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acute coronary sindromes

Alexandre de Matos Soeiro, Pedro Gabriel Melo de Barros E Silva, Eduardo Alberto de Castro Roque, Aline Siqueira Bossa, Maria Cristina César, Sheila Aparecida Simões, Mariana Yumi Okada, Tatiana de Carvalho Andreucci Torres Leal, Fátima Cristina Monteiro Pedroti, Múcio Tavares de Oliveira
Background: Recent studies have shown fondaparinux's superiority over enoxaparin in patients with non-ST elevation acute coronary syndrome (ACS), especially in relation to bleeding reduction. The description of this finding in a Brazilian registry has not yet been documented. Objective: To compare fondaparinux versus enoxaparin in in-hospital prognosis of non-ST elevation ACS. Methods: Multicenter retrospective observational study. A total of 2,282 patients were included (335 in the fondaparinux group, and 1,947 in the enoxaparin group) between May 2010 and May 2015...
September 2016: Arquivos Brasileiros de Cardiologia
Francesco Fattirolli, Alessandra Pratesi
Cardiac rehabilitation in the elderly today often represents a utopia. The international scientific literature takes little into account this type of prescription for old people, although they represent a large and growing proportion of cardiac patients, with acute coronary syndrome or heart failure, which we have to manage in everyday life. Furthermore, interventions of health education, clinical follow up, rehospitalisation prevention and prescription of tailored exercise, are sometimes more necessary in this kind of patients, given the presence of multimorbidity, functional dependence, frailty, sarcopenia, social neglect...
June 22, 2016: Monaldi Archives for Chest Disease, Archivio Monaldi Per le Malattie del Torace
Marco Ambrosetti, Roberto F E Pedretti, Mario Facchini, Gabriella Malfatto, Salvatore Pio Riccobono, Oreste Febo, Tommaso Diaco
In the present work, the current activities of Cardiovascular Rehabilitation and Prevention (CRP) in the ambulatory setting of the Lombardy Region (Italy) are described. Based on the 2012 Legislation, ambulatory CRP is delivered by means of three programme categories (MAC 6, 7, and 8) with different degrees of intensity. The patient evaluation of global cardiovascular/clinical risk, comorbidity, and disability is the cornerstone for MAC prescription. Following the organization of MAC activities, a survey on 327 patients was carried out by the regional network of the Italian Society of Cardiovascular Rehabilitation (GICR-IACPR)...
2016: Monaldi Archives for Chest Disease, Archivio Monaldi Per le Malattie del Torace
Oriol Alegre, Albert Ariza-Solé, María T Vidán, Francesc Formiga, Manuel Martínez-Sellés, Héctor Bueno, Juan Sanchís, Ramón López-Palop, Emad Abu-Assi, Àngel Cequier
The incidence of acute coronary syndromes (ACS) is high in the elderly. Despite a high prevalence of frailty and other aging-related variables, little information exists about the optimal clinical management in patients with coexisting geriatric syndromes. The aim of the LONGEVO-SCA registry (Impacto de la Fragilidad y Otros Síndromes Geriátricos en el Manejo y Pronóstico Vital del Anciano con Síndrome Coronario Agudo sin Elevación de Segmento ST) is to assess the impact of aging-related variables on clinical management, prognosis, and functional status in elderly patients with ACS...
July 2016: Clinical Cardiology
Davide Moreira, Bruno Marmelo, Anne Delgado, Luís Nunes, João Pipa, Oliveira Santos
INTRODUCTION AND OBJECTIVES: The aim of this study was to assess the impact of a conservative strategy in non-ST-segment elevation myocardial infarction in patients in the Portuguese Registry of Acute Coronary Syndromes. METHODS: The 3780 patients included in the study over a three-year period were divided into three groups: group 1, patients treated by a conservative strategy during hospitalization; group 2, patients who underwent coronary angiography without percutaneous coronary intervention (PCI); and group 3, patients who underwent PCI...
May 2015: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
Jassim Al Suwaidi
Cardiovascular diseases are the leading cause of death, worldwide, with disproportionate representation in low- and middle-income countries (LMICs). The Registro Nacional de los Síndromes Coronarios Agudos II (RENASICA II) investigators reported smoking, hypertension and diabetes were the main risk factors among Mexican patients presenting with ST-elevation myocardial infarction (STEMI). Fibrinolytic therapy was administered to 37%. Primary percutaneous coronary intervention (PPCI) was performed in only 15% of patients...
2014: Global Cardiology Science & Practice
Frederico José Neves Mancuso, Vicente Nicoliello Siqueira, Valdir Ambrósio Moisés, Aécio Flavio Teixeira Gois, Angelo Amato Vincenzo de Paola, Antonio Carlos Camargo Carvalho, Orlando Campos
Background: Cardiovascular urgencies are frequent reasons for seeking medical care. Prompt and accurate medical diagnosis is critical to reduce the morbidity and mortality of these conditions. Objective: To evaluate the use of a pocket-size echocardiography in addition to clinical history and physical exam in a tertiary medical emergency care. Methods: One hundred adult patients without known cardiac or lung diseases who sought emergency care with cardiac complaints were included. Patients with ischemic changes in the electrocardiography or fever were excluded...
October 28, 2014: Arquivos Brasileiros de Cardiologia
Ana Rita Santos, Bruno Cordeiro Piçarra, Margarida Celeiro, Ângela Bento, José Aguiar
INTRODUCTION: Multivessel disease in ST-elevation myocardial infarction (STEMI) is associated with a worse prognosis. A multivessel approach at the time of primary percutaneous coronary intervention (PCI) is the subject of debate. OBJECTIVE: To assess the impact of a multivessel approach on in-hospital morbidity and mortality in patients with STEMI undergoing primary PCI. METHODS: We studied patients from the Portuguese Registry of Acute Coronary Syndromes with STEMI and multivessel disease who underwent primary PCI...
February 2014: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
Úrsulo Juárez-Herrera, Carlos Jerjes-Sánchez
BACKGROUND: Ischemic heart disease is a growing health problem in Latin America. We aimed to analyze risk factors, acute management, and short-term outcome of Mexicans with ST-elevation myocardial infarction (STEMI). HYPOTHESIS: Modifiable risk factors are associated with the occurrence of STEMI in Mexicans, and potentially preventable acute complications are responsible for most short-term deaths. METHODS: Among 8600 patients enrolled in Registro Nacional de los Síndromes Coronarios Agudos II (RENASICA II) with a suspected acute coronary syndrome, we analyzed 4555 patients (56%; age 21-100 y) with confirmed STEMI who presented within 24 hours from symptoms' onset...
May 2013: Clinical Cardiology
David Vivas, Juan C García-Rubira, Esther Bernardo, Dominick J Angiolillo, Patricia Martín, Alfonso Calle-Pascual, Iván Núñez-Gil, Carlos Macaya, Antonio Fernández-Ortiz
Patients with hyperglycemia, an acute coronary syndrome and poor glycemic control have increased platelet reactivity and poor prognosis. However, it is unclear the influence of a tight glycemic control on platelet reactivity in these patients. This is a subanalysis of the CHIPS study. This trial randomized patients with hyperglycemia to undergo an intensive glucose control (target blood glucose 80-120 mg/dL), or conventional glucose control (target blood glucose <180 mg/dL). We analyzed platelet function at discharge on the subgroup of patients with poor glycemic control, defined with admission levels of HbA1c higher than 6...
February 2013: Journal of Thrombosis and Thrombolysis
Jose F Diaz, Rosa Cardenal, Antonio Gomez-Manchero, Carlos Sanchez-Gonzalez
Tirofiban is a nonpeptide tyrosine derivative that together with eptifibatide (both small molecules) and abciximam belongs to the group of glycoprotein IIb/IIIa inhibitors. Though similar to abciximab in that it has a high affinity for the GP IIbIIIa inhibitor receptor, tirofiban dissociates from it much faster tan abciximab, what makes its action reversible in a few hours. Initially used upstream for treatment of patients with non ST-elevation acute coronary síndromes, recent evidence has shown its role as adjuntive therapy in patients with ST-elevation acute myocardial infarction treated with primary angioplasty when used at a higher dose...
July 1, 2011: Cardiovascular & Hematological Agents in Medicinal Chemistry
David Vivas, Juan C García-Rubira, Esther Bernardo, Dominick J Angiolillo, Patricia Martín, Alfonso Calle-Pascual, Iván Núñez-Gil, Carlos Macaya, Antonio Fernández-Ortiz
OBJECTIVES: Hyperglycaemia has been associated with increased platelet reactivity and impaired prognosis in patients with acute coronary syndrome (ACS). Whether platelet reactivity can be reduced by lowering glucose in this setting is unknown. The aim of this study was to assess the functional impact of intensive glucose control with insulin on platelet reactivity in patients admitted with ACS and hyperglycaemia. METHODS: This is a prospective, randomised trial evaluating the effects of either intensive glucose control (target glucose 80-120 mg/dl) or conventional control (target glucose 180 mg/dl or less) with insulin on platelet reactivity in patients with ACS and hyperglycaemia...
May 2011: Heart: Official Journal of the British Cardiac Society
José Ferreira Santos, Carlos Aguiar, Cristina Gavina, Pedro Azevedo, João Morais
BACKGROUND: The Portuguese Registry of Acute Coronary Syndromes was established in 2002, with the goal of gathering data on the clinical characteristics, treatment and prognosis of Portuguese patients with acute coronary syndromes (ACS). OBJECTIVE: To report the information collected during the seven years of activity of the Portuguese Registry of ACS (from January 1, 2002 to December 31, 2008). METHODS: The Portuguese Registry of ACS is an observational, prospective and continuous registry, which started on January 1, 2002 and involved 45 Portuguese hospitals...
December 2009: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
Raffaele Bugiardini, Jose L Navarro Estrada, Kjell Nikus, Alistair S Hall, Olivia Manfrini
The major aim of this review was to ascertain whether effective evidence-based treatments for acute coronary syndromes (ACS) are underutilized in women in various geographic areas compared with men. The focus of our review was the relative use of effective treatments in patients with coronary angiographic evidence of obstructive coronary disease, defined as a lumen stenosis >50% of the adjacent non-diseased arterial diameter. We searched MEDLINE, and the Cochrane Database between January 1998 and May 2008...
March 2010: Current Vascular Pharmacology
Jean-Pierre Bassand, Christian W Hamm, Diego Ardissino, Eric Boersma, Andrzej Budaj, Francisco Fernandez-Aviles, Keith A A Fox, David Hasdai, E Magnus Ohman, Lars Wallentin, William Wijns
No abstract text is available yet for this article.
September 2008: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
Ignacio Ferreira-González, Gaietà Permanyer-Miralda, Jaume Marrugat, Magda Heras, José Cuñat, Emilia Civeira, Fernando Arós, Juan J Rodríguez, Pedro L Sánchez, Héctor Bueno
INTRODUCTION AND OBJECTIVES: To investigate the clinical characteristics and treatment of acute coronary syndromes (ACS), and to determine the effects of an early invasive strategy (EIS) in non-ST-elevation ACS (NSTEACS) and of primary percutaneous coronary intervention (PCI) in ST-elevation ACS (STEACS). METHODS: Data were collected prospectively for 9 months during 2004-2005 from 50 hospitals, which were randomly selected according to the level of care provided...
August 2008: Revista Española de Cardiología
V Bertomeu, P Morillas, J R Gonzalez-Juanatey, J Quiles, J Guindo, F Soria, A Llacer, I Lekuona, P Mazón, C Martín-Luengo, L Rodriguez-Padial
OBJECTIVE: A significant proportion of patients with ischemic heart disease have associated peripheral arterial disease (PAD), but many are asymptomatic and this condition remains underdiagnosed. We aimed to study the prevalence of PAD in patients with an acute coronary syndrome (ACS) and to evaluate its influence in hospital clinical outcomes. METHODS: The PAMISCA register is a prospective, multicenter study involving patients >or=40 years old with ACS admitted to selected Spanish hospitals...
August 2008: European Journal of Vascular and Endovascular Surgery
G D De Palma, F Salvatori, S Masone, I Simeoli, M Rega, M Celiento, G Persico
A 58-year old man was admitted to the hospital because of melena. He had a 1-year history of mechanical aortic valve replacement and coronary stent placement because of myocardial infarction and he was taking warfarin and clopidogrel. Esophagogastroduodenoscopy and colonoscopy were negative for bleeding. Capsule endoscopy showed bleeding diffuse angiodysplasia of the small bowel. The patient was treated with octreotide 20 mg, at monthly interval. After 25 months there had been no recurrence of gastrointestinal bleeding...
September 2007: Minerva Gastroenterologica e Dietologica
M Heras, H Bueno, A Bardají, A Fernández-Ortiz, H Martí, J Marrugat
OBJECTIVE: To analyse intensity of treatment of high-risk patients with non-ST elevation acute coronary syndromes (NSTEACS) included in the DESCARTES (Descripción del Estado de los Sindromes Coronarios Agudos en un Registro Temporal Español) registry. PATIENTS AND SETTING: Patients with NSTEACS (n = 1877) admitted to 45 randomly selected Spanish hospitals in April and May 2002 were studied. DESIGN: Patients with ST segment depression and troponin rise were considered high risk (n = 478) and were compared with non-high risk patients (n = 1399)...
November 2006: Heart: Official Journal of the British Cardiac Society
Giampaolo Zoffoli, Francesco Nicolini, Cesare Beghi, Alessandro Maria Budillon, Andrea Agostinelli, Bruno Borrello, Giovanni Cagnoni, Guido Frassetto, Claudio Fragnito, Tiziano Gherli
Coronary artery bypass grafting (CABG) still plays a fundamental role in the management of acute coronary syndromes. The aim of this study is to report the experience of our center in the treatment of patients with acute coronary sindromes without persistent ST elevation urgently operated on with CABG, and to discuss surgical problems related. Two-hundred and six patients were urgently operated on for CABG for acute coronary syndromes without persistent ST-segment elevation from January 2001 to February 2003...
September 2005: Acta Bio-medica: Atenei Parmensis
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