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https://www.readbyqxmd.com/read/28420258/lace-up-for-healthy-feet-the-impact-of-shoe-closure-on-plantar-stress-response
#1
Hadi Rahemi, David G Armstrong, Ana Enriquez, Joshua Owl, Talal K Talal, Bijan Najafi
OBJECTIVE: This study examined the impact of shoe closure on plantar thermal stress response (TSR), which is known to be a surrogate of shear stress and skin perfusion. It is aimed to explore potential impact of shoe closure on increasing risk factors associated with plantar ulcers in people with diabetic peripheral neuropathy (DPN). METHODS: Fifteen eligible subjects were enrolled. The left foot was used as a reference and fitted to a self-adjusted and habitual lace-tightening method by each subject...
April 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/28409951/electron-number-based-phase-diagram-of-pr_-1-x-lace_-x-cuo_-4-%C3%AE-and-possible-absence-of-disparity-between-electron-and-hole-doped-cuprate-phase-diagrams
#2
Dongjoon Song, Garam Han, Wonshik Kyung, Jeongjin Seo, Soohyun Cho, Beom Seo Kim, Masashi Arita, Kenya Shimada, Hirofumi Namatame, Masaki Taniguchi, Y Yoshida, H Eisaki, Seung Ryong Park, C Kim
We performed annealing and angle resolved photoemission spectroscopy studies on electron-doped cuprate Pr_{1-x}LaCe_{x}CuO_{4-δ} (PLCCO). It is found that the optimal annealing condition is dependent on the Ce content x. The electron number (n) is estimated from the experimentally obtained Fermi surface volume for x=0.10, 0.15 and 0.18 samples. It clearly shows a significant and annealing dependent deviation from the nominal x. In addition, we observe that the pseudo-gap at hot spots is also closely correlated with n; the pseudogap gradually closes as n increases...
March 31, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28390405/fam-face-sg-a-score-for-risk-stratification-of-frequent-hospital-admitters
#3
Lian Leng Low, Nan Liu, Kheng Hock Lee, Marcus Eng Hock Ong, Sijia Wang, Xuan Jing, Julian Thumboo
BACKGROUND: An accurate risk stratification tool is critical in identifying patients who are at high risk of frequent hospital readmissions. While 30-day hospital readmissions have been widely studied, there is increasing interest in identifying potential high-cost users or frequent hospital admitters. In this study, we aimed to derive and validate a risk stratification tool to predict frequent hospital admitters. METHODS: We conducted a retrospective cohort study using the readily available clinical and administrative data from the electronic health records of a tertiary hospital in Singapore...
April 8, 2017: BMC Medical Informatics and Decision Making
https://www.readbyqxmd.com/read/28389868/remodelling-of-lace-plant-leaves-antioxidants-and-ros-are-key-regulators-of-programmed-cell-death
#4
Adrian N Dauphinee, Jacob I Fletcher, Georgia L Denbigh, Christian R Lacroix, Arunika H L A N Gunawardena
Antioxidants and reactive oxygen species are integral for programmed cell death signaling during perforation formation in the lace plant ( Aponogeton madagascariensis ). The lace plant is an excellent model system for studying developmentally regulated programmed cell death (PCD). During early lace plant leaf development, PCD systematically deletes cells resulting in a perforated leaf morphology that is unique in planta. A distinct feature in young lace plant leaves is an abundance of anthocyanins, which have antioxidant properties...
April 7, 2017: Planta
https://www.readbyqxmd.com/read/28367375/the-hospital-score-and-lace-index-as-predictors-of-30-day-readmission-in-a-retrospective-study-at-a-university-affiliated-community-hospital
#5
Robert Robinson, Tamer Hudali
INTRODUCTION: Hospital readmissions are common, expensive, and a key target of the Medicare Value Based Purchasing (VBP) program. Validated risk assessment tools such as the HOSPITAL score and LACE index have been developed to identify patients at high risk of hospital readmission so they can be targeted for interventions aimed at reducing the rate of readmission. This study aims to evaluate the utility of HOSPITAL score and LACE index for predicting hospital readmission within 30 days in a moderate-sized university affiliated hospital in the midwestern United States...
2017: PeerJ
https://www.readbyqxmd.com/read/28350928/effect-of-total-laparoscopic-hysterectomy-vs-total-abdominal-hysterectomy-on-disease-free-survival-among-women-with-stage-i-endometrial-cancer-a-randomized-clinical-trial
#6
RANDOMIZED CONTROLLED TRIAL
Monika Janda, Val Gebski, Lucy C Davies, Peta Forder, Alison Brand, Russell Hogg, Thomas W Jobling, Russell Land, Tom Manolitsas, Marcelo Nascimento, Deborah Neesham, James L Nicklin, Martin K Oehler, Geoff Otton, Lewis Perrin, Stuart Salfinger, Ian Hammond, Yee Leung, Peter Sykes, Hextan Ngan, Andrea Garrett, Michael Laney, Tong Yow Ng, Karfai Tam, Karen Chan, C David Wrede, Selvan Pather, Bryony Simcock, Rhonda Farrell, Gregory Robertson, Graeme Walker, Nigel R Armfield, Nick Graves, Anthony J McCartney, Andreas Obermair
Importance: Standard treatment for endometrial cancer involves removal of the uterus, tubes, ovaries, and lymph nodes. Few randomized trials have compared disease-free survival outcomes for surgical approaches. Objective: To investigate whether total laparoscopic hysterectomy (TLH) is equivalent to total abdominal hysterectomy (TAH) in women with treatment-naive endometrial cancer. Design, Setting, and Participants: The Laparoscopic Approach to Cancer of the Endometrium (LACE) trial was a multinational, randomized equivalence trial conducted between October 7, 2005, and June 30, 2010, in which 27 surgeons from 20 tertiary gynecological cancer centers in Australia, New Zealand, and Hong Kong randomized 760 women with stage I endometrioid endometrial cancer to either TLH or TAH...
March 28, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28317167/semiparametric-methods-for-estimation-of-a-nonlinear-exposure-outcome-relationship-using-instrumental-variables-with-application-to-mendelian-randomization
#7
James R Staley, Stephen Burgess
Mendelian randomization, the use of genetic variants as instrumental variables (IV), can test for and estimate the causal effect of an exposure on an outcome. Most IV methods assume that the function relating the exposure to the expected value of the outcome (the exposure-outcome relationship) is linear. However, in practice, this assumption may not hold. Indeed, often the primary question of interest is to assess the shape of this relationship. We present two novel IV methods for investigating the shape of the exposure-outcome relationship: a fractional polynomial method and a piecewise linear method...
May 2017: Genetic Epidemiology
https://www.readbyqxmd.com/read/28303812/global-eradication-of-measles-are-we-poised
#8
REVIEW
Raghavendra D Kulkarni, G S Ajantha, Aithal R Kiran, K R Pravinchandra
Measles, a highly infectious viral disease is the next target for eradication following poliovirus. Decades of experience with highly effective vaccination has invigorated us to take on this virus. The task is not only Titanic but is laced with intricate issues. Recently, an outbreak of fever with rash occurred on a tertiary care teaching hospital campus and was confirmed serologically as measles outbreak by IgMELISA. Therefore, we searched the literature related to outbreaks, transmission of the measles virus, age groups involved, vaccination strategies, vaccination failure and epidemiological features of the disease and reviewed the possible reasons for such outbreaks and problems in the global eradication of the virus...
January 2017: Indian Journal of Medical Microbiology
https://www.readbyqxmd.com/read/28274908/assessing-the-performance-of-a-modified-lace-index-lace-rt-to-predict-unplanned-readmission-after-discharge-in-a-community-teaching-hospital
#9
Christo El Morr, Liane Ginsburg, Seungree Nam, Susan Woollard
BACKGROUND: The LACE index was designed to predict early death or unplanned readmission after discharge from hospital to the community. However, implementing the LACE tool in real time in a teaching hospital required practical unavoidable modifications. OBJECTIVE: The purpose of this study was to validate the implementation of a modified LACE index (LACE-rt) and test its ability to predict readmission risk using data in a hospital setting. METHODS: Data from the Canadian Institute for Health Information's Discharge Abstract Database (DAD), the National Ambulatory Care Reporting System (NACRS), and the hospital electronic medical record for one large community hospital in Toronto, Canada, were used in this study...
March 8, 2017: Interactive Journal of Medical Research
https://www.readbyqxmd.com/read/28268113/fentanyl-laced-heroin-and-its-contribution-to-a-spike-in-heroin-overdose-in-miami-dade-county
#10
Alexander Diaz Bode, Mallika Singh, James Andrews, Girish D Kapur, Amado Alejandro Baez
No abstract text is available yet for this article.
February 28, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28257671/nonsurgical-management-of-midsubstance-achilles-tendinopathy
#11
REVIEW
Shane McClinton, Lace Luedke, Derek Clewley
Midsubstance Achilles tendinopathy is one of the most common lower leg conditions. Most patients can recover with nonsurgical treatment that focuses on tendon loading exercises and, when necessary, symptom modulating treatments such as topical, oral, or injected medication, ice, shoe inserts, manual therapy, stretching, taping, or low-level laser. If unresponsive to initial management, a small percentage of patients may consider shockwave or sclerosing treatment and possibly surgery.
April 2017: Clinics in Podiatric Medicine and Surgery
https://www.readbyqxmd.com/read/28235886/the-pearl-score-predicts-90-day-readmission-or-death-after-hospitalisation-for-acute-exacerbation-of-copd
#12
C Echevarria, J Steer, K Heslop-Marshall, S C Stenton, P M Hickey, R Hughes, M Wijesinghe, R N Harrison, N Steen, A J Simpson, G J Gibson, S C Bourke
BACKGROUND: One in three patients hospitalised due to acute exacerbation of COPD (AECOPD) is readmitted within 90 days. No tool has been developed specifically in this population to predict readmission or death. Clinicians are unable to identify patients at particular risk, yet resources to prevent readmission are allocated based on clinical judgement. METHODS: In participating hospitals, consecutive admissions of patients with AECOPD were identified by screening wards and reviewing coding records...
February 24, 2017: Thorax
https://www.readbyqxmd.com/read/28220975/thermodynamic-stability-of-heterodimetallic-lnln-complexes-synthesis-and-dft-studies
#13
Joan Gónzalez-Fabra, Nuno A G Bandeira, Verónica Velasco, Leoní A Barrios, David Aguilà, Simon J Teat, Olivier Roubeau, Carles Bo, Guillem Aromí
The solid-state and solution configurations of the heterodimetallic complexes (Hpy)[LaEr(HL)3 (NO3 )(py)(H2 O)] (1), (Hpy)[CeEr(HL)3 (NO3 )(py)(H2 O)] (2), (Hpy)[CeGd(HL)3 (NO3 )(py)(H2 O)] (3), (Hpy)[PrSm(HL)3 (NO3 )(py)(H2 O)] (4), and (Hpy)2 [LaYb(HL)3 (NO3 )(H2 O)](NO3 ) (5), in which H3 L is 6-(3-oxo-3-(2-hydroxyphenyl)propionyl)pyridine-2-carboxylic acid and py is pyridine, were analyzed experimentally and by using DFT calculations. Complexes 3, 4, and 5 are described here for the first time, and were analyzed by using single-crystal X-ray diffraction and mass spectrometry...
February 21, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28166873/effect-of-work-boot-type-on-work-footwear-habits-lower-limb-pain-and-perceptions-of-work-boot-fit-and-comfort-in-underground-coal-miners
#14
Jessica A Dobson, Diane L Riddiford-Harland, Alison F Bell, Julie R Steele
Lower limb injuries are highly prevalent in underground coal mining. Wearing gumboots with inadequate ankle support was thought to contribute to these injuries. Despite the uptake of leather lace-up boots, which provide more ankle support, no recent research could be found investigating the effect of this alternative work boot in underground coal mining. Consequently, this study aimed to determine whether boot type (gumboot, leather lace-up boot) influenced work footwear habits, foot problems, lower limb pain, lower back pain, or perceptions of work boot fit and comfort in underground coal miners...
April 2017: Applied Ergonomics
https://www.readbyqxmd.com/read/28158759/a-cluster-of-fentanyl-laced-heroin-deaths-in-2015-in-melbourne-australia
#15
Luke N Rodda, Jennifer L Pilgrim, Matthew Di Rago, Kerryn Crump, Dimitri Gerostamoulos, Olaf H Drummer
The prevalence of opioid use in therapeutic and recreational settings has steadily increased throughout the western world. The addition of fentanyl into heroin products can produce potentially dangerous consequences, even to opioid tolerant individuals who may be unaware of such additions. Following an observed spike of heroin-fentanyl related deaths in Melbourne, Australia, a study was undertaken to determine the prevalence of these cases. All reportable deaths occurring in Victoria during 2015 and submitted to the toxicology laboratory were analysed using LC-MS-MS to confirm the combination of the heroin marker 6-acetylmorphine and/or morphine, and fentanyl...
May 1, 2017: Journal of Analytical Toxicology
https://www.readbyqxmd.com/read/28156510/predicting-hospital-readmissions-in-the-oncology-population
#16
Kristine A Donovan, Mary Turney, C Edward Emnett, Amber Lamoreaux, Diane G Portman
177 Background: The 30-day readmission rate is established as an important indicator of quality of care. The LACE index is commonly used in the general medical setting to predict readmission but its ability to predict readmission with sensitivity and specificity in the oncology population has not yet been examined. At our cancer center, palliative care (PC) consultation is associated with an increased risk for readmission but it is not an element in the LACE index. METHODS: We sought to characterize the operating characteristics of the LACE Index using receiver operating characteristics analyses to predict unplanned readmissions to our cancer center over a 6-week period beginning March 2016...
October 9, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28113666/uncertainty-visualization-by-representative-sampling-from-prediction-ensembles
#17
Le Liu, Alexander Boone, Ian Ruginski, Lace Padilla, Mary Hegarty, Sarah H Creem-Regehr, William B Thompson, Cem Yuksel, Donald H House
Data ensembles are often used to infer statistics to be used for a summary display of an uncertain prediction. In a spatial context, these summary displays have the drawback that when uncertainty is encoded via a spatial spread, display glyph area increases in size with prediction uncertainty. This increase can be easily confounded with an increase in the size, strength or other attribute of the phenomenon being presented. We argue that by directly displaying a carefully chosen subset of a prediction ensemble, so that uncertainty is conveyed implicitly, such misinterpretations can be avoided...
September 8, 2016: IEEE Transactions on Visualization and Computer Graphics
https://www.readbyqxmd.com/read/28068563/a-review-fentanyl-and-non-pharmaceutical-fentanyls
#18
REVIEW
Joji Suzuki, Saria El-Haddad
BACKGROUND: Fentanyl and non-pharmaceutical fentanyls (NPFs) have been responsible for numerous outbreaks of overdoses all over the United States since the 1970s. However, there has been a growing concern in recent years that NPFs are contributing to an alarming rise in the number of opioid-related overdoses. METHODS: The authors conducted a narrative review of the published and grey literature on fentanyl and NPFs in PubMed, Google Scholar, and Google using the following search terms: "fentanyl", "non-pharmaceutical fentanyl", "fentanyl analogs", "fentanyl laced heroin" and "fentanyl overdose"...
February 1, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28045940/applying-the-integrated-practice-unit-concept-to-a-modified-virtual-ward-model-of-care-for-patients-at-highest-risk-of-readmission-a-randomized-controlled-trial
#19
Lian Leng Low, Shu Yun Tan, Matthew Joo Ming Ng, Wei Yi Tay, Lee Beng Ng, Kanchana Balasubramaniam, Rachel Marie Towle, Kheng Hock Lee
BACKGROUND: Emerging evidence from the virtual ward care model showed that multidisciplinary case management are inadequate to reduce readmissions or death for high risk patients. There is consensus that interventions should encompass both pre-hospital discharge and post-discharge transitional care to be effective. Integrated practice units (IPU) had been proposed as an approach of restructuring the organization and work processes of multidisciplinary teams to achieve value in healthcare...
2017: PloS One
https://www.readbyqxmd.com/read/28045179/heck-functionalization-of-an-asymmetric-aza-bodipy-core-synthesis-of-far-red-infrared-probes-for-bioimaging-applications
#20
Stefano Parisotto, Beatrice Lace, Emma Artuso, Chiara Lombardi, Annamaria Deagostino, Roberto Scudu, Claudio Garino, Claudio Medana, Cristina Prandi
As part of our ongoing work on the synthesis of a new class of plant hormones named Strigolactones (SLs) and their analogues, we became interested in tracing bioactive molecules with red emitting BODIPY fluorophores in order to unravel signaling and distribution of SLs in plants. In this paper we report on an unprecedented Heck functionalization of azadipyrromethenes (aza-DIPY) which allows for the introduction of suitable functional groups to convert aza-BODIPY in bioconjugate complexes useful for untangling biological processes...
January 3, 2017: Organic & Biomolecular Chemistry
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