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https://www.readbyqxmd.com/read/28333399/evaluation-of-surface-roughness-characteristics-using-atomic-force-microscopy-and-inspection-of-microhardness-following-resin-infiltration-with-icon-%C3%A2
#1
Elif Beril Gurdogan, Didem Ozdemir-Ozenen, Nuket Sandalli
OBJECTIVE: The aim of this study was to evaluate the surface roughness via atomic force microscopy (AFM) as well as to evaluate the microhardness values of Icon(®) in comparison with sound and demineralized enamel in a large subject group. MATERIALS AND METHODS: Enamel samples were prepared from sound bovine incisors and randomly allocated into either AFM (n = 60) or microhardness (n = 60) groups. The AFM group was divided into control (n = 30) and Icon(®) (n = 30) subgroups...
March 23, 2017: Journal of Esthetic and Restorative Dentistry
https://www.readbyqxmd.com/read/28327302/effect-of-monomer-blend-and-chlorhexidine-adding-on-physical-mechanical-and-biological-properties-of-experimental-infiltrants
#2
Luciana Tiemi Inagaki, Roberta Caroline Bruschi Alonso, Giovana Albamonte Spagnolo Araújo, Eduardo José Carvalho de Souza-Junior, Paula Cristina Anibal, José Francisco Höfling, Fernanda Miori Pascon, Regina Maria Puppin-Rontani
OBJECTIVES: The aim of the study was to evaluate antimicrobial inhibition zone, degree of conversion (DC) and Knoop hardness (KH) of experimental infiltrants. Experimental low viscosity monomer blends were prepared and chlorhexidine diacetate salt (CHX) (0.1% or 0.2%) was added comprising the groups: G1) TEGDMA; G2) TEGDMA/0.1CHX; G3) TEGDMA/0.2CHX; G4) TEGDMA/UDMA; G5) TEGDMA/UDMA/0.1CHX; G6) TEGDMA/UDMA/0.2CHX; G7) TEGDMA/BISEMA; G8) TEGDMA/BISEMA/0.1CHX; G9) TEGDMA/BISEMA/0.2CHX. Icon(®) was used as control group...
December 2016: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/28325014/real-time-monitoring-of-swimming-performance
#3
R Delgado-Gonzalo, A Lemkaddem, Ph Renevey, E Muntane Calvo, M Lemay, K Cox, D Ashby, J Willardson, M Bertschi
This article presents the performance results of a novel algorithm for swimming analysis in real-time within a low-power wrist-worn device. The estimated parameters are: lap count, stroke count, time in lap, total swimming time, pace/speed per lap, total swam distance, and swimming efficiency (SWOLF). In addition, several swimming styles are automatically detected. Results were obtained using a database composed of 13 different swimmers spanning 646 laps and 858.78 min of total swam time. The final precision achieved in lap detection ranges between 99...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28323444/evaluating-driver-drowsiness-countermeasures
#4
John G Gaspar, Timothy L Brown, Chris W Schwarz, John D Lee, Julie Kang, James S Higgins
Objective Driver drowsiness contributes to a substantial number of fatal and non-fatal crashes, with recent estimates attributing up to 21% of fatal crashes to drowsiness. This paper describes recent NHTSA research on in-vehicle drowsiness countermeasures. Recent advances in technology and state detection algorithms have shown success in detecting drowsiness using a variety of data sources, including camera-based eye tracking, steering wheel position, yaw rate, and vehicle lane position. However, detection is just the first step in reducing drowsy driving crashes...
March 21, 2017: Traffic Injury Prevention
https://www.readbyqxmd.com/read/28318286/asking-better-questions-how-presentation-formats-influence-information-search
#5
Charley M Wu, Björn Meder, Flavia Filimon, Jonathan D Nelson
While the influence of presentation formats have been widely studied in Bayesian reasoning tasks, we present the first systematic investigation of how presentation formats influence information search decisions. Four experiments were conducted across different probabilistic environments, where subjects (N = 2,858) chose between 2 possible search queries, each with binary probabilistic outcomes, with the goal of maximizing classification accuracy. We studied 14 different numerical and visual formats for presenting information about the search environment, constructed across 6 design features that have been prominently related to improvements in Bayesian reasoning accuracy (natural frequencies, posteriors, complement, spatial extent, countability, and part-to-whole information)...
March 20, 2017: Journal of Experimental Psychology. Learning, Memory, and Cognition
https://www.readbyqxmd.com/read/28301467/life-is-three-dimensional-and-it-begins-with-molecules
#6
Philip E Bourne
The iconic image of the DNA double helix embodies the central role that three-dimensional structures play in understanding biological processes, which, in turn, impact health and well-being. Here, that role is explored through the eyes of one scientist, who has been lucky enough to have over 150 talented people pass through his laboratory. Each contributed to that understanding. What follows is a small fraction of their story, with an emphasis on basic research outcomes of importance to society at large.
March 2017: PLoS Biology
https://www.readbyqxmd.com/read/28298350/the-acacia-ants-revisited-convergent-evolution-and-biogeographic-context-in-an-iconic-ant-plant-mutualism
#7
Philip S Ward, Michael G Branstetter
Phylogenetic and biogeographic analyses can enhance our understanding of multispecies interactions by placing the origin and evolution of such interactions in a temporal and geographical context. We use a phylogenomic approach-ultraconserved element sequence capture-to investigate the evolutionary history of an iconic multispecies mutualism: Neotropical acacia ants (Pseudomyrmex ferrugineus group) and their associated Vachellia hostplants. In this system, the ants receive shelter and food from the host plant, and they aggressively defend the plant against herbivores and competing plants...
March 15, 2017: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/28295866/mapping-language-to-the-world-the-role-of-iconicity-in-the-sign-language-input
#8
Pamela Perniss, Jenny C Lu, Gary Morgan, Gabriella Vigliocco
Most research on the mechanisms underlying referential mapping has assumed that learning occurs in ostensive contexts, where label and referent co-occur, and that form and meaning are linked by arbitrary convention alone. In the present study, we focus on iconicity in language, that is, resemblance relationships between form and meaning, and on non-ostensive contexts, where label and referent do not co-occur. We approach the question of language learning from the perspective of the language input. Specifically, we look at child-directed language (CDL) in British Sign Language (BSL), a language rich in iconicity due to the affordances of the visual modality...
March 12, 2017: Developmental Science
https://www.readbyqxmd.com/read/28294629/sport-concussion-management-using-facebook-a-feasibility-study-of-an-innovative-adjunct-icon
#9
Osman Hassan Ahmed, Anthony G Schneiders, Paul R McCrory, S John Sullivan
CONTEXT:   Sport concussion is currently the focus of much international attention. Innovative methods to assist athletic trainers in facilitating management after this injury need to be investigated. OBJECTIVE:   To investigate the feasibility of using a Facebook concussion-management program termed iCon (interactive concussion management) to facilitate the safe return to play (RTP) of young persons after sport concussion. DESIGN:   Observational study...
March 15, 2017: Journal of Athletic Training
https://www.readbyqxmd.com/read/28294198/external-and-internal-resin-infiltration-of-natural-proximal-subsurface-caries-lesions-a-valuable-enhancement-of-the-internal-tunnel-restoration
#10
Andrej M Kielbassa, Ina Ulrich, Vanessa D Werth, Christoph Schüller, Wilhelm Frank, Rita Schmidl
OBJECTIVE: The aim of this ex-vivo study was to evaluate both the external and the internal penetration ability of a resin infiltrant into natural proximal and macroscopically intact white spot lesions, and to merge this approach with the internal tunnel preparation concept. METHOD AND MATERIALS: 20 premolars and 20 molars with proximal subsurface lesions (ICDAS, code 2) and respective radiographic lesion depths extending into the middle third of dentin (D2 lesions) were selected and divided into two groups...
March 14, 2017: Quintessence International
https://www.readbyqxmd.com/read/28290967/the-brief-military-career-of-dr-william-h-welch
#11
James K Gilman
INTRODUCTION: The purpose of this article is to examine the Army service of Dr. William H. Welch during World War I. MATERIALS AND METHODS: Archival research utilizing prime source documents in the William H. Welch Collection of the Alan M. Chesney Medical Archives for the Johns Hopkins Medical Institutions. RESULTS: Welch joined the Army at the age of 67 after serving as one of the principal transformational forces for reforming medical education in the United States and founding the first academic institution for educating public health professionals in the United States, the Johns Hopkins School of Public Health and Hygiene...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28290379/deep-tendon-reflex-the-background-story-of-a-simple-technique
#12
Kalyan B Bhattacharyya
Wilhelm Erb and Carl Otto Westphal from Prussia first described the knee jerk in the same issue of the journal Archiv für Psychiatrie und Nervenkrankheiten in January 1875. This article retraces the history of development of 'deep tendon reflex' as an integral clinical sign during every neurological examination. The history of the evolving shapes of the reflex hammer, the iconic trademark and the ultimate signature of a neuroscientist, is also presented.
March 2017: Neurology India
https://www.readbyqxmd.com/read/28290215/genetic-assessment-of-leech-species-from-yak-bos-grunniens-in-the-tract-of-northeast-india
#13
Nilkantha Chatterjee, Bishal Dhar, Debasis Bhattarcharya, Sourabh Deori, Juwar Doley, Joken Bam, Pranab J Das, Asit K Bera, Sitangshu M Deb, Ningthoujam Neelima Devi, Rajesh Paul, Sorokhaibam Malvika, Sankar Kumar Ghosh
Yak is an iconic symbol of Tibet and high altitudes of Northeast India. It is highly cherished for milk, meat, and skin. However, yaks suffer drastic change in milk production, weight loss, etc, when infested by parasites. Among them, infestation by leeches is a serious problem in the Himalayan belt of Northeast India. The parasite feeds on blood externally or from body orifices, like nasopharynx, oral, rectum, etc. But there has been limited data about the leech species infesting the yak in that region because of the difficulties in morphological identification due to plasticity of the body, changes in shape, and surface structure and thus, warrants for the molecular characterization of leech...
March 14, 2017: Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis
https://www.readbyqxmd.com/read/28290121/population-pharmacokinetic-analysis-of-ixazomib-an-oral-proteasome-inhibitor-including-data-from-the-phase-iii-tourmaline-mm1-study-to-inform-labelling
#14
Neeraj Gupta, Paul M Diderichsen, Michael J Hanley, Deborah Berg, Helgi van de Velde, R Donald Harvey, Karthik Venkatakrishnan
Ixazomib is an oral proteasome inhibitor, approved in USA, Canada, Australia and Europe in combination with lenalidomide and dexamethasone, for the treatment of patients with multiple myeloma who have received at least one prior therapy. We report a population pharmacokinetic model-based analysis for ixazomib that was pivotal in describing the clinical pharmacokinetics of ixazomib, to inform product labelling. Plasma concentration-time data were collected from 755 patients who received oral or intravenous ixazomib in once- or twice-weekly schedules in ten trials, including the global phase III TOURMALINE-MM1 study...
March 13, 2017: Clinical Pharmacokinetics
https://www.readbyqxmd.com/read/28286174/imaging-resin-infiltration-into-non-cavitated-carious-lesions-by-optical-coherence-tomography
#15
Hartmut Schneider, Kyung-Jin Park, Claudia Rueger, Dirk Ziebolz, Felix Krause, Rainer Haak
OBJECTIVES: Visualisation of the etching process and resin penetration at white spot carious lesions by spectral domain optical coherence tomography (SD-OCT). MATERIALS AND METHODS: The non-cavitated carious lesions (ICDAS code 2) of four visually preselected extracted human molars and premolars were verified as enamel lesions by micro computed tomography (μCT). One region of interest (ROI) per tooth was marked by two drill-holes in occlusal-cervical direction...
March 9, 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/28277595/a-web-based-application-to-communicate-benefits-and-risks-of-surgical-treatments
#16
Fabienne E Stubenrouch, Marwin Baumann, Dink A Legemate, Dirk T Ubbink
BACKGROUND: In general, communication is an important aspect during surgeon-patient consultations. However, clear communication of the benefits and risks of the possible treatment options can be challenging. Visual presentation of information may increase patient comprehension. We developed and piloted a web-based application that provides graphical representations of the numerical benefits and risks of surgical treatment options. MATERIALS AND METHODS: The app was developed by assessing functional requirements, developing a prototype, pilot-testing and adjusting the prototype, and evaluating the final app...
March 9, 2017: Surgical Technology International
https://www.readbyqxmd.com/read/28275381/dietary-risk-assessment-of-v-atpase-a-dsrnas-on-monarch-butterfly-larvae
#17
Huipeng Pan, Xiaowei Yang, Keith Bidne, Richard L Hellmich, Blair D Siegfried, Xuguo Zhou
By suppressing the expression of genes with essential biological functions, in planta RNAi can negatively affect the development and survival of target pests. As a part of a concerted effort to assess the risks of RNAi transgenic crops on non-target organisms, we developed an in vivo toxicity assay to examine the impacts of ingested dsRNAs incurred to the monarch butterfly, Danaus plexippus (L.), an iconic eco-indicator in North America. To create the worst case scenario, the full-length v-ATPase A cDNAs from the target pest, western corn rootworm, Diabrotica virgifera virgifera, and the non-target D...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28270619/massive-increase-in-visual-range-preceded-the-origin-of-terrestrial-vertebrates
#18
Malcolm A MacIver, Lars Schmitz, Ugurcan Mugan, Todd D Murphey, Curtis D Mobley
The evolution of terrestrial vertebrates, starting around 385 million years ago, is an iconic moment in evolution that brings to mind images of fish transforming into four-legged animals. Here, we show that this radical change in body shape was preceded by an equally dramatic change in sensory abilities akin to transitioning from seeing over short distances in a dense fog to seeing over long distances on a clear day. Measurements of eye sockets and simulations of their evolution show that eyes nearly tripled in size just before vertebrates began living on land...
March 7, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28269468/a-home-automation-based-environmental-sound-alert-for-people-experiencing-hearing-loss
#19
Matthias Mielke, Rainer Bruck
Different assistive technologies are available for deaf people (i.e. deaf, deafened, and hard of hearing). Besides the well-known hearing aid, devices for detection of sound events that occur at home or at work (e.g. doorbell, telephone) are available. Despite the technological progress in the last years and resulting new possibilities, the basic functions and concepts of such devices have not changed. The user still needs special assistive technology that is bound to the home or work environment. In this contribution a new concept for awareness of events in buildings is presented...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28266284/koala-retrovirus-genotyping-analyses-reveal-a-low-prevalence-of-korv-a-in-victorian-koalas-and-an-association-with-clinical-disease
#20
Alistair R Legione, Jade L S Patterson, Pam Whiteley, Simon M Firestone, Megan Curnick, Kate Bodley, Michael Lynch, James R Gilkerson, Fiona M Sansom, Joanne M Devlin
PURPOSE: Koala retrovirus (KoRV) is undergoing endogenization into the genome of koalas in Australia, providing an opportunity to assess the effect of retrovirus infection on the health of a population. The prevalence of KoRV in north-eastern Australia (Queensland and New South Wales) is 100 %, whereas previous preliminary investigations in south-eastern Australia (Victoria) suggested KoRV is present at a lower prevalence, although the values have varied widely. Here, we describe a large study of free-ranging koalas in Victoria to estimate the prevalence of KoRV and assess the clinical significance of KoRV infection in wild koalas...
February 2017: Journal of Medical Microbiology
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