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physical activity and cancer

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https://www.readbyqxmd.com/read/28640766/impact-of-recurrence-of-ovarian-cancer-on-quality-of-life-and-outlook-for-the-future
#1
Nicoletta Colombo, Domenica Lorusso, Paolo Scollo
OBJECTIVE: Ovarian cancer recurs in most patients, with a 5-year survival rate less than 30%. Quality of life is an increasingly important issue in patients with cancer, but there are limited data in women with recurrent ovarian cancer in this regard. MATERIALS AND METHODS: We used an ad hoc questionnaire to compare changes in health perceptions, burden of disease, and expectations for the future quality of life in women with and without recurrence of ovarian cancer...
July 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28637134/an-exploratory-qualitative-study-of-the-meaning-and-value-of-a-running-walking-program-for-women-after-a-diagnosis-of-breast-cancer
#2
Jennifer Brunet, Stephanie Saunders, Wendy Gifford, Roanne Thomas, Ryan Hamilton
PURPOSE: To generate insights into the personal meaning and value of a running/walking program for women after a diagnosis of breast cancer. METHODS: After completing a 12-week running/walking program with a 5-km training goal, eight women were interviewed and seven participated in a focus group. The interviews and focus group were audio-recorded and transcribed verbatim. Data were thematically analyzed. RESULTS: Data portrayed the personal benefits and value of the clinic...
February 10, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28637074/-nutrition-in-cancer-effective-in-prevention-and-treatment
#3
Jann Arends
Nutritional effects on cancer occurrence and on treatment outcome in cancer patients may depend on food preferences and on the quantity of foods supplied. However, it has been difficult to reliably show beneficial effects of specific dietary concepts on cancer incidence. On the other hand, obesity as a result of chronic overfeeding has been linked firmly to an increased risk of a number of cancers as well as on cancer recurrence after treatment. Metabolic consequences of obesity and other components of the metabolic syndrome may be responsible for inducing and/or promoting cancer growth and should be antagonized by regular moderate physical activity in healthy subjects and in cancer survivors...
June 2017: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/28636526/does-health-coaching-grow-capacity-in-cancer-survivors-a-systematic-review
#4
Suzette Barakat, Kasey Boehmer, Marwan Abdelrahim, Sangwoo Ahn, Abdulrahman A Al-Khateeb, Neri Álvarez Villalobos, Larry Prokop, Patricia J Erwin, Kirsten Fleming, Valentina Serrano, Gabriela Spencer-Bonilla, Mohammad Hassan Murad
Interventions that grow patient capacity to do the work of health care and life are needed to support the health of cancer survivors. Health coaching may grow capacity. This systematic review of health coaching interventions explored coaching's ability to grow capacity of cancer survivors. The authors included randomized trials or quasi-experimental studies comparing coaching to alternative interventions, and adhered to PRISMA reporting guidelines. Data were analyzed using the Theory of Patient Capacity (BREWS: Capacity is affected by factors that influence ability to reframe Biography ["B"], mobilize or recruit Resources ["R"], interact with the Environment of care ["E"], accomplish Work ["W"]), and function Socially ["S"])...
June 21, 2017: Population Health Management
https://www.readbyqxmd.com/read/28635971/exercise-among-women-with-ovarian-cancer-a-feasibility-and-pre-post-test-exploratory-pilot-study
#5
Xiaochen Zhang, Daniel McClean, Emily Ko, Mark A Morgan, Kathryn Schmitz
PURPOSE/OBJECTIVES: To establish the feasibility and acceptability of completing a higher dose of the planned physical activity volume among women with ovarian cancer, including those undergoing active treatment. 
. DESIGN: A pre-/post-test exercise intervention. All participants were asked to complete 225 minutes per week of physical activity for 26 weeks. Multiple supports were provided, including exercise DVDs, self-reported logs, and an objective physical activity tracker (Fitbit®)...
May 1, 2017: Oncology Nursing Forum
https://www.readbyqxmd.com/read/28634868/occurrence-removal-and-health-risk-assessment-of-phthalate-esters-in-the-process-streams-of-two-different-wastewater-treatment-plants-in-lagos-and-ogun-states-nigeria
#6
O O Olujimi, O A Aroyeun, T F Akinhanmi, T A Arowolo
Phthalate esters (PEs) are one of the environmentally active organic pollutants capable of causing endocrine disruption. The levels of PE congeners were determined in the influent and effluent from Covenant Oxidation Pond (COP) and Ikeja Wastewater Treatment Plant (IWWTP). Standard methods were adopted for determining the physical and chemical parameters of the water samples. The water samples for PE congener's determination were collected, acidified and stored at 4 °C prior to liquid-liquid extraction and analysis by gas chromatograph...
July 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28634625/serum-antioxidant-capacity-biochemical-profile-and-body-composition-of-breast-cancer-survivors-in-a-randomized-mediterranean-dietary-intervention-study
#7
Maria Skouroliakou, D Grosomanidis, P Massara, C Kostara, P Papandreou, D Ntountaniotis, G Xepapadakis
PURPOSE: Increasing evidence suggests that Mediterranean Diet (MD) is correlated with reduced risk of breast cancer (BC) and cancer mortality, since it modifies patients' serum antioxidant capacity, body composition and biochemical parameters. The aim of the study was to investigate whether a dietary intervention based on MD has a beneficial effect on these factors. METHODS: In this intervention study, seventy female BC survivors were randomly assigned to (1) the intervention group (personalized dietary intervention based on MD) and (2) the control group (received the updated American Cancer Society Guidelines on Nutrition and Physical Activity for Cancer Prevention and ad libitum diet)...
June 20, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28632252/improving-oncology-nurses-knowledge-about-nutrition-and-physical-activity-for-cancer-survivors
#8
Merel R van Veen, Meeke Hoedjes, Joline J Versteegen, Nienke van de Meulengraaf-Wilhelm, Ellen Kampman, Sandra Beijer
PURPOSE/OBJECTIVES: To assess what percentage of oncology nurses perceived themselves as having insufficient knowledge to provide advice on nutrition and/or physical activity (PA), which characteristics were associated with nurses' perception, and whether the content and information sources differed among those nurses.
. DESIGN: A cross-sectional study.
. SETTING: A web-based survey among oncology nurses in the Netherlands.
. SAMPLE: 355 oncology nurses provided advice on nutrition; of these, 327 provided advice on PA...
July 1, 2017: Oncology Nursing Forum
https://www.readbyqxmd.com/read/28632248/perceived-benefits-and-barriers-to-exercise-for-recently-treated-adults-with-acute-leukemia
#9
Ashley Leak Bryant, AnnMarie L Walton, Mackenzi Pergolotti, Brett Phillips, Charlotte Bailey, Deborah K Mayer, Claudio Battaglini
PURPOSE/OBJECTIVES: To explore perceived exercise benefits and barriers in adults with acute leukemia who recently completed an inpatient exercise intervention during induction therapy.
. RESEARCH APPROACH: Descriptive, exploratory design using semistructured interviews.
. SETTING: Inpatient hematology/oncology unit at North Carolina Cancer Hospital in Chapel Hill.
. PARTICIPANTS: 6 adults with acute leukemia aged 35-67 years...
July 1, 2017: Oncology Nursing Forum
https://www.readbyqxmd.com/read/28632242/exploring-gender-differences-in-self-reported-physical-activity-and-health-among-older-caregivers
#10
Colleen A Cuthbert, Kathryn King-Shier, Dianne Tapp, Dean Ruether, S Nicole Culos-Reed
PURPOSE/OBJECTIVES: To document self-reported physical health and activity levels of older caregivers. Gender differences in physical health, physical activity levels, and predictors of physical activity were also examined.
. DESIGN: A cross-sectional study.
. SETTING: Tom Baker Cancer Centre in Calgary, Alberta, Canada.
. SAMPLE: 130 caregivers aged 60 years or older caring for individuals with breast, prostate, or colorectal cancer...
July 1, 2017: Oncology Nursing Forum
https://www.readbyqxmd.com/read/28632240/body-related-shame-and-guilt-predict-physical-activity-in-breast-cancer-survivors-over-time
#11
Andrée L Castonguay, Carsten Wrosch, Eva Pila, Catherine M Sabiston
PURPOSE/OBJECTIVES: To test body-related shame and guilt as predictors of breast cancer survivors' (BCS') moderate to vigorous intensity physical activity (MVPA) during six months and to examine motivational regulations as mediators of this association.
. DESIGN: Prospective study.
. SETTING: Survivors were recruited through advertisements and oncologist referrals from medical clinics and hospitals in Montreal, Quebec, Canada.
. SAMPLE: 149 female BCS...
July 1, 2017: Oncology Nursing Forum
https://www.readbyqxmd.com/read/28629338/a-phase-2-randomized-trial-to-evaluate-the-impact-of-a-supervised-exercise-program-on-cardiotoxicity-at-3%C3%A2-months-in-patients-with-her2-overexpressing-breast-cancer-undergoing-adjuvant-treatment-by-trastuzumab-design-of-the-cardapac-study
#12
Quentin Jacquinot, Nathalie Meneveau, Marion Chatot, Franck Bonnetain, Bruno Degano, Malika Bouhaddi, Gilles Dumoulin, Dewi Vernerey, Xavier Pivot, Fabienne Mougin
BACKGROUND: The overexpression of human epidermal growth factor receptor-2 (HER2) in breast cancer is a poor prognosis. Trastuzumab improves overall survival but is associated with cardiotoxicity, especially a decline in left ventricular ejection fraction (LVEF). In addition, chemotherapy and radiotherapy increase fatigue and pain, decrease physical capacity and health-related quality of life. To date, no study has evaluated the benefits of physical activity on the side effects of treatment in patients with HER2 positive breast cancer...
June 19, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28629307/tumor-reversion-mesenchymal-epithelial-transition-as-a-critical-step-in-managing-the-tumor-microenvironment-cross-talk
#13
Mariano Bizzarri, Alessandra Cucina, Sara Proietti
Tumour reversion represents a promising field of investigation. The occurrence of cancer reversion both in vitro and in vivo has been ascertained by an increasing number of reports. The reverting process may be triggered in a wide range of different cancer types by both molecular and physical cues. This process encompasses mandatorily a change in the cell-stroma interactions, leading to profound modification in tissue architecture. Indeed, cancer reversion may be obtained by only resetting the overall burden of biophysical cues acting on the cell-stroma system, thus indicating that conformational changes induced by cell shape and cytoskeleton remodelling trigger downstream the cascade of molecular events required for phenotypic reversion...
June 8, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28628306/lysine-deacetylation-by-hdac6-regulates-the-kinase-activity-of-akt-in-human-neural-progenitor-cells
#14
Jonathan Iaconelli, Jasmin Lalonde, Bradley Watmuff, Bangyan Liu, Ralph Mazitschek, Stephen J Haggarty, Rakesh Karmacharya
AKT family of serine-threonine kinases functions downstream of phosphatidylinositol 3-kinase (PI3K) to transmit signals by direct phosphorylation of a number of targets, including the mammalian target of rapamycin (mTOR), glycogen synthase kinase 3β (GSK3β) and β-catenin. AKT binds to phosphatidylinositol (3,4,5)-triphosphate (PIP3) generated by PI3K activation, which results in its membrane localization and subsequent activation through phosphorylation by phosphoinositide-dependent protein kinase 1 (PDK1)...
June 19, 2017: ACS Chemical Biology
https://www.readbyqxmd.com/read/28627254/randomized-trial-of-a-lifestyle-physical-activity-intervention-for-breast-cancer-survivors-effects-on-transtheoretical-model-variables
#15
Stacie Scruggs, Scherezade K Mama, Cindy L Carmack, Tommy Douglas, Pamela Diamond, Karen Basen-Engquist
This study examined whether a physical activity intervention affects transtheoretical model (TTM) variables that facilitate exercise adoption in breast cancer survivors. Sixty sedentary breast cancer survivors were randomized to a 6-month lifestyle physical activity intervention or standard care. TTM variables that have been shown to facilitate exercise adoption and progress through the stages of change, including self-efficacy, decisional balance, and processes of change, were measured at baseline, 3 months, and 6 months...
June 1, 2017: Health Promotion Practice
https://www.readbyqxmd.com/read/28627013/regular-exercise-improves-the-well-being-of-parents-of-children-with-cancer
#16
Gail C Halliday, Gordon C P Miles, Julie A Marsh, Rishi S Kotecha, Angela J Alessandri
AIM: Parents of children with cancer describe impaired physical and social functioning, sleep disturbance and poor mental health. Exercise-related interventions impact positively on these quality of life domains, but have not been examined in this population. The aim of this longitudinal pilot study was to explore the feasibility of a 12-week pedometer-monitored walking intervention among parents of children with cancer, assessing adherence to a set activity target of 70,000 steps per week, and to explore the benefits of physical activity on mental and physical health...
June 19, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28626876/optical-molecular-imaging-guided-radiation-therapy-part-2-integrated-x-ray-and-fluorescence-molecular-tomography
#17
Junwei Shi, Thirupandiyur S Udayakumar, Zhiqun Wang, Nesrin Dogan, Alan Pollack, Yidong Yang
PURPOSE: Differentiating tumor from its surrounding soft tissues is challenging for x-ray computed tomography (CT). Fluorescence molecular tomography (FMT) can directly localize the internal tumors targeted with specific fluorescent probes. A FMT system was developed and integrated onto a CT guided irradiator to improve tumor localization for image guided radiation. METHODS: The FMT system was aligned orthogonal to the cone beam CT onboard our previously developed image guided small animal arc radiation treatment system (iSMAART)...
June 19, 2017: Medical Physics
https://www.readbyqxmd.com/read/28626867/kind-of-blue-a-systematic-review-and-meta-analysis-of-music-interventions-in-cancer-treatment
#18
REVIEW
Margrethe Langer Bro, Kira Vibe Jespersen, Julie Bolvig Hansen, Peter Vuust, Niels Abildgaard, Jeppe Gram, Christoffer Johansen
OBJECTIVES: Music may be a valuable and low-cost coping strategy for cancer patients. We conducted a systematic review and meta-analysis to identify the psychological and physical effects of music interventions in cancer treatment. METHODS: We included randomized, controlled trials with adult patients in active cancer treatment exposed to different music interventions versus control conditions. Qualitative studies and systematic reviews were excluded. We identified a total of 2624 records through two systematic searches (June 2015, September 2016) in PubMed, Scopus, EMBASE, Cinahl, Web of Science, Cochrane and PsycINFO and used Risk of Bias Assessment, GRADE and Checklist for Reporting Music-Based Interventions to evaluate the music applied and quality of the studies...
June 18, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/28626069/how-many-deaths-from-colorectal-cancer-can-be-prevented-by-2030-a-scenario-based-quantification-of-risk-factor-modification-screening-and-treatment-in-norway
#19
Katrine Damgaard Skyrud, Tor Age Myklebust, Freddie Bray, Morten Tandberg Eriksen, Thomas de Lange, Inger Kristin Larsen, Bjørn Møller
BACKGROUND: Colorectal cancer (CRC) mortality can be reduced through risk factor modification (adherence to lifestyle recommendations), screening, and improved treatment. This study estimated the potential of these three strategies to modify CRC mortality rates in Norway. METHODS: The potential reduction in CRC mortality due to risk factor modification was estimated using the software Prevent, assuming that 50% of the population in Norway-who do not adhere to the various recommendations concerning prevention of smoking, physical activity, body weight, and intake of alcohol, red/processed meat, and fiber-started to follow the recommendations...
June 16, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28625550/maternal-exposure-to-western-diet-affects-adult-body-composition-and-voluntary-wheel-running-in-a-genotype-specific-manner-in-mice
#20
Layla Hiramatsu, Jarren Kay, Zoe Thompson, Jennifer Singleton, Gerald Claghorn, Ralph Lacerda de Albuquerque, Brittany Ho, Brett Ho, Gabriela Sanchez, Theodore Garland
Some human diseases, including obesity, Type II diabetes, and numerous cancers, are thought to be influenced by environments experienced in early life, including in utero. Maternal diet during the perinatal period may be especially important for adult offspring energy balance, potentially affecting both body composition and physical activity. This effect may be mediated by the genetic background of individuals, including, for example, potential "protective" mechanisms for individuals with inherently high levels of physical activity or high basal metabolic rates...
June 15, 2017: Physiology & Behavior
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