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https://www.readbyqxmd.com/read/29694555/practical-implications-of-myocardial-viability-studies
#1
Wilter Dos Santos Ker, Thais Helena Peixoto Nunes, Marcelo Souto Nacif, Claudio Tinoco Mesquita
Many non-invasive methods, such as imaging tests, have been developed aiming to add a contribution to existing studies in estimating patients' prognosis after myocardial injury. This prognosis is proportional to myocardial viability, which is evaluated in coronary artery disease and left ventricular dysfunction patients only. While myocardial viability represents the likelihood of a dysfunctional muscle (resulting from decreased oxygen supply for coronary artery obstruction), hibernation represents post-interventional functional recovery itself...
March 2018: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/29694550/case-2-2018-coronary-cavitary-fistula-of-right-ventricular-coronary-artery-5-years-after-its-occlusion-by-interventional-catheterization
#2
Edmar Atik, Fidel Leal, Raul Arrieta
No abstract text is available yet for this article.
March 2018: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/29692936/safety-and-efficacy-of-triple-therapeutic-targets-with-rivaroxaban-after-acute-myocardial-infarction-complicated-by-left-ventricular-thrombi-in-a-case-of-nonvalvular-atrial-fibrillation
#3
Francesco Summaria, Gregory A Sgueglia, Fabrizio D'Errico, Antonella De Santis, Fabiana Piccioni, Gaetano Gioffrè, Achille Gaspardone
We present the complex case of a high-risk patient with nonvalvular atrial fibrillation, who experienced a non-ST elevation myocardial infarction complicated by left ventricular (LV) thrombi and underwent percutaneous coronary intervention with drug-eluting stent implantation. The patient was initially treated with short-term triple therapy including aspirin, clopidogrel, and rivaroxaban 15 mg/die. Following aspirin dropping one month after discharge, the patient continued on dual therapy with clopidogrel and rivaroxaban, and a clinical and imaging follow-up at 6 and 12 months confirmed the LV thrombi resolution, with no thromboembolic episodes and a good safety profile...
2018: Case Reports in Cardiology
https://www.readbyqxmd.com/read/29692396/pharmaco-invasive-strategy-an-attractive-alternative-for-management-of-st-elevation-myocardial-infarction-when-timely-primary-percutaneous-coronary-intervention-is-not-feasible
#4
EDITORIAL
https://www.readbyqxmd.com/read/29692371/obstructive-sleep-apnea-affecting-platelet-reactivity-in-patients-undergoing-percutaneous-coronary-intervention
#5
Xiao-Min Jiang, Xue-Song Qian, Xiao-Fei Gao, Zhen Ge, Nai-Liang Tian, Jing Kan, Jun-Jie Zhang
Background: The relationship between obstructive sleep apnea (OSA) and platelet reactivity in patients undergoing percutaneous coronary intervention (PCI) has not been defined. The present prospective, single-center study explored the relationship between platelet reactivity and OSA in patients with PCI. Methods: A total of 242 patients were finally included in the study. OSA was screened overnight by polysomnography. Platelet reactivity was assessed with a sequential platelet counting method, and the platelet maximum aggregation ratio (MAR) and average aggregation ratio were calculated...
May 5, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29692221/temporal-trends-in-secondary-prevention-in-myocardial-infarction-patients-discharged-with-left-ventricular-systolic-dysfunction-in-poland
#6
Mariusz Gasior, Marek Gierlotka, Łukasz Pyka, Tomasz Zdrojewski, Bogdan Wojtyniak, Krzysztof Chlebus, Piotr Rozentryt, Jacek Niedziela, Piotr Jankowski, Jadwiga Nessler, Grzegorz Opolski, Piotr Hoffman, Ewa Jankowska, Lech Polonski, Piotr Ponikowski
Background The proportion of patients discharged after myocardial infarction with left ventricular systolic dysfunction remains high and the prognosis is unfavourable. The aim of this study was to analyse the temporal trends in the treatment and outcomes of a nationwide cohort of patients. Methods and results Data from the Polish Registry of Acute Coronary Syndromes and Acute Myocardial Infarction in Poland Registry were combined to achieve complete information on inhospital course, treatment and outcomes. An all-comer population of patients discharged with left ventricular ejection fraction of 40% or less formed the sample population ( n = 28,080)...
January 1, 2018: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29691963/length-of-stay-following-percutaneous-coronary-intervention-an-expert-consensus-document-update-from-the-society-for-cardiovascular-angiography-and-interventions
#7
Arnold H Seto, Adhir Shroff, Mazen Abu-Fadel, James C Blankenship, Konstantinos Dean Boudoulas, Joaquin E Cigarroa, Gregory J Dehmer, Dmitriy N Feldman, Daniel M Kolansky, Kusum Lata, Rajesh V Swaminathan, Sunil V Rao
Since the publication of the 2009 SCAI Expert Consensus Document on Length of Stay Following percutaneous coronary intervention (PCI), advances in vascular access techniques, stent technology, and antiplatelet pharmacology have facilitated changes in discharge patterns following PCI. Additional clinical studies have demonstrated the safety of early and same day discharge in selected patients with uncomplicated PCI, while reimbursement policies have discouraged unnecessary hospitalization. This consensus update: (1) clarifies clinical and reimbursement definitions of discharge strategies, (2) reviews the technological advances and literature supporting reduced hospitalization duration and risk assessment, and (3) describes changes to the consensus recommendations on length of stay following PCI (Supporting Information Table S1)...
April 24, 2018: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29691803/association-of-beta-blockers-with-survival-on-patients-presenting-with-acs-treated-with-pci-a-propensity-score-analysis-from-the-bleemacs-registry
#8
Fabrizio D'Ascenzo, Dario Celentani, Alessandro Brustio, Alberto Grosso, Sergio Raposeiras-Roubín, Emad Abu-Assi, Jose Paulo Simao Henriques, Jorge Saucedo, José Ramón González-Juanatey, Stephen B Wilton, Wouter J Kikkert, Iván Nuñez-Gil, Albert Ariza-Sole, Xiantao Song, Dimitrios Alexopoulos, Christoph Liebetrau, Tetsuma Kawaji, Zenon Huczek, Shao-Ping Nie, Toshiharu Fujii, Luis Correia, Masa-Aki Kawashiri, José María García-Acuña, Danielle Southern, Emilio Alfonso, Belén Terol, Alberto Garay, Dongfeng Zhang, Yalei Chen, Ioanna Xanthopoulou, Neriman Osman, Helge Möllmann, Hiroki Shiomi, Michal Kowara, Krzysztof Filipiak, Xiao Wang, Yan Yan, Jing-Yao Fan, Yuji Ikari, Takuya Nakahayshi, Kenji Sakata, Masakazu Yamagishi, Oliver Kalpak, Sasko Kedev, Claudio Moretti, Maurizio D'Amico, Fiorenzo Gaita
PURPOSE: The aim was to evaluate prognostic value of beta-blocker (BB) administration in acute coronary syndromes (ACS) patients in the percutaneous coronary intervention (PCI) era. METHODS AND RESULTS: The BleeMACS project is a multicenter, observational, retrospective registry enrolling patients with ACS worldwide in 15 hospitals. Patients discharged with BB therapy were compared to those discharged without a BB before and after propensity score with matching...
April 24, 2018: American Journal of Cardiovascular Drugs: Drugs, Devices, and Other Interventions
https://www.readbyqxmd.com/read/29691767/prognostic-impact-of-final-kissing-balloon-technique-after-crossover-stenting-for-the-left-main-coronary-artery-from-the-aoi-lmca-registry
#9
Koji Nishida, Mamoru Toyofuku, Takeshi Morimoto, Masanobu Ohya, Yasushi Fuku, Hirooki Higami, Kyohei Yamaji, Hiromi Muranishi, Yuhei Yamaji, Daisuke Furukawa, Tomohisa Tada, Euihong Ko, Kazushige Kadota, Kenji Ando, Hiroki Sakamoto, Takashi Tamura, Kazuya Kawai, Takeshi Kimura
It is still uncertain whether the final kissing balloon technique (FKBT) is mandatory after crossover stenting for the left main coronary artery (LMCA). Assessing Optimal Percutaneous Coronary Intervention for LMCA (AOI-LMCA) registry, a 6-center retrospective registry, enrolled 1809 consecutive patients for LMCA stenting in Japan. In the present analysis, 5-year clinical outcomes were compared between non-FKBT (n = 160) and FKBT (n = 578) groups in patients treated with crossover stenting with drug-eluting stents from the LMCA to the left anterior descending artery...
April 24, 2018: Cardiovascular Intervention and Therapeutics
https://www.readbyqxmd.com/read/29691643/the-relationship-between-timing-of-prasugrel-pretreatment-and-in-stent-thrombus-immediately-after-percutaneous-coronary-intervention-for-acute-coronary-syndrome-an-optical-coherence-tomography-study
#10
Yosuke Katayama, Takashi Kubo, Yasushi Ino, Takeyoshi Kameyama, Yoshiki Matsuo, Hironori Kitabata, Kosei Terada, Hiroki Emori, Hiroshi Aoki, Akira Taruya, Kunihiro Shimamura, Shingo Ota, Atsushi Tanaka, Takeshi Hozumi, Takashi Akasaka
The optimal timing of pretreatment with prasugrel in percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS) is unclear. We used optical coherence tomography (OCT) to compare in-stent thrombus volume immediately after PCI between the administration of low-dose prasugrel (20 mg loading dose) at the time of diagnosis of ACS (early prasugrel: n = 34) and the administration of low-dose prasugrel immediately after diagnostic angiography prior to PCI for ACS (late prasugrel: n = 56). The durations between the administration of prasugrel and OCT in the early prasugrel group and late prasugrel group were 5...
April 24, 2018: Heart and Vessels
https://www.readbyqxmd.com/read/29691185/common-themes-in-patients-requiring-urgent-cardiothoracic-surgery-after-percutaneous-coronary-interventions-case-series-and-review-of-the-literature
#11
REVIEW
Saad Ezad, Trent D Williams, Jeremy Condon, Andrew J Boyle, Nicholas J Collins
Urgent cardiothoracic surgical intervention for the management of complications of percutaneous coronary intervention is uncommon in the stent era. Nonetheless, given increasing procedural complexity, in part reflecting an aging population, an ongoing hazard for urgent surgery remains. We sought to review the incidence and outcome of urgent cardiothoracic surgery in patients undergoing PCI in a contemporary cohort at a tertiary referral centre. The incidence of cardiothoracic intervention for PCI related complications was low at 0...
March 21, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29691182/staff-radiation-dose-during-percutaneous-coronary-procedures-role-of-adjunctive-protective-drapes
#12
Alessandro Sciahbasi, Alessandro Sarandrea, Stefano Rigattieri, Roberto Patrizi, Maria Cera, Cristian Di Russo, Francesco Perone, Vanessa Porretta, Silvio Fedele, Silvio Romano, Maria Penco, Giuseppe Ferraiuolo
BACKGROUND: The use of adjunctive protective drapes placed on the patient protects the operating physician from scatter radiation during percutaneous coronary procedures (PCP). No data are available on the effect of these drapes for staff members' radio-protection. PURPOSE: To evaluate staff radiation exposure during PCP and the effect of adjunctive protective drapes on dose reduction. METHODS: The RADIANT study (NCT01974453) is a prospective, observational study evaluating operator radiation exposure during PCP using electronic dosimeter...
April 6, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29691071/incidence-determinants-and-clinical-impact-of-definite-stent-thrombosis-on-mortality-in-women-from-the-win-des-collaborative-patient-level-pooled-analysis
#13
Laura S Kerkmeijer, Bimmer E Claessen, Usman Baber, Samantha Sartori, Jaya Chandrasekhar, Giulio G Stefanini, Gregg W Stone, P Gabriel Steg, Alaide Chieffo, Giora Weisz, Stephan Windecker, Ghada W Mikhail, Adnan Kastrati, Marie-Claude Morice, George D Dangas, Robbert J de Winter, Roxana Mehran
BACKGROUND: Predictors and clinical outcomes of stent thrombosis (ST) in women have not been well investigated. Present study aimed to identify predictors of definite ST and its impact on mortality in women undergoing percutaneous coronary intervention (PCI). METHODS: Patient-level data of women enrolled in 26 randomized trials of DES was pooled. The study population was stratified based on the presence or absence of definite ST. Cox proportional hazards models were used to determine the predictors of definite ST...
April 12, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29689569/microrna-223-regulates-cardiac-fibrosis-after-myocardial-infarction-by-targeting-rasa1
#14
Xiaoxiao Liu, Yifeng Xu, Yunfei Deng, Hongli Li
BACKGROUND/AIMS: Percutaneous coronary intervention reduces acute myocardial infarction (MI)-induced mortality to a great extent, but effective treatments for MI-induced cardiac fibrosis and heart failure are still lacking. MicroRNAs (miRNAs) play a variety of roles in cells and have thus been investigated extensively. MicroRNA-223 (miR-223) expression has been reported to be altered in post-MI heart failure in humans; however, the roles of miR-223 in MI remain unknown. Our study aimed to elucidate the roles of miR-223 in cardiac fibrosis...
April 19, 2018: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/29688904/chronic-total-occlusion-intervention-of-the-non-infarct-related-artery-in-acute-myocardial-infarction-patients-the-korean-multicenter-chronic-total-occlusion-registry
#15
Ji Young Park, Byoung Geol Choi, Seung-Woon Rha, Tae Soo Kang, Cheol Ung Choi, Cheol Woong Yu, Hyeon-Cheol Gwon, In-Ho Chae, Hyo-Soo Kim, Hun Sik Park, Seung-Hwan Lee, Moo-Hyun Kim, Seung-Ho Hur, Yangsoo Jang
BACKGROUND: The Korean chronic total occlusion (CTO) registry was collected prospectively from 26 cardiovascular centers since May 2007. The aim of this study is to investigate the impact of a successful staged percutaneous coronary intervention (PCI) of CTO lesions in acute myocardial infarction (AMI) patients on clinical outcomes. PATIENTS AND METHODS: Among 2813 patients who underwent a staged PCI because of CTO lesions, 422 (15%) patients underwent primary PCI because of AMI...
April 23, 2018: Coronary Artery Disease
https://www.readbyqxmd.com/read/29688419/clinical-impact-of-direct-stenting-and-interaction-with-thrombus-aspiration-in-patients-with-st-segment-elevation-myocardial-infarction-undergoing-percutaneous-coronary-intervention-thrombectomy-trialists-collaboration
#16
Karim D Mahmoud, Sanjit S Jolly, Stefan James, Vladimír Džavík, John A Cairns, Goran K Olivecrona, Henrik Renlund, Peggy Gao, Bo Lagerqvist, Ashraf Alazzoni, Sasko Kedev, Goran Stankovic, Brandi Meeks, Ole Frøbert, Felix Zijlstra
Aims: Preliminary studies suggest that direct stenting (DS) during percutaneous coronary intervention (PCI) may reduce microvascular obstruction and improve clinical outcome. Thrombus aspiration may facilitate DS. We assessed the impact of DS on clinical outcome and myocardial reperfusion and its interaction with thrombus aspiration among ST-segment elevation myocardial infarction (STEMI) patients undergoing PCI. Methods and results: Patient-level data from the three largest randomized trials on routine manual thrombus aspiration vs...
April 21, 2018: European Heart Journal
https://www.readbyqxmd.com/read/29688287/implications-of-coronary-artery-bypass-grafting-and-percutaneous-coronary-intervention-on-disease-progression-and-the-resulting-changes-to-the-physiology-and-pathology-of-the-native-coronary-arteries
#17
Jacqueline H Fortier, Giovanni Ferrari, David Glineur, Mario Gaudino, Richard E Shaw, Marc Ruel, Juan B Grau
Myocardial revascularization can be achieved through 2 different methods: coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI). Clinical trials comparing PCI and CABG generally use the composite end points of death, stroke, myocardial infarction and target vessel revascularization to determine superiority. Other effects of these interventions, including the preservation of normal coronary physiology, the response of the coronary tree to stressors and the response of the vessel wall to the revascularization intervention, are not routinely considered, but these may have significant implications for patients in the medium and long term...
April 23, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29688206/-exoprosthetic-repair-of-the-ascending-portion-of-the-aorta-midterm-results
#18
A M Cherniavskiĭ, D A Sirota, M M Liashenko, S A Al'sov, D S Khvan
The authors analyse herein their experience gained in performing the operation of exoprosthetic repair of the ascending portion of the aorta in patients presenting with an ascending aortic aneurysm. This is followed by assessing the results in the remote period. Over the period of follow up from 2012 to 2016 a total of 23 interventions were performed. The average duration of postoperative follow up amounted to 27±9.4 (2-40) months. In the remote period we managed to obtain the data for 20 (90.1%) patients...
2018: Angiologii︠a︡ i Sosudistai︠a︡ Khirurgii︠a︡, Angiology and Vascular Surgery
https://www.readbyqxmd.com/read/29688176/impact-of-bleeding-assessment-and-adjudication-methodology-on-event-rates-and-clinical-trial-outcomes-insights-from-the-horizons-ami-trial
#19
Ioanna Kosmidou, Gary S Mintz, Tannas Jatene, Monica Embacher, Björn Redfors, S Chiu Wong, Ovidiu Dressler, Roxana Mehran, Ori Ben-Yehuda, Paul L Jenkins, Gregg W Stone
AIMS: Bleeding is a major safety outcome in cardiovascular trials. The present study assessed the impact of the adjudication process of bleeding events on 3-year outcomes in the Harmonizing Outcomes with Revascularization and Stents in Acute Myocardial Infarction (HORIZONS-AMI) trial. METHODS AND RESULTS: HORIZONS-AMI enrolled 3,602 patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention. An independent CEC reviewed 445 potential bleeding events identified from 3 sources: 339 site-reported (SR), 35 CEC-identified, and 71 database (DB)-triggered events based on programmatic identification of a decline in hemoglobin of ≥3 g/dL or in hematocrit by ≥9%; of those, 383/445 (86...
April 24, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29687877/the-mechanism-of-exogenous-adiponectin-in-the-prevention-of-no-reflow-phenomenon-in-type-2-diabetic-patients-with-acute-myocardial-infarction-during-pci-treatment
#20
C-J Zhang, Y-Z Deng, Y-H Lei, J-B Zhao, W Wei, Y-H Li
OBJECTIVE: To investigate the mechanism of exogenous adiponectin in the prevention of no-reflow phenomenon in type 2 diabetic (T2DM) patients with acute myocardial infarction (AMI) during percutaneous coronary intervention (PCI) treatment. PATIENTS AND METHODS: 66 patients were randomly divided into control group and observation group, 33 cases in each group. According to the percutaneous coronary intervention (PCI) emergency treatment principle, patients from the control group were treated with an intracoronary injection of adenosine combined with a micro-pump intravenous infusion of tirofiban...
April 2018: European Review for Medical and Pharmacological Sciences
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