Peter Kubatka, Alena Mazurakova, Lenka Koklesova, Tomas Kuruc, Marek Samec, Karol Kajo, Klaudia Kotorova, Marian Adamkov, Karel Smejkal, Emil Svajdlenka, Dana Dvorska, Dusan Brany, Eva Baranovicova, Vladimira Sadlonova, Jan Mojzis, Martin Kello
Introduction: Based on extensive data from oncology research, the use of phytochemicals or plant-based nutraceuticals is considered an innovative tool for cancer management. This research aimed to analyze the oncostatic properties of Salvia officinalis L. [Lamiaceae; Salviae officinalis herba] using animal and in vitro models of breast carcinoma (BC). Methods: The effects of dietary administered S. officinalis in two concentrations (0.1%/SAL 0.1/and 1%/SAL 1/) were assessed in both syngeneic 4T1 mouse and chemically induced rat models of BC...
2024: Frontiers in Pharmacology