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physical activity and cancer

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https://www.readbyqxmd.com/read/29161462/the-influence-of-coping-strategies-on-subsequent-well-being-in-older-patients-with-cancer-a-comparison-with-two-control-groups
#1
Abdelbari Baitar, Frank Buntinx, Tine De Burghgraeve, Laura Deckx, Dirk Schrijvers, Hans Wildiers, Marjan van den Akker
OBJECTIVE: To evaluate dispositional coping strategies as predictors for changes in well-being after one year in older patients with cancer (OCP) and two control groups. METHODS: OCP were compared with two control groups: middle-aged patients with cancer (MCP) (ageing effect) and older patients without cancer (ONC) (cancer effect). Patients were interviewed shortly after a cancer diagnosis and one year later. Dispositional coping was measured with the Short Utrecht Coping List...
November 21, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/29161402/fit-for-surgery-perspectives-on-preoperative-exercise-testing-and-training
#2
K Richardson, D Z H Levett, S Jack, M P W Grocott
There is a consistent relationship between physical activity, physical fitness, and health across almost all clinical contexts, including the perioperative setting. Physiological measurements obtained during physical exercise may be used to infer the risk of adverse outcome after major surgery. In particular, data obtained from perioperative cardiopulmonary exercise testing have an expanding role in perioperative care. Such information may be used to inform a variety of changes in clinical practice, including interventions that may reduce the risk of perioperative adverse events...
December 1, 2017: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29159738/prospective-assessment-of-first-year-quality-of-life-after-pelvic-exenteration-for-gynecologic-malignancy-a-french-multicentric-study
#3
A Martinez, T Filleron, P Rouanet, P Méeus, E Lambaudie, J M Classe, F Foucher, F Narducci, S Gouy, F Guyon, F Marchal, E Jouve, P E Colombo, A Mourregot, M Rivoire, N Chopin, G Houvenaeghel, I Jaffre, J Leveque, V Lavoue, E Leblanc, P Morice, E Stoeckle, J L Verheaghe, D Querleu, G Ferron
BACKGROUND: Pelvic exenteration remains one of the most mutilating procedures, with important postoperative morbidity, an altered body image, and long-term physical and psychosocial concerns. This study aimed to assess quality of life (QOL) during the first year after pelvic exenteration for gynecologic malignancy performed with curative intent. METHODS: A French multicentric prospective study was performed by including patients who underwent pelvic exenteration...
November 20, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29158832/clinical-translation-and-first-in-human-use-of-44-sc-sc-psma-617-for-pet-imaging-of-metastasized-castrate-resistant-prostate-cancer
#4
Elisabeth Eppard, Ana de la Fuente, Martina Benešová, Ambreen Khawar, Ralph A Bundschuh, Florian C Gärtner, Barbara Kreppel, Klaus Kopka, Markus Essler, Frank Rösch
BACKGROUND: Various trivalent radiometals are well suited for labeling of DOTA-conjugated variants of Glu-ureido-based prostate-specific membrane antigen (PSMA) inhibitors. The DOTA-conjugate PSMA-617 has proven high potential in PSMA radioligand therapy (PSMA-RLT) of prostate cancer as well as PET imaging when labeled with lutetium-177 and gallium-68 respectively. Considering the relatively short physical half-life of gallium-68 this positron emitter precludes prolonged acquisition periods, as required for pre-therapeutic dosimetry or intraoperative applications...
2017: Theranostics
https://www.readbyqxmd.com/read/29158157/non-alcoholic-fatty-liver-disease-associates-with-increased-overall-mortality-and-death-from-cancer-cardiovascular-disease-and-liver-disease-in-women-but-not-men
#5
You-Cheol Hwang, Hong-Yup Ahn, Sung-Woo Park, Cheol-Young Park
BACKGROUND & AIMS: It is not clear whether women vs men have increased mortality from non-alcoholic fatty liver disease (NAFLD). We investigated whether NAFLD is associated with increased overall and cause-specific deaths in a Korean population using a large health study database. METHODS: We collected data on 318,224 subjects in Korea (165,131 men and 153,093 women) 20-94 years old (mean age of 39.3 years), enrolled in the Kangbuk Samsung Health Study cohort. All subjects underwent a comprehensive annual or biennial health examination in Seoul or Suwon, South Korea, from 2002 through 2012...
November 17, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29156913/symptom-clusters-using-the-brief-pain-inventory-in-patients-with-breast-cancer
#6
Vithusha Ganesh, Leah Drost, Nicholas Chiu, Liying Zhang, Leonard Chiu, Ronald Chow, Nicholas Lao, Bo Angela Wan, Justin Lee, Edward Chow, Carlo DeAngelis
BACKGROUND: The purpose of this study was to assess symptom clusters in functional interference using the brief pain inventory (BPI) in patients with non-metastatic breast cancer (BC) during and after chemotherapy. METHODS: A principal component analysis with varimax rotation was conducted on data from 228 patients to identify two clusters at baseline and two intervals following treatment. RESULTS: Physical (general activity, normal work, walking ability) and psychosocial (mood, relationships, sleep, enjoyment of life) interference clusters were present at baseline...
October 18, 2017: Annals of Palliative Medicine
https://www.readbyqxmd.com/read/29156535/hdacis-class-i-cancer-stem-cell-and-phytochemicals-cancer-therapy-and-prevention-implications
#7
REVIEW
Sahar Bayat, Mahmoud Shekari Khaniani, Jalal Choupani, Mohammad Reza Alivand, Sima Mansoori Derakhshan
Epigenetics is independent of the sequence events that physically affect the condensing of chromatin and genes expression. The unique epigenetic memories of various cells trigger exclusive gene expression profiling. According to different studies, the aberrant epigenetic signatures and impaired gene expression profiles are master occurrences in cancer cells in which oncogene and tumor suppressor genes are affected. Owing to the facts that epigenetic modifications are performed earlier than expression and are reversible, the epigenetic reprogramming of cancer cells could be applied potentially for their prevention, control, and therapy...
November 16, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29155166/do-correlates-of-pain-related-stoicism-and-cautiousness-differ-in-younger-and-older-people-with-advanced-cancer
#8
Kenneth Mah, Kim T Tran, Lynn R Gauthier, Gary Rodin, Camilla Zimmermann, David Warr, S Lawrence Librach, Malcolm Moore, Frances A Shepherd, Lucia Gagliese
Age differences are not evident in pain-related stoicism and cautiousness in people with cancer pain. Little is known about the factors associated with these pain-related attitudes or age-related patterns in these associations. The present cross-sectional study investigated the biopsychosocial correlates of the attitudes in younger and older patients with advanced cancer. Pain-related stoicism (fortitude, concealment, superiority) and cautiousness (self-doubt, reluctance) were assessed using the Pain Attitudes Questionnaire-Revised (PAQ-R)...
November 16, 2017: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/29154605/psychological-symptoms-and-subsequent-healthy-lifestyle-after-a-colorectal-cancer-diagnosis
#9
Claudia Trudel-Fitzgerald, Shelley S Tworoger, Elizabeth M Poole, Xuehong Zhang, Edward L Giovannucci, Jeffrey A Meyerhardt, Laura D Kubzansky
OBJECTIVE: Although medical professionals recommend lifestyle changes following a colorectal cancer (CRC) diagnosis to improve outcomes, such changes are not consistently implemented. This study examines whether higher distress is associated with lower likelihood of engaging in favorable behaviors after CRC diagnosis. METHOD: Women from the Nurses' Health Study prospective cohort who completed anxiety (n = 145) and depression (n = 227) symptom scales within 4 years after receiving a CRC diagnosis were included...
November 20, 2017: Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association
https://www.readbyqxmd.com/read/29154112/pre-diagnostic-plasma-enterolactone-concentrations-and-breast-cancer-prognosis-among-postmenopausal-women-the-danish-diet-cancer-and-health-cohort
#10
Cecilie Kyrø, Louise Hansen, Kirsten Frederiksen, Natalja P Nørskov, Knud Erik Bach Knudsen, Anne Kirstine Eriksen, Marianne Holm, Anne Tjønneland, Anja Olsen
BACKGROUND & AIMS: High intakes of the phytoestrogen lignans and high blood concentrations of its main biomarker, enterolactone, has been associated with a better breast cancer prognosis. We investigated the association between pre-diagnostic plasma concentrations of enterolactone and breast cancer prognosis (i.e. recurrence, breast cancer-specific mortality and all-cause mortality). METHODS: Plasma and data was available from the Danish Diet, Cancer and Health cohort...
November 8, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29151175/demographic-clinical-lifestyle-related-and-social-cognitive-correlates-of-physical-activity-in-head-and-neck-cancer-survivors
#11
Laurien M Buffart, Remco de Bree, Martine Altena, Sophie van der Werff, Constance H C Drossaert, Caroline M Speksnijder, Michiel W van den Brekel, Harriët Jager-Wittenaar, Neil K Aaronson, Martijn M Stuiver
PURPOSE: The purpose of the study is to identify demographic, clinical, lifestyle-related, and social-cognitive correlates of physical activity (PA) intention and behavior in head and neck cancer (HNC) survivors using the theory of planned behavior (TPB). METHODS: Data from two cross-sectional studies on correlates of PA in HNC survivors were pooled. Both studies used self-reports to assess PA and social-cognitive correlates. Potential correlates were collected via self-report or medical records...
November 18, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29150143/life-after-endometrial-cancer-a-systematic-review-of-patient-reported-outcomes
#12
Robert Shisler, Jennifer A Sinnott, Vivian Wang, Courtney Hebert, Ritu Salani, Ashley S Felix
BACKGROUND: Women with endometrial cancer (EC) are the second largest population of female cancer survivors in the United States. However, the outcomes of EC survivors, from the patient perspective, are not well-understood. Therefore, we conducted a systematic review of patient-reported outcomes (PROs) following an EC diagnosis. METHODS: We searched MEDLINE, EMBASE, Scopus, CINAHL, and reference lists to identify published observational studies that examined PROs among women with EC...
November 14, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/29149133/computer-based-exercise-program-effects-of-a-12-week-intervention-on-mood-and-fatigue-in-pediatric-patients-with-cancer%C3%A2
#13
Anna-Maria Platschek, Laura Kehe, Vera Abeln, Frank Berthold, Thorsten Simon, Heiko Strüder
BACKGROUND: Increasing rates of survival present a new set of physical and psychological challenges for children dealing with side effects during cancer treatment. Physical activity has been shown to be an effective strategy to reduce several side effects.
. OBJECTIVES: The purpose of this pilot study was to determine the benefits of a 12-week computer-based exercise intervention on perceived physical, motivational, and fatigue syndrome and psychological state...
December 1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/29146752/physical-activity-and-cancer-an-umbrella-review-of-the-literature-including-22-major-anatomical-sites-and-770%C3%A2-000-cancer-cases
#14
REVIEW
Leandro Fórnias Machado de Rezende, Thiago Hérick de Sá, Georgios Markozannes, Juan Pablo Rey-López, I-Min Lee, Konstantinos K Tsilidis, John P A Ioannidis, José Eluf-Neto
OBJECTIVE: To provide an overview of the breadth and validity of claimed associations between physical activity and risk of developing or dying from cancer. DESIGN: Umbrella review. DATA SOURCES: We searched Medline, Embase, Cochrane Database and Web of Science. ELIGIBILITY CRITERIA FOR SELECTING STUDIES: Systematic reviews about physical activity and cancer incidence and cancer mortality in different body sites among general population...
November 16, 2017: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/29145731/decline-of-physical-activity-in-terminally-ill-patients-could-be-useful-for-predicting-short-term-survival
#15
Hiroki Yasui, Satoru Iwase, Keisuke Ariyoshi, Masanori Nojima, Kazuhiro Yoshiuchi
BACKGROUND: Although it is recommended that all terminally ill patients receive advance care planning (ACP), this is occasionally challenging because of the difficulty in predicting survival. There are some indexes for predicting survival, but few are accurate, especially at the terminal stages of illness. METHODS: Twenty-two patients at the terminal stages of cancer were retrospectively analyzed. We assessed their physical activity and condition using activities of daily living (ADL) scores for 1 month before the death...
January 1, 2017: American Journal of Hospice & Palliative Care
https://www.readbyqxmd.com/read/29144185/rest-activity-circadian-rhythm-and-sleep-quality-in-patients-with-binge-eating-disorder
#16
E Roveda, A Montaruli, L Galasso, C Pesenti, E Bruno, P Pasanisi, M Cortellini, S Rampichini, S Erzegovesi, A Caumo, F Esposito
Recent findings suggest that altered rest-activity circadian rhythms (RARs) are associated with a compromised health status. RARs abnormalities have been observed also in several pathological conditions, such as cardiovascular, neurological, and cancer diseases. Binge eating disorder (BED) is the most common eating disorder, with a prevalence of 3.5% in women and 2% in men. BED and its associate obesity and motor inactivity could induce RARs disruption and have negative consequences on health-related quality of life...
November 16, 2017: Chronobiology International
https://www.readbyqxmd.com/read/29144172/disruptions-in-sleep-wake-cycles-in-community-dwelling-cancer-patients-receiving-palliative-care-and-their-correlates
#17
Marie Solange Bernatchez, Josée Savard, Hans Ivers
Significant disruptions in sleep-wake cycles have been found in advanced cancer patients in prior research. However, much remains to be known about specific sleep-wake cycle variables that are impaired in patients with a significantly altered performance status. More studies are also needed to explore the extent to which disrupted sleep-wake cycles are related to physical and psychological symptoms, time to death, maladaptive sleep behaviors, quality of life and 24-h light exposure. This study conducted in palliative cancer patients was aimed at characterizing patients' sleep-wake cycles using various circadian parameters (i...
November 16, 2017: Chronobiology International
https://www.readbyqxmd.com/read/29143608/physical-activity-in-the-prevention-of-human-diseases-role-of-epigenetic-modifications
#18
REVIEW
Elisa Grazioli, Ivan Dimauro, Neri Mercatelli, Guan Wang, Yannis Pitsiladis, Luigi Di Luigi, Daniela Caporossi
Epigenetic modification refers to heritable changes in gene function that cannot be explained by alterations in the DNA sequence. The current literature clearly demonstrates that the epigenetic response is highly dynamic and influenced by different biological and environmental factors such as aging, nutrient availability and physical exercise. As such, it is well accepted that physical activity and exercise can modulate gene expression through epigenetic alternations although the type and duration of exercise eliciting specific epigenetic effects that can result in health benefits and prevent chronic diseases remains to be determined...
November 14, 2017: BMC Genomics
https://www.readbyqxmd.com/read/29143545/taz-responds-to-fluid-shear-stress-to-regulate-the-cell-cycle
#19
Hyun Jung Lee, Adesuwa Ewere, Miguel F Diaz, Pamela L Wenzel
Physical forces associated with tumor growth and drainage alter cancer cell invasiveness and metastatic potential. We previously showed that fluid frictional force, or shear stress, typical of lymphatic flow induces YAP1/TAZ activation in prostate cancer cells to promote motility dependent upon YAP1 but not TAZ. Here, we show that shear stress elevates TAZ protein levels and promotes TAZ nuclear localization. Increased TAZ activity drives increased DNA synthesis and induces AMOTL2, ANKRD1, and CTGF gene transcription independently of YAP1...
November 16, 2017: Cell Cycle
https://www.readbyqxmd.com/read/29141851/a-review-of-physical-activity-and-circulating-mirna-expression-implications-in-cancer-risk-and-progression
#20
Suzanne Dufresne, Amélie Rebillard, Paola Muti, Christine M Friedenreich, Darren R Brenner
The role of circulating microRNAs (c-miRNAs) in carcinogenesis has garnered considerable scientific interest. MiRNAs may contribute actively to cancer development and progression, making them potential targets for cancer prevention and therapy. Lifestyle factors such as physical activity (PA) have been shown to alter c-miRNAs expression but the subsequent impact on cancer risk and prognosis is unknown. To provide a better understanding of how PA reduces the risk of cancer incidence and improves patient outcomes, we conducted a review of the impact of PA on c-miRNAs expression, which includes a comprehensive synthesis of studies examining the impacts of acute and chronic exercise on expression of c-miRNAs...
November 15, 2017: Cancer Epidemiology, Biomarkers & Prevention
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