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https://www.readbyqxmd.com/read/29778018/phytochemistry-and-pharmacology-of-anti-depressant-medicinal-plants-a-review
#1
REVIEW
Jeanette Martins, Brijesh S
Stress renders an individual to experience mental pressure and exhaustion which brings about feelings of anxiety, depression, anger and/or other negative emotions. Depression affects a person's state of mind, behaviour, health and is often associated with suicide. The use of anti-depressant drugs as therapeutic agents is associated with symptoms such as, delayed onset of action, side-effects, drug-drug and dietary interactions, sexual dysfunction, cardiac toxicity, etc. Thus, there is need to target these issues and improve current treatment options...
May 16, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29777759/plant-nutraceuticals-as-antimicrobial-agents-in-food-preservation-terpenoids-polyphenols-and-thiols
#2
REVIEW
Ignacio Gutiérrez-Del-Río, Javier Fernández, Felipe Lombó
Synthetic food additives generate a negative perception in consumers. Therefore, food manufacturers search for safer natural alternatives as those involving phytochemicals and plant essential oils. These bioactives have antimicrobial activities widely proved in in vitro tests. Foodborne diseases cause thousands of deaths and millions of infections every year, mainly due to pathogenic bacteria as Salmonella spp., Campylobacter spp., Escherichia coli, Bacillus cereus, Listeria monocytogenes or Staphylococcus aureus...
May 16, 2018: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/29734716/nutraceutical-and-ethnopharmacological-properties-of-vangueria-infausta-subsp-infausta
#3
REVIEW
Alfred Maroyi
Vangueria infausta subsp. infausta (VI) is a nutraceutical with plant parts valued in several cultures for its medicinal properties. Traditionally, VI is used against gastro-intestinal disorders, malaria, pneumonia, cough, menstrual problems, parasitic worms, chest complaints, snake bites, infertility, fever, candidiasis and abdominal pains. This study aims to critically summarize the nutraceutical properties, phytochemistry and pharmacology of VI with a view to provide baseline data required for further investigations on this plant...
May 4, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29705464/management-of-psoriasis-with-nutraceuticals-an-update
#4
Gauravi Raut, Sarika Wairkar
Psoriasis is a chronic skin disorder that speeds up the life cycle of skin cells, typically on the surface of the skin. Additional skin cells form thick scales and red fixes which are awfully itchy and sometimes painful. Although there are many therapeutic systems available to get symptomatic relief, unfortunately replete cure for psoriasis is not yet reported. Moreover, poor treatment outcomes as well as high toxicity profile of drugs makes these therapies more inconvenient to treat psoriasis. In search of alternative and complementary therapy for this disease, the focus has been shifted to nutraceuticals, few of them were reported since ages...
May 2018: Complementary Therapies in Clinical Practice
https://www.readbyqxmd.com/read/29703389/association-of-antioxidant-nutraceuticals-and-acetaminophen-paracetamol-friend-or-foe
#5
REVIEW
Mohamed Abdel-Daim, Abdelrahman Ibrahim Abushouk, Raffaella Reggi, Nagendra Sastry Yarla, Maura Palmery, Ilaria Peluso
Acetaminophen (paracetamol or APAP) is an analgesic and antipyretic drug that can induce oxidative stress-mediated hepatotoxicity at high doses. Several studies reported that antioxidant nutraceuticals, in particular phenolic phytochemicals from dietary food, spices, herbs and algae have hepatoprotective effects. Others, however, suggested that they may negatively impact the metabolism, efficacy and toxicity of APAP. The aim of this review is to discuss the pros and cons of the association of antioxidant nutraceuticals and APAP by reviewing the in vivo evidence, with particular reference to APAP pharmacokinetics and hepatotoxicity...
April 2018: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/29671173/cornus-mas-l-fruit-as-a-potential-source-of-natural-health-promoting-compounds-physico-chemical-characterisation-of-bioactive-components
#6
Marta De Biaggi, Dario Donno, Maria Gabriella Mellano, Isidoro Riondato, Ernest N Rakotoniaina, Gabriele L Beccaro
Interest in new sources of anti-inflammatory and antioxidant compounds has recently become a major research issue, with the cornelian cherry (Cornus mas L.) receiving particular attention for its significant amounts of phenolic compounds and vitamins, which exhibit a wide range of biological and pharmacological properties. This study was aimed at increasing knowledge regarding the cornelian cherry in Italy through the analysis of biologically active substances in the locally available genotype "Chieri"...
April 19, 2018: Plant Foods for Human Nutrition
https://www.readbyqxmd.com/read/29607691/effects-of-ionizing-radiation-on-bio-active-plant-extracts-useful-for-preventing-oxidative-damages
#7
Nadia Mulinacci, Alessio Valletta, Valentina Pasqualetti, Marzia Innocenti, Camilla Giuliani, Maria Bellumori, Giulia De Angelis, Alessia Carnevale, Vittoria Locato, Cristina Di Venanzio, Laura De Gara, Gabriella Pasqua
Humans are exposed to ionizing radiations in medical radiodiagnosis and radiotherapy that cause oxidative damages and degenerative diseases. Airplane pilots, and even more astronauts, are exposed to a variety of potentially harmful factors, including cosmic radiations. Among the phytochemicals, phenols are particularly efficient in countering the oxidative stress. In the present study, different extracts obtained from plant food, plant by-products and dietary supplements, have been compared for their antioxidant properties before and after irradiation of 140 cGy, a dose absorbed during a hypothetical stay of three years in the space...
April 2, 2018: Natural Product Research
https://www.readbyqxmd.com/read/29602084/a-comprehensive-lc-ms-ms-method-validation-for-the-quantitative-investigation-of-37-fingerprint-phytochemicals-in-achillea-species-a-detailed-examination-of-a-coarctata-and-a-monocephala
#8
Mustafa Abdullah Yilmaz, Abdulselam Ertas, Ismail Yener, Mehmet Akdeniz, Oguz Cakir, Muhammed Altun, Ibrahim Demirtas, Mehmet Boga, Hamdi Temel
The current study aims to optimize and validate a comprehensive LC-MS/MS method for the quantification of 37 phytochemicals (15 phenolic acids, 17 flavonoids, 3 non-phenolic organic acids, 1 phenolic aldehyde and 1 benzopyrene) in Achillea species. Though Achillea species were chosen as real life samples, the current method is applicable to a wide range of plant species. The developed method was fully validated in terms of linearity, accuracy (recovery), inter-day and intra-day precision (repeatability), limits of detection and quantification (LOD/LOQ) and relative standard uncertainty (U% at 95% confidence level (k = 2))...
March 10, 2018: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/29597091/a-review-on-phytochemistry-and-therapeutic-uses-of-hibiscus-sabdariffa-l
#9
REVIEW
Ghazala Riaz, Rajni Chopra
Hibiscus sabdariffa L. (roselle) belonging to the Malvaceae family is widely grown in many countries. This plant is often used in the traditional medicine being rich in phytochemicals like polyphenols especially anthocyanins, polysaccharides and organic acids thus having enormous prospective in modern therapeutic uses. The study aimed to review and document all the available evidence and information about the calyces of Hibiscus sabdariffa (roselle) with the special focus on their nutritional composition, bioactive constituents and therapeutic uses...
June 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29594287/citrus-medica-nutritional-phytochemical-composition-and-health-benefits-a-review
#10
REVIEW
Navnidhi Chhikara, Ragni Kour, Sundeep Jaglan, Pawan Gupta, Yogesh Gat, Anil Panghal
Citrus medica (Citron) is an underutilized fruit plant having various bioactive components in all parts of the plant. The major bioactive compounds present are iso-limonene, citral, limonene, phenolics, flavonones, vitamin C, pectin, linalool, decanal, and nonanal, accounting for several health benefits. Pectin and heteropolysachharides also play a major role as dietary fibers. The potential impact of citron and its bioactive components to prevent or reverse destructive deregulated processes responsible for certain diseases has attracted different researchers' attention...
March 29, 2018: Food & Function
https://www.readbyqxmd.com/read/29565317/new-findings-in-prunus-padus-l-fruits-as-a-source-of-natural-compounds-characterization-of-metabolite-profiles-and-preliminary-evaluation-of-antioxidant-activity
#11
Dario Donno, Maria Gabriella Mellano, Marta De Biaggi, Isidoro Riondato, Ernest Naivonirina Rakotoniaina, Gabriele Loris Beccaro
European bird cherry ( Prunus padus L.) has been known since the Middle Ages for its medical/food use and high health-promoting value. This study aimed to assess the potential of these fruits as a source of bioactive compounds through the characterization of its physicochemical traits, nutraceutical properties, phytochemical composition via HPLC fingerprint, and antioxidant capacity. Fully ripened fruits of Prunus padus L. (Colorata cv) were collected in mid-July 2017 in Chieri, north-western Italy. The TPC (194...
March 22, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29534518/nutraceutical-or-pharmacological-potential-of-moringa-oleifera-lam
#12
REVIEW
Xianjuan Kou, Biao Li, Julia B Olayanju, Justin M Drake, Ning Chen
Moringa oleifera Lam. ( M. oleifera ), which belongs to the Moringaceae family, is a perennial deciduous tropical tree, and native to the south of the Himalayan Mountains in northern India. M. oleifera is rich in proteins, vitamin A, minerals, essential amino acids, antioxidants, and flavonoids, as well as isothiocyanates. The extracts from M. oleifera exhibit multiple nutraceutical or pharmacological functions including anti-inflammatory, antioxidant, anti-cancer, hepatoprotective, neuroprotective, hypoglycemic, and blood lipid-reducing functions...
March 12, 2018: Nutrients
https://www.readbyqxmd.com/read/29517797/improving-curcumin-solubility-and-bioavailability-by-encapsulation-in-saponin-coated-curcumin-nanoparticles-prepared-using-a-simple-ph-driven-loading-method
#13
Shengfeng Peng, Ziling Li, Liqiang Zou, Wei Liu, Chengmei Liu, David Julian McClements
Curcumin is a bioactive phytochemical that can be utilized as a nutraceutical or pharmaceutical in functional foods, supplements, and medicines. However, the application of curcumin as a nutraceutical in commercial food and beverage products is currently limited by its low water-solubility, chemical instability, and poor oral bioavailability. In this study, all-natural colloidal delivery systems were developed to overcome these challenges, which consisted of saponin-coated curcumin nanoparticles formed using a pH-driven loading method...
March 1, 2018: Food & Function
https://www.readbyqxmd.com/read/29512337/ultra-fast-liquid-chromatography-coupled-with-electrospray-ionization-time-of-flight-mass-spectrometry-for-the-rapid-phenolic-profiling-of-red-maple-acer-rubrum-leaves
#14
Chunting Li, Navindra P Seeram
The red maple (Acer rubrum) species is economically important to North America because of its sap, which is used to produce maple syrup. In addition, various other red maple plant parts, including leaves, were used as a traditional medicine by the Native Americans. Currently, red maple leaves are being used for nutraceutical and cosmetic applications but there are no published analytical methods for comprehensive phytochemical characterization of this material. Herein, a rapid and sensitive method using liquid chromatography with electrospray ionization time-of-flight tandem mass spectrometry was developed to characterize the phenolics in a methanol extract of red maple leaves and a proprietary phenolic-enriched red maple leaves extract (Maplifa™)...
March 7, 2018: Journal of Separation Science
https://www.readbyqxmd.com/read/29487443/antioxidant-capacity-and-amino-acid-profile-of-millet-bran-wine-and-the-synergistic-interaction-between-major-polyphenols
#15
XiaoXuan Guo, XiaoHong Sha, Ebeydulla Rahman, Yong Wang, BaoPing Ji, Wei Wu, Feng Zhou
Millet bran, the by-product of millet processing industry, contains an abundance of phytochemicals, especially polyphenols. The main objective of this study was brewing antioxidant wine from millet bran, as well as the nutritional evaluation. The total polyphenol content of wine samples was determined by Folin-Ciocalteu colorimetric method, and the antioxidant capacity was evaluated by DPPH radical-scavenging capacity, Trolox equivalent antioxidant capacity (TEAC), and ferric reducing antioxidant power (FRAP)...
March 2018: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/29473425/characterisation-of-nutraceutical-compounds-from-different-parts-of-particular-species-of-citrus-sinensis-ovale-calabrese-by-uhplc-uv-esi-hrms
#16
Rita Celano, Luca Campone, Imma Pagano, Sonia Carabetta, Rosa Di Sanzo, Luca Rastrelli, Anna Lisa Piccinelli, Mariateresa Russo
Consumers are aware of diet causing health problems and therefore there is an increased demand for natural ingredients that are expected to be safe and health-promoting. Many of these compounds belong to the class of flavonoids and can be divided into these five groups: flavanones, flavones, flavonols, flavanols, isoflavones and anthocyanidins. Extracts from citrus fruits are usually used as functional ingredients for several products. The aim of this paper was to develop an UHPLC-UV-ESI-HRMS method to define the metabolite profile of different parts of citrus fruit, of a particular cultivar called 'Ovale Calabrese', and in its main by-products...
February 23, 2018: Natural Product Research
https://www.readbyqxmd.com/read/29466987/antioxidant-capacities-and-total-phenolic-contents-of-20-polyherbal-remedies-used-as-tonics-by-folk-healers-in-phatthalung-and-songkhla-provinces-thailand
#17
Wipawee Chanthasri, Nuntitporn Puangkeaw, Nongluk Kunworarath, Patcharawalai Jaisamut, Surasak Limsuwan, Katesarin Maneenoon, Piyapong Choochana, Sasitorn Chusri
BACKGROUND: Uses of polyherbal formulations have played a major role in traditional medicine. The present study is focused on the formulations used in traditional Thai folkloric medicine as tonics or bracers. Twenty documented polyherbal mixtures, used as nourishing tonics by the folk healers in Phatthalung and Songkhla provinces in southern Thailand, are targeted. Despite traditional health claims, there is no scientific evidence to support the utilization of polyherbal formulations...
February 21, 2018: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/29433194/uplc-qtof-ms-profiling-of-two-psidium-species-and-the-in-vivo-hepatoprotective-activity-of-their-nano-formulated-liposomes
#18
Fatema R Saber, Ghada A Abdelbary, Maha M Salama, Dalia O Saleh, Magda M Fathy, Fathy M Soliman
Liver diseases are major health problem in Egypt influencing lifestyle and economy. The demand for nutraceutical hepatoprotective agents is crucial to ameliorate the side effects of synthetic drugs. The present study aims to evaluate antioxidant and hepatoprotective activities of extracts of Psidium guajava L. and Psidium cattleianum Sabine leaves and their nano-formulated liposomes against paracetamol-induced liver damage in rats. Secondary metabolites profile of P. guajava and P. cattleianum leaves was investigated using UPLC-PDA-ESI-qTOF-MSn...
March 2018: Food Research International
https://www.readbyqxmd.com/read/29432917/polyphenol-extracts-from-dried-sugarcane-inhibit-inflammatory-mediators-in-an-in-vitro-colon-cancer-model
#19
Daniel Bucio-Noble, Liisa Kautto, Christoph Krisp, Malcolm S Ball, Mark P Molloy
Sugarcane is an important crop grown in tropical regions for sugar, and for ethanol production. Sugarcane is also a source of phytochemicals but its nutraceutical potential has been under-explored. We show that ethanol extracts of whole dried sugarcane (WDS) recovers a rich content of polyphenols, flavonoids and antioxidant activity that act on inflammatory mediator proteins. To investigate the mechanisms of this activity, we stimulated SW480 colon cancer cells with lipopolysaccharide, exposed cells to WDS and quantitated changes to the proteome and phosphoproteome using label-free mass spectrometry...
April 15, 2018: Journal of Proteomics
https://www.readbyqxmd.com/read/29409346/the-kinetics-of-thermal-degradation-of-polyphenolic-compounds-from-elderberry-sambucus-nigra-l-extract
#20
Ana-Maria Oancea, Cristina Onofrei, Mihaela Turturică, Gabriela Bahrim, Gabriela Râpeanu, Nicoleta Stănciuc
This main focus of this study was to evaluate the thermal degradation kinetics and the phytochemical characterization of the elderberries extract. Pelargonidin-3-sophoroside and delphinidin-3-glucoside were identified as the major anthocyanin compounds and catechin hydrate as the major flavonoid compound. In order to further understand the action of the heat treatment on the bioactive compounds from elderberry extract, fluorescence studies were also carried out. In general, heating at temperatures ranging from 100 to 150 ℃ for up to 90 min caused a decrease in fluorescence intensity, simultaneously with significant redshifts in λmax suggesting important molecular changes inside the anthocyanins structure, affecting the antioxidant activity...
January 1, 2018: Food Science and Technology International, Ciencia y Tecnología de Los Alimentos Internacional
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