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https://www.readbyqxmd.com/read/29917255/an-avatar-based-education-application-to-improve-patients-knowledge-of-and-response-to-heart-attack-symptoms-a-pragmatic-randomized-controlled-trial-protocol
#1
Jintana Tongpeth, Huiyun Du, Robyn Clark
AIM: To evaluate the effectiveness of an interactive, avatar based education application to improve knowledge of and response to heart attack symptoms in people who are at risk of a heart attack. BACKGROUND: Poor knowledge of heart attack symptoms is recognised as a significant barrier to timely medical treatment. Numerous studies have demonstrated that technology can assist in patient education to improve knowledge and self-care. DESIGN: A single-center, non-blinded, two parallel groups, pragmatic randomized controlled trial...
June 19, 2018: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/29916769/self-management-of-cardiac-pain-in-women-a-meta-summary-of-the-qualitative-literature
#2
Ann Kristin Bjørnnes, Monica Parry, Marit Leegaard, Ana Patricia Ayala, Erica Lenton, Paula Harvey, Judith McFetridge-Durdle, Michael H McGillion, Jennifer Price, Jennifer Stinson, Judy Watt-Watson
Symptom recognition and self-management is instrumental in reducing the number of deaths related to coronary artery disease (CAD) in women. The purpose of this study was to synthesize qualitative research evidence on the self-management of cardiac pain and associated symptoms in women. Seven databases were systematically searched, and the concepts of the Individual and Family Self-Management Theory were used as the framework for data extraction and analysis. Search strategies yielded 22,402 citations, from which 35 qualitative studies were included in a final meta-summary, comprising data from 769 participants, including 437 (57%) women...
June 1, 2018: Qualitative Health Research
https://www.readbyqxmd.com/read/29915905/antithromboembolic-strategies-for-patients-with-atrial-fibrillation-undergoing-percutaneous-coronary-intervention
#3
REVIEW
Ayesha Ather, Benjamin Laliberte, Brent N Reed, Ashley Schenk, Kristin Watson, Sandeep Devabhakthuni, Vincent Y See
We set out to synthesize available data on antithrombotic strategies for patients with atrial fibrillation (AF) undergoing percutaneous coronary intervention (PCI), with a focus on triple antithrombotic therapy (triple therapy [TT]; dual antiplatelet therapy plus an anticoagulant) versus dual therapy (DT; one antiplatelet agent and an anticoagulant). We searched OVID MEDLINE and PubMed from January 2005 to September 2017 using the search terms oral anticoagulant, triple therapy, dual therapy, acute coronary syndrome, percutaneous coronary intervention, and atrial fibrillation (limited to randomized controlled trials, observational studies, English language, minimum 6-12 months of follow-up, minimum 100 human patients)...
June 19, 2018: American Journal of Cardiovascular Drugs: Drugs, Devices, and Other Interventions
https://www.readbyqxmd.com/read/29915535/the-therapeutic-efficacy-of-danhong-injection-combined-with-percutaneous-coronary-intervention-in-acute-coronary-syndrome-a-systematic-review-and-meta-analysis
#4
REVIEW
Jun-Bo Zou, Xiao-Fei Zhang, Jing Wang, Fang Wang, Jiang-Xue Cheng, Fang-Yan Yang, Xiao Song, Yu Wang, Yu-Lin Liang, Ya-Jun Shi
Background: Percutaneous coronary intervention (PCI) is widely used in treatment of acute coronary syndrome (ACS) clinically. It is believed that Danhong injection (DHI) extracted from salviae miltiorrhizae and flos carthami combined with PCI could increase the therapeutic efficacy on ACS. We provide an updated meta-analysis with detailed information on combination of DHI and PCI therapy. Materials and Methods: Electronic databases were searched for appropriate articles without language limitations on key words before October 22, 2017...
2018: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29915211/prognostic-value-of-culprit-artery-double-stranded-dna-in-st-segment-elevated-myocardial-infarction
#5
Xiqiang Wang, Dandan Yang, Jing Liu, Xiude Fan, Aiqun Ma, Ping Liu
The double-stranded DNA (dsDNA) which is scaffold of neutrophil extracellular traps (NETs) has been reported to be associated with the occurrence of major adverse cardiovascular events (MACEs) in patients with coronary atherosclerosis. However, the relationship between the dsDNA and the occurrence of MACEs in patients with ST-segment elevated myocardial infarction (STEMI) remains unclear. In this study, 142 consecutive STEMI patients were admitted to medical institutions. Blood from the infarct-related coronary artery (ICA) and peripheral artery (PA) were obtained during percutaneous coronary intervention...
June 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29914573/stent-thrombosis-associated-with-drug-eluting-stents-on-addition-of-cilostazol-to-the-standard-dual-antiplatelet-therapy-following-percutaneous-coronary-intervention-a-systematic-review-and-meta-analysis-of-published-randomized-controlled-trials
#6
Feng Huang
BACKGROUND: In this analysis, we aimed to systematically compare stent thrombosis (ST) and its different subtypes following treatment with DAPT (aspirin + clopidogrel) versus TAPT (aspirin + clopidogrel + cilostazol). METHODS: Studies were included if: they were randomized controlled trials (RCTs) comparing TAPT (cilostazol + aspirin + clopidogrel) with DAPT (aspirin + clopidogrel); they reported ST or its subtype including definite, probable, acute, sub-acute and late ST as their clinical outcomes...
June 18, 2018: BMC Pharmacology & Toxicology
https://www.readbyqxmd.com/read/29914380/vasodilator-stimulated-phosphoprotein-guided-clopidogrel-maintenance-therapy-reduces-cardiovascular-events-in-atrial-fibrillation-patients-requiring-anticoagulation-therapy-and-scheduled-for-percutaneous-coronary-intervention-a-prospective-cohort-study
#7
Chaoyue Hu, Xumin Zhang, Yonghua Liu, Yang Gao, Xiaohong Zhao, Hua Zhou, Yu Luo, Yaling Liu, Xiaodong Wang
BACKGROUND: In a previous study, we found that titrating clopidogrel maintenance doses (MDs) according to vasodilator-stimulated phosphoprotein (VASP) monitoring minimised the rate of major adverse cardiovascular and cerebral events (MACCE) after percutaneous coronary intervention (PCI) without increasing bleeding in patients with high on-treatment platelet reaction to clopidogrel. This study aimed to investigate whether VASP-guided clopidogrel MD could reduce thromboembolism and bleeding in atrial fibrillation (AF) patients requiring anticoagulation and scheduled for PCI...
June 18, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29913478/lipid-biomarkers-in-acute-myocardial-infarction-before-and-after-percutaneous-coronary-intervention-by-lipidomics-analysis
#8
Limin Feng, Jianzhou Yang, Wennan Liu, Qing Wang, Huijie Wang, Le Shi, Liyan Fu, Qiang Xu, Baohe Wang, Tian Li
BACKGROUND Reperfusion injury is one of the leading causes of myocardial cell death and heart failure. This study was performed to identify new candidate lipid biomarkers for the purpose of optimizing the diagnosis of myocardial ischemia reperfusion (I/R) injury, assessing the severity of myocardial I/R injury and trying to find the novel mechanism related to lipids. MATERIAL AND METHODS Forty patients who were diagnosed with ST-segment elevation myocardial infarction (STEMI) were randomly selected for this study...
June 18, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29912784/clinical-outcomes-in-nonagenarians-undergoing-a-percutaneous-coronary-intervention-data-from-the-orpki-polish-national-registry-2014-2016
#9
Tomasz Tokarek, Zbigniew Siudak, Artur Dziewierz, Tomasz Rakowski, Róża Krycińska, Andżelika Siwiec, Dariusz Dudek
BACKGROUND: Despite an increase in the proportion of nonagenarians in demographic structure, there is still a paucity of data on the utilization and outcome of percutaneous coronary interventions (PCIs) in this population. Also, very old patients are under-represented in randomized clinical trials and their treatment is still an emerging challenge. Thus, we sought to compare patient profiles and periprocedural outcomes of PCI in nonagenarians and patients younger than 90 years. PATIENTS AND METHODS: Data were based on the Polish National Registry of PCI (ORPKI)...
June 15, 2018: Coronary Artery Disease
https://www.readbyqxmd.com/read/29912783/impact-of-serum-lipoprotein-a-on-endothelium-dependent-coronary-vasomotor-response-assessed-by-intracoronary-acetylcholine-provocation
#10
Ahmed Mashaly, Seung-Woon Rha, Byoung G Choi, Man J Baek, Yang G Ryu, Se Y Choi, Jae K Byun, Kareem Abdelshafi, Yoonjee Park, Won Y Jang, Kim Woohyeun, Eun J Park, Jah Yeon Choi, Jin O Na, Cheol U Choi, Hong E Lim, Eung J Kim, Chang G Park, Hong S Seo
BACKGROUND: Lipoprotein(a) [Lp(a)] is an independent risk factor for atherosclerotic vascular disease. However, there are limited data regarding the impact of Lp(a) levels on the incidence and severity of endothelium-dependent coronary vasomotor response. PATIENTS AND METHODS: A total of 2416 patients without significant coronary artery lesion (<50% stenosis) by coronary angiography and underwent acetylcholine (ACh) provocation test were enrolled and categorized according to their serum Lp(a) level into four quartile groups: less than 6...
June 16, 2018: Coronary Artery Disease
https://www.readbyqxmd.com/read/29912429/oxygen-therapy-in-st-elevation-myocardial-infarction
#11
Robin Hofmann, Nils Witt, Bo Lagerqvist, Tomas Jernberg, Bertil Lindahl, David Erlinge, Johan Herlitz, Joakim Alfredsson, Rikard Linder, Elmir Omerovic, Oskar Angerås, Dimitrios Venetsanos, Thomas Kellerth, David Sparv, Jörg Lauermann, Neshro Barmano, Dinos Verouhis, Ollie Östlund, Leif Svensson, Stefan K James
Aims: To determine whether supplemental oxygen in patients with ST-elevation myocardial infarction (STEMI) impacts on procedure-related and clinical outcomes. Methods and results: The DETermination of the role of Oxygen in suspected Acute Myocardial Infarction (DETO2X-AMI) trial randomized patients with suspected myocardial infarction (MI) to receive oxygen at 6 L/min for 6-12 h or ambient air. In this pre-specified analysis, we included only STEMI patients who underwent percutaneous coronary intervention (PCI)...
June 14, 2018: European Heart Journal
https://www.readbyqxmd.com/read/29912422/age-and-outcomes-following-guided-de-escalation-of-antiplatelet-treatment-in-acute-coronary-syndrome-patients-undergoing-percutaneous-coronary-intervention-results-from-the-randomized-tropical-acs-trial
#12
Dirk Sibbing, Lisa Gross, Dietmar Trenk, Claudius Jacobshagen, Tobias Geisler, Martin Hadamitzky, Béla Merkely, Róbert Gábor Kiss, András Komócsi, Radoslaw Parma, Stephan B Felix, Franz-Josef Neumann, Jörg Hausleiter, Monika Baylacher, Lukasz Koltowski, Julinda Mehilli, Kurt Huber, Zenon Huczek, Dániel Aradi, Steffen Massberg
Aims: Guided de-escalation of P2Y12-inhibitor treatment was recently identified as an effective alternative treatment strategy in acute coronary syndrome (ACS) patients undergoing percutaneous coronary intervention. Safety and efficacy of this strategy may differ in relation to patient's age. This pre-specified analysis of the TROPICAL-ACS trial aimed to assess the impact of age on clinical outcomes following guided de-escalation of antiplatelet treatment in ACS patients. Methods and results: Patients were randomly assigned in a 1:1 fashion to either standard treatment with prasugrel for 12 months (control group) or to a guided de-escalation regimen (1 week prasugrel followed by 1 week clopidogrel and platelet function testing guided maintenance therapy with clopidogrel or prasugrel from day 14 after hospital discharge; guided de-escalation group)...
June 14, 2018: European Heart Journal
https://www.readbyqxmd.com/read/29912229/-balloon-assisted-tracking-technique-to-preserve-radial-access-during-percutaneous-coronary-intervention
#13
Giovanni Lorenzoni, Pierluigi Merella, Gavino Casu
Transradial access for cardiac catheterization and percutaneous coronary intervention is recommended by international guidelines to reduce vascular complications. Unfortunately, some factors such as female sex, shorter body surface area and older age, were found to be independent predictors of transradial cardiac catheterization failure. The balloon-assisted tracking technique is a smart trick to avoid crossover from radial to femoral access in case of spasm, tortuosity, or stenosis.
June 2018: Giornale Italiano di Cardiologia
https://www.readbyqxmd.com/read/29912023/implementing-same-day-discharge-following-percutaneous-coronary-intervention-a-process-evaluation
#14
Yingyan Chen, Frances Lin, Andrea Marshall
BACKGROUND: The safety and effectiveness of same day discharge (SDD) following percutaneous coronary intervention are well demonstrated; however, the uptake of this model of care is low. PURPOSE: The aim was to examine the effectiveness of implementing SDD using a process evaluation methodology. METHODS: This study was undertaken in a cardiac services department of a tertiary teaching hospital in southeast Queensland, Australia. It was anticipated before the implementation that 120 patients could be discharged the same day in a 6 months' time period...
June 14, 2018: Journal of Nursing Care Quality
https://www.readbyqxmd.com/read/29911764/acute-right-ventricular-myocardial-infarction-following-percutaneous-coronary-artery-intervention
#15
Dante Antonelli, Ehud Rozner, Yoav Turgeman
No abstract text is available yet for this article.
June 2018: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/29911392/remote-ischaemic-conditioning-for-myocardial-infarction-or-elective-pci-systematic-review-and-meta-analyses-of-randomised-trials
#16
Paul M Haller, Kris G Vargas, Maria C Haller, Edita Piackova, Johann Wojta, Mariann Gyöngyösi, Bernard J Gersh, Attila Kiss, Bruno K Podesser, Kurt Huber
BACKGROUND: The efficacy of remote ischaemic conditioning in clinical trials of ST-segment elevation myocardial infarction (STEMI) or elective percutaneous coronary intervention is controversial. We aimed to systematically review and meta-analyse whether remote ischaemic conditioning reduces myocardial damage in those patients. METHODS: We searched PubMed, Embase and Web of Science from inception until December 2017 for randomised clinical trials evaluating remote ischaemic conditioning versus a control group...
June 1, 2018: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/29910847/dissolved-oxygen-scavenging-by-acoustic-droplet-vaporization-using-intravascular-ultrasound
#17
Kevin J Haworth, Bryan H Goldstein, Karla P Mercado-Shekhar, Rohan Srivastava, P Arunkumar, Haili Su, Ellena M Privitera, Christy K Holland, Andrew N Redington
Modification of dissolved gas content by acoustic droplet vaporization (ADV) has been proposed for several therapeutic applications. Reducing dissolved oxygen (DO) during reperfusion of ischemic tissue during coronary interventions could inhibit reactive oxygen species production and rescue myocardium. The objective of this study was to determine whether intravascular ultrasound (IVUS) can trigger ADV and reduce DO. Perfluoropentane emulsions were created using high-speed shaking and microfluidic manufacturing...
September 2017: IEEE International Ultrasonics Symposium: [proceedings]
https://www.readbyqxmd.com/read/29910807/the-lectin-pathway-of-complement-in-myocardial-ischemia-reperfusion-injury-review-of-its-significance-and-the-potential-impact-of-therapeutic-interference-by-c1-esterase-inhibitor
#18
REVIEW
Anneza Panagiotou, Marten Trendelenburg, Michael Osthoff
Acute myocardial infarction (AMI) remains a leading cause of morbidity and mortality in modern medicine. Early reperfusion accomplished by primary percutaneous coronary intervention is pivotal for reducing myocardial damage in ST elevation AMI. However, restoration of coronary blood flow may paradoxically trigger cardiomyocyte death secondary to a reperfusion-induced inflammatory process, which may account for a significant proportion of the final infarct size. Unfortunately, recent human trials targeting myocardial ischemia/reperfusion (I/R) injury have yielded disappointing results...
2018: Frontiers in Immunology
https://www.readbyqxmd.com/read/29910590/residual-syntax-score-ii-a-combination-of-the-assessment-of-the-revascularization-degree-and-the-clinical-evaluation-after-percutaneous-coronary-intervention
#19
Marouane Boukhris, Farouk Abcha, Salvatore D Tomasello, Simona Giubilato, Salvatore Azzarelli, Alfred R Galassi
No abstract text is available yet for this article.
April 2018: Journal of the Saudi Heart Association
https://www.readbyqxmd.com/read/29910589/residual-syntax-score-ii-and-complex-percutaneous-coronary-interventions
#20
Levent Cerit
No abstract text is available yet for this article.
April 2018: Journal of the Saudi Heart Association
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