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https://www.readbyqxmd.com/read/28918171/the-association-between-delirium-and-sarcopenia-in-older-adult-patients-admitted-to-acute-geriatrics-units-results-from-the-glisten-multicenter-observational-study
#1
Giuseppe Bellelli, Antonella Zambon, Stefano Volpato, Pasquale Abete, Lara Bianchi, Mario Bo, Antonio Cherubini, Francesco Corica, Mauro Di Bari, Marcello Maggio, Giovanna Maria Manca, Maria Rosaria Rizzo, Andrea Rossi, Francesco Landi
BACKGROUND & AIMS: To date, studies assessing the relationship between sarcopenia and delirium, two of the most common geriatric syndromes, are lacking. We sought to explore this association by investigating the co-occurrence of these two conditions and the independent association between them in a population of hospitalized older adults. METHODS: Cross-sectional multicenter analysis of older adults consecutively admitted to 12 acute geriatric units (AGUs). Sarcopenia was assessed upon admission by evaluating the presence of low skeletal mass index (kg/m(2)), and either low handgrip strength or low walking speed (European Working Group on Sarcopenia in Older People, EWGSOP criteria)...
September 5, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28918110/emergent-behaviors-in-rbcs-flows-in-micro-channels-using-digital-particle-image-velocimetry
#2
F Cairone, D Ortiz, P J Cabrales, M Intaglietta, M Bucolo
The key points in the design of microfluidic Lab-On-a-Chips for blood tests are the simplicity of the microfluidic chip geometry, the portability of the monitoring system and the ease on-chip integration of the data analysis procedure. The majority of those, recently designed, have been used for blood separation, however their introduction, also, for pathological conditions diagnosis would be important in different biomedical contexts. To overcome this lack is necessary to establish the relation between the RBCs flow and blood viscosity changes in micro-vessels...
September 13, 2017: Microvascular Research
https://www.readbyqxmd.com/read/28917806/portable-and-low-cost-colorimetric-office-paper-based-device-for-phenacetin-detection-in-seized-cocaine-samples
#3
Gabriela O da Silva, William R de Araujo, Thiago R L C Paixão
An office paper-based colorimetric device is proposed as a portable, rapid, and low-cost sensor for forensic applications aiming to detect phenacetin used as adulterant in illicit seized materials such as cocaine. The proposed method uses white office paper as the substrate and wax printing technology to fabricate the detection zones. Based on the optimum conditions, a linear analytical curve was obtained for phenacetin concentrations ranging from 0 to 64.52µgmL(‒1), and the straight line was in accordance with the following equation: (Magenta percentage color) = 1...
January 1, 2018: Talanta
https://www.readbyqxmd.com/read/28917795/portable-near-infrared-spectroscopy-applied-to-quality-control-of-brazilian-coffee
#4
Radigya M Correia, Flavia Tosato, Eloilson Domingos, Rayza R T Rodrigues, Luiz Felipe M Aquino, Paulo R Filgueiras, Valdemar Lacerda, Wanderson Romão
The use of portable micro-spectrometers such as a micro near infrared region (microNIR) spectrometer is a promising technique for solving analytical problems in several areas of science. This work evaluated the potential of microNIR in quality control of Arabica coffee. Arabica coffee has a high commercial value product, motivating the development of analytical methods with high sensitivity and accuracy for detection of its adulteration. Herein, microNIR was successfully used to determine the quality of Arabica coffee by identification and quantification of adulterations such as Robusta coffee (in different roasting levels), as well as corn, peels, and sticks...
January 1, 2018: Talanta
https://www.readbyqxmd.com/read/28917788/glass-polytetrafluoroethylene-glass-based-sandwich-microdevice-for-continuous-flow-polymerase-chain-reaction-and-its-application-for-fast-identification-of-foodborne-pathogens
#5
Kieu The Loan Trinh, Nae Yoon Lee
A uniquely fabricated microdevice with a glass-polytetrafluoroethylene (PTFE)-glass (GPG) sandwich configuration was developed for the fast identification of foodborne pathogens by using continuous-flow polymerase chain reaction (PCR) followed by on-site fluorescence detection of PCR products. A PTFE tube was simply folded into a serpentine configuration and sandwiched between two glass slides to maintain a 2D planar structure. By using a PTFE tube, the microchannel has the advantage of seamlessness without the need for photolithography methods, and is less expensive and less time-consuming to fabricate than alternative devices...
January 1, 2018: Talanta
https://www.readbyqxmd.com/read/28917759/detection-of-aflatoxin-b1-in-food-samples-based-on-target-responsive-aptamer-cross-linked-hydrogel-using-a-handheld-ph-meter-as-readout
#6
Mengmeng Zhao, Peilong Wang, Yajuan Guo, Lixu Wang, Fang Luo, Bin Qiu, Longhua Guo, Xiaoou Su, Zhenyu Lin, Guonan Chen
Aflatoxin B1 (AFB1) can cause great threat to human health, so the development of convenient and portable device for sensitive detection of AFB1 is highly desired. The portable pH meter has the characters of facile operation, low cost, and easy availability. Therefore, in this study, we investigate the applicability of utilizing a pH meter as the readout to develop a portable sensor for AFB1. The specific detection of AFB1 is realized via the combination of AFB1-responsive aptamer-cross-linked hydrogel. Upon the addition of AFB1, AFB1 binds to its aptamer with high affinity in lieu of aptamer/DNA complex, causing the collapse of hydrogel network and results in the releasing of urease into the solution...
January 1, 2018: Talanta
https://www.readbyqxmd.com/read/28917750/portable-near-infrared-spectroscopy-applied-to-fuel-quality-control
#7
Radigya M Correia, Eloilson Domingos, Vagne M Cáo, Brenda R F Araujo, Sthefany Sena, Layla U Pinheiro, André M Fontes, Luiz Felipe M Aquino, Ernesto C Ferreira, Paulo R Filgueiras, Wanderson Romão
Fuel quality control has gained interest in many countries owing to the potential damage of low-quality fuel to engines, the environment, and economy. Thus, the application of analytical techniques to verify quality control of fuels has become crucial. The portable micro-spectrometer in the near infrared region (microNIR) has gained credibility as a successful analytical technique in several quality control sectors. The possibility of real-time analysis using a nondestructive and reliable method is the main advantage of this methodology...
January 1, 2018: Talanta
https://www.readbyqxmd.com/read/28917688/a-randomized-trial-of-pocket-echocardiography-integrated-mobile-health-device-assessments-in-modern-structural-heart-disease-clinics
#8
Sanjeev P Bhavnani, Srikanth Sola, David Adams, Ashwin Venkateshvaran, P K Dash, Partho P Sengupta
OBJECTIVES: This study sought to determine whether mobile health (mHealth) device assessments used as clinical decision support tools at the point-of-care can reduce the time to treatment and improve long-term outcomes among patients with rheumatic and structural heart diseases (SHD). BACKGROUND: Newly developed smartphone-connected mHealth devices represent promising methods to diagnose common diseases in resource-limited areas; however, the impact of technology-based care on long-term outcomes has not been rigorously evaluated...
September 9, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28916034/colorimetric-biosensor-based-on-a-dnazyme-primer-and-its-application-in-logic-gate-operations-for-dna-screening
#9
Chenguang Wang, Nan Cheng, Longjiao Zhu, Yuancong Xu, Kunlun Huang, Pengyu Zhu, Shuifang Zhu, Wei Fu, Wentao Xu
A colorimetric biosensor for DNA screening was designed based on the conformational changes of the horseradish peroxidase (HRP)-mimicking DNAzyme. The scheme of DNA biosensing was designed based on the base pairing of DNAzyme sequence to inhibit the formation of HRP-mimicking hemin/G-quadruplex structures in the process of amplification. DNA could be amplified via the universal primer multiplex polymerase chain reaction (UP-M-PCR) and innovatively detected as color disappear in the reaction visible to the naked eye...
September 22, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28915947/immunosensor-array-platforms-based-on-self-assembled-dithiols-for-the-electrochemical-detection-of-tetrodotoxins-in-puffer-fish
#10
Laia Reverté, Katrina Campbell, Maria Rambla-Alegre, Christopher T Elliott, Jorge Diogène, Mònica Campàs
The recent detection of tetrodotoxins (TTXs) in European fish and shellfish has emphasized the urgent need to develop specific, selective, rapid and easy-to-use methods for their detection to assess the potential risk posed to human health. For this purpose, a dithiol self-assembled monolayer (SAM)-based immunoassay previously performed on maleimide plates (mELISA) has been adapted to gold electrode arrays for the development of an electrochemical immunosensor for TTX. The electrochemical SAM-based immunosensor designed herein, provided an oriented, stable and spaced sensing platform for the determination of TTX, attaining a limit of detection of 2...
October 9, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28915385/photoluminescent-lateral-flow-based-on-non-radiative-energy-transfer-for-protein-detection-in-human-serum
#11
Alejandro Zamora-Gálvez, Eden Morales-Narváez, Javier Romero, Arben Merkoçi
A new paper-based lateral flow immunoassay configuration was engineered and investigated. The assay is intended for the detection of a model protein in human serum, that is, human immunoglobulin G, with the aim to demonstrate a virtually universal protein detection platform. Once the sample is added in the strip, the analyte is selectively captured by antibody-decorated silica beads (Ab-SiO2) onto the conjugate pad and the sample flows by capillarity throughout the strip until reaching the test line, where a sandwich-like immunocomplex takes place due to the presence of antibody-functionalized QDs (Ab-QDs) onto the test line...
September 11, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28915277/a-portable-bioelectronic-sensing-system-bessy-for-environmental-deployment-incorporating-differential-microbial-sensing-in-miniaturized-reactors
#12
Alyssa Y Zhou, Moshe Baruch, Caroline M Ajo-Franklin, Michel M Maharbiz
Current technologies are lacking in the area of deployable, in situ monitoring of complex chemicals in environmental applications. Microorganisms metabolize various chemical compounds and can be engineered to be analyte-specific making them naturally suited for robust chemical sensing. However, current electrochemical microbial biosensors use large and expensive electrochemistry equipment not suitable for on-site, real-time environmental analysis. Here we demonstrate a miniaturized, autonomous bioelectronic sensing system (BESSY) suitable for deployment for instantaneous and continuous sensing applications...
2017: PloS One
https://www.readbyqxmd.com/read/28914453/potential-effectiveness-of-visible-and-near-infrared-spectroscopy-coupled-with-wavelengths-selection-for-real-time-grapevine-leaf-water-status-measurement
#13
Valentina Giovenzana, Roberto Beghi, Simone Parisi, Lucio Brancadoro, Riccardo Guidetti
BACKGROUND: Increasing attention is paid to non-destructive methods for water status real time monitoring as a potential solution, replacing the tedious conventional techniques which are time consuming and not easily to perform directly in field. The objective was to test the potential effectiveness of two portable optical devices (visible/near infrared, vis/NIR; and near infrared, NIR) for a rapid and non-destructive evaluation of the water status of grapevine leaves. Moreover, a variable selection methodology was proposed to determine a set of candidate variables for the prediction of water potential (Ψ; MPa) related to leaf water status in a view of a simplified optical device...
September 15, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28914268/impact-of-hipaa-s-minimum-necessary-standard-on-genomic-data-sharing
#14
Barbara J Evans, Gail P Jarvik
This article provides a brief introduction to the Health Insurance Portability and Accountability Act of 1996 (HIPAA) Privacy Rule's minimum necessary standard, which applies to sharing of genomic data, particularly clinical data, following 2013 Privacy Rule revisions. This research used the Thomson Reuters Westlaw database and law library resources in its legal analysis of the HIPAA privacy tiers and the impact of the minimum necessary standard on genomic data sharing. We considered relevant example cases of genomic data-sharing needs...
September 14, 2017: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/28913283/reduction-of-zygomatic-arch-isolated-fracture-using-ultra-sound-and-needle-marking
#15
Jun Sik Kim, Young Ji Park, Yoon Jung Lee, Nam Gyun Kim, Kyung Suk Lee
BACKGROUND: Zygomatic arch is a bony arch constituting the lateral midface, which consists of 25% of all midface fractures. There are a number of ways to evaluate the extent of zygomatic arch fracture. Some authors have reported successful treatment outcomes using ultrasound (U/S). To add to the previous methods, we have considered ways to accurately display the location of the fracture line while using U/S with 23 gauge needle marking. We introduce our method, which provided satisfactory results for reduction using a portable U/S, and it can evaluate the fracture line simultaneously when reduction of an isolated zygomatic arch fracture is necessary, and needle marking, which can easily point out the fracture line on U/S...
December 2016: Arch Craniofac Surg
https://www.readbyqxmd.com/read/28913168/feasibility-of-photoacoustic-ultrasound-imaging-of-synovitis-in-finger-joints-using-a-point-of-care-system
#16
Pim J van den Berg, Khalid Daoudi, Hein J Bernelot Moens, Wiendelt Steenbergen
We evaluate a portable ultrasound and photoacoustic imaging (PAI) system for the feasibility of a point-of-care assessment of clinically evident synovitis. Inflamed and non-inflamed proximal interphalangeal joints of 10 patients were examined and compared with joints from 7 healthy volunteers. PAI scans, ultrasound power Doppler (US-PD), and clinical examination were performed. We quantified the amount of photoacoustic (PA) signal using a region of interest (ROI) drawn over the hypertrophic joint space. PAI response was increased 4 to 10 fold when comparing inflamed with contralateral non-inflamed joints and with joints from healthy volunteers (p < 0...
December 2017: Photoacoustics
https://www.readbyqxmd.com/read/28912562/flexible-supercapacitor-electrodes-based-on-real-metal-like-cellulose-papers
#17
Yongmin Ko, Minseong Kwon, Wan Ki Bae, Byeongyong Lee, Seung Woo Lee, Jinhan Cho
The effective implantation of conductive and charge storage materials into flexible frames has been strongly demanded for the development of flexible supercapacitors. Here, we introduce metallic cellulose paper-based supercapacitor electrodes with excellent energy storage performance by minimizing the contact resistance between neighboring metal and/or metal oxide nanoparticles using an assembly approach, called ligand-mediated layer-by-layer assembly. This approach can convert the insulating paper to the highly porous metallic paper with large surface areas that can function as current collectors and nanoparticle reservoirs for supercapacitor electrodes...
September 14, 2017: Nature Communications
https://www.readbyqxmd.com/read/28912515/screening-for-vision-threatening-diabetic-retinopathy-in-south-india-comparing-portable-non-mydriatic-and-standard-fundus-cameras-and-clinical-exam
#18
S Sengupta, M D Sindal, C G Besirli, S Upadhyaya, R Venkatesh, L M Niziol, A L Robin, M A Woodward, P A Newman-Casey
PurposeTo evaluate the sensitivity and specificity of a portable non-mydriatic fundus camera to diagnose vision-threatening diabetic retinopathy (VTDR).Patients and methodsA prospective, single-site, comparative instrument validation study was undertaken at the Aravind Eye Care System. Overall, 155 subjects with and without diabetes were recruited. Images from 275 eyes were obtained with the (1) non-mydriatic Smartscope, (2) mydriatic Smartscope, and (3) mydriatic table-top camera of the macular, nasal, and superotemporal fields...
September 15, 2017: Eye
https://www.readbyqxmd.com/read/28912188/modern-imaging-techniques-in-cardiomyopathies
#19
REVIEW
M Fuad Jan, A Jamil Tajik
Modern advanced imaging techniques have allowed increasingly more rigorous assessment of the cardiac structure and function of several types of cardiomyopathies. In contemporary cardiology practice, echocardiography and cardiac magnetic resonance imaging are widely used to provide a basic framework in the evaluation and management of cardiomyopathies. Echocardiography is the quintessential imaging technique owing to its unique ability to provide real-time images of the beating heart with good temporal resolution, combined with its noninvasive nature, cost-effectiveness, availability, and portability...
September 15, 2017: Circulation Research
https://www.readbyqxmd.com/read/28911333/profiling-bacterial-communities-by-minion-sequencing-of-ribosomal-operons
#20
Lee J Kerkhof, Kevin P Dillon, Max M Häggblom, Lora R McGuinness
BACKGROUND: An approach utilizing the long-read capability of the Oxford Nanopore MinION to rapidly sequence bacterial ribosomal operons of complex natural communities was developed. Microbial fingerprinting employs domain-specific forward primers (16S rRNA subunit), reverse primers (23S rRNA subunit), and a high-fidelity Taq polymerase with proofreading capabilities. Amplicons contained both ribosomal subunits for broad-based phylogenetic assignment (~ 3900 bp of sequence), plus the intergenic spacer (ITS) region (~ 300 bp) for potential strain-specific identification...
September 15, 2017: Microbiome
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