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Nirav Patel, Justine Pierson, Timothy Lee, Bruce Mast, Bernard T Lee, Irene Estores, Dhruv Singhal
BACKGROUND: Integrative medicine (IM) is currently used by 40% of Americans. Our objective is to examine the prevalence and perception of IM utilization in patients being evaluated for elective plastic surgery. METHODS: In July 2014, 402 consecutive patients presenting to plastic surgery clinics at the University of Florida, Veterans Affairs (VA), and Private Practices in Gainesville, Florida were requested to complete a survey regarding utilization of and attitudes towards IM...
October 17, 2016: Annals of Plastic Surgery
Chris S Ivanoff, Krassimira Yaneva, Diana Luan, Bogomil Andonov, Reena R Kumar, Anirudha Agnihotry, Athena E Ivanoff, Dimitrios Emmanouil, Luiz Evaristo Ricci Volpato, Filip Koneski, Ilijana Muratovska, Huda A Al-Shehri, Sara M Al-Taweel, Michele Daly
BACKGROUND: Training culturally competent graduates who can practice effectively in a multicultural environment is a goal of contemporary dental education. The Global Oral Health Initiative is a network of dental schools seeking to promote global dentistry as a component of cultural competency training. OBJECTIVE: Before initiating international student exchanges, a survey was conducted to assess students' awareness of global dentistry and interest in cross-national clerkships...
October 18, 2016: International Dental Journal
Anna Prigitano, Caterina Cavanna, Marco Passera, Cristina Ossi, Eugenio Sala, Gianluigi Lombardi, Anna Grancini, Concetta De Luca, Simone Bramati, Marina Gelmi, Milvana Tejada, Romualdo Grande, Claudio Farina, Fabiola Lallitto, Anna Maria Tortorano
PURPOSE: The aim of this study was to monitor recent changes in the epidemiology of candidemia and in the antifungal susceptibility profiles of Candida isolates in one Italian region (Lombardy) in 2014-2015 in comparison with two other studies performed in the same area in 1997-1999 and in 2009. METHODS: A laboratory-based surveillance was conducted in 11 microbiology laboratories. Identification of Candida isolates from 868 episodes and antifungal susceptibility testing (YeastOne) was performed locally...
October 17, 2016: Infection
Jennifer Muir, Melyssa Aronson, Mary-Jane Esplen, Aaron Pollett, Carol J Swallow
BACKGROUND: Hereditary diffuse gastric cancer (HDGC) syndrome is caused by germline mutations in the CDH1 gene and carries a lifetime gastric cancer risk of approximately 70 % in men and 56 % in women. Current consensus guidelines recommend that people of age ≥20 who harbor a CDH1 mutation undergo prophylactic total gastrectomy (PTG). However, the decision to proceed with a major visceral resection for prophylactic reasons may be difficult, especially since long-term outcomes are not well defined...
October 17, 2016: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
Dorothy Kammerer-Doak, Kamil Svabik, Tony Bazi
INTRODUCTION AND HYPOTHESIS: Members of the International Urogynecological Association (IUGA) come from different geographic locations and practice settings. A member survey regarding practice patterns provides valuable information for practitioners and researchers alike, and allows the IUGA to discover areas to focus on education and information dissemination. METHODS: A questionnaire was developed by the IUGA Research and Development committee and distributed electronically to IUGA surgeons...
October 17, 2016: International Urogynecology Journal
Mun Ki Min, Seok Ran Yeom, Ji Ho Ryu, Yong In Kim, Maeng Real Park, Sang Kyoon Han, Seong Hwa Lee, Sung Wook Park, Soon Chang Park
OBJECTIVE: We compared training using a voice advisory manikin (VAM) with an instructor-led (IL) course in terms of acquisition of initial cardiopulmonary resuscitation (CPR) skills, as defined by the 2010 resuscitation guidelines. METHODS: This study was a randomized, controlled, blinded, parallel-group trial. We recruited 82 first-year emergency medical technician students and distributed them randomly into two groups: the IL group (n=41) and the VAM group (n=37)...
September 2016: Clin Exp Emerg Med
J Cohen, C Andre, P Mozer
Prostate cancer is the first cancer and the second cause of cancer death in men in France. It is now a major public health issue, particularly given the increase of life expectancy. If screening is based on blood PSA and clinical examination (DRE), diagnosis requires the histological analysis of prostate samples. In current clinical routine, these biopsies are performed by endorectal through ultrasound guidance. In most cases, the cancer is not visible in the ultrasound image and the latter is used to make a dozen samples (or core), distributed as best as possible in the prostate...
October 14, 2016: Progrès en Urologie
Timo-Kolja Pförtner, Irene Moor
Background: The relationship between socioeconomic status and health is explained by the unequal distribution of material, psychosocial and behavioral factors. The aim of this study is to analyze the relative contribution of these factors for the association between income and different indicators of health and diseases. Method: Analyses were based on data from the "German Socioeconomic Panel (GSOEP)" in 2011. We estimated the relative contribution of material, psychosocial and behavioral factors in income-related inequalities in health by logistic mediator analyses focusing on following outcomes: self-rated health, diabetes, cardiac disease, sleep disorder, joint diseases, depression and chronical back trouble...
October 17, 2016: Psychotherapie, Psychosomatik, Medizinische Psychologie
Xiang Lv, Zhuoyun Li, Jiagang Wu, Dingquan Xiao, Jianguo Zhu
It is a tough issue to develop dense and water resistant KNbO3 ceramics duo to high evaporation and hygroscopicity of K2O. Here, KNbO3: xZnO composite ceramics were used to successfully solve this problem, where ZnO particles were randomly distributed into KNbO3 matrix. The addition of ZnO hardly affects phase structure of KNbO3, and moreover the enhancement of electrical properties, thermal stability and aging characteristics was observed in KNbO3: xZnO composite ceramics. The composites possessed the maximum d33 of 120±5 pC/N, which is superior to pure KNbO3 (d33=80 pC/N)...
October 17, 2016: ACS Applied Materials & Interfaces
Stephen Burgess, Jack Bowden, Tove Fall, Erik Ingelsson, Simon G Thompson
Mendelian randomization investigations are becoming more powerful and simpler to perform, due to the increasing size and coverage of genome-wide association studies and the increasing availability of summarized data on genetic associations with risk factors and disease outcomes. However, when using multiple genetic variants from different gene regions in a Mendelian randomization analysis, it is highly implausible that all the genetic variants satisfy the instrumental variable assumptions. This means that a simple instrumental variable analysis alone should not be relied on to give a causal conclusion...
September 26, 2016: Epidemiology
Ahmed E Arafa, Amel A Mohamed, Manal M Anwar
BACKGROUND AND PURPOSE: Blood-borne pathogens (BBP) [hepatitis B virus (HBV), hepatitis C virus (HCV), and HIV] pose a considerable infectious risk for nurses, resulting in unwanted health outcomes and psychological stress. AIM OF THE WORK: This study aimed to assess the knowledge and practices of nurses and define administrative roles regarding in BBP and infection control (IC) measures in selected Beni-Suef Hospitals. PARTICIPANTS AND METHODS: A cross-sectional study was carried out from December 2014 to January 2015 using a self-administered questionnaire...
September 2016: Journal of the Egyptian Public Health Association
Kathryn E Mansfield, Julius Sim, Peter Croft, Kelvin P Jordan
Chronic widespread pain (CWP) is common in the general population. It is unclear how people reporting this problem present in primary care; they may regularly consult for regional pains without being recognized as having a generalized condition. Our objectives were to determine the prevalence of people consulting in primary care for musculoskeletal conditions in different body regions on different occasions (recurrent regional pain consultation), the proportion with diagnosed generalized pain and survey-reported widespread pain, and if they have features characteristic of CWP...
September 29, 2016: Pain
Ivana Tlak Gajger, Marina Kosanović, Nina Bilandžić, Marija Sedak, Bruno Čalopek
Beeswax foundations are a necessary material in intensive modern beekeeping. Heavy metals can accumulate in these foundations for decades, as it is a common beekeeping practice to recycle wax. Beeswax samples were analysed using GFAAS for As, Cd, Pb, and Hg concentrations during the production of beeswax foundations using casting technology with a prolonged cooling and sedimentation phase. Significant differences were determined in the concentrations of As, Cd, Pb (p<0.01, all), and Hg (p<0.05) between the three levels of wax in a double-walled steel casting container and comb foundations (CF) during the processing stage...
September 1, 2016: Arhiv za Higijenu Rada i Toksikologiju
Saeed Izadi, Ramu Anandakrishnan, Alexey V Onufriev
Molecular Dynamics (MD) simulations based on the implicit solvent generalized Born (GB) models can provide significant computational advantages over the traditional explicit solvent simulations. However, the standard GB becomes prohibitively expensive for all-atom simulations of large structures; the model scales poorly, ~n^2, with the number of solute atoms. Here we combine our recently developed Optimal Point Charge Approximation (OPCA) with the Hierarchical Charge Partitioning (HCP) approximation to present an ~n log n multi-scale, yet fully atomistic, GB model (GB-HCPO)...
October 17, 2016: Journal of Chemical Theory and Computation
David M Dror, Arpita Chakraborty, Atanu Majumdar, Pradeep Panda, Ruth Koren
BACKGROUND & OBJECTIVES: The evidence-base of the impact of community-based health insurance (CBHI) on access to healthcare and financial protection in India is weak. We investigated the impact of CBHI in rural Uttar Pradesh and Bihar s0 tates of India on insured households' self-medication and financial position. METHODS: Data originated from (i) household surveys, and (ii) the Management Information System of each CBHI. Study design was "staggered implementation" cluster randomized controlled trial with enrollment of one-third of the treatment group in each of the years 2011, 2012 and 2013...
June 2016: Indian Journal of Medical Research
Laetitia Claverie, Anne Ille, Pierre Moretto
The aim of this study was to determine the distribution of discrete sensors under the footprint for accurate plantar pressure analyses. For this purpose, two different sensor layouts have been tested and compared, to determine which was the most accurate to monitor plantar pressure with wireless devices in research and/or clinical practice. Ten healthy volunteers participated in the study (age range: 23-58 years). The barycenter of pressures (BoP) determined from the plantar pressure system (W-inshoe®) was compared to the center of pressures (CoP) determined from a force platform (AMTI) in the medial-lateral (ML) and anterior-posterior (AP) directions...
October 10, 2016: Medical Engineering & Physics
Maxine de la Cruz, Akhila Reddy, Vishidha Balankari, Margeaux Epner, Susan Frisbee-Hume, Jimin Wu, Diane Liu, Sriram Yennurajalingam, Hilda Cantu, Janet Williams, Eduardo Bruera
BACKGROUND: Improper use, storage, and disposal of prescribed opioids can lead to diversion or accidental poisoning. Our previous study showed a large proportion of cancer patients have unsafe opioid practices. Our objective was to determine whether an improvement occurred in the patterns of use, storage, and disposal of opioids among cancer outpatients after the implementation of a patient educational program. PATIENTS AND METHODS: Our palliative care (PC) clinic provides every patient with educational material (EM) on safe opioid use, storage, and disposal every time they receive an opioid prescription...
October 14, 2016: Oncologist
Guillem Rigaill, Sandrine Balzergue, Véronique Brunaud, Eddy Blondet, Andrea Rau, Odile Rogier, José Caius, Cathy Maugis-Rabusseau, Ludivine Soubigou-Taconnat, Sébastien Aubourg, Claire Lurin, Marie-Laure Martin-Magniette, Etienne Delannoy
Numerous statistical pipelines are now available for the differential analysis of gene expression measured with RNA-sequencing technology. Most of them are based on similar statistical frameworks after normalization, differing primarily in the choice of data distribution, mean and variance estimation strategy and data filtering. We propose an evaluation of the impact of these choices when few biological replicates are available through the use of synthetic data sets. This framework is based on real data sets and allows the exploration of various scenarios differing in the proportion of non-differentially expressed genes...
October 14, 2016: Briefings in Bioinformatics
Tawanda Gumbo, Mamodikoe K Makhene, James A Seddon
There has been a recent expansion of preclinical models to predict the efficacy of regimens to treat adults with tuberculosis. Despite increasing global interest in childhood tuberculosis, these same tools have not been employed to develop pediatric regimens. Children differ from adults in bacillary burden, spectrum of disease, the metabolism and distribution of antituberculosis drugs, and the toxicity experienced. The studies documented in this series describe a proof-of-concept approach to pediatric regimen development...
November 1, 2016: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Anika Thielmann, Biljana Gerasimovska-Kitanovska, Krzysztof Buczkowski, Tuomas H Koskela, Vildan Mevsim, Slawomir Czachowski, Ferdinando Petrazzuoli, Marija Petek-Šter, Heidrun Lingner, Robert D Hoffman, Selda Tekiner, Juliette Chambe, Tamer Edirne, Kathryn Hoffmann, Enzo Pirrotta, Ayşegül Uludağ, Hülya Yikilkan, Sanda Kreitmayer Pestic, Andrzej Zielinski, Clara Guede Fernández, Birgitta Weltermann
Background. Patients use self-care to relieve symptoms of common colds, yet little is known about the prevalence and patterns across Europe. Methods/Design. In a cross-sectional study 27 primary care practices from 14 countries distributed 120 questionnaires to consecutive patients (≥18 years, any reason for consultation). A 27-item questionnaire asked for patients' self-care for their last common cold. Results. 3,074 patients from 27 European sites participated. Their mean age was 46.7 years, and 62.5% were females...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
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