keyword
MENU ▼
Read by QxMD icon Read
search

toxoplasmosis diagnosis

keyword
https://www.readbyqxmd.com/read/29663900/congenital-toxoplasmosis-in-tunisia-prenatal-and-neonatal-diagnosis-and-postnatal-follow-up-of-35-cases
#1
Boudaouara Yosr, Aoun Karim, Maatoug Rania, Souissi Olfa, Bouratbine Aïda, Ben Abdallah Rym
Congenital toxoplasmosis (CT) results from transplacental passage of Toxoplasma gondii to the fetus during acute maternal infection. Our study aims to report clinical and biological patterns of 35 cases of CT diagnosed at the department of the Parasitology of the Pasteur Institute of Tunis and to access the performance of prenatal and early postnatal diagnosis techniques. Serological screening of maternal infection was performed by Immunoglobulin (Ig) M and IgG detection and IgG avidity determination. Prenatal diagnosis was based on both Toxoplasma DNA detection in the amniotic fluid and monthly ultrasound examinations...
April 16, 2018: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29652970/-congenital-toxoplasmosis-serology-pcr-parasite-isolation-and-molecular-characterization-of-toxoplasma-gondii
#2
Liliana Carral, Federico Kaufer, Lais Pardini, Ricardo Durlach, Gastón Moré, María C Venturini, Cristina Freuler
Congenital toxoplasmosis diagnosis in the newborn is a very important issue due to the need for early treatment to prevent future sequels. Aim To compare available methods at the institution for the diagnosis of congenital toxoplasmosis. Material and Methods In this study we have evaluated the different diagnostic tests used in 67 congenital exposed newborns, including serological tests, PCR, parasite isolation and molecular characterization. Results The ISAGA IgM and IgA tests showed sensitivity (Se) of 87 and 91%, respectively, and specificity (Sp) of 100%...
2018: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
https://www.readbyqxmd.com/read/29644250/symptomatic-acute-toxoplasmosis-in-returning-travelers
#3
Andrés F Henao-Martínez, Carlos Franco-Paredes, Alan G Palestine, Jose G Montoya
We report a family who acquired acute toxoplasmosis after a trip to Central America. One member developed severe clinical manifestations including bilateral chorioretinitis, hepatitis, and myocarditis requiring therapy. Symptomatic acute toxoplasmosis is unusual and possesses a diagnostic challenge. We discuss the clinical and epidemiological implications, laboratory diagnosis, and treatment plan.
April 2018: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/29604975/primary-cns-lymphoma-in-hiv-infection
#4
Dieta Brandsma, Jacoline E C Bromberg
Primary CNS lymphoma (PCNSL) has been designated an acquired immune deficiency syndrome (AIDS)-defining disease since 1983 and accounts for up to 15% of non-Hodgkin lymphomas in human immunodeficiency virus (HIV) patients. The majority of HIV patients are Epstein-Barr virus (EBV)-related. The most likely etiology is ineffective immunoregulation of EBV, inducing oncogenic protein expression, and subsequent loss of apoptosis and increased proliferation of lymphocytes. PCNSL generally presents with supratentorial, single or multiple, contrast-enhancing lesions...
2018: Handbook of Clinical Neurology
https://www.readbyqxmd.com/read/29604970/central-nervous-system-infection-with-toxoplasma-gondii
#5
Christina M Marra
Central nervous system infection by Toxoplasma gondii, or Toxoplasma encephalitis, is the most common cause of brain mass lesions in human immunodeficiency virus (HIV)-infected patients. It usually presents as one or more brain abscesses, but it can also cause a diffuse encephalitis or ventriculitis. Individuals who are Toxoplasma immunoglobulin G-seropositive, who have peripheral blood CD4+ T-cell concentrations below 200/μL, are not on antiretroviral therapy, and are not taking trimethoprim-sulfamethoxazole to prevent Pneumocystis pneumonia, are at particular risk for Toxoplasma encephalitis...
2018: Handbook of Clinical Neurology
https://www.readbyqxmd.com/read/29604343/use-of-polymerase-chain-reaction-pcr-in-the-diagnosis-of-congenital-toxoplasmosis
#6
C Loveridge-Easther, Anne-Marie Yardley, Brenda Breidenstein
No abstract text is available yet for this article.
March 28, 2018: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/29588907/disseminated-toxoplasmosis-in-a-patient-with-advanced-acquired-immunodeficiency-syndrome
#7
Ricardo Garcia Pastorello, Anderson da Costa Lino Costa, Marcio Valente Yamada Sawamura, Antonio Carlos Nicodemo, Amaro Nunes Duarte-Neto
Extracerebral toxoplasmosis, with pulmonary involvement and shock, is a rare form of toxoplasmosis in patients with advanced AIDS. It can mimic pneumocystosis, histoplasmosis, and disseminated tuberculosis, and should be considered in the differential diagnosis of causes of respiratory failure and fulminant disease in this group of individuals, especially in areas where the Toxoplasma gondii infection is highly prevalent and in those without proper use of antimicrobial prophylaxis. We report the case of a 46-year-old male patient who presented to the emergency department with uremia, requiring urgent dialysis...
January 2018: Autopsy & case reports
https://www.readbyqxmd.com/read/29583086/dual-infection-of-the-central-nervous-system-caused-by-cryptococcus-and-toxoplasma-in-a-patient-with-aids-a-case-report-and-literature-review
#8
Jose Armando Gonzales Zamora
Dual infection of the central nervous system secondary to Cryptococcus and Toxoplasma is very uncommon, even in the setting of acquired immunodeficiency syndrome (AIDS). We report the case of a 52-year-old patient who was admitted with multiple cranial nerve deficits. Magnetic resonance imaging showed supratentorial and infratentorial enhancing lesions. He was newly diagnosed with HIV infection with a CD4 count of 59 cells/uL and HIV viral load of 299,619 copies/mL. Diagnosis of Cryptococcus meningitis was made by Cryptococcal antigen in cerebrospinal fluid (CSF)...
March 27, 2018: Acta Clinica Belgica
https://www.readbyqxmd.com/read/29582812/changing-uveitis-patterns-in-south-india-comparison-between-two-decades
#9
Jyotirmay Biswas, Ranju Kharel Sitaula, Priyansha Multani
Purpose: Changing pattern of uveitis in a subset of a population is an important ocular health indicator. Methods: A comparative study was done between uveitis patients of 2013 and 1995 using two proportions Z-test. Results: In 2013, 352 new uveitis cases were examined. Males 56%, females 44%; unilateral 30.4%; bilateral in 69.6%. A specific diagnosis achieved in 66.2%. Anterior uveitis was seen in 35.22%, intermediate uveitis in 30.11%, posterior uveitis in 25%, and panuveitis in 9...
April 2018: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29580227/first-case-report-of-m1-macrophage-polarization-in-an-untreated-symptomatic-patient-with-toxoplasmosis
#10
Graziano De Luca, Chiara Di Lisio, Giuseppe Lattanzio, Tommaso D'Antuono, Marcella Liberatore, Francesca Bianca Aiello
BACKGROUND: In immunocompetent patients, acute toxoplasmosis is usually asymptomatic. We identified M1 macrophages in a case of symptomatic acute Toxoplasma gondii infection that resolved without treatment. M1 macrophages have been demonstrated in animal models of toxoplasmosis, but not in humans. CASE PRESENTATION: A 63-year-old woman presented with laterocervical and axillary bilateral lymphadenopathy. Her anamnesis defined an episode of high fever and prolonged asthenia 4 months previously, which suggested an infectious disease...
March 27, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29573417/what-do-anti-t-gondii-iga-and-igg-subclasses-in-human-saliva-indicate
#11
Irma Cañedo-Solares, Fernando Gómez-Chávez, Héctor Luna-Pastén, Luz Belinda Ortiz-Alegría, Yevel Flores-García, Ricardo Figueroa-Damián, Claudia Astrid Macedo-Romero, Dolores Correa
Diagnostic tests for toxoplasmosis are based on serological techniques due to their high sensitivity. Some IgG subclasses are related to clinical outcome in the congenital form. In this work, we determined the levels of IgG, IgA, IgG1, IgG2, IgG3 and IgG4 anti-Toxoplasma gondii antibodies in paired saliva and serum samples from 91 women by indirect ELISA using a crude extract of the RH strain. The levels of IgA, IgG2, IgG3 and IgG4 antibodies and, to a lesser extent, IgG1, did not correlate between saliva and serum, i...
March 24, 2018: Parasite Immunology
https://www.readbyqxmd.com/read/29563388/prevalence-of-opportunistic-infections-and-causes-of-death-among-hospitalized-hiv-infected-patients-in-sichuan-china
#12
Wenwen Pang, Pengcheng Shang, Qingfeng Li, Jiao Xu, Lei Bi, Jing Zhong, Xiaofang Pei
Opportunistic infections (OIs) are the most significant complication of human immunodeficiency virus (HIV) infection. The prevalence of OIs differs among various countries in part due to different climates and socio-economic conditions. We, therefore, carried out the retrospective study at the Public Health Clinical Center of Chengdu, Sichuan to comprehensively investigate the prevalence of OIs, predictors of OIs, and risk factors for in-hospital death among HIV-infected patients. Sichuan in West China is characterized by the largest population living with HIV/Acquired immunodeficiency syndrome (AIDS) across China...
March 2018: Tohoku Journal of Experimental Medicine
https://www.readbyqxmd.com/read/29559329/molecular-characterization-of-babesia-microti-seroreactive-antigen-5-1-1-and-development-of-rapid-detection-methods-for-anti-b-microti-antibodies-in-serum
#13
Yu Chun Cai, Fen Wu, Wei Hu, Jiaxu Chen, Shao Hong Chen, Bin Xu, Yan Lu, Lin Ai, Chun Li Yang, Shimin Zhao
Babesiosis has become a new global threat impacting human health, and most human babesiosis cases are caused by Babesia microti. Until now few antigens of B. microti have been described which can be used for the diagnosis of human babesiosis. In the present study, we report on the bioinformatic analysis, cloning and expression of the sequence encoding the B. microti seroreactive antigen 5-1-1 to investigate its potential incorporation in serologic diagnostic tools for babesiosis. Bioinformatic analysis and recombinant gene expression were performed to molecularly characterize seroreactive antigen 5-1-1...
March 17, 2018: Acta Tropica
https://www.readbyqxmd.com/read/29536166/seroprevalence-of-toxoplasma-gondii-in-iberian-pig-sows
#14
Alba Pablos-Tanarro, Luis Miguel Ortega-Mora, Antonio Palomo, Francisco Casasola, Ignacio Ferre
The objective of the present study was to investigate the seroprevalence of Toxoplasma gondii infection in Iberian sows reared in extensive and intensive management conditions and to compare two serologic techniques used for diagnosis. In addition, some possible risk factors associated with the presence of serum antibodies to T. gondii were also studied. Serum samples were collected from 2492 Iberian sows on 14 pig farms. Three types of management systems were included, traditional extensive outdoor farms (five farms), intensive farms with outdoor access (n = 4), and conventional intensive indoor farms (n = 5)...
March 13, 2018: Parasitology Research
https://www.readbyqxmd.com/read/29513626/diagnostic-value-of-positive-findings-of-toxoplasma-gondii-specific-immunoglobulin-m-serum-antibody-in-uveitis-patients-to-confirm-ocular-toxoplasmosis
#15
Sung Who Park, So Hee Kim, Han Jo Kwon, Seung Min Lee, Ik Soo Byon, Ji Eun Lee
PURPOSE: To assess the value of positive immunoglobulin (Ig) M serum antibody (Ab) findings in uveitis patients. METHODS: We reviewed medical records of patients who had a positive serological test for Toxoplasma gondii-specific IgM Ab. Their clinical data, including history, demographic characteristics, laboratory findings, clinical findings, treatment outcomes, and recurrences, were reviewed retrospectively. RESULTS: Of 2919 uveitis patients who underwent a serological test for suspected ocular toxoplasmosis (OT), 18 presented with positive Ig M results...
March 7, 2018: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/29476868/a-new-lamp-based-assay-for-the-molecular-diagnosis-of-toxoplasmosis-comparison-with-a-proficient-pcr-assay
#16
Emmanuelle Varlet-Marie, Yvon Sterkers, Marina Perrotte, Patrick Bastien
Toxoplasmosis is generally a benign infection caused by the protozoan parasite Toxoplasma gondii but can have severe consequences in fetuses of mothers infected during pregnancy (congenital toxoplasmosis) and immunocompromised individuals. PCR-based diagnostic tests have become crucial for its diagnosis. However, this molecular diagnosis essentially relies upon laboratory-developed methods and suffers from a lack of standardization, leading to great variation in methods and performance among laboratories. With the need for accreditation of clinical microbiological laboratories, the use of commercial PCR kits has become an attractive alternative; but thorough evaluation of newly commercialized kits by proficient groups is necessary before any recommendation can be made to parasitology laboratories by health authorities or learned societies...
February 22, 2018: International Journal for Parasitology
https://www.readbyqxmd.com/read/29473896/congenital-toxoplasmosis-a-plea-for-a-neglected-disease
#17
Martine Wallon, François Peyron
Maternal infection by Toxoplasma gondii during pregnancy may have serious consequences for the fetus, ranging from miscarriage, central nervous system involvement, retinochoroiditis, or subclinical infection at birth with a risk of late onset of ocular diseases. As infection in pregnant women is usually symptomless, the diagnosis relies only on serological tests. Some countries like France and Austria have organized a regular serological testing of pregnant women, some others have no prenatal program of surveillance...
February 23, 2018: Pathogens
https://www.readbyqxmd.com/read/29458884/late-onset-fetal-bilateral-pleural-effusions-associated-with-down-syndrome
#18
Shih-Ting Lai, Chih-Ping Chen, Chen-Ju Lin, Chin Yuan Hsu, Peih-Shan Wu, Chen Chi Lee, Chen Wen Pan, Wayseen Wang
OBJECTIVE: We present two cases of late-onset bilateral fetal pleural effusions associated with fetal Down syndrome. CASE REPORTS: Case 1. A 33-year-old Vietnamese woman had undergone regular sonographic examinations since 23 weeks of gestation and no abnormality had been noted. However, bilateral moderate pleural effusions were found at 33 weeks of gestation, and massive pleural effusion, ascites and polyhydramnios developed at 34 weeks of gestation. Aspiration of the pleural effusion was subsequently performed...
February 2018: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29452292/prevalence-risk-factors-and-genetic-characterization-of-toxoplasma-gondii-in-sick-pigs-and-stray-cats-in-jiangsu-province-eastern-china
#19
Zhao-Feng Hou, Shi-Jie Su, Dan-Dan Liu, Le-le Wang, Chuan-Li Jia, Zhen-Xing Zhao, Yi-Fei Ma, Qiao-Qiao Li, Jin-Jun Xu, Jian-Ping Tao
Toxoplasma gondii is an obligate intracellular parasitic protozoan with a worldwide distribution. The parasites in edible tissues of pigs and oocysts from cats are the major sources of T. gondii infection in humans. However, there are no data from sick pigs in veterinary clinics or from stray cats in Jiangsu Province, eastern China. In total, biological samples from 141 sick pigs and 64 stray cats were collected from this region. The rate of T. gondii infection in sick pigs was 46.81% using a polymerase chain reaction (PCR), and the overall prevalence of toxoplasmosis in stray cats was 34...
February 13, 2018: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/29398460/a-novel-chemiluminescent-immunoassay-based-on-original-acridinium-ester-labels-as-better-solution-for-diagnosis-of-human-toxoplasmosis-than-conventional-elisa-test
#20
Lucyna Holec-Gąsior, Bartłomiej Ferra, Justyna Czechowska, Illia E Serdiuk, Karol Krzymiński
Toxoplasma gondii infection is one of the most common human zoonosis. Laboratory diagnosis of this disease is mainly based on the results of serological methods detecting specific antibodies in the patient's sera. In this study we aimed to evaluate the performance of a chemiluminescence immunoassay (CLIA) based on the use of a novel immunochemical reagent in the form of the conjugate of original acridinium label (AL) attached to secondary antibody (IgG-AL) and SAG2-GRA1-ROP1L chimeric antigen for T. gondii specific antibodies detection...
January 6, 2018: Diagnostic Microbiology and Infectious Disease
keyword
keyword
68484
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"