Fynn Schmitz, Rafael Klimas, Marie Spenner, Aurelian Schumacher, Alina Hieke, Tineke Greiner, Elena Enax-Krumova, Melissa Sgodzai, Miriam Fels, Jil Brünger, Sophie Huckemann, Philipp Stude, Martin Tegenthoff, Ralf Gold, Jörg Philipps, Anna Lena Fisse, Thomas Grüter, Kalliopi Pitarokoili, Jeremias Motte, Dietrich Sturm
PURPOSE: Corneal confocal microscopy is a noninvasive imaging technique to analyze corneal nerve fibers and corneal inflammatory cells (CICs). The amount of CICs is a potential biomarker of disease activity in chronic autoinflammatory diseases. To date, there are no standardized criteria for the morphological characterization of CICs. The aim was to establish a protocol for a standardized morphological classification of CICs based on a literature search and to test this protocol for applicability and reliability...
April 4, 2024: Cornea