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https://www.readbyqxmd.com/read/29456811/-in-vivo-activity-assessment-of-some-tanacetum-species-used-as-traditional-wound-healer-along-with-identification-of-the-phytochemical-profile-by-a-new-validated-hplc-method
#1
Serkan Özbilgin, Esra Küpeli Akkol, Burçin Ergene Öz, Mert Ilhan, Gülçin Saltan, Özlem Bahadır Acıkara, Mehmet Tekin, Hikmet Keleş, Ipek Süntar
Objectives: Tanacetum species are traditionally used as insecticide, and externally wound healer as well as for anti-inflammatory and antihistaminic properties. The in vivo wound-healing and anti-inflammatory potential of four Tanacetum species, Tanacetum argenteum (Lam.) Willd. subsp. argenteum (TA) , Tanacetum heterotomum (Bornm.) Grierson (TH), Tanacetum densum (Lab.) Schultz Bip. subsp. sivasicum (TD), and Tanacetum vulgare L. (TV) was investigated. Materials and Methods: The chloroform (CHCl3 ) and methanol:water (80:20) extracts were prepared from the aerial parts of each plant...
February 2018: Iranian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/29456384/tea-polyphenols-and-prevention-of-epigenetic-aberrations-in-cancer
#2
REVIEW
Arundhati Bag, Niladri Bag
Tea polyphenols are secondary metabolites of tea plants and are well known for beneficial health effects. They can protect from a variety of illnesses including cancers. Tea polyphenols can prevent cancer by modulating epigenetic aberrations taking place in DNA methylation, histone modifications, and micro-RNAs. By altering these epimutations, they regulate chromatin dynamics and expression of genes those induce or suppress cancer formation. However, majority of the studies in existing literature are carried out for green tea polyphenols rather than black tea polyphenols despite the fact that black tea is the most commonly consumed form of tea (78%) followed by green tea (20%) and other forms of tea...
January 2018: Journal of Natural Science, Biology, and Medicine
https://www.readbyqxmd.com/read/29453255/endophyte-mediated-modulation-of-defense-responsive-genes-and-systemic-resistance-in-withania-somnifera-l-dunal-under-alternaria-alternata-stress
#3
Aradhana Mishra, Satyendra Pratap Singh, Sahil Mahfooz, Surendra Pratap Singh, Arpita Bhattacharya, Nishtha Mishra, C S Nautiyal
Endophytes have been explored to perform an important role in plant health. However, their effects on the host physiological function and disease management remains elusive. The present study was aimed to assess the potential of endophytes singly as well as in combination on various physiological parameters and systemic defense mechanism against Alternaria alternata in Withania somnifera (L.) Dunal. Seed priming with endophytic Bacillus amyloliquefaciens and Pseudomonas fluorescens individually and in combination demonstrated enhanced vigor index and germination rate...
February 16, 2018: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/29453089/botanical-essential-oils-and-uses-as-mosquitocides-and-repellents-against-dengue
#4
REVIEW
Muthiah Chellappandian, Prabhakaran Vasantha-Srinivasan, Sengottayan Senthil-Nathan, Sengodan Karthi, Annamalai Thanigaivel, Athirstam Ponsankar, Kandaswamy Kalaivani, Wayne B Hunter
Plants naturally produce bioactive compounds along with many secondary metabolites which serve as defensive chemical against herbivorers including insect pests. One group of these phytochemicals are the 'Essential Oils' (EO's), which possess an extensive range of biological activity especially insecticidal and insect repellents. This review provides a comprehensive viewpoint on potential modes of action of biosafety plant derived Essential Oils (EO's) along with their principal chemical derivatives against larvae and adult mosquito vectors of dengue virus...
February 13, 2018: Environment International
https://www.readbyqxmd.com/read/29452904/leaf-nodule-symbiosis-function-and-transmission-of-obligate-bacterial-endophytes
#5
REVIEW
Marta Pinto-Carbó, Karl Gademann, Leo Eberl, Aurelien Carlier
Various plant species establish intimate symbioses with bacteria within their aerial organs. The bacteria are contained within nodules or glands often present in distinctive patterns on the leaves, and have been used as taxonomic marker since the early 20th century. These structures are present in very diverse taxa, including dicots (Rubiaceae and Primulaceae) and monocots (Dioscorea). The symbionts colonize the plants throughout their life cycles and contribute bioactive secondary metabolites to the association...
February 13, 2018: Current Opinion in Plant Biology
https://www.readbyqxmd.com/read/29452376/the-vacuolar-transportome-of-plant-specialized-metabolites
#6
Rita de Brito Francisco, Enrico Martinoia
The plant vacuole is a cellular compartment that is essential to plant development and growth. Often plant vacuoles accumulate specialized metabolites, also called secondary metabolites, which constitute functionally and chemically diverse compounds that exert in planta many essential functions and improve the plant's fitness. These metabolites provide for example chemical defence against herbivorous and pathogens or chemical attractants (colour and fragrance) to attract pollinators. The chemical composition of the vacuole is dynamic and is altered during development and as a response to environmental changes...
February 14, 2018: Plant & Cell Physiology
https://www.readbyqxmd.com/read/29449610/phaeophleospora-vochysiae-savi-glienke-sp-nov-isolated-from-vochysia-divergens-found-in-the-pantanal-brazil-produces-bioactive-secondary-metabolites
#7
Daiani C Savi, Khaled A Shaaban, Francielly Maria Wilke Ramos Gos, Larissa V Ponomareva, Jon S Thorson, Chirlei Glienke, Jürgen Rohr
Microorganisms associated with plants are highly diverse and can produce a large number of secondary metabolites, with antimicrobial, anti-parasitic and cytotoxic activities. We are particularly interested in exploring endophytes from medicinal plants found in the Pantanal, a unique and widely unexplored wetland in Brazil. In a bio-prospecting study, strains LGMF1213 and LGMF1215 were isolated as endophytes from Vochysia divergens, and by morphological and molecular phylogenetic analyses were characterized as Phaeophleospora vochysiae sp...
February 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29447216/genome-mining-of-streptomyces-scabrisporus-nf3-reveals-symbiotic-features-including-genes-related-to-plant-interactions
#8
Corina Diana Ceapă, Melissa Vázquez-Hernández, Stefany Daniela Rodríguez-Luna, Angélica Patricia Cruz Vázquez, Verónica Jiménez Suárez, Romina Rodríguez-Sanoja, Elena R Alvarez-Buylla, Sergio Sánchez
Endophytic bacteria are wide-spread and associated with plant physiological benefits, yet their genomes and secondary metabolites remain largely unidentified. In this study, we explored the genome of the endophyte Streptomyces scabrisporus NF3 for discovery of potential novel molecules as well as genes and metabolites involved in host interactions. The complete genomes of seven Streptomyces and three other more distantly related bacteria were used to define the functional landscape of this unique microbe. The S...
2018: PloS One
https://www.readbyqxmd.com/read/29445362/microbial-flora-associated-with-the-halophyte-salsola-imbricate-and-its-biotechnical-potential
#9
Fehmida Bibi, Gary A Strobel, Muhammad I Naseer, Muhammad Yasir, Ahmed A Khalaf Al-Ghamdi, Esam I Azhar
Halophytes are associated with the intertidal forest ecosystem of Saudi Arabia and seemingly have an immense potential for yielding useful and important natural products. In this study we have aimed to isolate and characterize the endophytic and rhizospheric bacterial communities from the halophyte, Salsola imbricata , In addition these bacterial strains were identified and selected strains were further studied for bioactive secondary metabolites. At least 168 rhizspheric and endophytic bacteria were isolated and of these 22 were active antagonists against the oomycetous fungal plant pathogens, Phytophthora capsici and Pythium ultimum ...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29444667/in-vitro-antileishmanial-and-cytotoxicity-activities-of-essential-oils-from-haplophyllum-tuberculatum-a-juss-leaves-stems-and-aerial-parts
#10
Assia Hamdi, Joanne Bero, Claire Beaufay, Guido Flamini, Zohra Marzouk, Yvan Vander Heyden, Joelle Quetin-Leclercq
BACKGROUND: Plants used for traditional medicine produce diverse and complex secondary metabolites exhibiting various medicinal properties. The medicinal plant Haplophyllum tuberculatum is used by native people against malaria and parasitic infections. METHODS: In this study and in order to contribute for the search of new natural drugs for leishmaniasis, the essential oils of H. tuberculatum leaves, stems and aerial parts (leaves+stems) collected in two different periods, 2013 and 2015, and their components by GC/FID and GC/MS analyses were investigated...
February 14, 2018: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/29442047/comprehensive-phytochemical-characterization-of-st-john-s-wort-hypericum-perforatum-l-oil-macerates-obtained-by-different-extraction-protocols-via-analytical-tools-applicable-in-routine-control
#11
M Heinrich, R Daniels, F C Stintzing, D R Kammerer
The aim of the present study was to investigate the impact of crucial process parameters, i.e. of light and temperature conditions, during the preparation of St. John's wort (SJW, Hypericum perforatum L.) Arachis oil macerates. Extracts were prepared according to a standardized protocol over a period of 28 days. For this purpose, flowering tops of H. perforatum were macerated with Arachis oil (drug extract ratio, DERnative 1:4) under different light and temperature conditions. Spectrophotometric measurements were carried out to quantitate naphthodianthrones and to characterize extract color in the CIE L*C*h° system...
March 1, 2017: Die Pharmazie
https://www.readbyqxmd.com/read/29438895/piriformospora-indica-cell-wall-extract-as-the-best-elicitor-for-asiaticoside-production-in-centella-asiatica-l-urban-evidenced-by-morphological-physiological-and-molecular-analyses
#12
S Jisha, P R Gouri, K N Anith, K K Sabu
Vascular plants synthesise a multitude of organic molecules or phytochemicals, referred to as "secondary metabolites". These molecules are involved in a variety of roles in the life span of plants, ranging from structural ones to protection. Centella asiatica (L.) Urban has probably been used since prehistoric times and has been reported to have been used for various medicinal and cosmetic purposes. The plant contains several active constituents, of which the most important is asiaticoside, a triterpenoid. Asiaticoside content in C...
February 7, 2018: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/29438420/endogenous-salicylic-acid-shows-different-correlation-with-baicalin-and-baicalein-in-the-medicinal-plant-scutellaria-baicalensis-georgi-subjected-to-stress-and-exogenous-salicylic-acid
#13
Hu Su, Shurui Song, Xin Yan, Limin Fang, Bin Zeng, Youlin Zhu
Salicylic acid (SA) is synthesized via the phenylalanine lyase (PAL) and isochorismate synthase (ICS) pathways and can influence the stress response in plants by regulating certain secondary metabolites. However, the association between SA and particular secondary metabolites in the Chinese medicinal plant Scutellaria baicalensis Georgi is unclear. To elucidate the association between SA and the secondary metabolites baicalin and baicalein, which constitute the primary effective components of S. baicalensis, we subjected seedlings to drought and salt stress and exogenous SA treatment in a laboratory setting and tested the expression of PAL and ICS, as well as the content of free SA (FSA), total SA (TSA), baicalin, and baicalein...
2018: PloS One
https://www.readbyqxmd.com/read/29437777/trehalose-6-phosphate-regulates-photosynthesis-and-assimilate-partitioning-in-reproductive-tissue
#14
Maria Oszvald, Lucia F Primavesi, Cara A Griffiths, Jonathan Cohn, Shib Basu, Michael L Nuccio, Matthew J Paul
Transgenic maize expressing a rice trehalose phosphate phosphatase (TPP1) controlled by a rice MADS6 promoter active over the 2- to 3-week flowering period are higher yielding than wild type with or without drought during flowering. To better understand the mechanistic basis of the yield increase, we characterise gene expression and metabolite profiles in developing female reproductive tissue comprising florets, node, pith and shank and in leaves over the flowering period with and without drought. Using the β-glucuronidase reporter the MADS6 promoter activity was most closely linked to vasculature, particularly phloem companion cells in florets and pith consistent with largest decreases in trehalose 6-phosphate (T6P) levels (2-3 fold) in pith and florets...
February 6, 2018: Plant Physiology
https://www.readbyqxmd.com/read/29434251/transcriptome-analysis-in-tissue-sectors-with-contrasting-crocins-accumulation-provides-novel-insights-into-apocarotenoid-biosynthesis-and-regulation-during-chromoplast-biogenesis
#15
Oussama Ahrazem, Javier Argandoña, Alessia Fiore, Carolina Aguado, Rafael Luján, Ángela Rubio-Moraga, Mónica Marro, Cuauhtémoc Araujo-Andrade, Pablo Loza-Alvarez, Gianfranco Diretto, Lourdes Gómez-Gómez
Crocins, the red soluble apocarotenoids of saffron, accumulate in the flowers of Crocus species in a developmental and tissue-specific manner. In Crocus sieberi, crocins accumulate in stigmas but also in a distinct yellow tepal sector, which we demonstrate contains chromoplast converted from amyloplasts. Secondary metabolites were analysed by LC-DAD-HRMS, revealing the progressive accumulation of crocetin and crocins in the yellow sector, which were also localized in situ by Raman microspectroscopy. To understand the underlying mechanisms of crocin biosynthesis, we sequenced the C...
February 12, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29433083/inhibition-of-phospholipases-influences-the-metabolism-of-wound-induced-benzylisoquinoline-alkaloids-in-papaver-somniferum-l
#16
Veronika Jablonická, Jörg Ziegler, Zuzana Vatehová, Desana Lišková, Ingo Heilmann, Marek Obložinský, Mareike Heilmann
Benzylisoquinoline alkaloids (BIAs) are important secondary plant metabolites and include medicinally relevant drugs, such as morphine or codeine. As the de novo synthesis of BIA backbones is (still) unfeasible, to date the opium poppy plant Papaver somniferum L. represents the main source of BIAs. The formation of BIAs is induced in poppy plants by stress conditions, such as wounding or salt treatment; however, the details about regulatory processes controlling BIA formation in opium poppy are not well studied...
January 31, 2018: Journal of Plant Physiology
https://www.readbyqxmd.com/read/29431450/advanced-nmr-based-structural-investigation-of-glucosinolates-and-desulfoglucosinolates
#17
Nada Ibrahim, Ingrid Allart-Simon, Gina R De Nicola, Renato Iori, Jean-Hugues Renault, Patrick Rollin, Jean-Marc Nuzillard
Glucosinolates (GLs) constitute a class of plant secondary metabolites that are characteristic of the order Brassicales. They each contain a common hydrophilic moiety connected to a mostly hydrophobic side chain whose constitution is the most frequent structural variant. Their transformations by myrosinases lead to intensively studied and highly reactive compounds of biological relevancy. In other respects, the enzymatic desulfation of GLs produces derivatives (DS-GLs) that are useful for GL analysis. A collection of 31 compounds, GLs and DS-GLs, representing 17 different side chains was established in order to report accurate descriptions of the molecules' 1H-, 13C-, and 15N-NMR parameters...
February 12, 2018: Journal of Natural Products
https://www.readbyqxmd.com/read/29428967/consequences-of-interspecific-variation-in-defenses-and-herbivore-host-choice-for-the-ecology-and-evolution-of-inga-a-speciose-rainforest-tree
#18
REVIEW
Phyllis D Coley, María-José Endara, Thomas A Kursar
We summarize work on a speciose Neotropical tree genus, Inga (Fabaceae), examining how interspecific variation in anti-herbivore defenses may have evolved, how defenses shape host choice by herbivores and how they might regulate community composition and influence species radiations. Defenses of expanding leaves include secondary metabolites, extrafloral nectaries, rapid leaf expansion, trichomes, and synchrony and timing of leaf production. These six classes of defenses are orthogonal, supporting independent evolutionary trajectories...
February 10, 2018: Oecologia
https://www.readbyqxmd.com/read/29427428/mycotoxin-biosynthesis-and-central-metabolism-are-two-interlinked-pathways-in-fusarium-graminearum-as-demonstrated-by-the-extensive-metabolic-changes-induced-by-caffeic-acid-exposure
#19
Vessela Atanasova-Penichon, Laurie Legoahec, Stéphane Bernillon, Catherine Deborde, Mickaël Maucourt, Marie-Noelle Verdal-Bonnin, Laetitia Pinson-Gadais, Nadia Ponts, Annick Moing, Florence Richard-Forget
Fusarium graminearum is a major plant pathogen that causes devastating diseases of cereals and produces type B trichothecene mycotoxins (TCTB) in infected grains. A comprehensive understanding of the molecular and biochemical mechanisms underlying the regulation of TCTB biosynthesis is required for improving strategies to control the TCTB contamination of crops and ensuring that these strategies do not favor the production of other toxic metabolites by F. graminearum Elucidation of the association of TCTB biosynthesis with other central and specialized processes was the focus of this study...
February 2, 2018: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/29427347/from-robinia-pseudoacacia-l-nectar-to-acacia-monofloral-honey-biochemical-changes-and-variation-of-biological-properties
#20
Angelo Gismondi, Silvia De Rossi, Lorena Canuti, Silvia Novelli, Gabriele Di Marco, Laura Fattorini, Antonella Canini
BACKGROUND: Robinia pseudoacacia L. nectar and its derivative monofloral honey were systematically compared in this study, to understand how much the starting solution reflected the final product, after re-elaboration by Apis mellifera ligustica Spinola. RESULTS: Subjected to dehydration in the hive, nectar changed its water and sugar content when transformed in honey, as physicochemical and GC-MS analyses revealed. Spectrophotometrical measurements and HPLC-DAD characterization of 18 plant molecules demonstrated honey to be richer than nectar in secondary metabolites...
February 10, 2018: Journal of the Science of Food and Agriculture
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