old) from the population-based LIFE-Adult-study...
December 7, 2017: Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association
https://www.readbyqxmd.com/read/29213506/symptoms-of-depression-in-patients-with-mild-cognitive-impairment-in-parkinson-s-disease
#2
Ana Lara Soares Blum Malak, Luiz Felipe Vasconcellos, João Santos Pereira, Denise Vieira Greca, Manuela Cruz, Heloisa Veiga Dias Alves, Mariana Sptiz, Helenice Charchat-Fichman
Objective: To investigate the most frequent depressive symptoms and their association with cognition in Parkinson's disease (PD) patients with mild cognitive impairment (MCI). Methods: 48 patients with PD and 44 controls (CG), aged between 50 and 80 years and with at least 4 years of formal education, all with MCI and none diagnosed with depression, were assessed. Patients and controls were matched for age, education, and Mini-Mental State Examination (MMSE) score...
April 2017: Dementia & Neuropsychologia
https://www.readbyqxmd.com/read/29209876/mentalization-deficit-in-bipolar-patients-during-an-acute-depressive-and-manic-episode-association-with-cognitive-functions
#3
Anna Bodnar, Janusz K Rybakowski
BACKGROUND: A number of studies in bipolar patients have shown a deficit in mentalization (theory of mind), one of the main aspects of social cognition. The aim of current study was to assess both cognitive and affective mentalization in well-defined groups of depressed and manic bipolar patients, compared to healthy control subjects, using a battery of tests measuring mentalization processes. The second aim was to investigate a possible relationship between cognitive and affective mentalization and cognitive functions in bipolar patients during a depressive and manic episode...
December 6, 2017: International Journal of Bipolar Disorders
https://www.readbyqxmd.com/read/29209781/age-dependent-cognitive-dysfunction-in-untreated-hereditary-transthyretin-amyloidosis
#4
Ana Martins da Silva, Sara Cavaco, Joana Fernandes, Raquel Samões, Cristina Alves, Márcio Cardoso, Jeffery W Kelly, Cecília Monteiro, Teresa Coelho
Central nervous system (CNS) involvement in hereditary transthyretin (TTR) amyloidosis has been described in patients whose disease course was modified by liver transplant. However, cognitive dysfunction has yet to be investigated in those patients. Moreover, CNS involvement in untreated patients or asymptomatic mutation carriers remains to be studied. A series of 340 carriers of the TTRVal30Met mutation (180 symptomatic and 160 asymptomatic) underwent a neuropsychological assessment, which included the Dementia Rating Scale-2 (DRS-2), auditory verbal learning test, semantic fluency, phonemic fluency, and trail making test...
December 5, 2017: Journal of Neurology
https://www.readbyqxmd.com/read/29201811/the-characteristics-of-cognitive-impairment-and-their-effects-on-functional-outcome-after-inpatient-rehabilitation-in-subacute-stroke-patients
#5
Soo Ho Park, Min Kyun Sohn, Sungju Jee, Shin Seung Yang
Objective: To determine the frequency and characteristics of vascular cognitive impairment (VCI) in patients with subacute stroke who underwent inpatient rehabilitation and to analyze whether cognitive function can predict functional assessments after rehabilitation. Methods: We retrospectively reviewed the medical records of patients who were admitted to our rehabilitation center after experiencing a stroke between October 2014 and September 2015. We analyzed the data from 104 patients who completed neuropsychological assessments within 3 months after onset of a stroke...
October 2017: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/29200836/computerized-cognitive-stimulation-and-engagement-programs-in-older-adults-with-mild-cognitive-impairment-comparing-feasibility-acceptability-and-cognitive-and-psychosocial-effects
#6
Leila Djabelkhir, Ya-Huei Wu, Jean-Sébastien Vidal, Victoria Cristancho-Lacroix, Fabienne Marlats, Hermine Lenoir, Ariela Carno, Anne-Sophie Rigaud
Purpose: Mild cognitive impairment (MCI) is associated with a higher risk of dementia and is becoming a topic of interest for pharmacological and nonpharmacological interventions. With advances in technology, computer-based cognitive exercises are increasingly integrated into traditional cognitive interventions, such as cognitive training. Another type of cognitive intervention involving technology use is cognitive engagement, consisting of involving participants in highly motivational and mentally challenging activities, such as learning to use a form of new digital technology...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29198217/what-does-it-take-to-search-organized-the-cognitive-correlates-of-search-organization-during-cancellation-after-stroke
#7
Antonia F Ten Brink, Johanna M A Visser-Meily, Tanja C W Nijboer
OBJECTIVES: Stroke could lead to deficits in organization of visual search. Cancellation tests are frequently used in standard neuropsychological assessment and appear suitable to measure search organization. The current aim was to evaluate which cognitive functions are associated with cancellation organization measures after stroke. METHODS: Stroke patients admitted to inpatient rehabilitation were included in this retrospective study. We performed exploratory factor analyses to explore cognitive domains...
December 4, 2017: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/29190120/texas-mexican-american-adult-normative-studies-normative-data-for-commonly-used-clinical-neuropsychological-measures-for-english-and-spanish-speakers
#8
Sid E O'Bryant, Melissa Edwards, Leigh Johnson, James Hall, Adriana Gamboa, Judith O'jile
This study aimed to provide normative references for Mexican Americans on neuropsychological measures of cognitive functioning. Data were analyzed from a total of 797 Mexican-Americans recruited across three Texas-based studies with approximately one-half of the participants tested in Spanish. Normative tables include: MMSE, AMNART, WMS-III (Logical Memory I, II; Visual Reproduction I, II; Digit Span), CERAD, RAVLT, Exit25, CLOX 1 & 2, Trail Making Test- A&B, BNT, COWA, and Animal Naming. The norms were stratified by education then age...
November 30, 2017: Developmental Neuropsychology
https://www.readbyqxmd.com/read/29188884/model-construction-for-biological-age-based-on-a-cross-sectional-study-of-a-healthy-chinese-han-population
#9
W Zhang, L Jia, G Cai, F Shao, H Lin, Z Liu, F Liu, D Zhao, Z Li, X Bai, Z Feng, X Sun, X Chen
OBJECTIVES: Biological age (BA) has been proposed to evaluate the aging status in an objective way instead of chronological age (CA). The purpose of our study is to construct a more precise formula of BA in the cross-sectional study based on a largest-ever sample of our studies. This formula aims at better evaluation of body function and exploring the disciplines of aging in different genders and age stages. METHODS: A total of 1,373 healthy Chinese Han (age range, 19-93 years) were recruited from five cities in China, including 581 males and 792 females...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/29185978/blazing-the-trail-from-volume-to-value
#10
Zachary Hafner
Transforming health care is harder than it looks. That's partly because of a proliferation of pilot programs and point solutions that touch different parts of the elephant but fall short of actually unifying the vision. The time has come to make our way from volume to value.
November 2017: Managed Care
https://www.readbyqxmd.com/read/29173201/duration-of-untreated-psychosis-and-neurocognitive-functioning-in-first-episode-psychosis-a-systematic-review-and-meta-analysis
#11
K Allott, D Fraguas, C F Bartholomeusz, C M Díaz-Caneja, C Wannan, E M Parrish, G P Amminger, C Pantelis, C Arango, P D McGorry, M Rapado-Castro
BACKGROUND: Previous reviews suggest there is minimal evidence for an association between duration of untreated psychosis (DUP) and neurocognition. This is based on tallied findings of studies with small samples and neurocognition viewed as a single construct. We aimed to conduct a systematic review and meta-analysis examining the association between DUP and individual neurocognitive domains and tests in first-episode psychosis (FEP). METHOD: MOOSE and PRISMA guidelines were followed...
November 27, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/29170483/free-running-sn-precipitates-an-efficient-phase-separation-mechanism-for-metastable-ge1-xsnx-epilayers
#12
Heiko Groiss, Martin Glaser, Magdalena Schatzl, Moritz Brehm, Dagmar Gerthsen, Dietmar Roth, Peter Bauer, Friedrich Schäffler
The revival of interest in Ge1-xSnx alloys with x ≥ 10% is mainly owed to the recent demonstration of optical gain in this group-IV heterosystem. Yet, Ge and Sn are immiscible over about 98% of the composition range, which renders epilayers based on this material system inherently metastable. Here, we address the temperature stability of pseudomorphic Ge1-xSnx films grown by molecular beam epitaxy. Both the growth temperature dependence and the influence of post-growth annealing steps were investigated...
November 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29169581/vitamin-d-status-is-associated-with-executive-function-a-decade-later-data-from-the-women-s-healthy-ageing-project
#13
Alicia M Goodwill, Stephen Campbell, Steven Simpson, Maria Bisignano, Cherie Chiang, Lorraine Dennerstein, Cassandra Szoeke
OBJECTIVES: Vitamin D deficiency has been associated with cognitive decline and dementia in older adults. However, there is a paucity of studies assessing whether this association manifests from midlife. Given the long prodromal stage of dementia, we investigated the association between midlife vitamin D and cognition 10 years later. STUDY DESIGN: 252 participants (aged 55-67 years) from the Women's Healthy Ageing Project had baseline (2002) vitamin D and neuropsychological measures assessed...
January 2018: Maturitas
https://www.readbyqxmd.com/read/29168420/vulnerabilities-in-sequencing-and-task-switching-in-healthy-youth-offspring-of-parents-with-mood-disorders
#14
Manpreet K Singh, Sara M Leslie, Kalpa Bhattacharjee, Melina Gross, Elizabeth F Weisman, Laila M Soudi, Owen R Phillips, Alexander Onopa
INTRODUCTION: Visuospatial processing and task switching are impaired in individuals with mood disorders. It is unknown whether early deficits are present before mood symptom on set or are related to risk for a specific type of mood disorder. To investigate, we compared visual attention and task switching during sequencing among never-disordered youth with parental family histories of bipolar (BD) and major depressive disorders (MDD) and healthy controls (HC) with no personal or family history of psychopathology...
November 23, 2017: Journal of Clinical and Experimental Neuropsychology
https://www.readbyqxmd.com/read/29166159/local-regulation-of-trail-networks-of-the-arboreal-turtle-ant-cephalotes-goniodontus
#15
Deborah M Gordon
This study examines how an arboreal ant colony maintains, extends, and repairs its network of foraging trails and nests, built on a network of vegetation. Nodes are junctions where a branch forks off from another or where a branch of one plant touching another provides a new edge on which ants could travel. The ants' choice of edge at a node appears to be reinforced by trail pheromone. Ongoing pruning of the network tends to eliminate cycles and minimize the number of nodes and thus decision points, but not the distance traveled...
December 2017: American Naturalist
https://www.readbyqxmd.com/read/29165535/the-feasibility-of-standardised-geriatric-assessment-tools-and-physical-exercises-in-frail-older-adults
#16
A D Jadczak, N Mahajan, R Visvanathan
Geriatric assessment tools are applicable to the general geriatric population; however, their feasibility in frail older adults is yet to be determined. The study aimed to determine the feasibility of standardised geriatric assessment tools and physical exercises in hospitalised frail older adults. Various assessment tools including the FRAIL Screen, the Charlson Comorbidity Index, the SF-36, the Trail Making Test (TMT), the Rapid Cognitive Screen, the Self Mini Nutritional Assessment (MNA-SF) and the Lawton iADL as well as standard physical exercises were assessed using observational protocols...
2017: Journal of Frailty & Aging
https://www.readbyqxmd.com/read/29163127/post-stroke-fatigue-and-depressive-symptoms-are-differentially-related-to-mobility-and-cognitive-performance
#17
Bradley J MacIntosh, Jodi D Edwards, Mani Kang, Hugo Cogo-Moreira, Joyce L Chen, George Mochizuki, Nathan Herrmann, Walter Swardfager
Background: Fatigue and depressive symptoms are common and often inter-related stroke sequelae. This study investigates how they are related, directly or indirectly, to mobility and cognitive outcomes within 6 months of stroke. Methods: Participants were recruited from 4 stroke centers in Ontario, Canada. Post-stroke fatigue was assessed using the Fatigue Assessment Scale (FAS). Depressive symptoms were screened using the Center for Epidemiological Studies Scale for Depression (CES-D). Factor analyses were used to construct scores from mobility (distance traveled during a 2-min walk test, Chedoke-McMaster Stroke Assessment leg score, and Berg Balance Scale total score) and cognitive (Montreal Cognitive Assessment, Trail-Making Tests A and B, and five-word free recall) tests...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/29160603/relationship-between-self-reported-cognitive-difficulties-objective-neuropsychological-test-performance-and-psychological-distress-in-chronic-pain
#18
K S Baker, S J Gibson, N Georgiou-Karistianis, M J Giummarra
BACKGROUND: Persons with chronic pain often report problems with cognitive abilities, such as memory or attention. There is limited understanding of whether objective performance is consistent with subjective reports, and how psychological factors contribute. We aimed to investigate these relationships in a group of patients expressing cognitive concerns, and evaluate the utility of self-report tools for pain management settings. METHOD: Participants with chronic pain (n = 41) completed standardized neuropsychological tests, and self-report measures of cognitive functioning, pain, mood and sleep, as part of a broader study investigating cognitive performance in pain...
November 21, 2017: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/29159041/white-matter-alterations-and-their-associations-with-motor-function-in-young-adults-born-preterm-with-very-low-birth-weight
#19
Ingrid Marie Husby Hollund, Alexander Olsen, Jon Skranes, Ann-Mari Brubakk, Asta K Håberg, Live Eikenes, Kari Anne I Evensen
Very low birth weight (VLBW: ≤ 1500 g) individuals have an increased risk of white matter alterations and neurodevelopmental problems, including fine and gross motor problems. In this hospital-based follow-up study, the main aim was to examine white matter microstructure and its relationship to fine and gross motor function in 31 VLBW young adults without cerebral palsy compared with 31 term-born controls, at mean age 22.6 ± 0.7 years. The participants were examined with tests of fine and gross motor function (Trail Making Test-5: TMT-5, Grooved Pegboard, Triangle from Movement Assessment Battery for Children-2: MABC-2 and High-level Mobility Assessment Tool: HiMAT) and diffusion tensor imaging (DTI)...
2018: NeuroImage: Clinical
https://www.readbyqxmd.com/read/29156435/more-than-a-to-b-understanding-and-managing-visitor-spatial-behaviour-in-urban-forests-using-public-participation-gis
#20
Silviya Korpilo, Tarmo Virtanen, Tiina Saukkonen, Susanna Lehvävirta
Planning and management needs up-to-date, easily-obtainable and accurate information on the spatial and social aspects of visitor behaviour in order to balance human use and impacts, and protection of natural resources in public parks. We used a web-based public participation GIS (PPGIS) approach to gather citizen data on visitor behaviour in Helsinki's Central Park in order to aid collaborative spatial decision-making. The study combined smartphone GPS tracking, route drawing and a questionnaire to examine differences between user groups in their use of formal trails, off-trail behaviour and the motivations that affect it...
November 17, 2017: Journal of Environmental Management
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