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Coagulation

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https://www.readbyqxmd.com/read/28339897/reflex-lupus-anticoagulant-and-coagulation-factor-testing-has-low-utility-in-the-preoperative-surgical-hemostasis-assessment
#1
Stephen P Persaud, Ronald Jackups
No abstract text is available yet for this article.
March 1, 2017: American Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28339875/prediction-of-coagulation-testing-in-underfilled-patient-samples
#2
Adam Cloe, Krzysztof Mikrut, Jonathan Miller
No abstract text is available yet for this article.
March 1, 2017: American Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28335516/marine-diterpenes-molecular-modeling-of-thrombin-inhibitors-with-potential-biotechnological-application-as-an-antithrombotic
#3
Rebeca Cristina Costa Pereira, André Luiz Lourenço, Luciana Terra, Paula Alvarez Abreu, Valéria Laneuville Teixeira, Helena Carla Castro
Thrombosis related diseases are among the main causes of death and incapacity in the world. Despite the existence of antithrombotic agents available for therapy, they still present adverse effects like hemorrhagic risks which justify the search for new options. Recently, pachydictyol A, isopachydictyol A, and dichotomanol, three diterpenes isolated from Brazilian marine brown alga Dictyota menstrualis were identified as potent antithrombotic molecules through inhibition of thrombin, a key enzyme of coagulation cascade and a platelet agonist...
March 20, 2017: Marine Drugs
https://www.readbyqxmd.com/read/28335227/synthesis-of-ball-like-ag-nanorod-aggregates-for-surface-enhanced-raman-scattering-and-catalytic-reduction
#4
Wenjing Zhang, Yin Cai, Rui Qian, Bo Zhao, Peizhi Zhu
In this work, ball-like Ag nanorod aggregates have been synthesized via a simple seed-mediated method. These Ag mesostructures were characterized by scanning electron microscope (SEM), transmission electron microscopy (TEM), ultraviolet-visible spectroscopy (UV-Vis), and X-ray diffraction (XRD). Adding a certain amount of polyvinyl pyrrolidone (PVP) can prolong its coagulation time. These Ag nanorod aggregates exhibit effective SERS effect, evaluated by Rhodamine 6G (R6G) and doxorubicin (DOX) as probe molecules...
May 25, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28334673/presence-of-the-%C3%AE-triketone-herbicide-tefuryltrione-in-drinking-water-sources-and-its-degradation-product-in-drinking-waters
#5
Motoyuki Kamata, Mari Asami, Yoshihiko Matsui
Triketone herbicides are becoming popular because of their herbicidal activity against sulfonylurea-resistant weeds. Among these herbicides, tefuryltrione (TFT) is the first registered herbicide for rice farming, and recently its distribution has grown dramatically. In this study, we developed analytical methods for TFT and its degradation product 2-chloro-4-methylsulfonyl-3-[(tetrahydrofuran-2-yl-methoxy) methyl] benzoic acid (CMTBA). TFT was found frequently in surface waters in rice production areas at concentrations as high as 1...
March 20, 2017: Chemosphere
https://www.readbyqxmd.com/read/28334671/fast-tracking-the-molecular-weight-changes-of-humic-substances-in-coagulation-flocculation-processes-via-fluorescence-eem-parafac
#6
Bilal Aftab, Jin Hur
The removal of a commercial humic acid (HA) and changes in its chemical composition were examined for coagulation/flocculation (C/F) processes based on jar tests using two different coagulants at a wide range of pH. ZrCl4 showed a better performance in eliminating HA than Al2SO4 with the same removal rates at lower dosages. The highest removal rates were found at a neutral pH range (5.0-6.5). The HA was further decomposed into three different humic-like components (C1, C2, and C3) by excitation emission matrix coupled with parallel factor analysis (EEM-PARAFAC)...
March 20, 2017: Chemosphere
https://www.readbyqxmd.com/read/28334666/bio-refractory-dissolved-organic-matter-and-colorants-in-cassava-distillery-wastewater-characterization-coagulation-treatment-and-mechanisms
#7
Ming Zhang, Zhou Wang, Penghui Li, Hua Zhang, Li Xie
An important portion of organic matter and colorants still remain in the biologically treated distillery wastewater, leaving the dark brown and odorous downstream with the heavy loading of chemical oxygen demand and the potential of forming disinfection byproducts. However, those bio-recalcitrant colorants have not been clearly recognized. The current study investigated the features of the bio-refractory organic matter and colorants in a typical distillery effluent, cassava distillery wastewater; special attention was paid to their change and behaviors in the coagulation treatment following the bio-processes...
March 20, 2017: Chemosphere
https://www.readbyqxmd.com/read/28333993/integrated-transcriptomic-and-proteomic-analysis-of-the-molecular-cargo-of-extracellular-vesicles-derived-from-porcine-adipose-tissue-derived-mesenchymal-stem-cells
#8
Alfonso Eirin, Xiang-Yang Zhu, Amrutesh S Puranik, John R Woollard, Hui Tang, Surendra Dasari, Amir Lerman, Andre J van Wijnen, Lilach O Lerman
BACKGROUND: Mesenchymal stromal/stem cell (MSC) transplantation is a promising therapy for tissue regeneration. Extracellular vesicles (EVs) released by MSCs act as their paracrine effectors by delivering proteins and genetic material to recipient cells. To assess how their cargo mediates biological processes that drive their therapeutic effects, we integrated miRNA, mRNA, and protein expression data of EVs from porcine adipose tissue-derived MSCs. METHODS: Simultaneous expression profiles of miRNAs, mRNAs, and proteins were obtained by high-throughput sequencing and LC-MS/MS proteomic analysis in porcine MSCs and their daughter EVs (n = 3 each)...
2017: PloS One
https://www.readbyqxmd.com/read/28333829/acute-traumatic-coagulopathy-the-elephant-in-a-room-of-blind-scientists
#9
Michael A Meledeo, Maryanne C Herzig, James A Bynum, Xiaowu Wu, Anand K Ramasubramanian, Daniel N Darlington, Kristin M Reddoch, Andrew P Cap
Acute traumatic coagulopathy (ATC) is the failure of coagulation homeostasis that can rapidly arise following traumatic injury, hemorrhage, and shock; it is associated with higher injury severity, coagulation abnormalities, and increased blood transfusions. ATC has historically been defined by a prolonged prothrombin time (PT), although newer, more informative measurements of hemostatic function have been employed to improve diagnosis and support clinical decision making. The underlying biochemical mechanisms of and best practice therapeutics for ATC remain under active investigation because of its significant correlation to poor outcomes...
March 22, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28333092/impact-of-coagulant-and-flocculant-addition-to-an-anaerobic-dynamic-membrane-bioreactor-andmbr-treating-waste-activated-sludge
#10
Guido Kooijman, Wilton Lopes, Zhongbo Zhou, Hongxiao Guo, Merle de Kreuk, Henri Spanjers, Jules van Lier
In this work, we investigated the effects of flocculation aid (FA) addition to an anaerobic dynamic membrane bioreactor (AnDMBR) (7 L, 35 °C) treating waste-activated sludge (WAS). The experiment consisted of three distinct periods. In period 1 (day 1-86), the reactor was operated as a conventional anaerobic digester with a solids retention time (SRT) and hydraulic retention time (HRT) of 24 days. In period 2 (day 86-303), the HRT was lowered to 18 days with the application of a dynamic membrane while the SRT was kept the same...
March 23, 2017: Membranes
https://www.readbyqxmd.com/read/28333058/advanced-treatment-of-petrochemical-secondary-effluent-by-fenton-performance-and-organics-removal-characteristics
#11
Min Xu, Changyong Wu, Yuexi Zhou
The Fenton process was used to treat petrochemical secondary effluent. The effects of initial pH, H2O2, and FeSO4·7H2O dosages on chemical oxygen demand (COD) removal, the dissolved organic matter (DOM) removal and the transformation and migration of typical organic matters during the treatment process were investigated. The results showed that the optimum conditions were initial pH of 3.0, H2O2 (30%) dosage of 0.4 mL/L, and FeSO4·7H2O dosage of 1.0 g/L. The highest COD removal efficiency of 61.9% could be achieved for this condition when the average influent COD was 78...
March 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/28332638/water-quality-in-turkey-farms-in-khemisset-morocco-and-potential-risk-factors
#12
A El Allaoui, F Rhazi Filali, A Derouich
The objectives of this study were to assess the microbiological and physical/chemical quality of water in broiler turkey farms in the province of Khemisset (north-western Morocco) and, based on a questionnaire, to ascertain potential risk factors for contamination of drinking water with faecal coliforms. A total of 80 samples were collected and analysed in 20 farms (four from each farm). At the main inlet to the water line at the entrance to each turkey house, 100% of the samples were of unacceptable quality in terms of faecal coliforms, Escherichia coli, faecal streptococci, sulphitereducing anaerobes and enterococci...
December 2016: Revue Scientifique et Technique
https://www.readbyqxmd.com/read/28332273/reducing-the-incidence-of-hepatic-artery-thrombosis-in-pediatric-liver-transplantation-effect-of-microvascular-techniques-and-a-customized-anticoagulation-protocol
#13
William A Ziaziaris, Alexandre Darani, Andrew J A Holland, Angus Alexander, Jonathan Karpelowsky, Pasquale Barbaro, Michael Stormon, Edward O'Loughlin, Albert Shun, Gordon Thomas
We aimed to assess the incidence of HAT over three eras following implementation of microvascular techniques and a customized anticoagulation protocol in a predominantly cadaveric split liver transplant program. We retrospectively reviewed pediatric liver transplants performed between April 1986 and 2016 and analyzed the incidence HAT over three eras. In E1, 1986-2008, each patient received a standard dose of 5 U/kg/h of heparin and coagulation profiles normalized passively. In E2, 2008-2012, microvascular techniques were introduced...
March 22, 2017: Pediatric Transplantation
https://www.readbyqxmd.com/read/28332090/disparities-in-the-clinical-evolution-of-anal-neoplasia-in-an-hiv-infected-cohort
#14
Edward R Cachay, Wollelaw Agmas, Wm Christopher Mathews
BACKGROUND: A recent meta-analysis suggested that anal intraepithelial neoplasia and invasive anal cancer are more prevalent among black men having sex with men (MSM). METHODS: We conducted a retrospective cohort of HIV-infected adult patients under care between 2001 and 2012. Disparities in clinical evolution of anal intraepithelial neoplasia to high-grade squamous intraepithelial lesion (HSIL) and invasive anal cancer were evaluated in a three-state Markov model adjusted for cytology misclassification...
March 23, 2017: Journal of Racial and Ethnic Health Disparities
https://www.readbyqxmd.com/read/28331172/an-anti-coagulation-conundrum-implantation-of-total-artificial-heart-in-a-patient-with-heparin-induced-thrombocytopenia-type-ii
#15
Theodore J Cios, Yuliana Salamanca-Padilla, Dmitri Guvakov
BACKGROUND Heparin-induced thrombocytopenia (HIT) is a rare but life-threatening complication of heparin administration. It can present a major clinical dilemma for physicians caring for patients requiring life-saving urgent or emergent cardiac surgery. Studies have been published examining the use of alternative anticoagulants for patients undergoing cardiopulmonary bypass (CPB), however, evidence does not clearly support any particular approach. Presently, there are no large-scale, prospective randomized studies examining the impact of alternative anticoagulants on clinical outcomes for HIT-positive patients requiring cardiac surgery...
March 23, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28330275/phytochemicals-of-moringa-oleifera-a-review-of-their-nutritional-therapeutic-and-industrial-significance
#16
REVIEW
Ramesh Kumar Saini, Iyyakkannu Sivanesan, Young-Soo Keum
Moringa oleifera Lam., also known as the 'drumstick tree,' is recognized as a vibrant and affordable source of phytochemicals, having potential applications in medicines, functional food preparations, water purification, and biodiesel production. The multiple biological activities including antiproliferation, hepatoprotective, anti-inflammatory, antinociceptive, antiatherosclerotic, oxidative DNA damage protective, antiperoxidative, cardioprotective, as well as folk medicinal uses of M. oleifera (MO) are attributed to the presence of functional bioactive compounds, such as phenolic acids, flavonoids, alkaloids, phytosterols, natural sugars, vitamins, minerals, and organic acids...
December 2016: 3 Biotech
https://www.readbyqxmd.com/read/28330212/paper-wasp-nest-mediated-biosynthesis-of-silver-nanoparticles-for-antimicrobial-catalytic-anticoagulant-and-thrombolytic-applications
#17
Agbaje Lateef, Monsurat A Akande, Sunday A Ojo, Bolaji I Folarin, Evariste B Gueguim-Kana, Lorika S Beukes
Biosynthesis of silver nanoparticles (AgNPs) using nest extract of paper wasp (Polistes sp) was investigated in this work. The AgNPs were characterized by UV-Vis spectroscopy, Fourier transform infrared spectroscopy (FTIR), and transmission electron microscopy (TEM), and evaluated for antibacterial, antifungal, dye degradation, blood anticoagulation, and blood clot dissolution (thrombolytic) activities. The crystalline polydispersed AgNPs with size range of 12.5-95.55 nm absorbed maximally at 428 nm and showed anisotropic structures of sphere, triangle, hexagon, rod, and rhombus...
December 2016: 3 Biotech
https://www.readbyqxmd.com/read/28330182/efficient-single-step-chromatographic-purification-of-recombinant-human-antithrombin-rhat-from-saccharomyces-cerevisiae
#18
Maheswara Reddy Mallu, Sandeep Vemula, Srinivasa Reddy Ronda
Antithrombin (AT) is a glycoprotein that inactivates the several physiological target enzymes of coagulation system. The effect of purification strategies plays a crucial role in getting maximum recovery of yield, purity and biological activity of recombinant human antithrombin (rhAT). In the present work, the task of purifying rhAT from Saccharomyces cerevisiae BY4741 has been carried out using two different approaches such as cross flow filtration (CFF) system and chromatography methods. In the first approach, the protein was concentrated and partially purified through CFF to achieve maximum recovery yield and purity of 87 and 94 %, respectively...
June 2016: 3 Biotech
https://www.readbyqxmd.com/read/28329273/is-surgical-resection-superior-to-bronchoscopic-resection-in-patients-with-symptomatic-endobronchial-hamartoma
#19
Sarah M Abdel Hady, Salma E Elbastawisy, Aly S Hassaballa, Hany H Elsayed
A best evidence topic was written according to a structured protocol. The question addressed was: in surgically fit patients with biopsy proven symptomatic endobronchial hamartoma (EH), is surgical resection superior to bronchoscopic resection in terms of outcome. A total of 756 articles were identified using the reported search, of which 8 represented the best evidence to answer the clinical question. The authors, date, journal, country, study type, population, outcomes and key results are tabulated. Three studies included patients who had either bronchoscopic or surgical treatment of EH in the same study...
February 17, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28328685/whole-blood-transfusion-closest-to-the-point-of-injury-during-french-remote-military-operations
#20
Yann Daniel, Anne Sailliol, Thomas Pouget, Sébastien Peyrefitte, Sylvain Ausset, Christophe Martinaud
To improve the survival of combat casualties, interest in the earliest resort to whole blood (WB) transfusion on the battlefield has been emphasized. Providing volume, coagulation factors, plasma and oxygenation capacity, WB appears actually as an ideal product severe trauma management. WB can be collected in advance, and stored for subsequent utilization, or can be drawn, directly on the battlefield, once a soldier is wounded, from an uninjured companion and immediately transfused.Such concepts require a great control of risks at each step, especially regarding ABO mismatches, and transfusion transmitted diseases...
March 21, 2017: Journal of Trauma and Acute Care Surgery
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