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https://www.readbyqxmd.com/read/29046004/-coronary-computed-tomography-angiography-in-patients-with-stable-coronary-artery-disease
#1
Helen Ullrich, Tommaso Gori
The guidelines on the management of stable coronary artery disease (SCAD) recommend the use of coronary computed tomography angiography (CTA) in the process of diagnosing coronary artery disease in patients with low intermediate pre-test probability for SCAD. Particularly in cases where stress electrocardiogram or stress imaging provides unclear results, a computed tomographic examination can be considered as a reliable alternative to invasive coronary angiography. Due to its high negative predictive value, coronary CTA can provide accurate information on the presence of coronary artery stenosis and thus coronary artery disease can be reliably excluded without the risks associated with invasive procedures...
October 2017: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/29045602/does-routinely-collected-patient-reported-outcome-data-represent-the-actual-case-mix-of-elective-coronary-revascularization-patients
#2
Salla Oinasmaa, Jari Heiskanen, Juha Hartikainen, Mikko Hippeläinen, Heikki Miettinen, Janne Martikainen, Risto P Roine, Anna-Maija Tolppanen
Aims: Patient-reported outcomes (PROs) are valuable for effectiveness evaluation, but it is unknown whether the patient views obtained represent the actual case mix. We studied the representativeness of the responses obtained to a routinely administered health-related quality of life (HRQoL) questionnaire in a cardiology unit. Methods and results: Elective coronary artery bypass grafting (CABG; N = 404) and percutaneous coronary intervention (PCI; N = 738) patients operated during 6/2012-8/2014 in the Heart Center, Kuopio University Hospital...
October 13, 2017: European Heart Journal. Quality of Care & Clinical Outcomes
https://www.readbyqxmd.com/read/29045041/orbital-and-rotational-atherectomy-during-percutaneous-coronary-intervention-for-coronary-artery-calcification
#3
Michael S Lee, Jonathan S Gordin, Gregg W Stone, Samin K Sharma, Shigeru Saito, Ehtisham Mahmud, Jeff Chambers, Philippe Généreux, Richard Shlofmitz
Severe coronary artery calcification (CAC) increases the complexity of percutaneous coronary intervention (PCI) by inhibiting optimal stent expansion, leading to an increased risk of death, myocardial infarction, repeat revascularization, and stent thrombosis. Coronary atherectomy modifies and debulks calcified plaque to facilitate PCI. Although there is no clear consensus, and further studies are needed, the decision to perform atherectomy should be based upon the presence of fluoroscopic CAC or with the use of intravascular imaging...
October 17, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29044976/transcoronary-pacing-to-assess-myocardial-viability-prior-to-percutaneous-coronary-intervention-pilot-study-to-assess-feasibility
#4
James O'Neill, Andrew J Hogarth, Ian Pearson, Hannah Law, Robert Bowes, Ananth Kidambi, Stephen Wheatcroft, U Mohanaraj Sivananthan, Muzahir H Tayebjee
BACKGROUND: The assessment of myocardial viability is crucial before percutaneous coronary intervention (PCI) is carried out to ensure that the patient will gain benefit. Trans-coronary pacing (TCP) has previously been used to pace myocardium but may also provide information on myocardial viability. METHODS: Patients with a single, significant coronary stenosis requiring PCI were recruited. They underwent a cardiac MRI to assess myocardial viability. Prior to PCI, a coronary guidewire was used to measure pacing threshold, impedance, and R-wave amplitude in different myocardial segments to determine any association between the electrical parameters and myocardial viability...
October 16, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29044931/a-novel-technique-for-simultaneous-hemostasis-of-ipsilateral-radial-and-ulnar-artery-access-sites
#5
Jonathan S Roberts, Jianli Niu
With the increased use of transradial artery access (TRA) for diagnostic and coronary interventional procedures, crossover to the ipsilateral ulnar artery after TRA failure is being reported more frequently. A major challenge with ipsilateral transradial and ulnar artery access is achieving efficient patent hemostasis of both the radial and ulnar arteries at the completion of the procedure. In this report, we describe two cases of failed TRA with subsequent ipsilateral ulnar artery access. A novel and practical technique of simultaneous patent hemostasis of both the ipsilateral radial and ulnar artery access sites is described, using a QuikClot(®) Radial(®) hemostasis pad and a TR Band(®) ...
October 17, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29044926/optical-coherence-tomography-guided-carotid-artery-stent-procedure-technique-and-potential-applications
#6
Suhail Dohad, Alexander Zhu, Sandeep Krishnan, Frances Wang, Serena Wang, Justin Cox, Timothy D Henry
OBJECTIVES: To (1) present a guide on how to perform optical coherence tomography (OCT) in carotid artery stenting (CAS), to (2) highlight several instructive cases illustrating OCT-guidance as an interventional strategy, and to (3) present the largest case-series of OCT-guided CAS performed in North America, demonstrating its feasibility as an imaging modality in this setting. BACKGROUND: OCT is an intravascular imaging method that captures images with an axial resolution 10 times higher than intravascular ultrasound...
October 16, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29044395/modelling-total-coronary-heart-disease-burden-and-long-term-benefit-of-cholesterol-lowering-in-middle-aged-men-with-and-without-a-history-of-cardiovascular-disease
#7
Chris J Packard, Robin Young, Kevin Ross, Ian Ford, Baishali M Ambegaonkar, Philippe Brudi, Colin McCowan
Aims: Cumulative coronary heart disease (CHD) events over 20 years were examined in men screened for, and in those randomized to, the West of Scotland Coronary Prevention Study. Methods and results: Record linkage provided CHD-related events and days in hospital for the 80 230 screenees, including the randomized cohort of 6595 men. Risk factors were determined at baseline, and disease burden assessed for groups defined by cholesterol. Effects of cholesterol lowering were modelled from differences between groups, and from the treatment arms of the trial...
October 1, 2017: European Heart Journal. Quality of Care & Clinical Outcomes
https://www.readbyqxmd.com/read/29044393/duration-of-dual-antiplatelet-therapy-and-associated-outcomes-following-percutaneous-coronary-intervention-for-acute-myocardial-infarction-contemporary-practice-insights-from-the-canadian-observational-antiplatelet-study
#8
Juan J Russo, Shaun G Goodman, Akshay Bagai, Jean-Pierre Déry, Mary K Tan, Harold N Fisher, Xiang Zhang, Yajun Emily Zhu, Robert C Welsh, Anthony Della Siega, Andre Kokis, Brian Y L Wong, Mark Henderson, Sohrab Lutchmedial, Shahar Lavi, Shamir R Mehta, Andrew T Yan
Aims: There is a paucity of real-world, contemporary data of practice patterns and clinical outcomes following dual-antiplatelet therapy (DAPT) in acute myocardial infarction (AMI) patients treated with percutaneous coronary intervention (PCI). Methods and results: The Canadian Observational Antiplatelet Study was a prospective, multicentre, cohort study examining adenosine diphosphate receptor antagonist use following PCI for AMI. We compared practice patterns, patient characteristics, and clinical outcomes in relation to DAPT duration (<6 weeks, 6 weeks to <6 months, 6 to <12, and ≥12 months)...
October 1, 2017: European Heart Journal. Quality of Care & Clinical Outcomes
https://www.readbyqxmd.com/read/29044298/the-performance-of-crusade-and-acuity-bleeding-risk-scores-in-ticagrelor-treated-acs-patients-who-underwent-pci
#9
Shaozhi Xi, Shanshan Zhou, Xuyun Wang, Jia Liu, Liuan Qin, Jun Liu, Tong Yin, Yundai Chen
The performance of the CRUSADE (Can Rapid risk stratification of Unstable angina patients Suppress ADverse outcomes with Early implementation of the ACC/AHA guidelines) and ACUITY (Acute Catheterization and Urgent Intervention Triage strategy) risk scores for the prediction of major bleeding in ticagrelor-treated acute coronary syndrome (ACS) patients who underwent percutaneous coronary intervention (PCI) is unknown. The aim of the present study is to validate the performance of both scores in a contemporary Chinese cohort of ACS patients hospitalized for PCI and administrated with ticagrelor...
October 10, 2017: Thrombosis and Haemostasis
https://www.readbyqxmd.com/read/29044291/preprocedural-leucocyte-count-predicts-risk-in-patients-with-coronary-chronic-total-occlusion
#10
Catherine Gebhard, Aurel Toma, Zhao Min, Barbara E Stähli, Kambis Mashayekhi, Michael Gick, Miroslaw Ferenc, Heinz Joachim Büttner, Franz-Josef Neumann
Background As technologies of percutaneous coronary intervention (PCI) for coronary chronic total occlusions (CTO) have improved, great uncertainty exists regarding patient selection and long-term benefit of CTO-PCI. Given that white blood cell (WBC) count has been associated with cardiovascular risk, we hypothesized that the latter might provide incremental prognostic value in patients undergoing CTO-PCI. Methods and Results Our study population consisted of 1,262 consecutive patients (76.3% males, mean age of 67...
October 10, 2017: Thrombosis and Haemostasis
https://www.readbyqxmd.com/read/29044008/analysis-of-the-effect-of-paclitaxel-eluting-stents-and-paclitaxel-eluting-balloon-in-the-treatment-of-in-stent-restenosis
#11
Jiangtao Cheng, Chuanyu Gao, Yuhao Liu, Zhongmin Wang, Xiaohui Zheng, Datun Qi
To compare and analyze the effect and the safety of the paclitaxel-eluting stents and paclitaxel-eluting balloon in the treatment for in-stent rest enosis. 120 cases, who had been undergone percutaneous coronary intervention (PCI) in the Department of Cardiology of Henan Provincial People's Hospital from January 2012 to January 2014 were selected. All the patients were randomly treated with paclitaxel-eluting balloon or paclitaxel-eluting stents. The former were divided into different groups that named group A and the later group B...
July 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29043405/-focused-update-on-dual-antiplatelet-treatment-esc-guidelines-2017
#12
A Schäfer, J Bauersachs
Dual antiplatelet treatment (DAPT) is a cornerstone of maintenance medication of patients following elective percutaneous coronary interventions or an acute coronary syndrome (ACS), e. g. ST elevation myocardial infarction, non-ST elevation myocardial infarction and unstable angina. In recent years the inclusion of P2Y12 inhibition in addition to low-dose acetylsalicylic acid has been intensively debated. Following the introduction of the modern generation of drug-eluting stents for elective coronary interventions, the duration of the necessary DAPT has been clearly reduced...
October 17, 2017: Herz
https://www.readbyqxmd.com/read/29042400/thrombus-aspiration-for-st-segment-elevation-myocardial-infarction-in-modern-era-still-an-issue-of-debate
#13
REVIEW
Junhua Ge, Andreas Schäfer, Georg Ertl, Peter Nordbeck
The role of manual thrombus aspiration (TA) during primary percutaneous coronary intervention (PPCI) for acute ST-segment-elevation myocardial infarction has been a matter of intense research and debate now. Although recent randomized controlled clinical trials (notably TASTE [Thrombus Aspiration in ST-Elevation Myocardial Infarction in Scandinavia] and TOTAL [Trial of Routine Aspiration Thrombectomy With PCI Versus PCI Alone in Patients With STEMI]) do not supply evidence supporting the routine use of TA in patients with ST-segment-elevation myocardial infarction, manual TA remains a therapeutic option for interventional cardiologists when treating patients with substantial thrombus burden during PPCI...
October 2017: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29042383/health-education-for-patients-with-acute-coronary-syndrome-and-type-2-diabetes-mellitus-an-umbrella-review-of-systematic-reviews-and-meta-analyses
#14
Xian-Liang Liu, Yan Shi, Karen Willis, Chiung-Jung Jo Wu, Maree Johnson
OBJECTIVES: This umbrella review aimed to identify the current evidence on health education-related interventions for patients with acute coronary syndrome (ACS) or type two diabetes mellitus (T2DM); identify the educational content, delivery methods, intensity, duration and setting required. The purpose was to provide recommendations for educational interventions for high-risk patients with both ACS and T2DM. DESIGN: Umbrella review of systematic reviews and meta-analyses...
October 16, 2017: BMJ Open
https://www.readbyqxmd.com/read/29041876/-stress-echocardiography-in-the-assessment-of-long-term-outcomes-after-percutaneous-coronary-intervention-in-patients-with-stable-coronary-heart-disease
#15
A Y Karpov, M M Elkanova, N V Shitov, V U Botvina, V V Lopukhova, A M Saidova
AIM: To study the possibilities of stress echocardiography (EchoCG) in the assessment of clinical state of patients after percutaneous coronary intervention (PCI). MATERIAL AND METHODS: We included into this study 80 patients with stable ischemic heart disease. After preliminary examination, all patients underwent PCI. Stress EchoCG was carried out in 6 and 12 months after PCI. RESULTS: Clinical effect assessed in 12 months after revascularization was good in 90% of patients...
July 2017: Kardiologiia
https://www.readbyqxmd.com/read/29041001/hmgb1-expression-level-in-circulating-platelets-is-not-significantly-associated-with-outcomes-in-symptomatic-coronary-artery-disease
#16
Dominik Rath, Tobias Geisler, Meinrad Gawaz, Sebastian Vogel
BACKGROUND/AIMS: Platelets express high-mobility group box 1 (HMGB1), a damage-associated molecular pattern molecule (DAMP) that triggers thrombosis and inflammation when present in extracellular space. The role of platelet-derived HMGB1 in coronary artery disease (CAD) remains unexplored. METHODS: In a cohort study, we measured the expression of HMGB1 on the surface of circulating platelets in 183 patients with symptomatic CAD (stable CAD: n=80, acute coronary syndrome, ACS: n=103) at the time of percutaneous coronary intervention...
October 17, 2017: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/29040663/heart-type-fatty-acid-binding-protein-h-fabp-and-highly-sensitive-troponin-t-hstnt-as-markers-of-myocardial-injury-and-cardiovascular-events-in-elective-percutaneous-coronary-intervention-pci
#17
M Connolly, J Shand, M Kinnin, I Menown, M J Kurth, J Lamont, D Mc Eneaney
OBJECTIVES: To assess the prognostic value of biomarkers of myocardial injury following elective percutaneous coronary intervention (PCI). BACKGROUND: Type 4a myocardial infarction (MI) occurs when myocardial injury is combined with either symptoms suggestive of myocardial ischaemia, new left bundle branch block, angiographic loss of patency of a major artery or imaging suggestive of new loss of myocardium. Myocardial injury is defined as a rise of > 5 x 99th upper reference limit (URL) of 14ng/L (i...
October 10, 2017: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/29040445/rationale-and-design-of-the-effectiveness-of-lower-maintenance-dose-of-ticagrelor-early-after-myocardial-infarction-electra-pilot-study
#18
Jacek Kubica, Piotr Adamski, Katarzyna Buszko, Aldona Kubica, Wiktor Kuliczkowski, Tomasz Fabiszak, Bernd Jilma, Dimitrios Alexopoulos, Przemyslaw Paciorek, Eliano P Navarese
BackgroundThe degree and time course of platelet inhibition using ticagrelor can vary during the acute phase and the following stable period after acute myocardial infarction (AMI). The optimal level of platelet inhibition during the various stages of AMI remains an open question. The aim of the current study is to compare the antiplatelet efficacy of two ticagrelor maintenance dose regimens (60 mg b.i.d. vs 90 mg b.i.d.) in stable patients following an initial strategy with ticagrelor 90 mg b.i.d. during the first month after AMI...
October 10, 2017: European Heart Journal. Cardiovascular Pharmacotherapy
https://www.readbyqxmd.com/read/29039972/targeted-identification-of-adverse-events-in-coronary-artery-disease-patients-based-on-patient-reported-outcomes
#19
Jari Heiskanen, Anna-Maija Tolppanen, Janne Martikainen, Juha Hartikainen, Heikki Miettinen, Mikko Hippeläinen, Risto P Roine
AIM: Can focusing the adverse events search to patients with poor patient-reported outcome help in targeting adverse event detection? PATIENTS & METHODS: Coronary artery revascularization patients of the Kuopio University Hospital from June 2012 to August 2014 categorized into those with clinically significant improvement (15D score change ≥0.015, n = 81) or deterioration (change ≥-0.015, n = 64) in post-intervention health-related quality of life. RESULTS: Major complications (27 vs 9%, p = 0...
October 17, 2017: Journal of Comparative Effectiveness Research
https://www.readbyqxmd.com/read/29039827/-impact-of-hyperglycemia-on-the-results-of-percutaneous-coronary-interventions-in-patients-with-acute-st-segment-elevation-myocardial-infarction
#20
I S Bessonov, V A Kuznetsov, Yu V Potolinskaya, I P Zyrianov, S S Sapozhnikov
AIM: To investigate the impact of hyperglycemia on the results of percutaneous coronary interventions (PCIs) in patients with acute ST-segment elevation myocardial infarction (ASTEMI). SUBJECTS AND METHODS: A study group consisted of 511 patients with hyperglycemia (blood glucose level (BGL) ≥7.77 mmol/L) who underwent primary PCIs in the period from 2005 to 2015. A comparison group included 579 patients (BGL ≥7.77 mmol/L). RESULTS: Assessment of the results of hospital interventions revealed that the mortality rates in patients with hyperglycemia proved to be higher than in those with normal BGL (6...
2017: Terapevticheskiĭ Arkhiv
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