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https://www.readbyqxmd.com/read/28102979/changes-in-salivary-cortisol-during-psychotherapy-for-posttraumatic-stress-disorder-a-pilot-study-in-30-veterans
#1
Sheila A M Rauch, Anthony P King, Israel Liberzon, Rebecca K Sripada
BACKGROUND: Convergent evidence suggests that the hypothalamic-pituitary-adrenal (HPA) axis is disrupted in posttraumatic stress disorder (PTSD) and that HPA axis normalization may be associated with symptom improvement. Thus, the current study was designed to test the association between HPA axis reactivity and treatment response in psychotherapy for PTSD. METHODS: Thirty returning veterans with DSM-IV-TR PTSD were randomly assigned to receive 10 sessions of prolonged exposure therapy or present-centered therapy as part of a previously published randomized clinical trial (2008-2010)...
January 17, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28102978/pretreatment-cardiometabolic-status-in-youth-with-early-onset-psychosis-baseline-results-from-the-tea-trial
#2
Karsten G Jensen, Christoph U Correll, Ditte Rudå, Dea G Klauber, Marie Stentebjerg-Olesen, Birgitte Fagerlund, Jens Richardt Møllegaard Jepsen, Anders Fink-Jensen, Anne Katrine Pagsberg
OBJECTIVE: To describe pretreatment cardiometabolic constitution in children and adolescents with first-episode psychosis (FEP). METHODS: Baseline cardiometabolic assessment was performed in youths aged 12-17 years with FEP entering the Tolerability and Efficacy of Antipsychotics (TEA) trial and matched healthy controls. Patients were included between June 10, 2010, and January 29, 2014. ICD-10 was used as the diagnostic classification system. Cardiometabolic risk markers were compared between patients versus controls and antipsychotic-naive versus antipsychotic-exposed patients...
January 17, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28102961/assessing-the-use-of-4dct-ventilation-in-pre-operative-surgical-lung-cancer-evaluation
#3
Yevgeniy Vinogradskiy, Matthew Jackson, Leah Schubert, Bernard Jones, Richard Castillo, Edward Castillo, Thomas Guerrero, John Mitchell, Chad Rusthoven, Moyed Miften, Brian Kavanagh
PURPOSE: A primary treatment option for lung cancer patients is surgical resection. Patients who have poor lung function prior to surgery are at increased risk of developing serious and life-threatening complications after surgical resection. Surgeons use nuclear medicine ventilation-perfusion (VQ) scans along with pulmonary function test (PFT) information to assess a patient's pre-surgical lung function. The nuclear medicine images and pre-surgery PFTs are used to calculate percent predicted postoperative (%PPO) PFT values by estimating the amount of functioning lung tissue that would be lost with surgical resection...
January 2017: Medical Physics
https://www.readbyqxmd.com/read/28102946/a-portal-dosimetry-dose-prediction-method-based-on-collapsed-cone-algorithm-using-the-clinical-beam-model
#4
J Martínez Ortega, N Gómez González, P Castro Tejero, M Pinto Monedero, N B Tolani, L Núñez Martín, R Sánchez Montero
PURPOSE: Amorphous silicon electronical portal imaging devices (EPIDs) are widely used for dosimetric measurements in Radiation Therapy. The purpose of this work was to determine if a portal dose prediction method can be utilized for dose map calculations based on the linear accelerator model within a commercial treatment planning system (Pinnacle(3) v8.0 m). METHODS: The method was developed for a 6 MV photon beam on the Varian Clinac 21-EX, at a nominal dose rate of 400 MU/min...
January 2017: Medical Physics
https://www.readbyqxmd.com/read/28102945/learning-based-deformable-image-registration-for-infant-mr-images-in-the-first-year-of-life
#5
Shunbo Hu, Lifang Wei, Yaozong Gao, Yanrong Guo, Guorong Wu, Dinggang Shen
PURPOSE: Many brain development studies have been devoted to investigate dynamic structural and functional changes in the first year of life. To quantitatively measure brain development in such a dynamic period, accurate image registration for different infant subjects with possible large age gap is of high demand. Although many state-of-the-art image registration methods have been proposed for young and elderly brain images, very few registration methods work for infant brain images acquired in the first year of life, because of (a) large anatomical changes due to fast brain development and (b) dynamic appearance changes due to white-matter myelination...
January 2017: Medical Physics
https://www.readbyqxmd.com/read/28102939/what-is-the-relationship-between-increased-access-to-haart-relationship-status-and-fertility-decisions-amongst-hiv-positive-women-a-literature-review-and-meta-analysis
#6
REVIEW
Abigail Burgess, Edward Purssell
AIMS AND OBJECTIVES: To investigate the relationship between fertility decisions, to have already had a child or to desire to have one in the future, and the prognostic factors of; access to antiretrovirals, the time since these became widely available (year of the study) and relationship status. BACKGROUND: There have been significant advances in the treatment of Human Immunodeficiency Virus (HIV) with the advent of antiretroviral therapy which has been used to successfully reduce the rate of mother to child transmission; leading researchers to hypothesise that HIV positive women may desire to have children more so now than in the past...
January 19, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28102900/metabolic-theory-predicts-animal-self-thinning
#7
Tomas Jonsson
1.The Metabolic Theory of Ecology (MTE) predicts observed patterns in ecology based on metabolic rates of individuals. The theory is influential but also criticized for a lack of firm empirical evidence confirming MTE's quantitative predictions of processes, e.g. outcome of competition, at population or community level. 2.Self-thinning is a well-known population level phenomenon among plants, but a much less studied phenomenon in animal populations and no consensus exists on what a universal thinning slope for animal populations might be, or if it exists...
January 19, 2017: Journal of Animal Ecology
https://www.readbyqxmd.com/read/28102830/can-exhaled-volatile-organic-compounds-predict-asthma-exacerbations-in-children
#8
Dillys van Vliet, Agnieszka Smolinska, Quirijn Jöbsis, Jean Muris, Philippe Rosias, Jan Dallinga, Edward Dompeling, Frederik van Schooten
Background Asthma control falls short of current goals of asthma management guidelines. Non-invasive monitoring of airway inflammation may help to improve the level of asthma control in children. Aim 1) To identify a set of exhaled volatile organic compounds (VOCs) that is most predictive for an asthma exacerbation in children. 2) To determine the chemical background of predictive VOCs. Methods In an one-year prospective observational study, 96 asthmatic children were studied . At clinical visits with an interval of 2 months, asthma control, fractional exhaled nitric oxide, lung function (FEV1, FEV1/VC) and VOCs in exhaled breath were determined by means of gas chromatography time-of-flight mass spectrometry...
January 19, 2017: Journal of Breath Research
https://www.readbyqxmd.com/read/28102829/absorbed-dose-evaluation-of-auger-electron-emitting-radionuclides-impact-of-input-decay-spectra-on-dose-point-kernels-and-s-values
#9
Nadia Falzone, Boon Lee, José Fernández-Varea, Christiana Kartsonaki, Andrew Stuchbery, Tibor Kibedi, Katherine Vallis
AIM: The aim of this study was to investigate the impact of decay data provided by the newly developed stochastic atomic relaxation model <i>BrIccEmis</i> on dose point kernels (DPKs- radial dose distribution around a unit point source) and <i>S</i>-values (absorbed dose per unit cumulated activity) of 14 Auger electron (AE) emitting radionuclides, namely <sup>67</sup>Ga, <sup>80m</sup>Br, <sup>89</sup>Zr, <sup>90</sup>Nb, <sup>99m</sup>Tc, <sup>111</sup>In, <sup>117m</sup>Sn, <sup>119</sup>Sb, <sup>123</sup>I, <sup>124</sup>I, <sup>125</sup>I, <sup>135</sup>La, <sup>195m</sup>Pt and <sup>201</sup>Tl...
January 19, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28102774/interactions-between-c-reactive-protein-and-traditional-risk-factors-in-predicting-mortality-of-older-adults
#10
Henrik Rudolf, Naemi Wall, Renate Klaassen-Mielke, Ulrich Thiem, Curt Diehm, Hans-Joachim Trampisch, Dietmar Krause
BACKGROUND: Elevated levels of C-reactive protein (CRP) are known to be associated with cardiovascular (CV) morbidity and mortality in older adults, however, there seems to be heterogeneity of this association across subsets of individuals. We aim to assess the effects of interactions between CRP and one of the following traditional CV risk factors regarding all-cause mortality in unselected elderly men and women: age, sex, body mass index, diabetes, and hypertension. PATIENTS AND METHODS: Three hundred and forty-four general practitioners all over Germany enrolled 6,817 unselected participants, aged 65 years or older, and performed thorough examinations, including CRP measurement at baseline (getABI study)...
January 19, 2017: VASA. Zeitschrift Für Gefässkrankheiten
https://www.readbyqxmd.com/read/28102701/the-effect-of-pre-crash-velocity-reduction-on-occupant-response-using-a-human-body-finite-element-model
#11
B Guleyupoglu, J Schap, K D Kusano, F S Gayzik
OBJECTIVE: The objective of this study is to use a validated finite element model of the human body and a certified model of an ATD to evaluate the effect of simulated pre-crash braking on driver kinematics, restraint loads, body loads and computed injury criteria in four commonly-injured body regions. METHODS: The Global Human Body Models Consortium (GHBMC) 50th percentile male occupant (M50-O) and the Humanetics Hybrid-III 50(th) percentile models were gravity settled in the driver position of a generic interior equipped with an advanced three point belt and driver airbag...
January 19, 2017: Traffic Injury Prevention
https://www.readbyqxmd.com/read/28102563/multiscale-modeling-methods-in-biomechanics
#12
REVIEW
Pinaki Bhattacharya, Marco Viceconti
More and more frequently, computational biomechanics deals with problems where the portion of physical reality to be modeled spans over such a large range of spatial and temporal dimensions, that it is impossible to represent it as a single space-time continuum. We are forced to consider multiple space-time continua, each representing the phenomenon of interest at a characteristic space-time scale. Multiscale models describe a complex process across multiple scales, and account for how quantities transform as we move from one scale to another...
January 19, 2017: Wiley Interdisciplinary Reviews. Systems Biology and Medicine
https://www.readbyqxmd.com/read/28102505/maternal-characteristics-and-incidence-of-overweight-obesity-in-children-a-13-year-follow-up-study-in-an-eastern-mediterranean-population
#13
Sara Jalali-Farahani, Parisa Amiri, Behnood Abbasi, Mehrdad Karimi, Leila Cheraghi, Maryam Sadat Daneshpour, Fereidoun Azizi
Objectives To investigate clustering of parental sociobehavioral factors and their relationship with the incidence of overweight and obesity in Iranian children. Methods Demographics, body weight, and certain medical characteristics of the parents of 2999 children were used to categorize parents by cluster; children's weights were assessed for each cluster. Specifically, survival analysis and Cox regression models were used to test the effect of parental clustering on the incidence of childhood overweight and obesity...
January 19, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/28102411/defect-driven-shapes-in-nematic-droplets-analogies-with-cell-division
#14
Marco Leoni, Oksana V Manyuhina, Mark J Bowick, M Cristina Marchetti
Building on the striking similarity between the structure of the spindle during mitosis in living cells and nematic textures in confined liquid crystals, we use a continuum model of two-dimensional nematic liquid crystal droplets to examine the physical aspects of cell division. The model investigates the interplay between bulk elasticity of the microtubule assembly, described as a nematic liquid crystal, and surface elasticity of the cell cortex, modeled as a bounding flexible membrane, in controlling cell shape and division...
January 19, 2017: Soft Matter
https://www.readbyqxmd.com/read/28102401/the-effect-of-substituents-on-the-stability-of-triply-bonded-gallium-triple-bond-length-as-m-dash-antimony-molecules-a-new-target-for-synthesis
#15
Jia-Syun Lu, Ming-Chung Yang, Ming-Der Su
The effect of substitution on the potential energy surfaces of RGa(-)[triple bond, length as m-dash]Sb(+)R (R = F, OH, H, CH3, SiH3, SiMe(SitBu3)2, SiiPrDis2 and NHC) is studied using density functional theory (M06-2X/Def2-TZVP, B3PW91/Def2-TZVP and B3LYP/LANL2DZ + dp). The computational results show that all of the triply bonded RGa(-)[triple bond, length as m-dash]Sb(+)R molecules have a preference for a bent geometry (i.e., ∠RGaSb ≈ 180° and ∠GaSbR ≈ 90°), which can be described using a valence bond model...
January 19, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28102388/crystal-structure-of-ba2-la0-727ba0-182m0-091-mo6-m-nb-sb-bi-symmetry-nuance-identified-in-photoluminescence-and-ir-spectroscopy-studies
#16
Rohan Phatak, Santosh K Gupta, Priya Maheshwari, Amitabh Das, Sanjay K Sali
A one-third lanthanum deficiency was created in Ba2LaM(5+)O6 compounds (LaM compounds) to form Ba2La2/3M(5+)O5.5 compounds (La2/3M compounds) for M = Nb, Sb, and Bi. The compounds were prepared by a gel-combustion method using citric acid as a fuel. All the compounds were characterized by powder X-ray diffraction (XRD). The XRD analysis showed that the space group of the La2/3M compounds remains the same for the Bi and Sb samples when compared to the reported LaM compounds, except for the Nb sample. La2/3Nb and La2/3Sb adopt a rhombohedral structure with the space group R3[combining macron], whereas La2/3Bi adopts a monoclinic structure with the space group I2/m...
January 19, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28102384/predicting-point-defect-equilibria-across-oxide-hetero-interfaces-model-system-of-zro2-cr2o3
#17
Jing Yang, Mostafa Youssef, Bilge Yildiz
We present a multi-scale approach to predict equilibrium defect concentrations across oxide/oxide hetero-interfaces. There are three factors that need to be taken into account simultaneously for computing defect redistribution around the hetero-interfaces: the variation of local bonding environment at the interface as epitomized in defect segregation energies, the band offset at the interface, and the equilibration of the chemical potentials of species and electrons via ionic and electronic drift-diffusion fluxes...
January 19, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28102368/novel-electron-phonon-relaxation-pathway-in-graphite-revealed-by-time-resolved-raman-scattering-and-angle-resolved-photoemission-spectroscopy
#18
Jhih-An Yang, Stephen Parham, Daniel Dessau, Dmitry Reznik
Time dynamics of photoexcited electron-hole pairs is important for a number of technologies, in particular solar cells. We combined ultrafast pump-probe Raman scattering and photoemission to directly follow electron-hole excitations as well as the G-phonon in graphite after an excitation by an intense laser pulse. This phonon is known to couple relatively strongly to electrons. Cross-correlating effective electronic and phonon temperatures places new constraints on model-based fits. The accepted two-temperature model predicts that G-phonon population should start to increase as soon as excited electron-hole pairs are created and that the rate of increase should not depend strongly on the pump fluence...
January 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28102344/predicting-drug-combination-index-and-simulating-the-network-regulation-dynamics-by-mathematical-modeling-of-drug-targeted-egfr-erk-signaling-pathway
#19
Lu Huang, Yuyang Jiang, Yuzong Chen
Synergistic drug combinations enable enhanced therapeutics. Their discovery typically involves the measurement and assessment of drug combination index (CI), which can be facilitated by the development and applications of in-silico CI predictive tools. In this work, we developed and tested the ability of a mathematical model of drug-targeted EGFR-ERK pathway in predicting CIs and in analyzing multiple synergistic drug combinations against observations. Our mathematical model was validated against the literature reported signaling, drug response dynamics, and EGFR-MEK drug combination effect...
January 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28102298/erratum-longitudinal-modeling-of-ultrasensitive-and-traditional-prostate-specific-antigen-and-prediction-of-biochemical-recurrence-after-radical-prostatectomy
#20
Teemu D Laajala, Heikki Seikkula, Fatemeh Seyednasrollah, Tuomas Mirtti, Peter J Boström, Laura L Elo
No abstract text is available yet for this article.
January 19, 2017: Scientific Reports
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