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Oral malodor

Atik Ramadhani, Miki Kawada-Matsuo, Hitoshi Komatsuzawa, Takahiko Oho
Hydrogen sulfide (H2S) is emitted from industrial activities, and several chemotrophs possessing Sox enzymes are used for its removal. Oral malodor is a common issue in the dental field and major malodorous components are volatile sulfur compounds (VSCs), including H2S and methyl mercaptan. Paracoccus pantotrophus is an aerobic, neutrophilic facultatively autotrophic bacterium that possesses sulfur-oxidizing (Sox) enzymes in order to use sulfur compounds as an energy source. In the present study, we cloned the Sox enzymes of P...
March 31, 2017: Microbes and Environments
Nao Suzuki, Takuya Higuchi, Masato Nakajima, Akie Fujimoto, Hiromitsu Morita, Masahiro Yoneda, Takashi Hanioka, Takao Hirofuji
Volatile sulfur compounds (VSCs) produced by oral anaerobes are the major compounds responsible for oral malodor. Enterococcus faecium WB2000 is recognized as an antiplaque probiotic bacterium. In this study, the effect of E. faecium WB2000 on VSC production by Porphyromonas gingivalis was evaluated, and the mechanism of inhibition of oral malodor was investigated. P. gingivalis ATCC 33277 was cultured in the presence of four lactic acid bacteria, including E. faecium WB2000. Subsequently, P. gingivalis ATCC 33277, W50, W83, and two clinical isolates were cultured in the presence or absence of E...
2016: International Journal of Dentistry
Bernardi Sara, Marzo Giuseppe, Continenza Maria Adelaide
OBJECTIVE: The interest in the study of the tongue papillary niches and the related biofilm has increased in recent years because they form a suitable source of periodontal microorganisms and are associated with development of halitosis. Tongue dorsum structure represents a factor favoring a particular and complex bacterial biofilm where periodontal pathogens are frequently found. The aim of this preliminary study was to associate the tongue papillary structure with the biofilm causing halitosis by means of a new clinical protocol...
June 2016: Acta Stomatologica Croatica
Eun-Song Lee, Hyun-Kyung Yim, Hyung-Suk Lee, Jong-Hoon Choi, Ho-Keun Kwon, Baek-Il Kim
No abstract text is available yet for this article.
August 1, 2016: Journal of Biomedical Optics
Jumpei Washio, Tamaki Ogawa, Keisuke Suzuki, Yosuke Tsukiboshi, Motohiro Watanabe, Nobuhiro Takahashi
Dental plaque metabolizes both carbohydrates and amino acids. The former can be degraded to acids mainly, while the latter can be degraded to various metabolites, including ammonia, acids and amines, and associated with acid-neutralization, oral malodor and tissue inflammation. However, amino acid metabolism in dental plaque is still unclear. This study aimed to elucidate what kinds of amino acids are available as metabolic substrates and how the amino acids are metabolized in supragingival plaque, by a metabolome analysis...
2016: Biomedical Research
Mehmet Emre Dinc, Aytug Altundag, Denizhan Dizdar, Mehmet Ozgur Avincsal, Ethem Sahin, Seckin Ulusoy, Ceki Paltura
OBJECTIVES: Although most specialists in otorhinolaryngology and pediatrics find halitosis to be a common problem in children with adenoid hypertrophy, there are no objective data on this topic in the literature. Whether adenoid hypertrophy is a risk factor for halitosis or whether halitosis is a sign of adenoid hypertrophy remains unclear. Thus, the aim of this study was to investigate whether children diagnosed with adenoid hypertrophy have a higher probability of halitosis than do children in the normal population and whether adenoidectomy can decrease oral malodor...
September 2016: International Journal of Pediatric Otorhinolaryngology
N Suzuki, A Fujimoto, M Yoneda, T Watanabe, T Hirofuji, T Hanioka
BACKGROUND: Dryness of the oral cavity is considered one cause of oral malodor. However, it is unclear which of the factors regulating the wetness of the oral cavity are involved in oral malodor development. This study investigated the effects of salivary flow and oral mucosal moisture on oral malodor. METHODS: The study population comprised 119 patients (48 men and 71 women, mean age of 50.6 ± 15.4 years) with complaint of oral malodor. After the oral malodor level had been evaluated by the organoleptic test and gas chromatography, the rates of stimulated saliva and resting saliva and the moisture levels of the tongue and buccal mucosa were measured...
2016: BMC Oral Health
Edidiong Ntuen Kaminska, Freda Sansaricq, Vesna Petronic-Rosic
A 58-year-old woman with a 31-year history of Hailey-Hailey (HH) disease that was refractory to treatment with mycophenolate mofetil, cyclosporine, dapsone, sulfasalazine, topical/oral antibiotics, and topical/oral steroids presented for alternative treatment options. Active erythematous, malodorous, eroded, and crusted plaques were present in the axillae, inframammary region, groin, and back (Figure 1). The patient had an undulant course, with acute exacerbations and partial remissions. During a 3-year period, she was prescribed oral methotrexate at a dose of 10 mg to 15 mg per week with daily oral folic acid (1 mg) supplementation, except on the day she took methotrexate...
2016: Skinmed
Trent L Outhouse, Rashad Al-Alawi, Zbys Fedorowicz, James V Keenan
No abstract text is available yet for this article.
2016: Cochrane Database of Systematic Reviews
Isabelle C Jeusette, Aurora Mateo Román, Celina Torre, Josep Crusafont, Nuria Sánchez, Maria C Sánchez, Leire Pérez-Salcedo, David Herrera
OBJECTIVE To determine whether consumption of a single dental treat with specific mechanical properties and active ingredients would provide a 24-hour effect on dental plaque bacteria and halitosis in dogs. ANIMALS 10 dogs of various breeds from a privately owned colony that had received routine dental scaling and polishing 4 weeks before the study began. PROCEDURES Dogs were randomly assigned to receive 1 placebo or dental treat first. A 4-week washout period was provided, and then dogs received the opposite treatment...
June 2016: American Journal of Veterinary Research
Vandita Mishra, Leena Shettar, Mahesh Bajaj, Abhishek Savir Math
OBJECTIVES: Despite the adverse effects of chlorhexidine (CHX) in the oral cavity, it is still the most commonly prescribed mouthrinse for halitosis control due to its excellent results. The purpose of this study was to compare the efficacy of a mouthrinse with herbal formulation for halitosis control with 0.2% CHX gluconate containing rinse and to simultaneously assess adverse effects caused by the herbal mouthrinse if any. MATERIALS AND METHODS: Ninety-six systemically healthy subjects with chronic generalized gingivitis were recruited in the study and divided into three groups receiving 0...
April 2016: Journal of International Society of Preventive & Community Dentistry
Xi Chen, Yu Zhang, Hai-Xia Lu, Xi-Ping Feng
OBJECTIVE: To investigate the factors associated with halitosis in Chinese white-collar employees. MATERIALS AND METHODS: Subjects in three randomly selected office buildings in Shanghai, China, were enrolled in this cross-sectional study using cluster random sampling. Oral malodor was assessed by measuring volatile sulfur compounds (VSCs) with a portable sulfide monitor. Subjects' oral health, including dental caries, periodontal status, and tongue coating, was evaluated clinically...
2016: PloS One
Soumya Penala, Butchibabu Kalakonda, Krishnajaneya Reddy Pathakota, Avula Jayakumar, Pradeep Koppolu, Bolla Vijaya Lakshmi, Ruchi Pandey, Ashank Mishra
OBJECTIVE: Periodontitis is known to have multifactorial etiology, involving interplay between environmental, host and microbial factors. The current treatment approaches are aimed at reducing the pathogenic microorganisms. Administration of beneficial bacteria (probiotics) has emerged as a promising concept in the prevention and treatment of periodontitis. Thus, the aim of the present study is to evaluate the efficacy of the local use of probiotics as an adjunct to scaling and root planing (SRP) in the treatment of patients with chronic periodontitis and halitosis...
April 2016: Journal of Research in Pharmacy Practice
Megumi Futamura-Masuda, Mami Yokota-Honda, Takuya Anraku, Kanae Nakanishi, Kazuya Murata, Tetsuro Shinada, Hideaki Matsuda
Asiasarum root (roots and rhizome of Asiasarum sieboldii or A. heterotropoides var. mandshuricum) has been frequently used in traditional Chinese medicinal formulas for the management of oral malodor syndrome caused by periodontal disease. However, there are no scientific reports concerning these effects and the mechanism of action. The objective of this study was to examine the inhibitory effects of Asiasarum root and its constituents on oral malodor syndrome and periodontal disease. A 50% ethanolic extract of Asiasarum root (AR-ext) showed L-methionine γ-lyase (METase) inhibitory activity at a concentration of 200 µg/mL, and inhibited interleukin (IL)-1β-stimulated matrix metalloproteinase (MMP)-1 secretion from human gingival fibroblasts (HGFs) at a concentration of 10 and 50 µg/mL without cytotoxic effects...
2016: Biological & Pharmaceutical Bulletin
Ömür Dereci, Mükerrem Hatipoğlu, Alper Sindel, Sinan Tozoğlu, Kemal Üstün
BACKGROUND: This study aims to evaluate the efficacy of Er,Cr:YSGG laser assisted periodontal therapy on the reduction of oral malodor and periodontal disease. METHODS: Sixty patients with chronic periodontitis were included in the study and allocated into two groups each containing 30 patients. The study was planned in a double blind fashion. Conventional periodontal therapy was performed in group 1 and conventional periodontal therapy was performed in association with Er,Cr:YSGG application in group 2...
May 4, 2016: Head & Face Medicine
Uditi Kapoor, Gaurav Sharma, Manish Juneja, Archna Nagpal
Halitosis or oral malodor is an offensive odor originating from the oral cavity, leading to anxiety and psychosocial embarrassment. A patient with halitosis is most likely to contact primary care practitioner for the diagnosis and management. With proper diagnosis, identification of the etiology and timely referrals certain steps are taken to create a successful individualized therapeutic approach for each patient seeking assistance. It is significant to highlight the necessity of an interdisciplinary method for the treatment of halitosis to prevent misdiagnosis or unnecessary treatment...
April 2016: European Journal of Dentistry
Sreedevi Dharman, Muthukrishnan Arvind
Darier's disease, also known as keratosis follicularis, is a rare autosomal dominant genodermatosis, manifesting clinically as hyperkeratotic, firm papule that predominates in the seborrheic areas and flexures with accompanying nail abnormalities. Heat, sweating, sunlight, and stress are exacerbating factors of the lesion. The oral lesions are asymptomatic and comprise multiple white papules in the buccal mucosa and hard palate, giving a cobblestone appearance, and it is characterized histologically by loss of desmosomal adhesion and abnormal keratinization resulting in mucocutaneous abnormalities...
April 2016: Journal of the Indian Society of Pedodontics and Preventive Dentistry
B Nandlal, P Shahikumar, B S Avinash, P K Sreenivasan, R Subramanyam
OBJECTIVE: This clinical study compared the effects of an antibacterial regimen, comprising a triclosan toothpaste and a 0.075% cetylpyridinium chloride (CPC) mouthrinse, on malodor, self-reported malodor, and oral hygiene measures such as dental plaque, gingivitis, and bleeding relative to brushing with a fluoride toothpaste. MATERIALS AND METHODS: At baseline, 36 subjects were evaluated for malodor (9-point organoleptic scale [OLT]), dental plaque (Turesky modification of Quigley-Hein; PI), gingivitis (Lφe-Silness; GI) and bleeding (Ainamo and Bay; BI) and randomized to (1) tooth brushing with fluoride toothpaste, or (2) a regimen comprising tooth brushing with a triclosan toothpaste and mouth rinsing with CPC mouthrinse...
January 2016: Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research
Sophie De Geest, Isabelle Laleman, Wim Teughels, Christel Dekeyser, Marc Quirynen
Bad breath (halitosis) is an important social complaint. In most cases (≥90%), the cause of halitosis can be found within the oral cavity. Under this circumstance, the term oral malodor applies. It affects both healthy and periodontally diseased individuals. Oral malodor is mainly caused by a microbial degradation of both sulfur-containing and nonsulfur-containing amino acids into volatile, bad-smelling gases. Anaerobic gram-negative bacteria, the same species that have been linked to periodontal diseases, are especially involved in this process, explaining why clinicians often associate oral malodor with periodontitis...
June 2016: Periodontology 2000
Yuki Iwamura, Jun-Ichiro Hayashi, Takashi Sato, Sota Sato, Taeko Murakami, Takeki Fujimura, Yasuyuki Sasaki, Kosuke Okada, Eri Takahashi, Takeshi Kikuchi, Makoto Aino, Toshihide Noguchi, Yoshihiro Shimazaki, Akio Mitani, Mitsuo Fukuda
The oropharyngeal area can be a source of halitosis. However, the relationship between healthy tonsillar microbiota and halitosis is poorly understood. We conducted a pilot clinical study to clarify the effect of gargling with an antiseptic agent on tonsillar microbiota in patients with halitosis. Twenty-nine halitosis patients who did not have otolaryngologic disease or periodontitis were assigned randomly to one of three groups: benzethonium chloride (BZC) gargle; placebo gargle; no gargle. Concentrations of volatile sulfur compounds (VSCs) in mouth air, the organoleptic score (ORS) and tongue-coating score (TCS) were measured before and after testing...
2016: Journal of Oral Science
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