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https://www.readbyqxmd.com/read/28802244/detoxification-of-diphenyl-ether-herbicide-lactofen-by-bacillus-sp-za-and-enantioselective-characteristics-of-an-esterase-gene-lace
#1
Jing Zhang, Luyao Lu, Feng Chen, Lingling Chen, Jingang Yin, Xing Huang
A bacterial strain Za capable of degrading diphenyl ether herbicide lactofen was isolated and identified as Bacillus sp. This strain could degrade 94.8% of 50mgL(-1) lactofen after 4days of inoculation in flasks. It was revealed that lactofen was initially hydrolyzed to desethyl lactofen, which was further transformed to acifluorfen, followed by the reduction of the nitro group to yield aminoacifluorfen. The phytotoxicity of the transformed product aminoacifluorfen to maize was decreased significantly compared with the lactofen...
August 3, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28790370/duplication-events-downstream-of-irx1-cause-north-carolina-macular-dystrophy-at-the-mcdr3-locus
#2
Valentina Cipriani, Raquel S Silva, Gavin Arno, Nikolas Pontikos, Ambreen Kalhoro, Sandra Valeina, Inna Inashkina, Mareta Audere, Katrina Rutka, Bernard Puech, Michel Michaelides, Veronica van Heyningen, Baiba Lace, Andrew R Webster, Anthony T Moore
Autosomal dominant North Carolina macular dystrophy (NCMD) is believed to represent a failure of macular development. The disorder has been linked to two loci, MCDR1 (chromosome 6q16) and MCDR3 (chromosome 5p15-p13). Recently, non-coding variants upstream of PRDM13 (MCDR1) and a duplication including IRX1 (MCDR3) have been identified. However, the underlying disease-causing mechanism remains uncertain. Through a combination of sequencing studies on eighteen NCMD families, we report two novel overlapping duplications at the MCDR3 locus, in a gene desert downstream of IRX1 and upstream of ADAMTS16...
August 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28772129/the-effects-of-ankle-braces-and-taping-on-lower-extremity-running-kinematics-and-energy-expenditure-in-healthy-non-injured-adults
#3
Kaori Tamura, Kara N Radzak, Rachele E Vogelpohl, Bethany A Wisthoff, Yukiya Oba, Ronald K Hetzler, Christopher D Stickley
Ankle braces and taping are commonly used to prevent ankle sprains and allow return to play following injury, however, it is unclear how passive restriction of joint motion may effect running gait kinematics and energy expenditure during exercise. The purpose of this study was to determine the effect of different types of ankle supports on lower extremity kinematics and energy expenditure during continuous running. Thirteen healthy physically active adults ran at self-selected speed on the treadmill for 30min in four different ankle support conditions: semi-rigid hinged brace, lace-up brace, tape and control...
July 18, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28771704/parallel-environmental-factors-drive-variation-in-insect-density-and-plant-resistance-in-the-native-and-invaded-ranges
#4
Yuzu Sakata, Timothy P Craig, Joanne K Itami, Michimasa Yamasaki, Takayuki Ohgushi
Geographic variation in the traits of a species is shaped by variation in abiotic conditions, biotic interactions, and evolutionary history of its interactions with other species. We studied the geographic variation in the density of the lace bug, Corythucha marmorata, and the resistance of tall goldenrod Solidago altissima to the lace bug herbivory in their native range in the USA and invaded range in Japan. We conducted field surveys and reciprocal transplant experiments to examine what abiotic and biotic factors influence variation in lace bug density, and what ecological and evolutionary factors predict the resistance of the host plant between and within the native and invaded ranges...
August 3, 2017: Ecology
https://www.readbyqxmd.com/read/28770430/effect-of-selenium-application-on-arsenic-uptake-in-rice-oryza-sativa-l
#5
Sumandeep Kaur, Dhanwinder Singh, Kuldip Singh
Alluvial aquifers of the agrarian state of Punjab of southwestern arid zone used for irrigation of rice crops are rich in arsenic concentration. In the present study, rice (Oryza sativa L.) crops were raised in pots in a greenhouse with a purpose to study whether selenium (Se) application was effective in ameliorating As uptake. The rice crop was irrigated with arsenic laced water (0, 2.5, 5.0, 10.0 μM As L(-1)) throughout the growing period, without and with selenium (0.05 and 0.10 mg kg(-1)) added through mustard biomass, grown ex situ in seleniferous soil...
September 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28750417/prediction-of-potentially-avoidable-readmission-risk-in-a-division-of-general-internal-medicine
#6
Marc Uhlmann, Estelle Lécureux, Anne-Claude Griesser, Hong Dung Duong, Olivier Lamy
INTRODUCTION: The 30-day post-discharge readmission rate is a quality indicator that may reflect suboptimal care. The computerised algorithm SQLape® can retrospectively identify a potentially avoidable readmission (PARA) with high sensitivity and specificity. We retrospectively analysed the hospital stays of patients readmitted to the Department of Internal Medicine of the CHUV (Centre Hospitalier Universitaire Vaudois) in order to quantify the proportion of PARAs and derive a risk prediction model...
July 27, 2017: Swiss Medical Weekly
https://www.readbyqxmd.com/read/28747875/effects-of-high-definition-anodal-transcranial-direct-current-stimulation-applied-simultaneously-to-both-primary-motor-cortices-on-bimanual-sensorimotor-performance
#7
Nils H Pixa, Fabian Steinberg, Michael Doppelmayr
Many daily activities, such as tying one's shoe laces, opening a jar of jam or performing a free throw in basketball, require the skillful coordinated use of both hands. Even though the non-invasive method of transcranial direct current stimulation (tDCS) has been repeatedly shown to improve unimanual motor performance, little is known about its effects on bimanual motor performance. More knowledge about how tDCS may improve bimanual behavior would be relevant to motor recovery, e.g., in persons with bilateral impairment of hand function...
2017: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/28743602/menthol-disrupts-nicotine-s-psychostimulant-properties-in-an-age-and-sex-dependent-manner-in-c57bl-6j-mice
#8
Benjamin W Fait, David C Thompson, Tenna N Mose, Peter Jatlow, Sven E Jordt, Marina R Picciotto, Yann S Mineur
Menthol is a commonly used flavorant in tobacco and e-cigarettes, and could contribute to nicotine sensitivity. To understand how menthol could contribute to nicotine intake and addiction, it is important to determine whether specific mechanisms related to sex and age could underlie behavioral changes induced by menthol-laced nicotinic products. Using a validated paradigm of nicotine-dependent locomotor stimulation, adolescent and adult C57BL/6J mice of both sexes were exposed to nicotine, or nicotine laced with menthol, as their sole source of fluid, and psychostimulant effects were evaluated by recording home cage locomotor activity for ten days...
July 22, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28742370/a-community-grows-around-the-geysering-world-of-enceladus
#9
Carolyn C Porco
The discovery by NASA's Cassini mission at Saturn in 2005 of a large plume of material erupting from the south polar terrain of Enceladus, sourced within a subsurface ocean of salty liquid water laced with organic compounds, has brought together scientists from a diverse range of disciplines over the last decade to evaluate this small moon's potential for extraterrestrial life. The collection of papers published today in Astrobiology, as the mission draws to a close, is the outcome of our most recent meeting at UC Berkeley in June 2016...
July 25, 2017: Astrobiology
https://www.readbyqxmd.com/read/28728975/continuous-nitrogen-removal-by-a-single-stage-reactor-packed-with-ring-laced-string-medium
#10
Masahiro Tatara, Shu Ishikawa, Yoshiyuki Ueno
The efficiency of nitrogen removal by a partial-nitritation/anammox (PNA) reaction was investigated using a packed-bed reactor in which ring-laced strings were used as the supporting medium. A stable population of PNA microorganisms was established from typical activated sludge, after less than two months of acclimation in the packed-bed reactor, by applying a high nitrogen-loading rate (NLR: 0.53 kg/m(3)/d) and short hydraulic retention time (HRT: 1.8 h). The stability of reactor performance was confirmed in industrial wastewater (IW), demonstrating a nitrogen removal efficiency (NRE) of greater than 77% during 260 days of continuous operation, between 0...
July 17, 2017: Journal of Bioscience and Bioengineering
https://www.readbyqxmd.com/read/28710226/evaluating-the-predictive-strength-of-the-lace-index-in-identifying-patients-at-high-risk-of-hospital-readmission-following-an-inpatient-episode-a-retrospective-cohort-study
#11
Sarah Damery, Gill Combes
OBJECTIVE: To assess how well the LACE index and its constituent elements predict 30-day hospital readmission, and to determine whether other combinations of clinical or sociodemographic variables may enhance prognostic capability. DESIGN: Retrospective cohort study with split sample design for model validation. SETTING: One large hospital Trust in the West Midlands. PARTICIPANTS: All alive-discharge adult inpatient episodes between 1 January 2013 and 31 December 2014...
July 13, 2017: BMJ Open
https://www.readbyqxmd.com/read/28709684/hairpin-structures-with-conserved-sequence-motifs-determine-the-3-ends-of-non-polyadenylated-invertebrate-iridovirus-transcripts
#12
İkbal Agah İnce, Gorben P Piljman, Just M Vlak, Monique M van Oers
Previously, we observed that the transcripts of Invertebrate iridescent virus 6 (IIV6) are not polyadenylated, in line with the absence of canonical poly(A) motifs (AATAAA) downstream of the open reading frames (ORFs) in the genome. Here, we determined the 3' ends of the transcripts of fifty-four IIV6 virion protein genes in infected Drosophila Schneider 2 (S2) cells. By using ligation-based amplification of cDNA ends (LACE) it was shown that the IIV6 mRNAs often ended with a CAUUA motif. In silico analysis showed that the 3'-untranslated regions of IIV6 genes have the ability to form hairpin structures (22-56 nt in length) and that for about half of all IIV6 genes these 3' sequences contained complementary TAATG and CATTA motifs...
July 11, 2017: Virology
https://www.readbyqxmd.com/read/28708848/predicting-all-cause-risk-of-30-day-hospital-readmission-using-artificial-neural-networks
#13
Mehdi Jamei, Aleksandr Nisnevich, Everett Wetchler, Sylvia Sudat, Eric Liu
Avoidable hospital readmissions not only contribute to the high costs of healthcare in the US, but also have an impact on the quality of care for patients. Large scale adoption of Electronic Health Records (EHR) has created the opportunity to proactively identify patients with high risk of hospital readmission, and apply effective interventions to mitigate that risk. To that end, in the past, numerous machine-learning models have been employed to predict the risk of 30-day hospital readmission. However, the need for an accurate and real-time predictive model, suitable for hospital setting applications still exists...
2017: PloS One
https://www.readbyqxmd.com/read/28699940/association-of-stress-biomarkers-with-30-day-unplanned-readmission-and-death
#14
Carole Aubert, Antoine Folly, Marco Mancinetti, Daniel Hayoz, Jacques Donze
BACKGROUND: The theory that posthospitalization stress might increase the risk of postdischarge complications has never been investigated. OBJECTIVE: To assess whether serum levels of stress biomarkers at discharge are associated with readmission and death after an acute-care hospitalization. DESIGN: We prospectively included 346 patients aged ≥50 years admitted to the department of general internal medicine at a large community hospital between April 8, 2013 and September 23, 2013...
July 2017: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
https://www.readbyqxmd.com/read/28699480/adulteration-practices-of-psychoactive-illicit-drugs-an-updated-review
#15
Renata Solimini, Maria Concetta Rotolo, Manuela Pellegrini, Adele Minutillo, Roberta Pacifici, Francesco Paolo Busardò, Simona Zaami
BACKGROUND: It is well known that powdery drugs such as cocaine and heroin are frequently adulterated or diluted predominantly to obtain more doses and to increase the drug dealer's profits, but also to enhance, to modify or to oppose drug effects. METHODS: The aim of this report is to provide an overview of the recent scientific literature on medicines as well as on new psychoactive substances, used as cutting agents (i.e. pharmacologically active adulterants) and on the related adverse health effects on consumers, possibly due to the synergistic effect of the adulterants laced with substances of abuse, which represent a matter of great concern because of the frequent fatalities...
July 10, 2017: Current Pharmaceutical Biotechnology
https://www.readbyqxmd.com/read/28692616/development-of-a-falls-registry-a-pilot-study
#16
Gina M Berg, Tara Carlson, Joanne Fairchild, Courtney Edwards, Ryan Sorell
Each year approximately 1 in 4 healthy older adults aged 65+ years and 1 in 2 aged 80+ years living in the community will fall. Fall-related injuries are the leading cause of death and disability and cost the United States approximately $31 billion annually. Currently, no repository of scene data exists that informs prevention programs regarding circumstances that contribute to older adult falls. This was a multicenter (4 sites: Kansas, Maryland, Oregon, and Texas) pilot study consisting of interviews of older (55+ years) patients who had been admitted to a trauma center with fall-related injuries...
July 2017: Journal of Trauma Nursing: the Official Journal of the Society of Trauma Nurses
https://www.readbyqxmd.com/read/28682665/can-life-begin-on-enceladus-a-perspective-from-hydrothermal-chemistry
#17
David Deamer, Bruce Damer
Enceladus is a target of future missions designed to search for existing life or its precursors. Recent flybys of Enceladus by the Cassini probe have confirmed the existence of a long-lived global ocean laced with organic compounds and biologically available nitrogen. This immediately suggests the possibility that life could have begun and may still exist on Enceladus. Here we will compare the properties of two proposed sites for the origin of life on Earth-hydrothermal vents on the ocean floor and hydrothermal volcanic fields at the surface-and ask whether similar conditions could have fostered the origin of life on Enceladus...
July 6, 2017: Astrobiology
https://www.readbyqxmd.com/read/28674666/who-are-the-important-predators-of-sea-turtle-nests-at-wreck-rock-beach
#18
Juan Lei, David T Booth
Excessive sea turtle nest predation is a problem for conservation management of sea turtle populations. This study assessed predation on nests of the endangered loggerhead sea turtle (Caretta caretta) at Wreck Rock beach adjacent to Deepwater National Park in Southeast Queensland, Australia after a control program for feral foxes was instigated. The presence of predators on the nesting dune was evaluated by tracking plots (2 × 1 m) every 100 m along the dune front. There were 21 (2014-2015) and 41 (2015-2016) plots established along the dune, and these were monitored for predator tracks daily over three consecutive months in both nesting seasons...
2017: PeerJ
https://www.readbyqxmd.com/read/28661204/user-survey-of-3-ankle-braces-in-soccer-volleyball-and-running-which-brace-fits-best
#19
Kasper Janssen, Anjulie Van Den Berg, Willem Van Mechelen, Evert Verhagen
CONTEXT:   Recurrence rates for ankle sprains are high. Therefore, preventive measures such as ankle bracing during sports are recommended. OBJECTIVE:   To systematically evaluate the perceived ease of use, quality, comfort, stability, and hindrance of and the overall satisfaction with 3 contemporary brace types in 3 types of sports. DESIGN:   Randomized comparative user survey. SETTING:   Recreational sports: soccer, volleyball, and running...
August 2017: Journal of Athletic Training
https://www.readbyqxmd.com/read/28655333/deworming-of-stray-dogs-and-wild-canines-with-praziquantel-laced-baits-delivered-by-an-unmanned-aerial-vehicle-in-areas-highly-endemic-for-echinococcosis-in-china
#20
Qing Yu, Ning Xiao, Shi-Jie Yang, Shuai Han
BACKGROUND: Canines, the definitive hosts for the parasites causing alveolar (AE) and cystic echinococcosis (CE), are the main source of this infections playing the key role in the transmission. The ten-year mortality rate of AE is extremely high (94%) if the patients are not given sustained treatment. The aim of this field study is to explore the possibility of delivery of praziquantel-laced baits using unmanned aerial vehicles (UAVs) aimed at deworming wild canines in the endemic areas...
June 27, 2017: Infectious Diseases of Poverty
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