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https://www.readbyqxmd.com/read/28453434/follicular-morphological-characteristics-may-be-associated-with-invasion-in-follicular-thyroid-neoplasms-with-papillary-like-nuclear-features
#1
Nuray Can, Mehmet Celik, Yavuz Atakan Sezer, Filiz Ozyilmaz, Semra Ayturk, Ebru Tastekin, Necdet Sut, Hakan Gurkan, Funda Ustun, Buket Yilmaz Bulbul, Sibel Guldiken, Fulya Oz Puyan
The newly proposed nomenclature and diagnostic criteria for encapsulated follicular variant of papillary thyroid carcinoma (EFVPTC), the noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP), could improve the consistency and accuracy of diagnosing this entity. Diagnosis of NIFTP requires evaluation of the complete tumor border or capsule. The presence of tumor invasion in follicular thyroid neoplasms with papillary-like nuclear features has been recently discussed by many authors...
April 28, 2017: Bosnian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/28446997/endoscopic-submucosal-dissection-and-endoscopic-mucosal-resection-for-early-stage-esophageal-cancer
#2
REVIEW
Bo Ning, Mohamed M Abdelfatah, Mohamed O Othman
Mortality from esophageal cancer remains high despite advances in medical therapy. Although the incidence of squamous cell carcinoma of the esophagus remains unchanged, the incidence of the esophageal adenocarcinoma has increased over time. Gastroesophageal reflux disease (GERD and obesity are contributing factors to the development of Barrett's esophagus and subsequent development of adenocarcinoma. Early recognition of the disease can lead to resection of esophageal cancer prior to the development of lymphovascular invasion...
March 2017: Annals of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/28445219/canadian-national-guidelines-and-recommendations-for-integrating-career-advising-into-medical-school-curricula
#3
Kelly Howse, June Harris, Nancy Dalgarno
Career planning, decision making about specialty choice, and preparation for residency matching are significant sources of stress for medical students. Attempts have been made to structure and formalize career advising by including it in accreditation standards. There is an expressed need for national guidelines on career advising for medical students. The Future of Medical Education in Canada Postgraduate (FMEC PG) Implementation Project was created to ensure Canadian medical trainees receive the best education possible...
April 25, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28444083/interictal-abnormal-fmri-activation-of-visual-areas-during-a-motor-task-cued-by-visual-stimuli-in-migraine
#4
Adriana Bastos Conforto, Khallil Taverna Chaim, Mario Fernando Prieto Peres, André Leite Gonçalves, Inara Laurindo Siqueira, Maria Angela Maramaldo Barreiros, Edson Amaro
Objective: To assess changes in blood-oxygen-level-dependent activity after light deprivation compared to regular light exposure in subjects with migraine in the interictal state and in controls. Methods: Ten subjects with migraine and ten controls participated in two sessions of functional magnetic resonance imaging. In each session, they performed a finger-tapping task with the right hand, cued by visual stimuli. They were scanned before and after 30 minutes of light deprivation or light exposure...
January 2017: Einstein
https://www.readbyqxmd.com/read/28442663/histochemical-assessment-for-osteoblastic-activity-coupled-with-dysfunctional-osteoclasts-in-c-src-deficient-mice
#5
Hisashi Toray, Tomoka Hasegawa, Naoko Sakagami, Erika Tsuchiya, Ai Kudo, Shen Zhao, Yasuhito Moritani, Miki Abe, Taiji Yoshida, Tomomaya Yamamoto, Tsuneyuki Yamamoto, Kimimitsu Oda, Nobuyuki Udagawa, Paulo Henrique Luiz de Freitas, Minqi Li
Since osteoblastic activities are believed to be coupled with osteoclasts, we have attempted to histologically verify which of the distinct cellular circumstances, the presence of osteoclasts themselves or bone resorption by osteoclasts, is essential for coupled osteoblastic activity, by examining c-fos(-/-) or c-src(-/-) mice. Osteopetrotic c-fos deficient (c-fos(-/-)) mice have no osteoclasts, while c-src deficient (c-src(-/-)) mice, another osteopetrotic model, develop dysfunctional osteoclasts due to a lack of ruffled borders...
2017: Biomedical Research
https://www.readbyqxmd.com/read/28440952/thyroid-cancer-incidence-among-asian-immigrants-to-ontario-canada-a-population-based-cohort-study
#6
Baiju R Shah, Rebecca Griffiths, Stephen F Hall
BACKGROUND: The highest rates of thyroid cancer are observed in Pacific Island nations as well as Australia and Asian countries bordering the Pacific. The objective of this study was to determine the risk for thyroid cancer among immigrants to Canada from Southeast and East Asia compared with immigrants from other regions and nonimmigrants. METHODS: This was a population-based, longitudinal cohort study using health care administrative data to examine all residents of Ontario without pre-existing thyroid cancer...
April 25, 2017: Cancer
https://www.readbyqxmd.com/read/28439544/quantifying-the-negative-impact-of-brain-drain-on-the-integration-of-european-science
#7
Omar A Doria Arrieta, Fabio Pammolli, Alexander M Petersen
The 2004/2007 European Union (EU) enlargement by 12 member states offers a unique opportunity to quantify the impact of EU efforts to expand and integrate the scientific competitiveness of the European Research Area (ERA). We apply two causal estimation schemes to cross-border collaboration data extracted from millions of academic publications from 1996 to 2012, which are disaggregated across 14 subject areas and 32 European countries. Our results illustrate the unintended consequences following the 2004/2007 enlargement, namely, its negative impact on cross-border collaboration in science...
April 2017: Science Advances
https://www.readbyqxmd.com/read/28430974/using-transcranial-magnetic-stimulation-of-the-undamaged-brain-to-identify-lesion-sites-that-predict-language-outcome-after-stroke
#8
Diego L Lorca-Puls, Andrea Gajardo-Vidal, Mohamed L Seghier, Alexander P Leff, Varun Sethi, Susan Prejawa, Thomas M H Hope, Joseph T Devlin, Cathy J Price
Transcranial magnetic stimulation focused on either the left anterior supramarginal gyrus or opercular part of the left inferior frontal gyrus has been reported to transiently impair the ability to perform phonological more than semantic tasks. Here we tested whether phonological processing abilities were also impaired following lesions to these regions in right-handed, English speaking adults, who were investigated at least 1 year after a left-hemisphere stroke. When our regions of interest were limited to 0...
April 18, 2017: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/28428666/linear-short-term-heart-rate-variability-parameters-of-subjects-tobacco-cigarette-smokers-and-subjects-nonsmokers-in-preoperative-period
#9
Meldijana Omerbegovic
BACKGROUND: Variations of heart cycles reflect complex dynamic cardiocirculatory regulatory systems in humans. Exposure to tobacco from cigarettes has been shown to elicit specific alterations of heart rate variability parameters leading to predominance of sympathetic and decreasing parameters of parasympathetic measures of cardiac autonomic nervous system tone. AIM: The aim of the trial was assessing differences of linear parameters of heart rate variability in subjects with habit of consuming of cigarettes tobacco in regard to subjects who are not consumers of tobacco...
February 2017: Medical Archives
https://www.readbyqxmd.com/read/28424805/cruising-through-the-journey-without-getting-drowned-the-saga-of-a-phd-student-in-the-netherlands
#10
Louise van Galen, Joyce Wachelder
Young medical trainees all over the world are encouraged to investigate unknown areas of medicine that need clarification. This often leads them to undertake a PhD (Doctor of Philosophy). Being curious, critical, and creative are necessary competences which enable us to engender scientific research within acute (internal) medicine. Worldwide, huge numbers of professionals are pursuing a PhD, with the aim of receiving a 'Doctor'-title. These PhD trajectories vary distinctly between countries. Since the distances in the scientific world are getting smaller and it is becoming more easy to work with each other across borders, it might be interesting to know what it requires to become an academic 'doctor' overseas...
2017: Acute Medicine
https://www.readbyqxmd.com/read/28422401/mlc-based-penumbra-softener-of-edw-borders-to-reduce-junction-inhomogeneities
#11
Stanislaw Szpala, Kirpal Kohli
Junctions of fields are known to be susceptible to developing cold or hot spots in the presence of even small geometrical misalignments. Reduction of these dose inhomogeneities can be accomplished through decreasing the dose gradients in the penumbra, but currently it cannot be done for enhanced dynamic wedges (EDW). An MLC-based penumbra softener was developed in the developer mode of TrueBeam linacs to reduce dose gradients across the side border of EDWs. The movement of each leaf was individually synchronized with the movement of the dynamic Y jaw to soften the penumbra in the same manner along the entire field border, in spite of the presence of the dose gradient of the EDW...
April 19, 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28420590/volume-and-dimensions-of-angiographically-normal-coronary-arteries-assessed-by-multidetector-computed-tomography
#12
Samuel Kiil Sørensen, Jørgen Tobias Kühl, Andreas Fuchs, Jakob Boesgaard Norsk, Lars Valeur Køber, Børge Grønne Nordestgaard, Klaus Fuglsang Kofoed
BACKGROUND: The objective of this study was to determine normal values for coronary artery volume (CAV) and individual vasculature and segment dimensions. METHODS: We examined 200 healthy volunteers with an Agatston score of 0 and a normal, high quality coronary CTA. Using 320 slice multidetector row CT and designated vessel tracing software with border detection algorithm, the main coronary arteries and branches were delineated and total and segmental dimensions calculated...
April 4, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28419499/periodontitis-changes-renal-structures-by-oxidative-stress-and-lipid-peroxidation
#13
Luiz Felipe de Carvalho França, Any Carolina Cardoso Guimarães Vasconcelos, Felipe Rodolfo Pereira da Silva, Even Herlany Pereira Alves, Joaquina Dos Santos Carvalho, David Di Lenardo, Luan Kelves Miranda de Souza, André Luiz Dos Reis Barbosa, Jand-Venes Rolim Medeiros, Jefferson Soares de Oliveira, Daniel Fernando Pereira Vasconcelos
OBJECTIVE: The aim of this study was to investigate whether experimental periodontitis cause changes to the renal tissues and imbalance in oxidative stress in kidneys. METHODS: Twenty-two female Wistar rats were separated into two groups: control and periodontitis. We assessed the following parameters: gingival bleeding index (GBI), tooth mobility, gum malondialdehyde (MDA), myeloperoxidase (MPO) activity, probing pocket depth (PPD), alveolar bone loss (ABL) for periodontal tissues; histomorphometric measures associated with renal corpuscle and histopathological aspects (evaluation of brush border) for kidneys; as also blood and urine biomarkers...
April 17, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28413452/ankle-and-toe-muscle-strength-characteristics-in-runners-with-a-history-of-medial-tibial-stress-syndrome
#14
Junya Saeki, Masatoshi Nakamura, Sayaka Nakao, Kosuke Fujita, Ko Yanase, Katsuyuki Morishita, Noriaki Ichihashi
BACKGROUND: A high proportion of flexor digitorum longus attachment is found at the posteromedial border of the tibia, which is the most common location of medial tibial stress syndrome (MTSS). Therefore, plantar flexion strength of the lesser toes could be related to MTSS; however, the relationship between MTSS and muscle strength of the hallux and lesser toes is not yet evaluated due to the lack of quantitative methods. This study investigated the muscle strength characteristics in runners with a history of MTSS by using a newly developed device to measure the muscle strength of the hallux, lesser toes, and ankle...
2017: Journal of Foot and Ankle Research
https://www.readbyqxmd.com/read/28409355/percutaneous-mr-guided-focal-cryoablation-for-recurrent-prostate-cancer-following-radiation-therapy-retrospective-analysis-of-iceball-margins-and-outcomes
#15
Christiaan G Overduin, Sjoerd F M Jenniskens, J P Michiel Sedelaar, Joyce G R Bomers, Jurgen J Fütterer
OBJECTIVES: To evaluate iceball margins after magnetic resonance (MR)-guided focal salvage prostate cryoablation and determine the correlation with local outcome. METHODS: A retrospective review was performed on 47 patients that underwent percutaneous MR-guided focal cryoablation for biopsy-proven locally recurrent prostate cancer after primary radiotherapy. Preprocedural diagnostic and intraprocedural MR images were analysed to derive three-directional iceball margins...
April 13, 2017: European Radiology
https://www.readbyqxmd.com/read/28407354/defining-mandibular-morphology-in-robin-sequence-a-matched-case-control-study
#16
Srinivas M Susarla, Nefeli Vasilakou, Hitesh Kapadia, Mark Egbert, Richard A Hopper, Kelly N Evans
Robin Sequence (RS) is classically defined as the triad of micrognathia, glossoptosis, and airway obstruction. While there remains significant debate over diagnostic criteria for severity, there is consensus regarding micrognathia as a defining feature of the condition. The purpose of this study was to compare mandibular morphology among infants and children with RS to infants and children without RS using maxillofacial computed tomography. Our hypothesis was that there are discrete morphologic differences between RS and non-RS mandibles...
April 13, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28405147/endosonographic-surveillance-of-1-3-cm-gastric-submucosal-tumors-originating-from-muscularis-propria
#17
Ming-Luen Hu, Keng-Liang Wu, Chi-Sin Changchien, Seng-Kee Chuah, Yi-Chun Chiu
AIM: To observe the natural course of 1-3 cm gastric submucosal tumors originating from the muscularis propria (SMTMPs). METHODS: By reviewing the computerized medical records over a period of 14 years (2000-2013), patients with 1-3 cm gastric SMTMPs who underwent at least two endoscopic ultrasound (EUS) examinations were enrolled. Tumor progression was defined as a ≥ 1.2 times enlargement in tumor diameter observed during EUS surveillance. All patients were divided into stationary and progressive subgroups and further analyzed...
March 28, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28403645/classification-the-key-to-understanding-facial-pain
#18
Peter Svensson, Arne May
It is indisputable that the global scientific advances in headache research, be it bench or bedside, have benefited enormously from the operational diagnostic criteria published in 1988. Today, this classification system is indispensable. The reason for this success is a low inter-rater variability. In general, orofacial pain conditions are less well characterised - with the noticeable exemption of temporomandibular disorder pain. Tremendous work has been put into changing this, and significant progress has been achieved - in particular, in terms of the clinical implications and overriding conceptual models for oro-facial pain...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/28387845/identification-of-risk-factors-for-primary-mers-cov-infection-in-camel-workers-in-qatar-2013-2014-a-case-control-study
#19
Reina S Sikkema, Elmoubasher A B A Farag, Sayed Himatt, Adel K Ibrahim, Hamad Al-Romaihi, Salih A Al-Marri, Mohamed Al-Thani, Ahmed M H El-Sayed, Mohammed Al-Hajri, Bart L Haagmans, Marion P G Koopmans, Chantal B E M Reusken
The transmission routes and risk factors for zoonotic MERS-CoV infections are still unknown. We used the WHO questionnaire for MERS-CoV case-control studies to assess risk factors for human MERS-CoV seropositivity at a farm complex in Qatar. Nine camel workers with MERS-CoV antibodies and 43 workers without antibodies were included. Some camel-related activities may pose a higher risk of MERS-CoV infection, as well as cross-border movements of camels, poor hand hygiene and overnight hospital stays with respiratory complaints ...
April 6, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28384119/status-of-water-pollution-in-relation-to-industrialization-in-rajasthan
#20
Ritu Singh Rajput, Sonali Pandey, Seema Bhadauria
India is a large and densely populated country; its economy is largely agricultural. Making the best use of the country's manpower has always posed a challenge. Industrialization could become a dominant component of the economy and displace agriculture. Traditional livelihoods of occupational groups are threatened by the practice of disposing untreated industrial waste into rivers and bodies of water. These uncontrolled disposals impact local natural resources with negative long-term effects. Industrialization is the development of intellectual and financial trade that changes a predominantly rustic culture into a modern one...
April 6, 2017: Reviews on Environmental Health
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