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https://www.readbyqxmd.com/read/27634803/objective-measurements-of-energy-balance-are-associated-with-sleep-architecture-in-healthy-adults
#1
Andrea M Spaeth, David F Dinges, Namni Goel
STUDY OBJECTIVES: We objectively measured body composition, energy expenditure, caloric intake and sleep in a large, diverse sample of healthy men and women and determined how energy balance and diet associated with sleep physiology. METHODS: Healthy adults (n=50; 21-50y) participated in an in-laboratory study involving two baseline sleep nights (BL1-2, 10h time-in-bed/night, 2200h-0800h). Polysomnography was recorded on BL2. Demographic information, body composition and energy expenditure measurements were collected at study admittance and on BL1...
September 9, 2016: Sleep
https://www.readbyqxmd.com/read/27337421/nocturnal-wakefulness-as-a-previously-unrecognized-risk-factor-for-suicide
#2
Michael L Perlis, Michael A Grandner, Gregory K Brown, Mathias Basner, Subhajit Chakravorty, Knashawn H Morales, Philip R Gehrman, Ninad S Chaudhary, Michael E Thase, David F Dinges
OBJECTIVE: Suicide is a major public health problem and the 10th leading cause of death in the United States. The identification of modifiable risk factors is essential for reducing the prevalence of suicide. Recently, it has been shown that insomnia and nightmares significantly increase the risk for suicidal ideation, attempted suicide, and death by suicide. While both forms of sleep disturbance may independently confer risk, and potentially be modifiable risk factors, it is also possible that simply being awake at night represents a specific vulnerability for suicide...
June 2016: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/26951388/developing-biomarker-arrays-predicting-sleep-and-circadian-coupled-risks-to-health
#3
Janet M Mullington, Sabra M Abbott, Judith E Carroll, Christopher J Davis, Derk-Jan Dijk, David F Dinges, Philip R Gehrman, Geoffrey S Ginsburg, David Gozal, Monika Haack, Diane C Lim, Madalina Macrea, Allan I Pack, David T Plante, Jennifer A Teske, Phyllis C Zee
No abstract text is available yet for this article.
April 1, 2016: Sleep
https://www.readbyqxmd.com/read/26857059/short-term-variability-in-apnea-hypopnea-index-during-extended-home-portable-monitoring
#4
Bharati Prasad, Sarah Usmani, Alana D Steffen, Hans P A Van Dongen, Francis M Pack, Inna Strakovsky, Bethany Staley, David Dinges, Greg Maislin, Allan I Pack, Terri E Weaver
STUDY OBJECTIVES: Apnea-hypopnea index (AHI) is the primary measure used to confirm a diagnosis of obstructive sleep apnea (OSA). However, there may be significant night-to-night variability (NNV) in AHI, limiting the value of AHI in clinical decision-making related to OSA management. We examined short-term NNV in AHI and its predictors during home portable monitoring (PM). METHODS: Single center prospective observational study of patients (n = 84) with newly diagnosed OSA by polysomnography (PSG) AHI ≥ 5/h...
2016: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/26715404/determinants-of-behavioral-alertness-in-adults-with-heart-failure
#5
Ruth Masterson Creber, Victoria M Pak, Miranda Varrasse, David F Dinges, Joyce Wald, Barbara Riegel
STUDY OBJECTIVES: The primary objective of this study was to describe characteristics of sleep across the three domains of sleep quality, daytime sleepiness, and behavioral alertness in community-dwelling adults with heart failure. The secondary objective was to identify modifiable factors associated with behavioral alertness. METHODS: A sample of 280 adults with chronic heart failure was enrolled. Widely used, validated, and sensitive measures of sleep quality (Pittsburgh Sleep Quality Index), daytime sleepiness (Epworth Sleepiness Scale, Stanford Sleepiness Scale), and behavioral alertness (Psychomotor Vigilance Test [PVT]) were collected at baseline, 3 and 6 months...
April 2016: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/26538305/resting-metabolic-rate-varies-by-race-and-by-sleep-duration
#6
RANDOMIZED CONTROLLED TRIAL
Andrea M Spaeth, David F Dinges, Namni Goel
OBJECTIVE: Short sleep duration is a significant risk factor for weight gain, particularly in African Americans and men. Increased caloric intake underlies this relationship, but it remains unclear whether decreased energy expenditure is a contributory factor. The current study assessed the impact of sleep restriction and recovery sleep on energy expenditure in African American and Caucasian men and women. METHODS: Healthy adults participated in a controlled laboratory study...
December 2015: Obesity
https://www.readbyqxmd.com/read/26446681/phenotypic-vulnerability-of-energy-balance-responses-to-sleep-loss-in-healthy-adults
#7
Andrea M Spaeth, David F Dinges, Namni Goel
Short sleep duration is a risk factor for increased hunger and caloric intake, late-night eating, attenuated fat loss when dieting, and for weight gain and obesity. It is unknown whether altered energy-balance responses to sleep loss are stable (phenotypic) over time, and the extent to which individuals differ in vulnerability to such responses. Healthy adults experienced two laboratory exposures to sleep restriction separated by 60-2132 days. Caloric intake, meal timing and weight were objectively measured...
October 8, 2015: Scientific Reports
https://www.readbyqxmd.com/read/26419654/all-cause-mortality-effects-of-replacing-sedentary-time-with-physical-activity-and-sleeping-using-an-isotemporal-substitution-model-a-prospective-study-of-201-129-mid-aged-and-older-adults
#8
Emmanuel Stamatakis, Kris Rogers, Ding Ding, David Berrigan, Josephine Chau, Mark Hamer, Adrian Bauman
BACKGROUND: Sedentary behaviour, sleeping, and physical activity are thought to be independently associated with health outcomes but it is unclear whether these associations are due to the direct physiological effects of each behaviour or because, across a finite 24-hour day, engagement in one behavior requires displacement of another. The aim of this study was to examine the replacement effects of sedentary behaviour (total sitting, television/computer screen time combined), sleeping, standing, walking, and moderate-to-vigorous physical activity on all-cause mortality using isotemporal substitution modelling...
2015: International Journal of Behavioral Nutrition and Physical Activity
https://www.readbyqxmd.com/read/26235159/joint-consensus-statement-of-the-american-academy-of-sleep-medicine-and-sleep-research-society-on-the-recommended-amount-of-sleep-for-a-healthy-adult-methodology-and-discussion
#9
Nathaniel F Watson, M Safwan Badr, Gregory Belenky, Donald L Bliwise, Orfeu M Buxton, Daniel Buysse, David F Dinges, James Gangwisch, Michael A Grandner, Clete Kushida, Raman K Malhotra, Jennifer L Martin, Sanjay R Patel, Stuart F Quan, Esra Tasali
The American Academy of Sleep Medicine and Sleep Research Society recently released a Consensus Statement regarding the recommended amount of sleep to promote optimal health in adults. This paper describes the methodology, background literature, voting process, and voting results for the consensus statement. In addition, we address important assumptions and challenges encountered during the consensus process. Finally, we outline future directions that will advance our understanding of sleep need and place sleep duration in the broader context of sleep health...
August 2015: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/26194576/joint-consensus-statement-of-the-american-academy-of-sleep-medicine-and-sleep-research-society-on-the-recommended-amount-of-sleep-for-a-healthy-adult-methodology-and-discussion
#10
Nathaniel F Watson, M Safwan Badr, Gregory Belenky, Donald L Bliwise, Orfeu M Buxton, Daniel Buysse, David F Dinges, James Gangwisch, Michael A Grandner, Clete Kushida, Raman K Malhotra, Jennifer L Martin, Sanjay R Patel, Stuart F Quan, Esra Tasali
The American Academy of Sleep Medicine and Sleep Research Society recently released a Consensus Statement regarding the recommended amount of sleep to promote optimal health in adults. This paper describes the methodology, background literature, voting process, and voting results for the consensus statement. In addition, we address important assumptions and challenges encountered during the consensus process. Finally, we outline future directions that will advance our understanding of sleep need and place sleep duration in the broader context of sleep health...
August 2015: Sleep
https://www.readbyqxmd.com/read/26194570/early-blood-lead-levels-and-sleep-disturbance-in-preadolescence
#11
Jianghong Liu, Xianchen Liu, Victoria Pak, Yingjie Wang, Chonghuai Yan, Jennifer Pinto-Martin, David Dinges
STUDY OBJECTIVES: Little is known about the effect of lead exposure on children's sleep. This study examined the association between blood lead levels (BLL) and sleep problems in a longitudinal study of children. SETTING: Four community-based elementary schools in Jintan City, China. PARTICIPANTS: 1,419 Chinese children. MEASUREMENT AND RESULTS: BLL were measured when children were aged 3-5 y, and sleep was assessed at ages 9-13 y...
December 2015: Sleep
https://www.readbyqxmd.com/read/26118830/a-new-likelihood-ratio-metric-for-the-psychomotor-vigilance-test-and-its-sensitivity-to-sleep-loss
#12
Mathias Basner, Sarah Mcguire, Namni Goel, Hengyi Rao, David F Dinges
The Psychomotor Vigilance Test (PVT) is a widely used assay of behavioural alertness sensitive to the effects of sleep loss and circadian misalignment. However, there is currently no accepted PVT composite outcome metric that captures response slowing, attentional lapses and compensatory premature reactions observed typically in sleep-deprived subjects. We developed a novel likelihood ratio metric (LRM) based on relative frequency distributions in 50 categories of reaction times (RT) and false starts in alert and sleep-deprived subjects (acute total sleep deprivation: n = 31 subjects)...
December 2015: Journal of Sleep Research
https://www.readbyqxmd.com/read/26039963/recommended-amount-of-sleep-for-a-healthy-adult-a-joint-consensus-statement-of-the-american-academy-of-sleep-medicine-and-sleep-research-society
#13
Nathaniel F Watson, M Safwan Badr, Gregory Belenky, Donald L Bliwise, Orfeu M Buxton, Daniel Buysse, David F Dinges, James Gangwisch, Michael A Grandner, Clete Kushida, Raman K Malhotra, Jennifer L Martin, Sanjay R Patel, Stuart F Quan, Esra Tasali
Sleep is essential for optimal health. The American Academy of Sleep Medicine (AASM) and Sleep Research Society (SRS) developed a consensus recommendation for the amount of sleep needed to promote optimal health in adults, using a modified RAND Appropriateness Method process. The recommendation is summarized here. A manuscript detailing the conference proceedings and evidence supporting the final recommendation statement will be published in SLEEP and the Journal of Clinical Sleep Medicine.
2015: Sleep
https://www.readbyqxmd.com/read/25979105/recommended-amount-of-sleep-for-a-healthy-adult-a-joint-consensus-statement-of-the-american-academy-of-sleep-medicine-and-sleep-research-society
#14
Nathaniel F Watson, M Safwan Badr, Gregory Belenky, Donald L Bliwise, Orfeu M Buxton, Daniel Buysse, David F Dinges, James Gangwisch, Michael A Grandner, Clete Kushida, Raman K Malhotra, Jennifer L Martin, Sanjay R Patel, Stuart F Quan, Esra Tasali, Michael Twery, Janet B Croft, Elise Maher, Jerome A Barrett, Sherene M Thomas, Jonathan L Heald
Sleep is essential for optimal health. The American Academy of Sleep Medicine (AASM) and Sleep Research Society (SRS) developed a consensus recommendation for the amount of sleep needed to promote optimal health in adults, using a modified RAND Appropriateness Method process. The recommendation is summarized here. A manuscript detailing the conference proceedings and evidence supporting the final recommendation statement will be published in SLEEP and the Journal of Clinical Sleep Medicine.
June 2015: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/25707282/phenotyping-of-neurobehavioral-vulnerability-to-circadian-phase-during-sleep-loss
#15
REVIEW
Namni Goel, Mathias Basner, David F Dinges
The two-process model of sleep-wake regulation posits a neurobiological drive for sleep that varies homeostatically (increasing as a saturating exponential during wakefulness and decreasing in a like manner during sleep) and a circadian process that neurobiologically modulates both the homeostatic drive for sleep and waking alertness and performance. Endogenous circadian rhythms in neurobehavioral functions, including physiological alertness and cognitive performance, have been demonstrated using laboratory protocols that reveal the interaction of the biological clock with the sleep homeostatic drive...
2015: Methods in Enzymology
https://www.readbyqxmd.com/read/25675494/oxalic-acid-and-diacylglycerol-36-3-are-cross-species-markers-of-sleep-debt
#16
Aalim M Weljie, Peter Meerlo, Namni Goel, Arjun Sengupta, Matthew S Kayser, Ted Abel, Morris J Birnbaum, David F Dinges, Amita Sehgal
Sleep is an essential biological process that is thought to have a critical role in metabolic regulation. In humans, reduced sleep duration has been associated with risk for metabolic disorders, including weight gain, diabetes, obesity, and cardiovascular disease. However, our understanding of the molecular mechanisms underlying effects of sleep loss is only in its nascent stages. In this study we used rat and human models to simulate modern-day conditions of restricted sleep and addressed cross-species consequences via comprehensive metabolite profiling...
February 24, 2015: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/25645575/altered-salience-network-connectivity-predicts-macronutrient-intake-after-sleep-deprivation
#17
Zhuo Fang, Andrea M Spaeth, Ning Ma, Senhua Zhu, Siyuan Hu, Namni Goel, John A Detre, David F Dinges, Hengyi Rao
Although insufficient sleep is a well-recognized risk factor for overeating and weight gain, the neural mechanisms underlying increased caloric (particularly fat) intake after sleep deprivation remain unclear. Here we used resting-state functional magnetic resonance imaging and examined brain connectivity changes associated with macronutrient intake after one night of total sleep deprivation (TSD). Compared to the day following baseline sleep, healthy adults consumed a greater percentage of calories from fat and a lower percentage of calories from carbohydrates during the day following TSD...
February 3, 2015: Scientific Reports
https://www.readbyqxmd.com/read/25409102/how-acute-total-sleep-loss-affects-the-attending-brain-a-meta-analysis-of-neuroimaging-studies
#18
Ning Ma, David F Dinges, Mathias Basner, Hengyi Rao
STUDY OBJECTIVES: Attention is a cognitive domain that can be severely affected by sleep deprivation. Previous neuroimaging studies have used different attention paradigms and reported both increased and reduced brain activation after sleep deprivation. However, due to large variability in sleep deprivation protocols, task paradigms, experimental designs, characteristics of subject populations, and imaging techniques, there is no consensus regarding the effects of sleep loss on the attending brain...
2015: Sleep
https://www.readbyqxmd.com/read/25364070/cognitive-workload-and-sleep-restriction-interact-to-influence-sleep-homeostatic-responses
#19
RANDOMIZED CONTROLLED TRIAL
Namni Goel, Takashi Abe, Marcia E Braun, David F Dinges
STUDY OBJECTIVES: Determine the effects of high versus moderate workload on sleep physiology and neurobehavioral measures, during sleep restriction (SR) and no sleep restriction (NSR) conditions. DESIGN: Ten-night experiment involving cognitive workload and SR manipulations. SETTING: Controlled laboratory environment. PARTICIPANTS: Sixty-three healthy adults (mean ± standard deviation: 33.2 ± 8.7 y; 29 females), age 22-50 y...
November 2014: Sleep
https://www.readbyqxmd.com/read/25325472/sociodemographic-characteristics-and-waking-activities-and-their-role-in-the-timing-and-duration-of-sleep
#20
Mathias Basner, Andrea M Spaeth, David F Dinges
STUDY OBJECTIVES: Chronic sleep restriction is prevalent in the U.S. population and associated with increased morbidity and mortality. The primary reasons for reduced sleep are unknown. Using population data on time use, we sought to identify individual characteristics and behaviors associated with short sleep that could be targeted for intervention programs. DESIGN: Analysis of the American Time Use Survey (ATUS). SETTING: Cross-sectional annual survey conducted by the U...
December 2014: Sleep
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