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Synthia Lay, Long L Nguyen, Arul Sangani
In this case report, we present an 82-year-old female who was diagnosed with catatonia after she exhibited immobility, mutism, withdrawal, and stereotypy during a hospitalization for altered mental status. Fentanyl was found in her urine toxicology, and it was later discovered that she had been taking non-prescription pills from Mexico that were likely the source of the fentanyl. Her catatonia quickly remitted with benzodiazepine treatment. This case underscores previously unknown risks of substance use, which has grown especially important to psychiatric care considering how rampant the opioid epidemic has become...
March 2024: Curēus
#2
JOURNAL ARTICLE
Ralph T Schär, Mattia Branca, Andreas Raabe, C Marvin Jesse
Retrospective cohort study. To assess the utility of the LACE index for predicting death and readmission in patients with spinal infections (SI). SIs are severe conditions, and their incidence has increased in recent years. The LACE (Length of stay, Acuity of admission, Comorbidities, Emergency department visits) index quantifies the risk of mortality or unplanned readmission. It has not yet been validated for SIs. LACE indices were calculated for all adult patients who underwent surgery for spinal infection between 2012 and 2021...
April 17, 2024: Neurosurgical Review
#3
JOURNAL ARTICLE
Leo C E Huberts, Sihan Li, Victoria Blake, Louisa Jorm, Jennifer Yu, Sze-Yuan Ooi, Blanca Gallego
BACKGROUND: Cardiovascular patients experience high rates of adverse outcomes following discharge from hospital, which may be preventable through early identification and targeted action. This study aimed to investigate the effectiveness and explainability of machine learning algorithms in predicting unplanned readmission and death in cardiovascular patients at 30 days and 180 days from discharge. METHODS: Gradient boosting machines were trained and evaluated using data from hospital electronic medical records linked to hospital administrative and mortality data for 39,255 patients admitted to four hospitals in New South Wales, Australia between 2017 and 2021...
March 20, 2024: Computers in Biology and Medicine
#4
Angela C Chi, Enrique Schubert, Keyur Naik, Arshad Kaleem, Jonathan Lavezo, Eleanor Chen, Yajuan J Liu, Yu Wu, John D Reith, Hans C Brockhoff
The calcified chondroid mesenchymal neoplasm (CCMN) represents a recently recognized tumor type with only 50 well-documented cases in the English-language literature. Herein we report an additional case of CCMN presenting as a large mass in the temporomandibular joint region of a 41-year-old female. A review of previously reported cases and the current case of CCMN shows the following features: 1) average age 52 years (range 14-87 years) and an approximately even sex distribution; 2) most frequently involved sites: distal extremities (including foot, hand, wrist, forearm) (n=41) and temporomandibular joint/temporal/parotid region (n=9); 3) multilobular soft tissue tumor with chondroid to cartilaginous matrix, often grungy or lace-like calcifications, and variable cytologic atypia; 4) frequently detected FN1 rearrangement (n=15), including FN1 fusion with FGFR2 (n=7) or other receptor tyrosine kinases; 5) 2 reported local recurrences (after incomplete excision); 6) no reports of malignant biologic behavior...
January 11, 2024: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
#5
JOURNAL ARTICLE
Alex Reichenbach, Harry Dempsey, Zane B Andrews
Hunger increases the motivation for calorie consumption, often at the expense of low-taste appeal. However, the neural mechanisms integrating calorie-sensing with increased motivation for calorie consumption remain unknown. Agouti-related peptide (AgRP) neurons in the arcuate nucleus of the hypothalamus sense hunger, and the ingestion of caloric solutions promotes dopamine release in the absence of sweet taste perception. Therefore, we hypothesised that metabolic-sensing of hunger by AgRP neurons would be essential to promote dopamine release in the nucleus accumbens in response to caloric, but not non-caloric solutions...
April 10, 2024: Journal of Neuroendocrinology
#6
JOURNAL ARTICLE
Jinwen Zhao, Xingrong Tan, Ying He, Ruo Yuan, Shentang Wang, Shihong Chen
Currently reported aggregation-induced electroluminescence (AIECL) is usually based on the electrostatic integration of luminous monomers, and its application is still limited by the low ECL efficiency and poor structural stability of electrostatic integration-based AIECL emitters. Herein, host-guest recognition-mediated supramolecular AIECL was creatively developed to overcome the defects of electrostatic-integration-based AIECL. Cucurbit[8]uril (CB[8]) as the host recognized tris (2-phenylpyridine) iridium(III) [Ir(ppy)3 ] as the guest to form a novel supramolecular complex Ir-CB[8]...
April 10, 2024: Analytical Chemistry
#7
A Reghan Foley, Véronique Bolduc, Fady Guirguis, Sandra Donkervoort, Ying Hu, Rotem Orbach, Riley M McCarty, Apurva Sarathy, Gina Norato, Beryl B Cummings, Monkol Lek, Anna Sarkozy, Russell J Butterfield, Janbernd Kirschner, Andrés Nascimento, Daniel Natera-de Benito, Susana Quijano-Roy, Tanya Stojkovic, Luciano Merlini, Giacomo Comi, Monique Ryan, Denise McDonald, Pinki Munot, Grace Yoon, Edward Leung, Erika Finanger, Meganne E Leach, James Collins, Cuixia Tian, Payam Mohassel, Sarah B Neuhaus, Dimah Saade, Benjamin T Cocanougher, Mary-Lynn Chu, Mena Scavina, Carla Grosmann, Randal Richardson, Brian D Kossak, Sidney M Gospe, Vikram Bhise, Gita Taurina, Baiba Lace, Monica Troncoso, Mordechai Shohat, Adel Shalata, Sophelia H S Chan, Manu Jokela, Johanna Palmio, Göknur Haliloğlu, Cristina Jou, Corine Gartioux, Herimela Solomon-Degefa, Carolin D Freiburg, Alvise Schiavinato, Haiyan Zhou, Sara Aguti, Yoram Nevo, Ichizo Nishino, Cecilia Jimenez-Mallebrera, Shireen R Lamandé, Valérie Allamand, Francesca Gualandi, Alessandra Ferlini, Daniel G MacArthur, Steve D Wilton, Raimund Wagener, Enrico Bertini, Francesco Muntoni, Carsten G Bönnemann
Collagen VI-related dystrophies (COL6-RDs) manifest with a spectrum of clinical phenotypes, ranging from Ullrich congenital muscular dystrophy (UCMD), presenting with prominent congenital symptoms and characterised by progressive muscle weakness, joint contractures and respiratory insufficiency, to Bethlem muscular dystrophy, with milder symptoms typically recognised later and at times resembling a limb girdle muscular dystrophy, and intermediate phenotypes falling between UCMD and Bethlem muscular dystrophy...
March 29, 2024: medRxiv
#8
JOURNAL ARTICLE
Elena Ciccone, Antonio Bosco, Paola Pepe, Martina Nocerino, Nicola Lattero, Gerald Umhang, Laatamna AbdElkarim, Samia Lahmar, Yousra Said, Giorgio Saralli, Giuseppe Piegari, Maria Chiara Alterisio, Rania Baka, Smaragda Sotiraki, Franck Boué, Laura Rinaldi
Cystic echinococcosis (CE), caused by the larval stage of the cestode Echinococcus granulosus, is one of the most widespread zoonoses in Mediterranean countries. Baiting not-owned dogs with praziquantel (PZQ), due to their key role in the maintaining the transmission of CE, currently appears to be the most effective way to limit the transmission of CE, as well as an important aspect to introduce for the control of this parasitic disease. Therefore, this study aims to test 3 types of PZQ-based baits by evaluating different parameters (integrity over time, attractiveness and palatability for dogs, and mechanical resistance after release to different altitudes) and the bait acceptance in field by target animals, i...
March 12, 2024: Parasitology
#9
JOURNAL ARTICLE
Rachel K Surowiec, Olivia N Reul, Nusaiba N Chowdhury, Ratan K Rai, Dyann Segvich, Andrew A Tomaschke, John Damrath, Andrea M Jacobson, Matthew R Allen, Joseph M Wallace
INTRODUCTION: Patients with chronic kidney disease (CKD) are at an alarming risk of fracture compared to age and sex-matched non-CKD individuals. Clinical and preclinical data highlight two key factors in CKD-induced skeletal fragility: cortical porosity and reduced matrix-level properties including bone hydration. Thus, strategies are needed to address these concerns to improve mechanical properties and ultimately lower fracture risk in CKD. We sought to evaluate the singular and combined effects of mechanical and pharmacological interventions on modulating porosity, bone hydration, and mechanical properties in CKD...
April 3, 2024: Bone
#10
JOURNAL ARTICLE
Gautam Singh Parmar, Ashish Agrawal, Ashok Meena, Priyanka Mutha, Bharat Gurnani
Management of large acute corneal hydrops (ACH) has always been a challenge. Various medical and surgical management options have been used, such as topical steroids, cycloplegics, antiglaucoma medications, antibiotics, Descemet's membrane reposition, and pre-Descematic sutures, for the management of acute hydrops, but have shown limited benefit. We hereby describe a novel technique of appositional continuous overlay sutures along with air tamponade for surgical management of corneal edema following large ACH...
April 1, 2024: Indian Journal of Ophthalmology
#11
JOURNAL ARTICLE
Jacob S Budin, Timothy L Waters, Lacee K Collins, Matthew W Cole, Julianna E Winter, Bela P Delvadia, Michael C Iloanya, William F Sherman
BACKGROUND: Urinary incontinence has been linked to worse postoperative pain, decreased physical function, and reduced quality of life in patients following total joint arthroplasty. The purpose of this study was to analyze whether incontinence is associated with increased postoperative medical and joint complications following primary total hip arthroplasty (THA) and total knee arthroplasty (TKA). METHODS: A retrospective cohort study was conducted using a national insurance database...
June 2024: Arthroplasty Today
#12
(no author information available yet)
Retraction: Ashraf S, Shah K, Ali M, Jain S. Fentanyl-laced marijuana use in adolescents: a rising concern nationwide. Prim Care Companion CNS Disord. 2024;26(1):23lr03598. https://doi.org/10.4088/PCC.23lr03598. The above letter to the editor, published online on February 6, 2024, in The Primary Care Companion for CNS Disorders has been retracted by agreement between the authors and the journal Editor-in-Chief, Larry Culpepper. The retraction has been agreed upon per the authors' request to retract the letter, as the authors want to correct the references to support the key statements...
March 3, 2024: Primary Care Companion to CNS Disorders
#13
JOURNAL ARTICLE
Md Shahjahan Hossain, Hossein Ebrahimi, Ranajay Ghosh
We synthesize geometrically tailorable anisotropic plates by combining button shaped fish-scale like features on soft substrates, then lacing them with high-stiffness strings. This creates a new type of biomimetic architectured structure with multiple broken symmetries. First, the tendons and substrate together break the symmetry of the bending response between the concave and convex curvature. Next, the weave pattern of the tendons further breaks symmetry along the two directors of plates. The anisotropy is clearly evident in 3-point bending experiments...
March 15, 2024: Journal of the Mechanical Behavior of Biomedical Materials
#14
JOURNAL ARTICLE
Henrique Galante, Tomer J Czaczkes
Argentine ants Linepithema humile are one of the most damaging invasive alien species worldwide. Enhancing or disrupting cognitive abilities, such as learning, has the potential to improve management efforts, for example by increasing preference for a bait, or improving ants' ability to learn its characteristics or location. Nectar-feeding insects are often the victims of psychoactive manipulation, with plants lacing their nectar with secondary metabolites such as alkaloids and non-protein amino acids which often alter learning, foraging, or recruitment...
February 2024: Current Zoology
#15
JOURNAL ARTICLE
Lacee A Satcher, Christy L Erving, Richard N Pitt
Using data from the National Survey of American Life (NSAL) (2001-2003), we examine regional differences in past-year anxiety disorder and past-year major depressive episodes among a geographically diverse sample of Black Americans (N = 3,672). We find that Black Americans residing in the South experience a mental health advantage over Black Americans living in other parts of the country, experiencing lower rates of both anxiety disorder and past-year major depression. We also examine the extent to which stress exposure, religious involvement, and neighborhood contexts help explain any regional differences...
March 11, 2024: Journal of Racial and Ethnic Health Disparities
#16
JOURNAL ARTICLE
Chi-Minh Truong, Yung-Cheng Jair, Hong-Po Chen, Wei-Chih Chen, Yi-Hsin Liu, Pin-Chuan Chen, Pai-Shan Chen
BACKGROUND: High-resolution matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS) and nuclear magnetic resonance (NMR) spectroscopy are powerful tools to identify unknown psychoactive substances. However, in complex matrices, trace levels of unknown substances usually require additional fractionation and concentration. Specialized liquid chromatography systems are necessary for both techniques. The small flow rate of nano LC, typically paired with MALDI-TOF MS, often results in prolonged fractionation times...
April 15, 2024: Analytica Chimica Acta
#17
JOURNAL ARTICLE
Wesley Davis, Joan Stanley, Michelle Buck, Elizabeth Walters, Sean DeGarmo
Understanding the historical context and contemporary trends in advanced practice registered nurse (APRN) education and regulation is pivotal for effective professional advocacy. Until the release of the APRN Consensus Model in 2008, a uniform model for APRN regulation was lacking. Adopting the model's recommendations has implications for APRNs beyond licensure and regulation, including full practice authority, license portability, and patient access to APRN-led care. A comprehensive understanding of APRN education and regulation empowers nurses, APRNs, and stakeholders to drive the profession forward through informed advocacy...
March 15, 2024: AACN Advanced Critical Care
#18
JOURNAL ARTICLE
Jiashen Cai, Dorothy Huang, Hanis Binte Abdul Kadir, Zhihua Huang, Li Choo Ng, Andrew Ang, Ngiap Chuan Tan, Yong Mong Bee, Wei Yi Tay, Chieh Suai Tan, Cynthia C Lim
AIMS: Hospital readmissions due to recurrent fluid overload in diabetes and diabetic kidney disease can be avoided with evidence-based interventions. We aimed to identify at-risk patients who can benefit by developing risk prediction models for readmissions for fluid overload in people living with diabetes. METHODS: Single-center retrospective cohort study of 1531 adults with diabetes and hospitalized for fluid overload, including congestive heart failure, pulmonary edema and generalized edema, between 2015 and 2017...
March 6, 2024: Nephron
#19
JOURNAL ARTICLE
Mohammad Hosseini, Alex O Holcombe, Marton Kovacs, Hub Zwart, Daniel S Katz, Kristi Holmes
Group authorship (also known as corporate authorship, team authorship, consortium authorship) refers to attribution practices that use the name of a collective (be it team, group, project, corporation, or consortium) in the authorship byline. Data shows that group authorships are on the rise but thus far, in scholarly discussions about authorship, they have not gained much specific attention. Group authorship can minimize tensions within the group about authorship order and the criteria used for inclusion/exclusion of individual authors...
March 6, 2024: Accountability in Research
#20
JOURNAL ARTICLE
Helia Hosseinpour, Laura E Matzen, Kristin M Divis, Spencer C Castro, Lace Padilla
Small multiples are a popular visualization method, displaying different views of a dataset using multiple frames, often with the same scale and axes. However, there is a need to address their potential constraints, especially in the context of human cognitive capacity limits. These limits dictate the maximum information our mind can process at once. We explore the issue of capacity limitation by testing competing theories that describe how the number of frames shown in a display, the scale of the frames, and time constraints impact user performance with small multiples of line charts in an energy grid scenario...
March 4, 2024: IEEE Transactions on Visualization and Computer Graphics
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