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continously renal replacement therapy

R T Noel Gibney
No abstract text is available yet for this article.
September 2016: Journal of Thoracic Disease
Dorota Wirkus, Aleksandra Jakubus, Radosław Owczuk, Piotr Stepnowski, Monika Paszkiewicz
Continous renal replacement therapy (CRRT) is particularly recommended for septic shock patients in intensive care units. The CRRT technique used most frequently is high volume continuous veno-venous haemofiltration. It provides a high rate of clearance of uremic toxins and inflammatory cytokines. However, it should also be taken into account that substances important for homeostasis may be concurrently unintentionally removed. Accordingly, water-soluble vitamins can be removed during continuous renal replacement therapy, and the estimate of the loss is critical to ensure appropriate supplementation...
September 15, 2016: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
Pavan Kumar Rao Navva, Subramanyam Venkata Sreepada, Karopadi Shivanand Nayak
BACKGROUND: Asia is a huge and populous continent with diverse economies where the status of renal replacement therapy varies among different countries. SUMMARY: The penetration of dialysis is poor among low income countries like India and China. A lack of trained nephrologists and limited numbers of dialysis facilities plague South Asian countries. Most of the hemodialysis centers are in the private sector; the few centers that are government-run or run by charitable organizations cannot meet growing needs...
2015: Blood Purification
Nagendra Madisi, Nira Roopnarinesingh, Jennifer Berkeley
Critical Care Student/Resident CasesSESSION TYPE: Medical Student/Resident Case ReportPRESENTED ON: Tuesday, October 28, 2014 at 04:30 PM - 05:30 PMINTRODUCTION: Approximately one million patients misuse over the counter(OTC) dextromethorphan(DXM)-containing medications each year. Abuse has increased over the years as DXM is easily available and has dose-dependent hallucinogenic properties. Here we present a case of DXM-overdose resulting in serotonin syndrome (SS), a life-threatening condition.CASE PRESENTATION: A 52 year old man with a history of bipolar disorder and prior abuse of DXM, was brought to the ED after being found stiff in a chair and poorly responsive...
October 1, 2014: Chest
Dmytro Khadzhynov, Torsten Slowinski, Ina Lieker, Hans-H Neumayer, Harm Peters
BACKGROUND: Regional citrate anticoagulation (RCA) is increasingly used in patients requiring continuous renal replacement therapy (CRRT). This study evaluated a new RCA protocol based on the Prismaflex® dialysis device and an isotonic citrate solution (prismocitrate) for pre-dilution continous veno-venous hemodiafiltration. METHODS: The Prismaflex®/Prismocitrate-based protocol involved an AN69ST® membrane (Prisma Flex ST100), a blood flow of 120 mL/min, 1.8 L/h Prismocitrate (10 mmol/L citrate/2 mmol/L citric acid) substitution fluid in pre-dilution mode, and 0...
May 2014: Clinical Nephrology
Abdol-Mohammad Kajbafzadeh, Atefeh Zeinoddini, Reza Heidari, Haleh NaserHodjjati, Ali Tourchi
This study is a case report of home-based colonic dialysis (CD) for treating end-stage renal disease in a 20-year-old woman. She had a history of Malone antegrade continence enema (MACE) for treating neuropathic bowel at the age of 11 years. The patient refused any type of renal replacement therapy. However, she agreed to CD through the MACE stoma by changing the colonic irrigation solution to the peritoneal dialysis solution. The patient was discharged with a plasma creatinine (Cr) level of 1.7 mg/dL and blood urea nitrogen (BUN) level of 8 mg/dL...
June 2014: Journal of Pediatric Urology
Yin Zheng, Zhongye Xu, Qiuyu Zhu, Junfeng Liu, Jing Qian, Huaizhou You, Yong Gu, Chuanming Hao, Zheng Jiao, Feng Ding
INTRODUCTION: Regional citrate anticoagulation (RCA) is gaining popularity in continous renal replacement therapy (CRRT) for critically ill patients. The risk of citrate toxicity is a primary concern during the prolonged process. The aim of this study was to assess the pharmacokinetics of citrate in critically ill patients with AKI, and used the kinetic parameters to predict the risk of citrate accumulation in this population group undergoing continuous veno-venous hemofiltration (CVVH) with RCA...
2013: PloS One
W Lisch, S Pitz, G Geerling
Many systemic lysosomal storage disorders show basic corneal opacities already in childhood. The lysosome is a cell organelle, produced by Golgi's apparatus, that is surrounded by a membrane and contains hydrolytic enzymes that break down food molecules, especially proteins and other complex molecules. The ophthalmologist's precise diagnosis of corneal clouding at the slit-lamp may reveal the correct interpretation of the specific lysosomal storage disorder. It is very important to diagnose such diseases as soon as possible because today the development of systemic enzymatic therapies has broadened the therapeutic armamentarium for the current standard of care...
June 2013: Klinische Monatsblätter Für Augenheilkunde
S M Sirrs, H Faghfoury, E M Yoshida, T Geberhiwot
BACKGROUND: Transplantation in patients with inborn errors of metabolism (IEM) may be used as rescue therapy for acute decompensation, organ replacement, or disease-modifying therapy. We sought to quantify the use of transplantation in adults with IEM. METHODS: A 10-question online survey was sent through the email list of adult IEM physicians maintained by the Society for the Study of Inborn Errors of Metabolism and posted on the website of the Society of Inherited Metabolic Diseases...
2013: JIMD Reports
O Okunola, A Akinsola, O Ayodele
AIM: To review available literature on the burden of kidney diseases in Africa from the perspective of acute kidney injury and chronic kidney disease. It also aims to provide information on the status of renal replacement therapy activities, and the emerging roles of the double burden of communicable and non communicable diseases interfacing with the kidney in a continent with distinct environmental, socio-cultural, infrastructural and economical peculiarities. METHODS: A literature search was conducted on the aetiopathogenesis, management options of peculiar diseases causing both acute kidney injury and chronic kidney diseases and renal replacement therapies in Africa...
June 2012: African Journal of Medicine and Medical Sciences
Norbert Lameire, Wim Van Biesen
Remarkable differences in the utilization of peritoneal dialysis (PD) versus other forms of renal replacement therapy (RRT) exist between different continents, countries and even different regions in a given country. Since many years a number of medical and nonmedical barriers against home dialysis, notably PD have been recognized. One of the reasons for the low utilization of home (peritoneal) dialysis is the incomplete presentation of treatment options to the patient with ESRD. This review updates some recent data on the long-term survival of PD patients in comparison with long-term hemodialysis...
2012: Contributions to Nephrology
F A Arogundade, A A Sanusi, M O Hassan, A Akinsola
BACKGROUND: The prevalence of chronic renal failure and End Stage Renal Disease (ESRD) has remained high worldwide and the epidemiology has changed significantly in the last decade in industrialised countries. While there have been significant improvements in these patient's outcomes in developed countries, their state and survival is still appalling in developing countries. OBJECTIVE: To determine the clinical pattern, presentation and management outcomes in our ESRD population over a 19-year period (1989-2007)...
December 2011: African Health Sciences
M Haap, O Tschritter, F Artunc, I Rettig, R Riessen
A hypercalcemic crisis is a life-threatening disease with multiorgan failure due to severe hypercalcemia. If left untreated, a hypercalcemic crisis is associated with a very high mortality and requires immediate diagnostic and therapeutic interventions. Especially a rapid rise to high calcium levels impairs the function of several organ systems and leads to central nervous, renal, cardiovascular and gastrointestinal symptoms. A hypercalcemic crisis is caused in more than 90 % by malignancy or primary hyperparathyreoidism and only in very rare cases by other diseases such as granulomatous diseases or other endocrinological diseases...
May 2012: Deutsche Medizinische Wochenschrift
P K Manchanda, H K Bid
Diagnosis of renal diseases is often delayed owing to the scarcity of trained physicians, lack of facilities, and shortage of funds limits effective management, particularly when it comes to the red zone of renal replacement therapy. The Internetis expected to open up a myriad resource of knowledge and applications for academicians, researchers and clinicians alike in all health care professions across the globe. Also, the Internet has grown rapidly over the years and will inevitably expand even more. Evolving technologies offer modern applications for information management, communications with multimedia and virtual reality...
January 2011: Indian Journal of Nephrology
Wei Wang, Zhong-Kai Liao, Sheng-Shou Hu, Yun-Hu Song, Jie Huang
OBJECTIVE: To summarize and analyze clinical outcomes and experience about using extracorporeal membrane oxygenation (ECMO) in supporting heart transplant patients in the peri-operative period of in Fuwai Hospital retrospectively. METHODS: We performed 131 orthotopic heart transplantations from June 2004 to December 2008. Fourteen cases used veno-artery ECMO (Medtronic Ltd) for mechanical circulatory support in the peri-operative period of heart transplantation...
November 2009: Zhonghua Xin Xue Guan Bing za Zhi
Hasan Abu-Aisha, Sarra Elamin
BACKGROUND: Africa is the world's second-largest and second most populous continent. It is also the poorest and most underdeveloped continent. Struggling to provide the essential health interventions for its occupants, the majority of African countries cannot regard renal replacement therapy a health priority. REVIEW: In 2007, Africa's dialysis population constituted only 4.5% of the world's dialysis population, with a prevalence of 74 per million population (pmp), compared to a global average of 250 pmp...
January 2010: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
G Grasselli, G Foti, N Patroniti, A Giuffrida, B Cortinovis, A Zanella, F Pagni, M Mergoni, A Pesci, A Pesenti
After the first outbreak identified in Mexico in late March 2009, influenza A sustained by a modified H1N1 virus ("swine flu") rapidly spread to all continents. This article describes the first Italian case of life-threatening ARDS associated with H1N1 infection, treated with extracorporeal respiratory assistance (venovenous extracorporeal membrane oxygenation [ECMO]). A 24-year-old, previously healthy man was admitted to the Intensive Care Unit (ICU) of the local hospital for rapidly progressive respiratory failure with refractory impairment of gas exchange unresponsive to rescue therapies (recruitment manoeuvres, pronation and nitric oxide inhalation)...
December 2009: Minerva Anestesiologica
D Broniszczak, H Ismail, P Nachulewicz, M Szymczak, T Drewniak, M Markiewicz-Kijewska, A Kowalski, K Jobs, E Smirska, J Rubik, L Skobejko-Włodarska, P Gastoł, A Mikołajczyk, P Kalicinski
INTRODUCTION: Various congenital and acquired diseases of the lower urinary tract can lead to chronic renal failure requiring renal replacement therapy. AIM: The aim of the study was to assess problems and results of kidney transplantation in children with significant lower urinary tract dysfunction. MATERIALS AND METHODS: Between 1984 and 2007, there were 33 kidney transplantations in children with end-stage renal disease and severe lower tract dysfunction out of 539 kidney transplantations performed in our department...
January 2010: European Journal of Pediatric Surgery
Hong Liang Li, Wei Hong An, Yang Yu Zhao, Xi Zhu
Gestational hyperlipidemic pancreatitis is an uncommon complication of pregnancy that incurs a high risk of morbidity and mortality of both maternal and fetal patients. We described the response of continous renal replacement therapy in a woman with extreme gestational hyperlipidemia and severe pancreatitis. Five consecutive plasma exchanges didn't lead to a remarkable reduction (10.4% and 4.8%, for the first and fourth times, respectively) at triglyceride levels as the literatures have reported, which reveals that plasma exchange and continous veno-venous heamofiltration may be importment, instead of crucial methods in dealing with gestational hyperlipidemic pancreatitis...
October 18, 2009: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
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